Globus sensation and psychopathology in men: the Vietnam experience study.

Abstract:

OBJECTIVE:To assess whether globus is associated with psychopathology in men. Globus-a persistent sensation of having a lump in the throat with no detectable physical cause-has long been thought a predominantly female disorder. Several small studies, based wholly or largely on women, suggested that globus is associated with higher levels of depression, anxiety, and somatic concern. METHODS:Participants were 4240 male U.S. veterans who underwent detailed medical and psychological examinations in middle age. Psychological health was assessed by structured diagnostic interview and the clinical scales of the Minnesota Multiphasic Personality Inventory (MMPI). The MMPI includes an item on the presence of globus. RESULTS:The prevalence of globus was 6.4%. Men with globus had an increased risk of being diagnosed with somatization disorder, odds ratio (OR) = 5.92, 95% Confidence Interval (CI) = 3.22, 10.9l; major depression, OR = 4.98, 95% CI = 3.63, 6.67; generalized anxiety disorder, OR = 3.70, 95% CI = 2.75, 4.90; posttraumatic stress disorder, OR = 3.50, 95% CI = 2.54, 4.76; and drug abuse or dependence, OR = 1.89, 95% CI = 1.15, 3.13; and they scored significantly higher on nine of the ten MMPI clinical scales. Globus was also associated with lower cognitive ability, socioeconomic and educational disadvantage, a higher pulse rate, and increased likelihood of being on antihypertensive medication. CONCLUSIONS:Globus is linked with a wide range of psychopathology in men, notably depression and somatization disorder. Men presenting with globus might have developed that particular symptom to "represent" other, related and treatable psychopathology, which should also be investigated.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Gale CR,Wilson JA,Deary IJ

doi

10.1097/PSY.0b013e3181bc7739

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

1026-31

issue

9

eissn

0033-3174

issn

1534-7796

pii

PSY.0b013e3181bc7739

journal_volume

71

pub_type

杂志文章
  • Thresholds and perception of cold pain, heat pain, and the thermal grill illusion in patients with major depressive disorder.

    abstract:OBJECTIVE:The thermal grill illusion (TGI) in which interlacing cold and warm bars create the illusion of a painful sensation has been suggested as an experimental model for central pain states and pain processing. The aim of this study was to use this technique to gain further insights into the altered pain perception...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182881a9c

    authors: Boettger MK,Grossmann D,Bär KJ

    更新日期:2013-04-01 00:00:00

  • Negative behavior during marital conflict is associated with immunological down-regulation.

    abstract::Although increased morbidity and mortality have been reliably associated with social isolation and less satisfying personal relationships, relatively little is known about the underlying biopsychosocial mechanisms. We assessed problem-solving behaviors and changes in immune function in 90 newlywed couples who were adm...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199309000-00001

    authors: Kiecolt-Glaser JK,Malarkey WB,Chee M,Newton T,Cacioppo JT,Mao HY,Glaser R

    更新日期:1993-09-01 00:00:00

  • Association of baseline anxiety with depression persistence at 6 months in patients with acute cardiac illness.

    abstract:OBJECTIVE:To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization. METHODS:Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhy...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e31823d38bc

    authors: Celano CM,Mastromauro CA,Lenihan EC,Januzzi JL,Rollman BL,Huffman JC

    更新日期:2012-01-01 00:00:00

  • Premenstrual changes and affective disorders.

    abstract::The differential relationship between specific subtypes of premenstrual changes and specific subtypes of mental disorder was studied. Premenstrual changes were evaluated with the Premenstrual Assessment Form, which provides specific criteria for the classification of the various subtypes of premenstrual change. The Re...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198112000-00008

    authors: Endicott J,Halbreich U,Schacht S,Nee J

    更新日期:1981-12-01 00:00:00

  • A comparison of cook-medley hostility subscales and mortality in patients with coronary heart disease: data from the heart and soul study.

    abstract:OBJECTIVE:Hostility is associated with adverse outcomes in patients with coronary heart disease (CHD). However, assessment tools used to evaluate hostility in epidemiological studies vary widely. METHODS:We administered nine subscales of the Cook-Medley Hostility Scale (CMHS) to 656 outpatients with stable CHD between...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000059

    authors: Wong JM,Sin NL,Whooley MA

    更新日期:2014-05-01 00:00:00

  • Generalized anxiety disorder and peptic ulcer disease among adults in the United States.

