当前位置： SCI文献检索 > CELLULAR IMMUNOLOGY期刊下所有文献 > Immunization of susceptible BALB/c mice against Leishmania braziliensis. II. Use of temperature-sensitive avirulent clones of parasite for vaccination purposes.

Immunization of susceptible BALB/c mice against Leishmania braziliensis. II. Use of temperature-sensitive avirulent clones of parasite for vaccination purposes.

Abstract：

:Avirulent clones of Leishmania braziliensis were produced by treatment of parental parasite stock with the mutagen N-methyl-N'-methyl-N'-nitro-N-nitrosoguanidine and selection for growth at 19 degrees C. These clones have a clear preference for infection and growth in vitro at 19 degrees C rather than the normal 28 degrees C. In addition, they can be used to vaccinate naive mice successfully against growth of the parental parasite clones. Immunity can be adoptively transferred from vaccinated mice by Lyt-1+ cells from immunized animals.

journal_name

Cell Immunol

journal_title

Cellular immunology

authors

Gorczynski RM

doi

10.1016/0008-8749(85)90081-4

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

11-20

issue

1

eissn

0008-8749

issn

1090-2163

pii

0008-8749(85)90081-4

journal_volume

94

pub_type

杂志文章

相关文献

CELLULAR IMMUNOLOGY文献大全
  • Prolonged allogeneic and xenogeneic microchimerism in unmatched primates without immunosuppression by intrathymic implantation of CD34+ donor marrow cells.

    abstract：:Engraftment of stem cell-enriched donor marrow implanted in the thymus of a foreign host might facilitate acceptance of donor-specific organ or tissue grafts. To test this hypothesis, allogeneic and xenogeneic CD34+ marrow cells from unrelated adult male baboons and humans were injected intrathymically in eight infant...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1997.1194

    authors： Allen MD,Weyhrich J,Gaur L,Akimoto H,Hall J,Dalesandro J,Sai S,Thomas R,Nelson KA,Andrews RG

    更新日期：1997-11-01 00:00:00

  • Association of serine protease with the rise of intracellular calcium in cytotoxic T lymphocytes.

    abstract：:The precise role of the granular enzyme A (granzyme A), a serine protease, in the lytic process of cytotoxic T lymphocytes (CTL) is not clear. We have recently constructed a CTL line transfected with the antisense gene of granzyme A (a-GrA). These a-GrA CTL had lower GrA activity as well as decreased lytic activities,...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1996.0300

    authors： Koo GC,Luk Y,Talento A,Wu J,Sirotina A,Fischer PA,Blake JT,Nguyen MP,Parsons W,Poe M

    更新日期：1996-12-15 00:00:00

  • Immediate, long-lasting suppression of autoimmune encephalomyelitis by cell-bound neuroantigen.

    abstract：:When lymphoid cells from rats recovered from experimental autoimmune encephalomyelitis (EAE) were incubated in vitro for 1 hr with myelin basic protein (BP), then washed and transferred along with anti-BP immune serum to naive recipients, those recipients immediately developed a solid, long-lasting resistance to activ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(89)90272-4

    authors： Hugh AR,Simmons RD,Willenborg DO

    更新日期：1989-10-01 00:00:00

  • Regulation of immune responses by E3 ubiquitin ligase Cbl-b.

    abstract：:Casitas B lymphoma-b (Cbl-b), a RING finger E3 ubiquitin ligase, has been identified as a critical regulator of adaptive immune responses. Cbl-b is essential for establishing the threshold for T cell activation and regulating peripheral T cell tolerance through various mechanisms. Intriguingly, recent studies indicate...

    journal_title：Cellular immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.cellimm.2018.11.002

    authors： Tang R,Langdon WY,Zhang J

    更新日期：2019-06-01 00:00:00

  • Lenalidomide down regulates the production of interferon-gamma and the expression of inhibitory cytotoxic receptors of human Natural Killer cells.

    abstract：:Lenalidomide, a daughter molecule of Thalidomide, and IMIDs are immunomodulatory drugs that have been described as having immunomodulatory properties and anti-tumor activity. The effect of Lenalidomide towards Peripheral Blood Mononuclear Cells (PBMC) has been studied and direct effects towards T cells have been descr...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2010.06.003

    authors： Dauguet N,Fournié JJ,Poupot R,Poupot M

    更新日期：2010-01-01 00:00:00

  • IL-12 inhibits apoptosis induced in a human Th1 clone by gp120/CD4 cross-linking and CD3/TCR activation or by IL-2 deprivation.

