Abstract：
:Epidemiological evidence strongly indicates that Helicobacter pylori infection is an essential factor for the development of most non-cardia gastric cancer. Furthermore, the identification of an effective animal model and a plausible biological hypothesis provide further compelling evidence for its pathogenic role. Nevertheless, it will be some years before prospective studies in humans are able to confirm cause and effect beyond any doubt. In the meantime sceptics point out that the prevalence of Helicobacter pylori in different countries do not always correlate with the incidence of gastric cancer. It is unclear why patients with duodenal ulcer (who are almost invariably infected) are protected from the disease. Cancer often develops in patients from whom Helicobacter disappeared from the stomach years previously. This paper discusses the relationship between Helicobacter pylori infection, the development of gastritis and its evolution to non-cardia gastric cancer. It also addresses possible reasons why the incidence of gastric cancer does not always mirror the prevalence of Helicobacter infection throughout the world and why patients with duodenal ulcer may be protected from developing gastric cancer.
journal_name
Adv Med Scijournal_title
Advances in medical sciencesauthors
Axon ATsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
55-60eissn
1896-1126issn
1898-4002journal_volume
52pub_type
杂志文章,评审abstract：:Lung cancer causes an estimated 1.6 million deaths each year, being the leading cause of cancer-related deaths in the world. Late diagnosis and, in some cases, the high aggressiveness of the tumour result in low overall five-year survival rates of 12% among men and 7% among women. The cure is most likely in early-stag...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2017.12.002
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Genetic variability of hepatitis C virus (HCV) is considered to be an important factor defining viral pathogenesis, persistence and resistance to treatment. The aim of the present study was to characterize HCV genetic heterogeneity within a hypervariable region 1 (HVR-1) before and during the early period of pe...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0024-8
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Obstructive sleep apnea increases the risk of cardiovascular diseases. Alternations in prostacyclin and thromboxane concentrations and balance could constitute one of mechanisms linking sleep apnea and cardiovascular events. Thus we aimed to assess the concentrations of 6-keto-prostaglandin F1α (6-keto-PGF1α) (...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.12.001
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:Solid tumors modulate their environment to keep non-malignant stromal cells in a tumor-promoting state. The main cells in the stroma of epithelial derived tumors are cancer associated fibroblasts (CAF) that are critical to tumorigenesis and angiogenesis. CAFs also supply the tumor cells with growth factors and ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.04.006
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To evaluate intravascular xenotransplantation of macroencapsulated pancreatic islet cells in the process of the treatment of diabetes mellitus type 1 without immunosuppressive therapy. MATERIAL AND METHODS:Xenogenic intravascular transplantation was performed in 19 patients with diabetes mellitus (type 1) havi...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-008-0045-5
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the influence of selective agonists of the retinoid receptor X (RXR) and the retinoid acid receptor (RAR) on bone metabolism in rats. METHODS:Thirty six male Wistar rats were divided into three groups: receiving bexarotene, or tazarotene, or to control group. Serum ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.09.001
更新日期：2016-03-01 00:00:00
abstract：:The increasing demand in studying cellular functions in cultured cells under various levels of oxygen and hydrogen peroxide (H2O2) is only partly fulfilled by conventional approaches such as hypoxia chambers, bolus additions of H2O2 or redox-cycling drugs. This article describes the recently developed enzymatic GOX/CA...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-009-0042-3
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:The question of whether or not non-sporadic breast malignancies have different immunohistochemical features than sporadic malignancies has not been investigated previously. Consequently, the purpose of this study was to compare the expression of E-cadherin (EC) in breast cancer patients with positive and negati...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-008-0007-y
更新日期：2008-01-01 00:00:00
abstract：:In liver surgery, accurate assessments of liver resection volume and anatomical variation are mandatory for preoperative planning of safe curative hepatectomy. In living donor liver transplantation (LDLT), estimation of hepatic venous drainage is important to avoid liver graft and donor residual liver congestion. This...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:Defining the level of protective factors in saliva of patients suffering from decompensated type 2 diabetes. MATERIAL AND METHODS:50 Patients with diagnosis of decompensated type 2 diabetes, including 32 women and 18 men at the age of 57.9±9.2 years. The control group consisted of 50 people among whom there we...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2016.06.005
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:In the literature, the manifestations of gastric cancer have been described based on all patients. In recent times, interest has focused on the subgroup of young patients. In the following analysis, the subgroup of young patients (< 50y) is compared with an older reference group (≥ 50y). MATERIAL AND METHODS:B...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0052-4
更新日期：2012-01-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) is a problem frequently occurring among physically and intellectually disabled individuals. In this group of patients GERD is often overlooked, since the symptoms are usually non-specific. We present two cases of disabled children, who developed complications of GERD in the form ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:Cerebral metastases develop in 10-30% of patients with breast cancer (BC) and in around 3.3 to 4% of patients with ovarian cancer (OC). The aim of the multicenter study is to investigate the correlation between the expression of estrogen alpha receptors (ERα), progesterone receptors (PR), human epidermal growth...
