Immunochemical studies on the differential binding properties of two monoclonal antibodies reacting with Tn red cells.

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：:A 24-year-old, blood-group O Polynesian woman with multiple red blood cell antibodies received a group A, HLA-compatible, sex-matched bone marrow transplantation as treatment for severe aplastic anemia. High retransplantation titers of ABO isohemagglutinins were successfully reduced by repeated plasmaphereses. Despite...

journal_title：Transfusion

authors： Ockelford PA,Hill RS,Nelson L,Blacklock HA,Woodfield DG,Matthews JR

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

journal_title：Transfusion

authors： Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

更新日期：2008-02-01 00:00:00

abstract：:Seven hundred and sixty-three blood donors previously typed for HLA-A and B antigens were asked to consider donating bone marrow to unrelated patients for whom no HLA-matched sibling was available. Eighty-eight percent (668) indicated willingness to donate marrow, and of these, 615 (81%) participated in testing and 53...

journal_title：Transfusion

authors： McElligott MC,Menitove JE,Aster RH

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Maternal D alloimmunization detected in early gestation requires aggressive intervention to prevent severe fetal anemia. An intrauterine transfusion (IUT) is indicated to prevent fetal death once severe fetal anemia has been detected, but is not without risk. Protocols combining therapeutic plasma exchange (...

journal_title：Transfusion

authors： Bellone M,Boctor FN

更新日期：2014-08-01 00:00:00

abstract：:Fourteen Jk(a-b-) persons were detected by testing 638,460 Osaka blood donors with an automated 2 M urea technique. Two of these 14 Jk(a-b-) samples were quite different from the hitherto reported Jk(a-b-) phenotype, and a family study showed that the mode of the inheritance was dominant. The red cell membranes of the...

journal_title：Transfusion

authors： Okubo Y,Yamaguchi H,Nagao N,Tomita T,Seno T,Tanaka M

更新日期：1986-05-01 00:00:00

abstract：:Red cells from a Mexican blood donor had depressed H, IF, ID, i, Sda, Sdx, D, LW, Dib, Vel and JMH antigens. A wide range of other blood group antigens had normal activity. The unusual red cell phenotype may be caused by a membrane anomaly that alters orientation of certain cell surface components. The specificities o...

journal_title：Transfusion

authors： Biro V,Garratty G,Johnson CL,Marsh WL

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Hypericin is a potent virucidal agent with activity against a broad range of enveloped viruses and retroviruses. The effective virucidal activity emanates from a combination of photodynamic and lipophilic properties. Hypericin binds cell membranes (and, by inference, virus membranes) and crosslinks virus cap...

journal_title：Transfusion

authors： Lavie G,Mazur Y,Lavie D,Prince AM,Pascual D,Liebes L,Levin B,Meruelo D

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：:Primers based on the nucleotide sequence of the virF gene in the pYV plasmid and the chromosomal ail gene were used in polymerase chain reaction (PCR) amplifications to directly identify Yersinia enterocolitica in blood. Approximately 500 bacteria seeded into 100 microL of blood can be extracted and amplified by PCR t...

journal_title：Transfusion

authors： Feng P,Keasler SP,Hill WE

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:During the use of commercial red cell (RBC) acid-elution kits for adsorption and elution (adsorption/elution) studies with anti-D, unexpected reactive eluates (anti-D) were obtained from D- RBCs. Such results were not obtained with a parallel xylene method or, historically, with heat and ether methods. STUD...

journal_title：Transfusion

authors： Leger RM,Arndt PA,Ciesielski DJ,Garratty G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Cellular therapies using engineered T cells, haploidentical transplants, and autologous gene therapy are increasing. Specified CD3+ or high CD34+ doses are typically required for subsequent manufacturing, manipulation, or CD34+ selection. Simple, practical, and reliable lymphocyte and hematopoietic progenito...

journal_title：Transfusion

authors： Yoon EJ,Zhang J,Weinberg RS,Brochstein JA,Nandi V,Sachais BS,Shi PA

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Changes within the ABO system are regularly observed phenomena in allogeneic bone marrow transplantation (BMT) and peripheral blood progenitor cell transplantation (PBPCT). Major ABO mismatch can lead to different clinical problems including acute hemolysis after infusion of the allograft, delay of red blood...

journal_title：Transfusion

authors： Scholl S,Klink A,Mügge LO,Schilling K,Höffken K,Sayer HG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Storage of blood units (for 35-42 days, depending on the preservative solution) has been reported to induce changes (e.g., reduction of sialic acid level) in red cells that are expected to alter their aggregability. STUDY DESIGN AND METHODS:The aggregability of stored red cells was monitored in their autolo...

journal_title：Transfusion

authors： Hovav T,Yedgar S,Manny N,Barshtein G

更新日期：1999-03-01 00:00:00

abstract：:A family is described in which two members of the second generation are of the phenotype LW3. In the course of the investigation the mother of the LW3 propositus was at first believed to be phenotypically LW3 as well. Eventually, it was shown that she is, in fact, phenotypically LW2 but that her R-1 (no D), LWlw, geno...

journal_title：Transfusion

authors： Behzad O,Pothiawala M,Rolih SD,Issitt PD,Lee CL

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Full siblings were compared with half-siblings to observe how well the two relationships could be distinguished by informative tests. STUDY AND DESIGN METHODS: Parentage analysis ascertained 25 pairs of full siblings and 25 pairs of half-siblings. The pairs were then examined for the sharing of alleles at th...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA

更新日期：2000-01-01 00:00:00

abstract：:The possible beneficial role of white cells (WBCs) in donor blood has been investigated with respect to their capacity to remove bacteria. Preparations of buffy coat and whole blood, containing as well as reduced of WBCs, were inoculated with Staphylococcus epidermidis, S. aureus, Escherichia coli, Pseudomonas aerugin...

journal_title：Transfusion

authors： Högman CF,Gong J,Eriksson L,Hambraeus A,Johansson CS

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Specific subsets of peripheral blood WBCs are reservoirs for infectious agents, such as CMV and EBV, and can serve as vectors for transfusion transmission of these agents. While filter WBC reduction has been used to prevent transfusion transmission of infections, its effectiveness has not been documented for...

journal_title：Transfusion

authors： Roback JD,Bray RA,Hillyer CD

更新日期：2000-05-01 00:00:00

abstract：:Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their...

journal_title：Transfusion

authors： Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:There is growing interest in radio frequency identification (RFID) technology application for tracking blood products to achieve higher productivity and safety in the transfusion medicine supply chain. We have conducted a limited study to assess the temperature and biological effects of 13.56 MHz RF radiatio...

journal_title：Transfusion

authors： Davis R,Gottschall J,Gutierrez A,Hohberger C,Veeramani D,Holcombe J

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Infectious events have been reported as major environmental triggers of thrombotic thrombocytopenic purpura (TTP). We detail here the potential association between infections and TTP. STUDY DESIGN AND METHODS:We recruited randomly and prospectively a cohort of 280 consecutive TTP patients during a 9-year pe...

journal_title：Transfusion

authors： Morgand M,Buffet M,Busson M,Loiseau P,Malot S,Amokrane K,Fortier C,London J,Bonmarchand G,Wynckel A,Provôt F,Poullin P,Vanhille P,Presne C,Bordessoule D,Girault S,Delmas Y,Hamidou M,Mousson C,Vigneau C,Lautrette A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Blood collection centers are charged with creating donor educational materials (DnEM) that are easily understood across all prospective donor populations, while addressing mandates and recommendations from regulatory agencies and professional standard setting organizations. Donors must have sufficient inform...

journal_title：Transfusion

authors： Wehrli G,Rossmann SN,Waxman DA,Katz LM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A quality monitoring program (QMP) for platelet concentrates (PCs) was implemented at Canadian Blood Services (CBS) to improve standards and to better understand platelet (PLT) products by supplementing routine quality control (QC). STUDY DESIGN AND METHODS:Annual surveys of PCs from CBS production sites we...

journal_title：Transfusion

authors： Levin E,Jenkins C,Culibrk B,Gyöngyössy-Issa MI,Serrano K,Devine DV

更新日期：2012-04-01 00:00:00

abstract：:With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

journal_title：Transfusion

authors： Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:The ABO blood group is a major determinant in living donor kidney transplantation since AB antigens are expressed on renal tissue. Little attention has been directed to the ABH-secretor status of the donor kidney. As renal tissue is capable of secreting soluble ABH antigens in secretors, we examined the infl...

journal_title：Transfusion

authors： Drexler B,Holbro A,Sigle J,Gassner C,Frey BM,Schaub S,Amico P,Plattner A,Infanti L,Menter T,Mihatsch MJ,Stern M,Buser A,Dickenmann M

更新日期：2016-09-01 00:00:00

abstract：:With the advent of remote damage control resuscitation and far-forward surgery, a renewed emphasis has been placed on examining a variety of pharmacologic adjuncts to controlling blood loss before definitive operative intervention. In this paper, the authors review the current state of the art for tranexamic acid (TXA...

journal_title：Transfusion

authors： Rappold JF,Pusateri AE

更新日期：2013-01-01 00:00:00

abstract：:The use of the direct manual hexadimethrine bromide (Polybrene) test (DPT) in the investigation of patients for autoimmune hemolytic anemia (AIHA) was evaluated. Seventy-nine blood samples from 68 patients were tested. A direct antiglobulin test (DAT) using monospecific reagents and the DPT were performed, and a conce...

journal_title：Transfusion

authors： Owen I,Hows J

更新日期：1990-11-01 00:00:00

abstract：:Critically ill neonatal infants receive frequent small-volume red cell (RBC) transfusions for replacement of blood drawn for laboratory analysis or for treatment of symptomatic anemia secondary to underlying medical conditions and/or a relative bleeding diathesis. Retrospective review of transfusion practice in a hosp...

journal_title：Transfusion

authors： Cook S,Gunter J,Wissel M

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV-1 to -4), mosquito-borne flaviviruses with increasing incidence, and expanding global distributions. Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV. METHO...

journal_title：Transfusion

authors： Linnen JM,Vinelli E,Sabino EC,Tobler LH,Hyland C,Lee TH,Kolk DP,Broulik AS,Collins CS,Lanciotti RS,Busch MP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) processing with hydroxyethyl starch (HES) is the most common protocol in the cord blood banks. The quality of UCB volume reduction was guaranteed by minimum manipulation of cord blood samples in the closed system. This study aimed to analyze and compare cell recovery and viability ...

journal_title：Transfusion

authors： Souri M,Nikougoftar Zarif M,Rasouli M,Golzadeh K,Nakhlestani Hagh M,Ezzati N,Atarodi K

更新日期：2017-11-01 00:00:00