    abstract：:The aim of our work was to study apoptosis as a possible mechanism of CD4+ lymphocyte depletion in AIDS patients and to test whether IL-12 could limit this phenomenon. As an in vitro model, we used a human IL-2-dependent Th1 clone from an uninfected individual. We found that CD4 cross-linking, obtained either by mouse...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1995.1003

    authors： Radrizzani M,Accornero P,Amidei A,Aiello A,Delia D,Kurrle R,Colombo MP

    更新日期：1995-03-01 00:00:00

  • Anti-Fas antibody induces different types of cell death in the human histiocytic cell line, U937, and the human B cell line, B104: the role of single-strand DNA breaks and poly (ADP-ribosyl)ation in cell death.

    abstract：:We investigated the anti-Fas antibody-induced cell death in two different types of human cell lines, U937 and B104. IFN-gamma increased the surface expression of Fas antigen and susceptibility to anti-Fas Ab-induced cell death of B104 and U937 cells. Anti-Fas Ab-induced death of U937 and B104 cells required neither a ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1994.1016

    authors： Sumimoto S,Ishigami T,Horiguchi Y,Yonehara S,Kanazashi S,Heike T,Katamura K,Mayumi M

    更新日期：1994-01-01 00:00:00

  • DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathway.

    abstract：:Latent Mycobacterium tuberculosis (Mtb) infection (LTBI) is the main clinical manifestation after Mtb exposure. During the latent phase, Mtb retards the attempts of eradication by the host immune system. The dormancy survival regulator (DosR) is held as essential for Mtb persistence. Rv1737c is predominantly expressed...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2019.103947

    authors： Gao X,Wu C,He W,Wang X,Li Y,Wang Y,Jia Y,Yuan R,Li H,Zhang B

    更新日期：2019-10-01 00:00:00

  • Requirement for CD4+ T cells in the gammadelta T cell proliferative response to Daudi Burkitt's lymphoma.

    abstract：:Daudi Burkitt's lymphoma cells stimulate the proliferation of Vgamma2 Vdelta2 T cells in human peripheral blood mononuclear cells (PBMC). Transfection studies have established that the gammadelta T cell receptor is sufficient for recognition of a ligand associated with Daudi cells. Since other studies have demonstrate...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1996.0289

    authors： Burns J,Lobo S,Bartholomew B

    更新日期：1996-11-25 00:00:00

  • Th17 pathway in recent-onset autoimmune diabetes.

    abstract：AIMS:Evaluate the participation of IL-17 pathway in T1D pathogenesis. T helper 17 cells are potent, highly inflammatory cells that produce interleukin 17A (IL-17A), considered a mediator of various immune disorders. However, their role in Type 1 diabetes (T1D) pathogenesis in humans is not totally elucidated. METHODS:...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2017.11.005

    authors： Fores JP,Crisostomo LG,Orii NM,Santos AS,Fukui RT,Matioli SR,de Moraes Vasconcelos D,Silva MERD

    更新日期：2018-02-01 00:00:00

  • The autoimmune mouse MRL/Mp-lpr/lpr contains cells with spontaneous cytotoxic activity against target cells bearing self-determinants.

    abstract：:Spontaneously cytotoxic cells possessing specificity and having a complex pattern of reactivity directed at least partly against self-determinants develop by the age of 10 weeks in the autoimmune mouse strain MRL/Mp-lpr/lpr (MRL-lpr) and by the age of 6 months in C57BL/6-lprl/lpr. Similar effector cells do not develop...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(88)90003-2

    authors： Muraoka S,Miller RG

    更新日期：1988-04-15 00:00:00

  • Biochemical basis of HLA-DR and CR3 modulation on human peripheral blood monocytes by lipopolysaccharide.

    abstract：:The biochemical events leading to enhanced membrane expression of HLA-DR and CR3 by human peripheral blood monocytes (MO) following exposure to bacterial lipopolysaccharide (LPS) were examined. In a previous study we demonstrated that an increase in intracellular calcium was necessary, but not sufficient, for MO to in...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(87)90209-7

    authors： McLeish KR,Wellhausen SR,Dean WL

    更新日期：1987-08-01 00:00:00

  • Requirement for accessory cells in suppression of MOPC-315 IgA secretion by staphylococcal enterotoxin B-induced T-suppressor cells.

    abstract：:Staphylococcal enterotoxin B (SEB) is a potent polyclonal activator of both human and murine T cells. We previously reported data which show that SEB-induced T cells suppress antibody secretion by various mouse plasmacytoma cell lines. This suppression of antibody secretion was found to be both idiotype and isotype no...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(90)90227-i

    authors： Newcomb JR,Lin YS,Rogers TJ

    更新日期：1990-09-01 00:00:00

  • Kinetics of activation antigen expression by in vitro-stimulated human T lymphocytes.