    abstract:OBJECTIVE:Previous research has suggested a link between chronic anxiety and peptic ulcer disease, though recent evidence documenting an infectious cause (Helicobacter pylori) for ulcer has led to doubt about this association. The goal of the current study was to determine the relationship between generalized anxiety d...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000038935.67401.f3

    authors: Goodwin RD,Stein MB

    更新日期:2002-11-01 00:00:00

  • Infection load as a predisposing factor for somatoform disorders: evidence from a Dutch General Practice Registry.

    abstract:OBJECTIVE:Somatoform disorders (SDs) are characterized by chronic multiple functional somatic (FS) symptoms. It has been suggested that infections may be triggers for FS symptoms to occur, pointing to the immune system as a pathogenic factor in their development. The current study aimed to compare the prevalence of inf...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182a3d91f

    authors: Lacourt TE,Houtveen JH,Smeets HM,Lipovsky MM,van Doornen LJ

    更新日期:2013-10-01 00:00:00

  • Nighttime heart rate and survival in depressed patients post acute myocardial infarction.

    abstract:OBJECTIVES:To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is a risk factor for mortality post AMI. It is also associated with ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181835ca3

    authors: Carney RM,Steinmeyer B,Freedland KE,Blumenthal JA,Stein PK,Steinhoff WA,Howells WB,Berkman LF,Watkins LL,Czajkowski SM,Domitrovich PP,Burg MM,Hayano J,Jaffe AS

    更新日期:2008-09-01 00:00:00

  • Depression and smoking in coronary heart disease.

    abstract:OBJECTIVE:This review examines the relationship between depression and smoking in coronary heart disease (CHD). It summarizes relevant findings from general population and smoking cessation studies and discusses the few studies that have investigated whether smoking confounds, mediates, or moderates the effect of depre...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.psy.0000162255.55629.9c

    authors: Freedland KE,Carney RM,Skala JA

    更新日期:2005-05-01 00:00:00

  • Momentary work worries, marital disclosure, and salivary cortisol among parents of young children.

    abstract:OBJECTIVE:To investigate whether worries about work are linked to people's own cortisol levels and their spouses' cortisol levels in everyday life and whether marital factors may moderate these links. Although research has shown that satisfying marriages can buffer the physiological effects of everyday stress, the spec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181f60fcc

    authors: Slatcher RB,Robles TF,Repetti RL,Fellows MD

    更新日期:2010-11-01 00:00:00

  • Perceptions of parental caring predict health status in midlife: a 35-year follow-up of the Harvard Mastery of Stress Study.

    abstract:OBJECTIVE:This study examined how the perception of parental caring, obtained from undergraduates, relates to subsequent health over the ensuing 35 years. METHODS:In the early 1950s, initial ratings of parental caring were obtained from a sample of healthy, Harvard undergraduate men who participated in the Harvard Mas...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199703000-00005

    authors: Russek LG,Schwartz GE

    更新日期:1997-03-01 00:00:00

  • Genetic vulnerability and phenotypic expression of depression and risk for ischemic heart disease in the Vietnam era twin study of aging.

    abstract:OBJECTIVE:To determine if depression contributes to incident heart disease after accounting for genetic, behavioral, and medical factors associated with both conditions. METHODS:We used a prospective twin study with a 12-year follow-up. In 1992, lifetime diagnosis of depression was assessed in 1159 male-male twins and...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e3181d28125

    authors: Xian H,Scherrer JF,Franz CE,McCaffery J,Stein PK,Lyons MJ,Jacobsen K,Eisen SA,Kremen WS

    更新日期:2010-05-01 00:00:00

  • Cortisol levels and responses to mammography screening in breast cancer survivors: a pilot study.

    abstract:OBJECTIVE:The purpose of this study was to compare baseline levels of salivary cortisol, diurnal cortisol slopes, and cortisol reactivity to a mammogram in breast cancer survivors and women without a history of cancer. METHODS:Participants were 33 breast cancer survivors (3-5 years postdiagnosis) and 21 women with no ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000088595.91705.c5

    authors: Porter LS,Mishel M,Neelon V,Belyea M,Pisano E,Soo MS

    更新日期:2003-09-01 00:00:00

  • Effects of chronic stress on beta-adrenergic receptors in the homeless.

