White cells protect donor blood against bacterial contamination.

abstract：BACKGROUND:The majority of reports on transfusion reactions address adult patients. Less is known about the types, incidence, and other clinical details of transfusion reactions in pediatric populations. Furthermore, to our knowledge, there have been no previous reports directly comparing these aspects between adults a...

journal_title：Transfusion

authors： Oakley FD,Woods M,Arnold S,Young PP

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Novel gel centrifugation test (GCT) cards were evaluated with respect to their ability to estimate the quantity of IgG on RBCs and the determination of the IgG subclasses IgG1 and IgG3. STUDY DESIGN AND METHODS:In 65 patients with a positive DAT, the amount of IgG-gamma-, IgG1, and IgG3 on RBCs was examined...

journal_title：Transfusion

authors： Lynen R,Krone O,Legler TJ,Köhler M,Mayr WR

更新日期：2002-05-01 00:00:00

abstract：:In this study we tested the seeds of uncultivated plants for lectin activity. Extracts prepared from the seeds of 167 forb species were tested against human red cell samples. Extracts of 54 species agglutinated unmodified or enzyme-modified red cells. In nine species, the hemagglutinating lectin activity could be neut...

journal_title：Transfusion

authors： Hardman JT,Beck ML,Owensby CE

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Bacterial contamination or platelet (PLT) metabolism can change the pH of stored PLT concentrates (PCs). Measurement of pH for quality control is currently done on a limited basis. An easy noninvasive method was developed to obtain sequential pH measurements over time, without risking contamination and/or co...

journal_title：Transfusion

authors： Barker LM,Nanassy OZ,Reed MW,Geelhood SJ,Pfalzgraf RD,Cangelosi GA,De Korte D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Allogeneic transfusion can result in alloimmunization, leading to platelet (PLT) refractoriness and rejection of solid organ transplants. Previously we demonstrated that pathogen reduction using UV light and riboflavin (UV + R) eliminates the immunogenicity of white blood cells (WBCs) in vitro, blocks alloim...

journal_title：Transfusion

authors： Muench MO,Heitman JW,Inglis H,Fomin ME,Marschner S,Goodrich RP,Norris PJ,Jackman RP

更新日期：2016-06-01 00:00:00

abstract：:The research process is a balance between the inherent risks of new discoveries and the risks of research participant safety. Conflicts of interest, inherent to the research process, as well as those introduced by emerging cellular therapies, have the potential to compromise safety. The relationship of trust between t...

journal_title：Transfusion

authors： Yim R

更新日期：2005-10-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:All studied photosensitizers for virus inactivation impair RBCs. To reduce damage to the RBCs without affecting virucidal activity, selective protection of the RBCs is necessary. The ability of the band 3 ligand, dipyridamole, to react with singlet oxygen and to increase the selectivity of photosterilization...

journal_title：Transfusion

authors： vanSteveninck J,Trannoy LL,Besselink GA,Dubbelman TM,Brand A,de Korte D,Verhoeven AJ,Lagerberg JW

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...

journal_title：Transfusion

authors： Meledeo MA,Peltier GC,McIntosh CS,Corley JB,Bynum JA,Cap AP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Acute trauma coagulopathy (ATC) after military trauma has not been comprehensively studied. ATC is defined as a prolonged prothrombin time ratio (PTr) or reduced clot amplitude (A5) in viscoelastic testing. Compared to civilian trauma, military trauma has more injuries from explosions and gunshot wounds (GSW...

journal_title：Transfusion

authors： Woolley T,Gwyther R,Parmar K,Kirkman E,Watts S,Midwinter M,Lucca JD,Hunt BJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS:In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and ...

journal_title：Transfusion

authors： Reiher VSA,Hönger G,Infanti L,Passweg JR,Hösli I,Frey BM,Gassner C,Meyer S,Buser AS,Holbro A,Schaub S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Increased zinc protoporphyrin (ZPP) levels can indicate iron deficiency and may be predictive for low hemoglobin (Hb) deferral in blood donors. Prediction models for Hb deferral in whole blood donors have already been developed. In this study, we examined if addition of ZPP to these prediction models improve...

journal_title：Transfusion

authors： Baart AM,de Kort WL,Moons KG,Atsma F,Vergouwe Y

更新日期：2013-08-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

journal_title：Transfusion

authors： King MJ,Parsons SF,Wu AM,Jones N

更新日期：1991-02-01 00:00:00

abstract：:After immunization with native human red cells and red cells infected with Plasmodium falciparum, mouse splenocytes were fused with a myeloma cell line to obtain hybridomas. Among the antibodies specific for blood group antigens, four antibodies (iB3C4, F12, MR432, and iB4) directed against epitopes related to the Rh ...

journal_title：Transfusion

authors： Rouger P,Edelman L

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Low-titer group O whole blood (LTOWB) is increasingly being used in the civilian trauma setting, although there is a risk of hemolysis. This study evaluated the impact on hemolytic markers following the transfusion of 4 or more units of uncrossmatched LTOWB. METHODS:Civilian adult trauma patients who receiv...

