Thresholds and perception of cold pain, heat pain, and the thermal grill illusion in patients with major depressive disorder.

Abstract:

OBJECTIVE:The thermal grill illusion (TGI) in which interlacing cold and warm bars create the illusion of a painful sensation has been suggested as an experimental model for central pain states and pain processing. The aim of this study was to use this technique to gain further insights into the altered pain perception in major depressive disorder (MDD). METHODS:In 18 unmedicated patients with MDD, cold and heat pain thresholds (CPT/HPT) as well as the perception of the TGI were examined and compared with 18 matched controls. RESULTS:CPT and HPT were significantly increased in patients (7.9°C and 47.5°C) compared with controls (15.9°C and 45.2°C, respectively; p < .05). In the range of TGI stimuli that were perceived painful by controls, the patients did not indicate painful sensations, thereby indicating a shift of the stimulus-response curve of TGI pain perception toward higher stimulus intensities, that is, greater temperature differentials between cold and warm bars (11.5°C for controls, 16.7°C for patients). The patients rated the pain intensity perceived at the respective pain thresholds (CPT and HPT) in tendency higher than did the controls, whereas they perceived the TGI less painful despite increased stimulus intensities. Unpleasantness ratings were similar between groups. CONCLUSIONS:CPT, HPT and temperature differentials for the perception of the TGI, were increased in patients with MDD as compared with controls. Pain intensity, however, was rated differently for CPT and HPT, where patients indicated higher ratings in tendency, and for the TGI stimulation, where pain was perceived less intense.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Boettger MK,Grossmann D,Bär KJ

doi

10.1097/PSY.0b013e3182881a9c

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

281-7

issue

3

eissn

0033-3174

issn

1534-7796

pii

PSY.0b013e3182881a9c

journal_volume

75

pub_type

杂志文章
  • Intervention for minor depression in primary care patients.

    abstract::This study examines the effectiveness of an intervention for minor depression in primary care patients. One hundred fifty public care medical patients were randomly assigned to either an 8-week cognitive-behavioral course intended to help them use pleasant activities, constructive thinking, and interpersonal relations...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199403000-00009

    authors: Miranda J,Muñoz R

    更新日期:1994-03-01 00:00:00

  • Relationships Matter: Progress and Challenges in Research on the Health Effects of Intimate Relationships.

    abstract::Social connections play an important role in health and disease and provide opportunities for clinical and public health interventions. Marriage and similar intimate relationships play a central role in the potential health benefits of positive social connections. This editorial provides an integrative perspective on ...

    journal_title:Psychosomatic medicine

    pub_type: 评论,社论

    doi:10.1097/PSY.0000000000000660

    authors: Smith TW

    更新日期:2019-01-01 00:00:00

  • Social integration and mortality in patients with coronary heart disease: findings from the Heart and Soul Study.

    abstract:OBJECTIVE:To determine why lower social integration predicts higher mortality in patients with coronary heart disease (CHD). METHODS:The association between social integration and mortality was examined prospectively in 1019 outpatients with stable CHD from the Heart and Soul Study. Baseline social integration was ass...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000100

    authors: Kreibig SD,Whooley MA,Gross JJ

    更新日期:2014-10-01 00:00:00

  • Intimate partner violence and mental health consequences in women attending family practice in Spain.

    abstract:OBJECTIVE:Despite the abundant literature on the consequences of intimate partner violence (IPV) on mental health, psychological abuse has rarely been considered, and the separate effects of the different types of IPV have been understudied. The aim of this study was to analyze the association between physical, psychol...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000181269.11979.cd

    authors: Ruiz-Pérez I,Plazaola-Castaño J

    更新日期:2005-09-01 00:00:00

  • Influence of a "warm touch" support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol.

    abstract:OBJECTIVE:To investigate whether a support intervention (warm touch enhancement) influences physiological stress systems that are linked to important health outcomes. Growing evidence points to a protective effect of social and emotional support on both morbidity and mortality. METHODS:In this study, 34 healthy marrie...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e318187aef7

    authors: Holt-Lunstad J,Birmingham WA,Light KC

    更新日期:2008-11-01 00:00:00

  • Acute psychological stress: effects on chemotaxis and cellular adhesion molecule expression.