    abstract::This study examined the role of chronic life stress (homelessness), coping style, and hypertension on beta-adrenergic receptors in a sample of homeless men. Sixteen healthy normotensive subjects and nine untreated hypertensive subjects were studied. Life stress was measured with the Brown and Harris categorization; co...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199407000-00003

    authors: Dimsdale JE,Mills P,Patterson T,Ziegler M,Dillon E

    更新日期:1994-07-01 00:00:00

  • Blood pressure response to the "second cup of coffee".

    abstract::Twenty young male coffee-drinkers consumed 150 mg of caffeine in decaffeinated coffee three times a day for 8 days. On days 3, 4, 7, and 8, caffeine or a placebo was administered in the laboratory at 11 A.M., 8 A.M., 11 A.M., and 8 A.M., respectively, in a randomized double-blind crossover design. There was a blood pr...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199005000-00007

    authors: Goldstein IB,Shapiro D,Hui KK,Yu JL

    更新日期:1990-05-01 00:00:00

  • Interactive effects of race and depressive symptoms on calcification in African American and white women.

    abstract:OBJECTIVE:To examine the cross-sectional associations among race, depressive symptoms, and aortic and coronary calcification in a sample of middle-aged women. Depressive symptoms have been associated with atherosclerotic indicators of coronary heart disease (CHD) in white women. Few studies have examined these associat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/PSY.0b013e31819080e5

    authors: Lewis TT,Everson-Rose SA,Colvin A,Matthews K,Bromberger JT,Sutton-Tyrrell K

    更新日期:2009-02-01 00:00:00

  • Social integration and mortality in patients with coronary heart disease: findings from the Heart and Soul Study.

    abstract:OBJECTIVE:To determine why lower social integration predicts higher mortality in patients with coronary heart disease (CHD). METHODS:The association between social integration and mortality was examined prospectively in 1019 outpatients with stable CHD from the Heart and Soul Study. Baseline social integration was ass...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000100

    authors: Kreibig SD,Whooley MA,Gross JJ

    更新日期:2014-10-01 00:00:00

  • Psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans.

    abstract::Recent research with animals has indicated a central nervous system effect on the immune system. This report describes findings of a possible psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans. Seven tuberculin positive subjects evidenced a decreased response to tuberculin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198303000-00009

    authors: Smith GR Jr,McDaniel SM

    更新日期:1983-03-01 00:00:00

  • The Role of Disadvantaged Neighborhood Environments in the Association of John Henryism With Hypertension and Obesity.

    abstract:OBJECTIVE:The John Henryism hypothesis proposes that high-effort, active coping in impoverished, low-resource environments is associated with an increased risk of cardiovascular disease, but a lower risk of disease in a high-resource environment. To test this hypothesis, we examined the association of John Henryism Act...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000308

    authors: Booth JM,Jonassaint CR

    更新日期:2016-06-01 00:00:00

  • Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects.

    abstract:OBJECTIVE:Ambulatory saliva collections for subsequent analysis of free cortisol levels are now frequently applied to measure adrenocortical activity in healthy subjects and patient populations. Despite the prime importance of accurate timing of saliva collection outside the laboratory, no data are available on the com...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000058374.50240.bf

    authors: Kudielka BM,Broderick JE,Kirschbaum C

    更新日期:2003-03-01 00:00:00

  • Are stress-induced cortisol changes during pregnancy associated with postpartum depressive symptoms?

    abstract:OBJECTIVE:The purpose of this study was to examine the association between psychobiological stress reactivity during healthy pregnancy and depressive symptoms in the early puerperium. METHODS:A sample of healthy nulliparous pregnant women (N = 57) between the ages of 21 and 35 years underwent a standardized psychosoci...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000244385.93141.3b

    authors: Nierop A,Bratsikas A,Zimmermann R,Ehlert U

    更新日期:2006-11-01 00:00:00

  • Mental disorders and hypertension: factors associated with awareness and treatment of hypertension in the general population of Germany.

    abstract:OBJECTIVE:The aim of the present study was to identify the association between mental disorders and awareness and treatment of hypertension in a large representative community sample. METHODS:The analysis was based on data from 4149 respondents, ages 18 to 65 years, from the German National Health Interview and Examin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000204883.77284.6b

    authors: Schmitz N,Thefeld W,Kruse J

    更新日期:2006-03-01 00:00:00

  • Stressful life events and survival after breast cancer.

