Abstract:
OBJECTIVE:To examine whether socioeconomic status (SES) (education, occupation, income), is associated both cross sectionally and prospectively with circulating concentrations of a) two correlates of oxidative damage, F(2)-isoprostanes (F(2)-IsoPs) and gamma-glutamyltransferase (GGT); and b) antioxidant nutrients (ascorbic acid and carotenoids). We also examine whether the proposed associations are mediated by smoking, alcohol consumption, and depression. Risk for chronic disease increases with decreasing SES. One pathway by which low SES might influence disease risk is by promoting oxidative stress. METHODS:Data from 1278 participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study were used to examine the association of SES with oxidation correlates and antioxidant nutrients. Education, occupation, health behaviors, and body mass index (BMI) were assessed during Years 0, 10, and 15 of the study; income and depression were evaluated at Years 10 and 15. F(2)-isoprostanes were measured at Year 15, gamma-glutamyltransferase (GGT) at Years 0 and 10, carotenoids at Years 0 and 15, and ascorbic acid at Years 10 and 15. RESULTS:Cross sectionally, oxidation correlates decreased and antioxidant nutrients increased with increasing SES, estimated in several ways, independent of age, sex, race, and BMI. Prospectively, lower Year 0 education and occupation predicted greater increases in GGT and greater decreases in carotenoids over 10 to 15 years. Prospective associations of Year 0 SES with Year 15 carotenoids were independent of Year 15 SES. Smoking, drinking, and depression symptoms partially mediated these effects. CONCLUSIONS:Circulating oxidation correlates increase and antioxidant nutrients decrease with decreasing SES, both cross sectionally and prospectively.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Janicki-Deverts D,Cohen S,Matthews KA,Gross MD,Jacobs DR Jrdoi
10.1097/PSY.0b013e31819e7526subject
Has Abstractpub_date
2009-06-01 00:00:00pages
541-8issue
5eissn
0033-3174issn
1534-7796pii
PSY.0b013e31819e7526journal_volume
71pub_type
杂志文章abstract::MMPI measures of neuroticism (N) and of cynicism (C) were obtained at the initial examination of 1871 employed, middle-aged men in Chicago. Neither N nor C was significantly associated cross-sectionally with systolic blood pressure or serum cholesterol, but both were positively associated with cigarette smoking and al...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199103000-00006
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVES:Research on the health of workers involved in the cleanup after the attack on the World Trade Center (WTC) on September 11, 2001, has documented high rates of psychological distress and upper gastrointestinal (GI) symptoms. The current article examines the concurrent and longitudinal associations of psycholo...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000116
更新日期:2014-11-01 00:00:00
abstract::Sixty subjects classified as either Type A or Type B interacted in pairs by pressing buttons which transmitted messages through a television screen while the heart rate and digital blood volume pulse were computer-monitored. Partners could cooperate, compete, punish, reward, or withdraw on each interaction and could s...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197902000-00002
更新日期:1979-02-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/PSY.0000000000000168
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The proportion of overweight and obese people has grown rapidly, and obesity has now been widely recognized as an important public health problem. At the same time, stress has increased in working life. The 2 problems could be connected if work stress promotes unhealthy eating habits and sedentary behavior an...
journal_title:Psychosomatic medicine
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doi:10.1097/01.psy.0000170330.08704.62
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:The American Diabetes Association recently called for research on social and environmental determinants of diabetes to intensify primary prevention. Recent epidemiological evidence suggests that frequent and modifiable psychosocial stressors at work might contribute to the development of diabetes, but more pr...
journal_title:Psychosomatic medicine
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doi:10.1097/PSY.0000000000000898
更新日期:2020-12-15 00:00:00
abstract:OBJECTIVE:Both depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity. METHODS:Patients with ACS ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318268978e
更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/00006842-199011000-00001
更新日期:1990-11-01 00:00:00
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journal_title:Psychosomatic medicine
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doi:10.1097/00006842-198701000-00004
更新日期:1987-01-01 00:00:00
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更新日期:2012-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/00006842-199611000-00010
更新日期:1996-11-01 00:00:00
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doi:10.1097/PSY.0b013e3182689460
更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0b013e31825e3578
更新日期:2012-09-01 00:00:00
abstract::Depression is a well-known reaction to separation in all species of macaques studied except the bonnet (M. radiata), in whom this reaction has never before been observed. We have produced the depressive response of postural collapse and social withdrawal in a bonnet infant by altering the social structure of the group...
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pub_type: 杂志文章
doi:10.1097/00006842-197802000-00008
更新日期:1978-02-01 00:00:00
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doi:10.1097/PSY.0b013e31823a5b2f
更新日期:2012-01-01 00:00:00
abstract::Despite advances in HIV treatment, there continues to be great variability in the progression of this disease. This paper reviews the evidence that depression, stressful life events, and trauma account for some of the variation in HIV disease course. Longitudinal studies both before and after the advent of highly acti...
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pub_type: 杂志文章,评审
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更新日期:2008-06-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000097331.10458.f1
更新日期:2003-11-01 00:00:00
abstract::Psychosocial work characteristics, such as work demand, work control, and social support at work, have been shown to be related to the development of coronary heart disease in epidemiological studies. However, the mechanisms which mediate the social and psychological effects on the cardiovascular system are not known....
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/00006842-199101000-00005
更新日期:1991-01-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1097/00006842-198809000-00003
更新日期:1988-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2008-05-01 00:00:00
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更新日期:2003-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000474
更新日期:2017-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2007-01-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199911000-00023
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare baseline levels of salivary cortisol, diurnal cortisol slopes, and cortisol reactivity to a mammogram in breast cancer survivors and women without a history of cancer. METHODS:Participants were 33 breast cancer survivors (3-5 years postdiagnosis) and 21 women with no ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000088595.91705.c5
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:This study investigates psychological and psychobiological processes in patients with somatization syndrome. METHOD:We compared physiological measures (heart rate, finger pulse volume, electrodermal activity, electromyography), cortisol levels, and subjective well-being during rest and during a mental stress...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199803000-00016
更新日期:1998-03-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 历史文章,杂志文章
doi:10.1097/00006842-199909000-00002
更新日期:1999-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000100
更新日期:2014-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.psy.0000128900.13711.5b
更新日期:2004-07-01 00:00:00