Determination of thromboelastographic responsiveness in stored single-donor platelet concentrates.

abstract：BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

journal_title：Transfusion

authors： Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Drug-induced immune pancytopenia is considered an uncommon disorder. CASE REPORT:A 76-year-old woman with metastatic gastric adenocarcinoma received 15 cycles of FOLFOX-6 (oxaliplatin/folinic acid/fluorouracil) with a complete response. Upon disease progression, she was restarted on FOLFOX; during the seven...

journal_title：Transfusion

authors： Fontão-Wendel R,Hoff PM,Lazar A,Freitas D,Novis Y,Patah P,Tsujita M,Balthazar A,Pierroti M,Wendel S

更新日期：2010-07-01 00:00:00

abstract：:Kell blood-group-active protein has been isolated by labeling red cell surface proteins with 125I, sensitizing intact cells with anti-K1, anti-K2, anti-K7, or anti-K22, solubilizing the cell membranes, isolating immune complexes, and separating their components by sodium dodecyl sulfate polyacrylamide gel electrophore...

journal_title：Transfusion

authors： Redman CM,Marsh WL,Mueller KA,Avellino GP,Johnson CL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Despite the clinical significance of red blood cell (RBC) alloantibodies, there are currently no laboratory tests available to predict which patients may be at risk of antibody formation after transfusion exposure. Given their phagocytic and inflammatory functions, we hypothesized that differences in circula...

journal_title：Transfusion

authors： Balbuena-Merle R,Curtis SA,Devine L,Gibb DR,Karafin MS,Luckey CJ,Tormey CA,Siddon AJ,Roberts JD,Hendrickson JE

更新日期：2019-10-01 00:00:00

abstract：:Retrospective studies suggest that the transfusion of older, stored red blood cells (RBCs) may be associated with increases in mortality, serious infections, multiorgan failure, thrombosis, and hospital length of stay. Our research is based on the overarching hypothesis that the adverse effects associated with transfu...

journal_title：Transfusion

authors： Hod EA,Spitalnik SL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Recently, long-standing elevations of soluble growth factors released from platelets (PLTs) after contact with artificial surfaces during dialysis were described. They could be jointly responsible for the high frequency of death from cardiovascular diseases in dialysis patients. There are no comparable data ...

journal_title：Transfusion

authors： Zimmermann R,Loew D,Weisbach V,Strasser E,Ringwald J,Zingsem J,Eckstein R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The clinical significance of alloimmunization to RBC antigens in sickle cell patients was analyzed by a retrospective review of the records of pediatric and adult sickle cell patients who received transfusions and who were followed over a 10-year period. STUDY DESIGN AND METHODS:Charts of pediatric and adul...

journal_title：Transfusion

authors： Aygun B,Padmanabhan S,Paley C,Chandrasekaran V

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Posttransfusion graft-versus-host disease (PT-GVHD) is underdiagnosed and underreported. Risk factors predisposing to PT-GVHD in newborn recipients, the clinical manifestations of the disease in newborns, and its mechanism are not well characterized. STUDY DESIGN AND METHODS:A literature review identified 2...

journal_title：Transfusion

authors： Ohto H,Anderson KC

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Plasma thawed and stored at 1 to 6° C for up to 5 days (thawed plasma [TP]) provides rapid availability in emergencies and reduces plasma waste, but it carries risks of coagulation factor loss or activation, bacterial outgrowth, and viral contamination. We characterized changes in amotosalen/ultraviolet A (U...

journal_title：Transfusion

authors： Erickson A,Waldhaus K,David T,Huang N,Rico S,Corash L,Mufti N,Benjamin RJ

更新日期：2017-04-01 00:00:00

abstract：:Our computer system currently stores donor blood types for seven years and checks typing of all repeat donors against these files. In a recent three-month period (42,500 units), five discrepancies were found--two representing current error. Retrospective analysis of 18 errors made over the last three years showed that...