    abstract:OBJECTIVE:This study assessed the relation of stressful life events with survival after breast cancer. METHODS:This study was based on women with histologically confirmed, newly diagnosed, localized or regional stage breast cancer first treated in 1 of 11 Quebec City (Canada) hospitals from 1982 through 1984. Among 76...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200103000-00017

    authors: Maunsell E,Brisson J,Mondor M,Verreault R,Deschcnes L

    更新日期:2001-03-01 00:00:00

  • Impact of Wartime Stress Exposures and Mental Health on Later-Life Functioning and Disability in Vietnam-Era Women Veterans: Findings From the Health of Vietnam-Era Women's Study.

    abstract:OBJECTIVE:The effect of stress exposures and mental health sequelae on health-related outcomes is understudied among older women veterans. We examined a) the impact of wartime stress exposures on later-life functioning and disability in Vietnam-era women veterans and b) the extent to which mental health conditions know...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000762

    authors: Smith BN,Spiro A,Frayne SM,Kimerling R,Cypel Y,Reinhard MJ,Kilbourne AM,Magruder KM

    更新日期:2020-02-01 00:00:00

  • Depression and stress reactivity in metastatic breast cancer.

    abstract:OBJECTIVE:Cancer-related distress due to the psychological and physical challenges of metastatic breast cancer (MBC) may result in symptoms of depression, which negatively affects quality and may influence quantity of life. This study investigated how depression affects MBC stress reactivity, including autonomic (ANS) ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000238216.88515.e5

    authors: Giese-Davis J,Wilhelm FH,Conrad A,Abercrombie HC,Sephton S,Yutsis M,Neri E,Taylor CB,Kraemer HC,Spiegel D

    更新日期:2006-09-01 00:00:00

  • Women with eating disorder tendencies display altered cardiovascular, neuroendocrine, and psychosocial profiles.

    abstract:OBJECTIVE:Cardiovascular, neuroendocrine, and psychosocial profiles were investigated in women with eating disorder tendencies, but who had never met clinical criteria for an eating disorder, and in healthy controls. METHODS:Twenty-six women who scored in the highest distribution of the Eating Disorder Inventory bulim...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200007000-00013

    authors: Koo-Loeb JH,Costello N,Light KC,Girdler SS

    更新日期:2000-07-01 00:00:00

  • Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder.

    abstract::This study was designed to investigate relationships between serum thyroid hormone levels and the severity of posttraumatic stress disorder (PTSD) symptoms in a group of 65 male Vietnam combat veterans who participated as members of cohorts in an elective inpatient treatment program. Thyroid hormone measures included ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199507000-00012

    authors: Wang S,Mason J,Southwick S,Johnson D,Lubin H,Charney D

    更新日期:1995-07-01 00:00:00

  • Characteristics of Autonomic Activity and Reactivity During Rest and Emotional Processing and Their Clinical Correlations in Somatic Symptom Disorder.

    abstract:OBJECTIVE:Altered autonomic nervous system activity is considered to be involved in the pathophysiology of somatic symptom disorder (SSD). This study aimed to investigate whether patients with SSD have disturbed autonomic activity during rest and reactivity to emotional processing and whether altered autonomic nervous ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000622

    authors: Lee D,Kim SJ,Cheon J,Hwang EH,Jung YC,Kang JI

    更新日期:2018-10-01 00:00:00

  • Quality of life after self-management cancer rehabilitation: a randomized controlled trial comparing physical and cognitive-behavioral training versus physical training.

    abstract:OBJECTIVE:To conduct a randomized controlled trial and compare the effects on cancer survivors' quality of life in a 12-week group-based multidisciplinary self-management rehabilitation program, combining physical training (twice weekly) and cognitive-behavioral training (once weekly) with those of a 12-week group-base...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e31816e038f

    authors: Korstjens I,May AM,van Weert E,Mesters I,Tan F,Ros WJ,Hoekstra-Weebers JE,van der Schans CP,van den Borne B

    更新日期:2008-05-01 00:00:00

  • Insomnia and depression prior to myocardial infarction.

    abstract::Insomnia is common among patients who subsequently experience an acute myocardial infarction (MI), and is a major symptom of psychiatric depression. The purpose of this study was to determine what proportion of patients reporting insomnia prior to MI have depression. Of 70 patients with a recent MI, 27 (39%) reported ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199011000-00001

    authors: Carney RM,Freedland KE,Jaffe AS

    更新日期:1990-11-01 00:00:00