Effects of chronic stress on beta-adrenergic receptors in the homeless.

Abstract:

:This study examined the role of chronic life stress (homelessness), coping style, and hypertension on beta-adrenergic receptors in a sample of homeless men. Sixteen healthy normotensive subjects and nine untreated hypertensive subjects were studied. Life stress was measured with the Brown and Harris categorization; coping style was measured with the Ways of Coping Scale. Lymphocyte beta-adrenergic receptors were characterized in terms of receptor density (Bmax). Individuals with high life stress had lower Bmax (p < .005). In multiple regression analyses, 50% of the variance in Bmax was accounted for by life stress and coping style (p = .01). Receptor measures may be useful for characterizing the physiological response to continuing life adversity.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Dimsdale JE,Mills P,Patterson T,Ziegler M,Dillon E

doi

10.1097/00006842-199407000-00003

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

290-5

issue

4

eissn

0033-3174

issn

1534-7796

journal_volume

56

pub_type

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