journal_title：Transfusion

authors： Grindon AJ,Liles BA

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Beriplex P/N/Kcentra/Coaplex/Confidex is a four-factor human prothrombin complex concentrate (PCC). Here, we describe the pathogen safety profile and biochemical characteristics of an improved manufacturing process that further enhances the virus safety of Beriplex P/N. STUDY DESIGN AND METHODS:Samples of p...

journal_title：Transfusion

authors： Nowak T,Popp B,Gröner A,Schäfer W,Kalina U,Enssle K,Roth NJ

更新日期：2017-05-01 00:00:00

abstract：:Alanine aminotransferase (ALT) phenotype and serum activities were determined in 200 random volunteer blood donors. Serum enzyme activities were not significantly affected by the ALT phenotype (p greater than 0.1). Studies on 500 random volunteer blood donors showed significant differences in serum ALT levels between ...

journal_title：Transfusion

authors： Savage B,Sayers MH,Giblett ER

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) is a source of hematopoietic stem cells for transplantation, offering an alternative for patients unable to find a matched adult donor. UCB is also a versatile source of hematopoietic stem and progenitor cells (hCD34 + HSPCs) for research into hematologic diseases, in vitro expansi...

journal_title：Transfusion

authors： Mata MF,Hernandez D,Rologi E,Grandolfo D,Hassan E,Hua P,Kallmeier R,Hirani S,Heuts F,Tittrea V,Choo Y,Baradez MO,Watt SM,Tarunina M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versus-host disease (TA-GVHD) involves patient exposure to donor platelets (PLTs) and T lymphocytes, respectively, which are removed during blood component leukodepletion (LD). STUDY DESIGN AND METHODS:Reports of PTP and TA-G...

journal_title：Transfusion

authors： Williamson LM,Stainsby D,Jones H,Love E,Chapman CE,Navarrete C,Lucas G,Beatty C,Casbard A,Cohen H

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Blood bank inventories must balance adequate supply with minimal outdate rates. The day-to-day practice of ordering red blood cell (RBC) inventory usually involves manually comparing current inventory levels with predetermined thresholds calculated from historical usage and ordering the difference. To date, ...

journal_title：Transfusion

authors： Quinn J,Campbell C,Gomez A,Kumar-Misir A,Watson S,Liwski D,Covello T,Tennankore KK,Chisholm N,Sadek I,Cheng C

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Interventions intended to motivate donors to return can be costly and time consuming. The current study examined the effect of a Web-based automated interview, informed by motivational interviewing and self-determination theory, on donor intention, motivation, and behavior in a sample of highly experienced d...

journal_title：Transfusion

authors： Livitz IE,France CR,France JL,Fox KR,Ankawi B,Slepian PM,Kessler DA,Rebosa M,Shaz BH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Throughout history, blood has been embedded with powerful and paradoxical connotations. In the last decades, a more rational conception based on scientific knowledge has emerged, portraying blood as a "disenchanted" and utilitarian object, hence more apt for donation between strangers. This study aims to exa...

journal_title：Transfusion

authors： Charbonneau J,Tran NY

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Future supply with allogeneic blood transfusions faces several crucial challenges that warrant thorough (re-)evaluation of existing alternatives. Meta-analyses have indicated a significant potential for autologous blood conservation (ABC) measures to reduce the need for allogeneic blood transfusions. The qua...

journal_title：Transfusion

authors： Singbartl G,Held AL,Singbartl K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Etoricoxib is a selective inhibitor of cyclooxygenase 2 used mainly to treat osteoarticular pain. Here, we report the case of a patient who developed acute kidney failure and immune hemolytic anemia after the use of etoricoxib. STUDY DESIGN AND METHODS:An 83-year-old female patient developed immune hemolyti...

journal_title：Transfusion

authors： Burgos Pratx L,Santoro D,Coca Mogro B,Valiente VL,Camino P,Scordo W,Salamone H