    abstract:OBJECTIVE:Activation of a psychological stress response increases autonomic activity and enhances immune function by inducing a significant increase in numbers of leukocytes at sites of inflammation. Chemotaxis and cellular adhesion are thought to mediate leukocyte trafficking. In this study, we examine the effects of ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000079377.86193.a8

    authors: Redwine L,Snow S,Mills P,Irwin M

    更新日期:2003-07-01 00:00:00

  • Depression and coronary artery atherosclerosis and reactivity in female cynomolgus monkeys.

    abstract:OBJECTIVE:Depression and coronary heart disease (CHD) are comorbid conditions, and it is thought that depression may increase the risk of CHD. However, the evidence for the latter relationship is sparse and difficult to collect. Cynomolgus monkeys (Macaca fascicularis) have been used effectively as animal models of CHD...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000021951.59258.c7

    authors: Shively CA,Williams JK,Laber-Laird K,Anton RF

    更新日期:2002-09-01 00:00:00

  • Genetic influence on blood pressure and underlying hemodynamics measured at rest and during stress.

    abstract:OBJECTIVE:This study examined the genetic and environmental contributions to the individual differences in blood pressure (BP) levels and underlying hemodynamic characteristics at rest and during mental challenge tasks in a large twin cohort of youth. Including both European American and African American twins further ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31828d3cb6

    authors: Wu T,Treiber FA,Snieder H

    更新日期:2013-05-01 00:00:00

  • Daily psychological demands are associated with 6-year progression of carotid artery atherosclerosis: the Pittsburgh Healthy Heart Project.

    abstract:OBJECTIVE:We examine associations between the perception of ongoing psychological demands by ecological momentary assessment (EMA) and 6-year changes in carotid artery atherosclerosis by ultrasonography. METHODS:A total of 270 initially healthy participants collected ambulatory blood pressure (ABP) and recorded their ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182572599

    authors: Kamarck TW,Shiffman S,Sutton-Tyrrell K,Muldoon MF,Tepper P

    更新日期:2012-05-01 00:00:00

  • Depression and risk of heart failure among the elderly: a prospective community-based study.

    abstract:OBJECTIVE:Although the association between depression and the incidence of coronary heart disease has been established in many studies, the impact of depression on the incidence of heart failure has not been previously investigated. METHODS:We examined the effect of depression (assessed by means of the Center for Epid...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200201000-00002

    authors: Williams SA,Kasl SV,Heiat A,Abramson JL,Krumholz HM,Vaccarino V

    更新日期:2002-01-01 00:00:00

  • Life stresses and premature labor: real connection or artifactual findings?

    abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198605000-00006

    authors: Omer H,Friedlander D,Palti Z,Shekel I

    更新日期:1986-05-01 00:00:00

  • Anxiety but not depression is associated with elevated blood pressure in a community group of French elderly.

    abstract:OBJECTIVE:This study examined whether anxiety and depression were independently associated with elevated blood pressure in elderly persons. METHOD:The study group consisted of 1389 subjects aged 59 to 71 years recruited from the electoral rolls of the city of Nantes (France). Subjects completed the Center for Epidemio...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199901000-00013

    authors: Paterniti S,Alpérovitch A,Ducimetière P,Dealberto MJ,Lépine JP,Bisserbe JC

    更新日期:1999-01-01 00:00:00

  • Stimulated production of proinflammatory cytokines covaries inversely with heart rate variability.

    abstract:OBJECTIVE:To examine whether high-frequency heart rate variability, an indirect measure of parasympathetic (vagal) control over variations in heart rate, is associated with immune reactivity to an in vitro inflammatory challenge. Convergent evidence from the animal literature shows that the autonomic nervous system pla...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181576118

    authors: Marsland AL,Gianaros PJ,Prather AA,Jennings JR,Neumann SA,Manuck SB

    更新日期:2007-11-01 00:00:00

  • Differential predictive value of depressive versus anxiety symptoms in the prediction of 8-year mortality after acute coronary syndrome.