    abstract：:In this study a panel of monoclonal antibodies was used to investigate the kinetics of the appearance of activation-linked surface determinants as well as cytoplasmic and nuclear determinants in human T cells following lectin stimulation. Well known activation markers, such as Ia/DR, transferrin receptor, IL-2 recepto...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(85)90197-2

    authors： Holter W,Majdic O,Liszka K,Stockinger H,Knapp W

    更新日期：1985-02-01 00:00:00

  • Role of different lymphocyte subsets in human anti-viral T cell cultures.

    abstract：:We have systematically studied uncloned human cell lines derived from anti-influenza A virus or anti-Epstein-Barr virus (EBV) bulk cultures, or from cultures highly enriched for CD4+ or CD8+ lymphocytes. The most noteworthy results are the following: (1) Anti-viral bulk cultures consisted of more than 90% of CD8+ cell...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(89)90380-8

    authors： Gomez A,Bourgault I,Gomard E,Picard F,Levy JP

    更新日期：1989-02-01 00:00:00

  • Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo.

    abstract：:In order to track hematopoetic cells of all lineages unambiguously at all stages of development, we have developed C57BL/6 mice that express a transgene coding for green fluorescent protein (GFP) under control of the human ubiquitin C promoter. These mice, called UBI-GFP/BL6, express GFP in all tissues examined, with ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.2001.1895

    authors： Schaefer BC,Schaefer ML,Kappler JW,Marrack P,Kedl RM

    更新日期：2001-12-15 00:00:00

  • Powerful immunosuppression mediated by interleukin 2-activated, nonantigen-specific, or H-2-restricted THY-1+ CD8+ cells.

    abstract：:Normal spleen cells cultured in high or low concentrations of interleukin (IL) 2 for 3 days contain Thy-1+ CD4- CD8+ cells that powerfully suppress primary but not ongoing or active lymphocyte responses. The precursors of these cells are Thy-1+ AGM-1- and are absent or present in greatly diminished numbers in athymic ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(89)90111-1

    authors： Torre-Amione G,Tuetken R,Rowley DA

    更新日期：1989-11-01 00:00:00

  • T cell receptor V beta usage in murine experimental autoimmune thyroiditis.

    abstract：:Mouse thyroglobulin (MTg)-sensitized spleen cells activated in vitro with MTg induced experimental autoimmune thyroiditis (EAT) in which the thyroid infiltrate consists primarily of mononuclear cells (MNC) (lymphocytic EAT). MTg-sensitized spleen cells cultured with MTg together with anti-IL2R antibody induce a granul...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1996.0208

    authors： McMurray RW,Hoffman RW,Tang H,Braley-Mullen H

    更新日期：1996-08-25 00:00:00

  • Immunological properties of umbilical cord blood-derived mesenchymal stromal cells.

    abstract：:Mesenchymal stromal cells (MSCs) are promising candidates for developing cell therapies for intractable diseases. To assess the feasibility of transplantation with human umbilical cord blood (hUCB)-derived MSCs, we analyzed the ability of these cells to function as alloantigen-presenting cells (APC) in vitro. hUCB-MSC...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2008.04.003

    authors： Oh W,Kim DS,Yang YS,Lee JK

    更新日期：2008-02-01 00:00:00

  • NFκB and TGFβ contribute to the expression of PTPN3 in activated human lymphocytes.

    abstract：:We previously reported that protein tyrosine phosphatase non-receptor type 3 (PTPN3), which is upregulated in activated lymphocytes, acts as an immune checkpoint. However, the mechanism by which PTPN3 expression is enhanced in activated lymphocytes is unknown. In this study, we analyzed the mechanism of PTPN3 expressi...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2020.104237

    authors： Nakayama K,Onishi H,Fujimura A,Imaizumi A,Kawamoto M,Oyama Y,Ichimiya S,Koga S,Fujimoto Y,Nakashima K,Nakamura M

    更新日期：2020-12-01 00:00:00

  • Allotype suppression in the chicken. V. Abnormal isotype ratios of chronically suppressed IgM and IgG allotypes.

    abstract：:Chronic allotype suppression was generated in M-1 (C mu), G-1 (C gamma) heterozygous B14 line chickens either by embryonal injection or by maternal transfer of anti-M-1b allotype antibodies. Using a sensitive radioimmunoassay to detect the suppressed IgM-1b, a striking disparity was observed between the degree of supp...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(84)90240-5

    authors： Ratcliffe MJ

    更新日期：1984-01-01 00:00:00

  • Impact of polyunsaturated fatty acids on cytoskeletal linkage of L-selectin.