journal_title：Advances in medical sciences
pub_type： 杂志文章,多中心研究
doi：10.1016/j.advms.2018.12.007
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:Glaucoma is one of the most important reason causes of the blindness, associated with retinal ganglion cells (RGC) death. This process is not fully understood, however apoptosis due to hypoxia is one of the most important processes leading to RGC death. Glaucomatous optic neuropathy is characterized by remodeli...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.07.007
更新日期：2016-03-01 00:00:00
abstract：:Vascular calcification (VC) is highly prevalent in patients with chronic kidney disease (CKD) and is strongly associated with cardiovascular mortality and morbidity. Accumulating evidence over the past decade has challenged the hypothesis of close interaction between bone and VC what raises the possibility of a common...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2016.08.001
更新日期：2017-03-01 00:00:00
abstract：PURPOSE:Behaviour of the vein thrombus is determined by the activity ratio of coagulation factors to factors of fibrinolytic system. The aim of the study is to evaluate activity of some coagulation and fibrinolytic factors in the vein thrombus. MATERIAL AND METHODS:The activity of platelets aggregating factors, tissue...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:Methylenetetrahydrofolate reductase (MTHFR) is an enzyme involved in endothelial nitric oxide synthase (eNOS) coupling and homocysteine metabolism. The rs1801133 polymorphism of the MTHFR gene affects risk of coronary artery disease. We assessed its influence on 5-year survival of patients with ST-elevation acu...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0010-1
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:The aim of the study was to evaluate factors related to bone formation and resorption in Polish children and adolescents with cystic fibrosis and to examine the effect of nutritional status, biochemical parameters and clinical status on bone mineral density. MATERIALS AND METHODS:The study group consisted of 1...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.05.002
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:Accumulating evidence has linked long noncoding RNAs (lncRNAs) to autoimmune and inflammatory disorders. This study aimed to detect the expression levels of five lncRNAs (lnc0640, lnc3643, lnc5150, lnc7514 and lncagf) in peripheral blood mononuclear cells (PBMCs) of patients with systemic lupus erythematosus (S...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2019.08.002
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:The concentration of nucleic acids that undergo apoptosis (ssDNA) determines the actual activity of programmed cell death. ssDNA concentrations in liver tissue of patients with chronic HBV, HCV and HCV and HIV infections were assessed. The concentration of this nucleic acid was analyzed in relation to the conce...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:We analyzed the usefulness and prognostic value of intraoperative monitoring for identification of the oculomotor (III) and the abducens (VI) nerve in patients with cavernous sinus meningiomas. MATERIAL/METHODS:43 patients diagnosed with cavernous sinus meningiomas were divided according to their topography. F...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2014.08.009
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:Non-alcoholic fatty liver disease (NAFLD) is increasingly being recognized in the pediatric population, therefore, the search for non-invasive parameters to predict progression of NAFLD is of great interest. The aim of this study was to assess serum concentration of sCD36 in children with obesity and to determi...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2020.11.004
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Molecular features of non-small cell lung cancer (NSCLC) in never-smokers are not well recognized. We assessed the expression of genes potentially related to lung cancer etiology in smoking vs. never-smoking NSCLC patients. METHODS:We assayed frozen tumor samples from surgically resected 31 never-smoking and 5...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/ams-2013-0025
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:Arterial hypertension (aHT) is the leading risk factor for morbidity and mortality worldwide. Blood pressure (BP) deviation at rest is well defined and accompanies risk for cardiovascular events and cardiovascular mortality. A growing body of evidence emphasises that an exaggerated blood pressure response (EBPR...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2016.11.010
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:The aim of this study was to determine the antimicrobial resistance and the occurrence of virulence determinants among glycopeptide-resistant enterococci (GRE) isolated in 2007-2009 from patients hospitalized in southwestern Poland. MATERIAL AND METHODS:The minimal inhibitory concentrations (MICs) of antibioti...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-011-0022-2
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:The aim of the work was to use and to evaluate the usefulness of the slow variable magnetic fields to aid the treatment of the teeth chosen for extraction. The marginal paradontium of periapical bone of teeth was in a state of extensive destruction. The teeth were chosen for extraction. MATERIAL AND METHODS:13...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Adhesive molecules are responsible for the cell-cell interaction and the surrounding intercellular environment creating normal tissue architecture. The role of adhesion proteins in cancer refers to angiogenesis, loss of tissue continuity, and deprivation of intercellular contact with the extracellular matrix, promotin...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2019.08.003
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To assess the serum fetuin A concentration as a potential marker of subclinical atherosclerosis in obese children with NAFLD. MATERIAL/METHODS:A prospective analysis of 45 obese children initially diagnosed with liver pathology (elevated serum ALT activity and/or ultrasonographic liver brightness and/or hepato...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2013.08.003
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:The aim of the study was to establish whether preoperative serum levels of HE4 and CA125 could be a good predictor for lymphadenectomy in the early stage of endometrioid adenocarcinoma of the uterus. MATERIAL AND METHODS:Preoperative serum HE4 and CA125 were measured in 78 postmenopausal patients treated surgi...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.07.010
更新日期：2016-03-01 00:00:00
abstract：:Autoimmune pancreatitis (AIP) is a particular type of pancreatitis that is thought to have an autoimmune etiology. Before therapy for AIP is begun, accurate diagnosis of AIP is necessary. It is important to distinguish AIP from pancreatic cancer. Since there is currently no diagnostic serological marker for AIP, AIP s...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.2478/v10039-008-0033-9
更新日期：2008-01-01 00:00:00