    abstract:OBJECTIVE:Both depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity. METHODS:Patients with ACS ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e318268978e

    authors: Doyle F,Conroy R,McGee H

    更新日期:2012-09-01 00:00:00

  • Stressful life events and survival after breast cancer.

    abstract:OBJECTIVE:This study assessed the relation of stressful life events with survival after breast cancer. METHODS:This study was based on women with histologically confirmed, newly diagnosed, localized or regional stage breast cancer first treated in 1 of 11 Quebec City (Canada) hospitals from 1982 through 1984. Among 76...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200103000-00017

    authors: Maunsell E,Brisson J,Mondor M,Verreault R,Deschcnes L

    更新日期:2001-03-01 00:00:00

  • Social stress influences tumor growth.

    abstract::Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated following social and physical stress exposure. Although social isolation following tumor cell transplantation enhanced tumor growth, it appeared that it was the abrupt change in social conditions, rather than the isolation per se which was responsi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198005000-00005

    authors: Sklar LS,Anisman H

    更新日期:1980-05-01 00:00:00

  • Stressed-Out Oral Immunity: A Gateway From Socioeconomic Adversity to Periodontal Disease.

    abstract:OBJECTIVE:It has been suggested that adverse socioeconomic conditions "get under the skin" by eliciting a stress response that can trigger periodontal inflammation. We aimed to a) estimate the extent to which socioeconomic position (SEP) is associated with periodontal disease (PD) and proinflammatory oral immunity, and...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000774

    authors: Gomaa N,Glogauer M,Nicolau B,Tenenbaum H,Siddiqi A,Fine N,Quiñonez C

    更新日期:2020-02-01 00:00:00

  • It's more than sex: exploring the dyadic nature of sleep and implications for health.

    abstract::Sleep is a critical health behavior and one that is typically shared between husbands and wives or romantic partners. However, the science of sleep has traditionally conceptualized and evaluated sleep at the level of the individual. Considering the social context of sleep represents a significant shift in sleep resear...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0b013e3181de7ff8

    authors: Troxel WM

    更新日期:2010-07-01 00:00:00

  • Altruistic social interest behaviors are associated with better mental health.

    abstract:OBJECTIVE:This study investigated whether altruistic social interest behaviors such as engaging in helping others were associated with better physical and mental health in a stratified random sample of 2016 members of the Presbyterian Church throughout the United States. METHODS:Mailed questionnaires evaluated giving ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000079378.39062.d4

    authors: Schwartz C,Meisenhelder JB,Ma Y,Reed G

    更新日期:2003-09-01 00:00:00

  • Testosterone, aggression, physical, and personality dimensions in normal adolescent males.

    abstract::Fifty-eight normal adolescent Swedish boys, aged 16, provided two sets of blood samples for plasma testosterone assays as well as data on a number of personality inventories and rating scales assessing aggression, inpulsiveness, lack of frustration tolerance, extraversion, and anxiety. Physical variables such as puber...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198003000-00003

    authors: Olweus D,Mattsson A,Schalling D,Löw H

    更新日期:1980-03-01 00:00:00

  • Cardiovascular Risk Factors as Differential Predictors of Incident Atypical and Typical Major Depressive Disorder in US Adults.

    abstract:OBJECTIVE:Although the association between major depressive disorder (MDD) and future cardiovascular disease (CVD) is established, less is known about the relationship between CVD risk factors and future depression, and no studies have examined MDD subtypes. Our objective was to determine whether hypertension, tobacco ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000583

    authors: Patel JS,Berntson J,Polanka BM,Stewart JC

    更新日期:2018-07-01 00:00:00

  • Chest pain in patients with cardiac and noncardiac disease.

    abstract:OBJECTIVE:To describe factors influencing chest pain expression in patients with cardiac or noncardiac disease. METHODS:The authors conducted a case presentation and review of literature. RESULTS:Causes of chest pain are diverse. Psychologic factors influence chest pain expression commonly in patients with or without...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.psy.0000146330.80895.77

    authors: Sheps DS,Creed F,Clouse RE

    更新日期:2004-11-01 00:00:00

  • Suppressed anger and blood pressure: the effects of race, sex, social class, obesity, and age.