更新日期：2019-05-01 00:00:00

abstract：:Current criteria for a reactive (positive) interpretation on hepatitis C virus (HCV) recombinant immunoblot assay (RIBA) require > or = 1+ reactivity to at least two of the four HCV antigens present in the assay. Given that 5-1-1 is a subcomponent of c100-3, there is concern that donor samples reacting only with these...

journal_title：Transfusion

authors： Busch MP,Tobler L,Quan S,Wilber JC,Johnson P,Polito A,Steane E,Zola A,Bahl C,Nelles M

更新日期：1993-01-01 00:00:00

abstract：:We report here the results of our evaluation of two procedures to eliminate viruses in factor VIII and factor IX coagulation factor concentrates. Both procedures were equally effective in the in vitro destruction of marker viruses. However, in a controlled infectivity test in chimpanzees, treatment at 60 degrees C for...

journal_title：Transfusion

authors： Heldebrant CM,Gomperts ED,Kasper CK,McDougal JS,Friedman AE,Hwang DS,Muchmore E,Jordan S,Miller R,Sergis-Davenport E

更新日期：1985-11-01 00:00:00

abstract：:An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was dest...

journal_title：Transfusion

authors： Issitt PD,Valinsky JE,Marsh WL,DiNapoli J,Gutgsell NS

更新日期：1990-03-01 00:00:00

abstract：:Fatal postoperative erythroderma (POE) developed in a 52-year-old woman with gallstones who underwent elective cholecystectomy. During surgery, she was transfused with 3 units of unirradiated packed red cells stored in the liquid state for at least 4 days after collection. The POE is believed to have been the result o...

journal_title：Transfusion

authors： Otsuka S,Kunieda K,Hirose M,Takeuchi H,Mizutani Y,Nagaya M,Sato G,Kasuya S,Matsutomo K,Noma A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Brucellosis is a severe zoonotic disease that is increasingly prevalent in north China. A study evaluating Brucella infection in blood donors was conducted at Kashi central blood station, Xinjiang, China. STUDY DESIGN AND METHODS:Four serologic and two molecular methods of detection of Brucella infection we...

journal_title：Transfusion

authors： Wang W,Liao Q,Wu X,Hou S,Wang Y,Wu J,Shen C,Chen S,Allain JP,Li C

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Blood transfusion has been cited as one of the five most overutilized therapeutic procedures in the United States. We assessed the impact of clinical decision support at computerized physician order entry and education on red blood cell (RBC) transfusions and clinical patient outcomes at our institution. ST...

journal_title：Transfusion

authors： Goodnough LT,Maggio P,Hadhazy E,Shieh L,Hernandez-Boussard T,Khari P,Shah N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:In cases of warm autoimmune hemolytic anemia (WAIHA), crossmatch incompatible RBCs are most often used for transfusion. The determination of the in vivo survival of transfused and autologous RBCs in WAIHA is helpful in the assessment of the efficacy of transfusion and other therapeutic interventions. CASE R...

journal_title：Transfusion

authors： Zeiler T,Müller JT,Hasse C,Kullmer J,Kretschmer V

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:In 1996, the Danish National Board of Health recommended hepatitis C virus (HCV) lookback to identify recipients of blood components from donors found to be positive since the implementation of anti-HCV screening in 1991. STUDY DESIGN AND METHODS:The aim was to accumulate results of the lookback at a nation...

journal_title：Transfusion

authors： Christensen PB,Groenbaek K,Krarup HB

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Hypericin is a potent virucidal agent with activity against a broad range of enveloped viruses and retroviruses. The effective virucidal activity emanates from a combination of photodynamic and lipophilic properties. Hypericin binds cell membranes (and, by inference, virus membranes) and crosslinks virus cap...

journal_title：Transfusion

authors： Lavie G,Mazur Y,Lavie D,Prince AM,Pascual D,Liebes L,Levin B,Meruelo D

更新日期：1995-05-01 00:00:00