journal_title：Transfusion

authors： Harrold IM,Seheult JN,Alarcon LH,Corcos A,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2020-06-01 00:00:00

abstract：:Twenty-five leukaphereses were done by the Haemonetics system using citrated Dextran 75 in normal saline as anticoagulant, and were compared with a much larger series using hydroxyethyl starch (HES) with and without steroid premedication. The granulocyte and platelet yields were only minimally different between the tw...

journal_title：Transfusion

authors： Huestis DW

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Hemolytic disease of the fetus and newborn (HDFN) is a severe disease, resulting from maternal red cell (RBC) alloantibodies directed against fetal RBCs. The effect of a first-trimester antibody screening program on the timely detection of HDFN caused by antibodies other than anti-D was evaluated. STUDY DES...

journal_title：Transfusion

authors： Koelewijn JM,Vrijkotte TG,van der Schoot CE,Bonsel GJ,de Haas M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Transfusion of bacterially contaminated platelet concentrates (PCs) can result in serious health consequences for the affected patient. Before being released from blood banking facilities, PCs are routinely screened for bacterial contamination by culture-based tests. However, culture-based PC screening metho...

journal_title：Transfusion

authors： Zweitzig DR,Riccardello NM,Pester JM,Jeanmonod R,Kopnitsky MJ,O'Hara SM

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:A sample mix-up occurred in a tissue procurement laboratory in which aliquots of serum from two tissue donors were accidentally mislabeled. The clues to the apparent mixup involved discrepant Hepatitis C test results. In an attempt to resolve the apparent mix up, DNA typing was performed using serum samples ...

journal_title：Transfusion

authors： Allen RW,Pritchard JK

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Intracellular glutathione declines progressively in platelet concentrates stored for transfusion, but little is known about the nature of this process. STUDY DESIGN AND METHODS:Acivicin, an irreversible inhibitor of gamma-glutamyl transpeptidase, was used to determine the fate of glutathione lost from plate...

journal_title：Transfusion

authors： Burch PT,Aman M,Burch JW

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Chronic red blood cell (RBC) transfusion therapy (CTT) is an integral component of the management of severe sickle cell disease (SCD) and can prevent complications, such as stroke. RBC units can be administered via simple transfusion or exchange transfusion, and erythrocytapheresis (automated RBC exchange tr...

journal_title：Transfusion

authors： Kelly S,Quirolo K,Marsh A,Neumayr L,Garcia A,Custer B

更新日期：2016-11-01 00:00:00

abstract：:Anti-D sensitized red cells were converted to stroma, either by digitonin or hypotonic lysis, and eluates prepared by the modified rapid acid-stromal method. SDS-PAGE and both rocket- and crossed-immunoelectrophoresis showed that, of the total protein content of the eluates, 11 to 25 percent was IgG, 18 to 45 percent ...

journal_title：Transfusion

authors： Rearden A,Chiu P,Elmajian D

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

journal_title：Transfusion

authors： Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

更新日期：2018-03-01 00:00:00

abstract：:Baboons were bled one-third of their blood volume and then transfused with an equivalent volume of compatible donor red blood cells with 160 per cent of normal 2,3-diphosphoglycerate (2,3-DPG) levels and improved capacity to release oxygen to tissue. The mixture of baboon donor-recipient red blood cells in the circula...

journal_title：Transfusion

authors： Zaroulis CG,Pivacek LE,Lowrie GB,Valeri CR

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Thromboelastography (TEG) is widely used in hospitals but less commonly in blood banks for evaluation of platelet (PLT) concentrates (PCs). A TEG-PC assay for testing fresh or stored PLTs must reflect the quality of the PLTs. The added value could be measurement of donor-dependent PLT quality. STUDY DESIGN ...

journal_title：Transfusion

authors： Bontekoe IJ,van der Meer PF,de Korte D

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...

journal_title：Transfusion

authors： Kresnik PK,Krasna M,Rozman P,Vrtovec B,Malicev E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:It is not known whether increasing the dose of filgrastim after mobilizing chemotherapy improves collection of peripheral blood progenitor cells (PBPC) and leads to faster hematopoietic engraftment after autologous transplantation. STUDY DESIGN AND METHODS:A randomized, open-label, multicenter trial was car...

journal_title：Transfusion

authors： André M,Baudoux E,Bron D,Canon JL,D'Hondt V,Fassotte MF,D'Hondt L,Fillet G,Humblet Y,Jerusalem G,Vermeulen P,Symann M,Beguin Y

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Trypanosoma cruzi, the protozoan cause of Chagas disease, causes life-long infection and is easily transmitted by blood transfusion. Our goals were to determine the prevalence of Chagas disease among donors in five Mexican blood banks, to look for evidence of transmission of T. cruzi by transfusion, and to e...

journal_title：Transfusion

authors： Kirchhoff LV,Paredes P,Lomelí-Guerrero A,Paredes-Espinoza M,Ron-Guerrero CS,Delgado-Mejía M,Peña-Muñoz JG

更新日期：2006-02-01 00:00:00

abstract：:Acquired thrombotic thrombocytopenic purpura (TTP) is a disease characterized by microangiopathic hemolytic anemia and thrombocytopenia, in addition to variable fever and neurologic and renal dysfunction, without an underlying cause. Recent advances in elucidating the pathophysiology of acquired TTP have led to new te...

journal_title：Transfusion

authors： Raval JS,Mazepa MA,Brecher ME,Park YA

更新日期：2014-10-01 00:00:00