    abstract::We studied 572 men and women who participated in a blood pressure screening program at a government unemployment office. Before having their blood pressures taken, the subjects completed a brief questionnaire that included two items measuring conflict over anger expression. Information was also obtained on obesity, ra...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198607000-00005

    authors: Dimsdale JE,Pierce C,Schoenfeld D,Brown A,Zusman R,Graham R

    更新日期:1986-07-01 00:00:00

  • Hypnotic relaxation in the treatment of premature labor.

    abstract::Hypnotic relaxation was used as an adjunct to pharmacologic treatment with 39 women hospitalized for premature contractions in pregnancy. The control group received medication alone and consisted of 70 women. Treatment was started at the time of hospitalization and lasted for 3 hr on the average. Patients were also gi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198605000-00005

    authors: Omer H,Friedlander D,Palti Z

    更新日期:1986-05-01 00:00:00

  • Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder.

    abstract::This study was designed to investigate relationships between serum thyroid hormone levels and the severity of posttraumatic stress disorder (PTSD) symptoms in a group of 65 male Vietnam combat veterans who participated as members of cohorts in an elective inpatient treatment program. Thyroid hormone measures included ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199507000-00012

    authors: Wang S,Mason J,Southwick S,Johnson D,Lubin H,Charney D

    更新日期:1995-07-01 00:00:00

  • Sacral neuromodulation for urinary retention caused by sexual abuse.

    abstract:OBJECTIVE:This case report describes the use of sacral neuromodulation to treat urinary retention after sexual abuse. METHODS:Sacral neuromodulation was added to therapeutic regimen of a 38-year-old woman in whom chronic, complete urinary retention developed after psychological and sexual abuse during childhood. RESU...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200105000-00022

    authors: von Heyden B,Steinert R,Bothe HW,Hertle L

    更新日期:2001-05-01 00:00:00

  • Generalized anxiety disorder, major depressive disorder, and their comorbidity as predictors of all-cause and cardiovascular mortality: the Vietnam experience study.

    abstract:OBJECTIVE:To examine whether the 1-year prevalence of major depressive disorder (MDD), generalized anxiety disorder (GAD), and their comorbidity were associated with subsequent all-cause and cardiovascular disease (CVD) mortality during 15 years in Vietnam veterans. METHODS:Participants (N = 4256) were from the Vietna...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31819e6706

    authors: Phillips AC,Batty GD,Gale CR,Deary IJ,Osborn D,MacIntyre K,Carroll D

    更新日期:2009-05-01 00:00:00

  • Effects of age and gender on the relationship between anxiety and coronary artery disease.

    abstract::This study investigated the relationship between anxiety and coronary artery disease (CAD). State (S-ANX) and trait (T-ANX) anxiety were assessed with the State-Trait Personality Inventory (STPI), which was administered to 373 patients (230 males, 143 females) 12 to 18 hr prior to their undergoing coronary arteriograp...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198703000-00002

    authors: Schocken DD,Greene AF,Worden TJ,Harrison EE,Spielberger CD

    更新日期:1987-03-01 00:00:00

  • Stress vulnerability during adolescence: comparison of chronic stressors in adolescent and adult rats.

    abstract:OBJECTIVE:This study investigated the physiological and somatic changes evoked by daily exposure to the same type of stressor (homotypic) or different aversive stressor stimuli (heterotypic) in adolescent and adult rats, with a focus on cardiovascular function. The long-term effects of stress exposure during adolescenc...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000141

    authors: Duarte JO,Cruz FC,Leão RM,Planeta CS,Crestani CC

    更新日期:2015-02-01 00:00:00

  • Blood pressure increases while signing in a deaf population.

    abstract::Recent technologic advances have permitted the observation of rapid and significant increases in blood pressure (BP) during verbal communication. The magnitude of the increase in BP is influenced by rate of speech, audience size, status, affective content, environmental setting, and resting BP. The current study evalu...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198601000-00008

    authors: Malinow KL,Lynch JJ,Foreman PJ,Friedmann E,Thomas SA

    更新日期:1986-01-01 00:00:00