    abstract：:Polyunsaturated fatty acid [omega-3 polyunsaturated fatty acids (omega-3PUFAs)] incorporation into cell membranes has been shown to have potent anti-inflammatory activity, though the mechanisms involved are only partially characterized. Here, we show that PUFA enrichment of T cell membranes decreased the overall expre...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2004.04.004

    authors： Leid JG,Jutila MA

    更新日期：2004-04-01 00:00:00

  • Maternal HEL immunization has no lasting effects on the immune response of offspring to immunization with hen egg-white lysozyme.

    abstract：:The effect of prior maternal immunization on the murine offspring response to subsequent immunization with hen egg-white lysozyme was examined. Adult female A/J mice were immunized with 100 micrograms HEL-CFA intraperitoneally 10-27 weeks before conception. The offspring of these experimental female mice were then imm...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1993.1123

    authors： Jelonek MT,Brust JL,Song CH,Calandra GB,Miller A,Sercarz EE,Keller MA

    更新日期：1993-05-01 00:00:00

  • Induction of target cell apoptosis by channel catfish cytotoxic cells.

    abstract：:This study examines cytotoxic mechanisms used by channel catfish peripheral blood-derived effector cells. Transmission electron microscopy (TEM), coupled with [(3)H]thymidine DNA fragmentation (JAM) and terminal deoxynucleotidyl nick-end labeling (TUNEL) assays, provided the first evidence that catfish peripheral bloo...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1999.1523

    authors： Hogan RJ,Taylor WR,Cuchens MA,Naftel JP,Clem LW,Miller NW,Chinchar VG

    更新日期：1999-08-01 00:00:00

  • Thymic alterations in Plasmodium berghei-infected mice.

    abstract：:The primary function of the thymus is to develop immature T-cells into cells that further in the periphery will be able to carry out immune functions. The Literature has shown that thymus can be a target for many pathogens and severe structural alterations take place in this organ during infectious diseases. Here, we ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2008.06.001

    authors： Andrade CF,Gameiro J,Nagib PR,Carvalho BO,Talaisys RL,Costa FT,Verinaud L

    更新日期：2008-05-01 00:00:00

  • Exposure to chemokines during maturation modulates antigen presenting cell function of mature macrophages.

    abstract：:Macrophages generated with macrophage-colony stimulating factor (M-CSF) are defective in antigen presenting cell (APC) function, although they do express major histocompatibility (MHC) class II molecules, numerous accessory molecules, and intercellular adhesion molecules. In the present study, we show evidence that th...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2005.04.017

    authors： Lee JK,Kim JK,Lee YR,Kim HS,Im SA,Kim K,Lee CK

    更新日期：2005-03-01 00:00:00

  • Interleukin-12 is expressed by infiltrating macrophages and synovial lining cells in rheumatoid arthritis and osteoarthritis.

    abstract：:TH1 cytokines have recently been detected in rheumatoid arthritis (RA) and osteoarthritis (OA). For this reason we studied the TH-1-promoting cytokine IL-12 in synovial membranes from patients with RA and OA. IL-12 transcripts and protein were analyzed by reverse transcriptase-polymerase chain reaction (PCR) and immun...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1998.1363

    authors： Sakkas LI,Johanson NA,Scanzello CR,Platsoucas CD

    更新日期：1998-09-15 00:00:00

  • Monocyte-derived macrophage and alveolar macrophage fibronectin production and cathepsin D activity.

    abstract：:Alveolar macrophages are thought to play an important role in ongoing tissue breakdown and repair processes in the normal lung. The secretion and regulation of cathepsin D (important for the final breakdown of collagen) and fibronectin (involved in the healing process) in human peripheral blood monocytes (PBM) and pul...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(90)90320-q

    authors： Rossman MD,Maida BT,Douglas SD

    更新日期：1990-04-01 00:00:00

  • IFN-γ-induced BST2 mediates monocyte adhesion to human endothelial cells.

    abstract：:BST2 is a type II transmembrane protein that had been initially identified as a surface molecule expressed on terminally differentiated B cells. Here, we characterize the expression of BST2 in human endothelial cells, HUVECs. IFN-γ, among various inflammatory stimuli, dramatically upregulates BST2 expression in HUVECs...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2010.10.011

    authors： Yoo H,Park SH,Ye SK,Kim M

    更新日期：2011-01-01 00:00:00

  • Effects of ultraviolet-B irradiation on human LAK and NK cytotoxic activity.

    abstract：:In vitro ultraviolet-B (UVB) irradiation of murine and rodent bone marrow cells prevents GVHD without compromising engraftment while inducing tolerance to donor-type allografts. In anticipation of clinical trials of UVB-modified bone marrow grafts, we studied the in vitro effects of UVB irradiation (50-300 J/m2) on hu...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1995.1202

    authors： Yaron I,Zakheim AR,Oluwole SF,Hardy MA

    更新日期：1995-10-15 00:00:00