In vivo red cell destruction by anti-Lu6.

abstract：BACKGROUND:The 1000 Genomes Project provides a database of genomic variants from whole genome sequencing of 2504 individuals across five continental superpopulations. This database can enrich our background knowledge of worldwide blood group variant geographic distribution and identify novel variants of potential clini...

journal_title：Transfusion

authors： Montemayor-Garcia C,Karagianni P,Stiles DA,Reese EM,Smellie DA,Loy DA,Levy KY,Nwokocha M,Bueno MU,Miller JL,Klein HG

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:A size-exclusion filter (Viresolve 180, Millipore Corp.) was tested for its ability to remove transmissible spongiform encephalopathies prion protein from an immune globulin preparation during ultrafiltration. STUDY DESIGN AND METHODS:Hamster-adapted 263K scrapie brain homogenate (SBH) was spiked into Rh0(D...

journal_title：Transfusion

authors： Van Holten RW,Autenrieth S,Boose JA,Hsieh WT,Dolan S

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Because the frequency of umbilical cord blood (UCB) stem cell transplantation has increased, the quality of UCB available in banks is an important part of the success of UCB stem cell transplants. STUDY DESIGN AND METHODS:A quality assurance monitoring system was used to evaluate 268 UCB units provided to u...

journal_title：Transfusion

authors： McCullough J,McKenna D,Kadidlo D,Schierman T,Wagner J

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Prosthetic hip-associated cobalt toxicity (PHACT) is an uncommon, but potentially devastating, complication for patients with metal-on-metal hip implants (MoMs). Clinical management of PHACT is poorly defined, with primary intervention being MoM explant followed by chelation therapy. Therapeutic plasma excha...

journal_title：Transfusion

authors： Grant ML,Karp JK,Palladino M,Le N,Hall N,Herman JH

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Idarucizumab (IDA) is approved for emergency reversal of dabigatran; prothrombin complex concentrates (PCCs) are recommended in the absence of specific antidote. The combined effects of IDA and PCC in trauma-related bleeding are unknown. The efficacy and safety of combined IDA + PCC were assessed in a lethal...

journal_title：Transfusion

authors： Honickel M,Braunschweig T,Rossaint R,Schöchl H,Grottke O

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS:In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and ...

journal_title：Transfusion

authors： Reiher VSA,Hönger G,Infanti L,Passweg JR,Hösli I,Frey BM,Gassner C,Meyer S,Buser AS,Holbro A,Schaub S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:When bacteria are found, after a platelet transfusion, in the recipient's blood as well as in the platelet concentrate (PC), a causal relationship is normally suspected, with the PC as the causative agent. The other alternative, that the patient has bacteremia and contaminated the PC, is less well documented...

journal_title：Transfusion

authors： Engstrand M,Engstrand L,Högman CF,Hambraeus A,Branth S

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) storage at 0 to 4 degrees C suppresses bacterial multiplication, but induces clusters of glycoprotein (GP) Ibalpha that trigger their phagocytosis by macrophages and reduce their survival after transfusion. A method was sought that detects cold-induced changes in GPIbalpha involved in phagocyt...

journal_title：Transfusion

authors： Badlou BA,Spierenburg G,Ulrichts H,Deckmyn H,Smid WM,Akkerman JW

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Phthalocyanines are useful sensitizers for photodynamic sterilization of red cell concentrates. Various lipid-enveloped viruses can be inactivated with only limited red cell damage. Because white cells are involved in the immunomodulatory effects of blood transfusions, the study of the effect of photodynamic...

journal_title：Transfusion

authors： Moor AC,van der Veen A,Dubbelman TM,VanSteveninck J,Brand A

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

journal_title：Transfusion

authors： Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Allogeneic transfusion can result in alloimmunization, leading to platelet (PLT) refractoriness and rejection of solid organ transplants. Previously we demonstrated that pathogen reduction using UV light and riboflavin (UV + R) eliminates the immunogenicity of white blood cells (WBCs) in vitro, blocks alloim...

journal_title：Transfusion

authors： Muench MO,Heitman JW,Inglis H,Fomin ME,Marschner S,Goodrich RP,Norris PJ,Jackman RP

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Whole blood donors may experience post-donation symptoms such as fatigue, dizziness, or headache after blood donation, which could influence donor retention. We aimed to examine post-donation symptoms during 1 week after whole blood donation, investigate donor characteristics associated with symptoms, and ev...

journal_title：Transfusion

authors： Sweegers MG,Twisk JWR,Quee FA,Ferguson E,van den Hurk K

更新日期：2021-01-23 00:00:00

abstract：:Lyophilized factor VIII concentrates, because of their convenience, are the most commonly used products for providing antihemophilic factor to patients with hemophilia A. Heightened concerns about associated complications indicate that cryoprecipitate usage will increase in the immediate future. We present a protocol ...

journal_title：Transfusion

authors： Menitove JE,Spero JA,Richards WA,Lewis JH,Montgomery RR,Gill JC,Hasiba U,Wheeler DV,Sherwin JA,Russell-Vaskov S,Marlar RA,Maxwell NG,Aster RH

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Human natural killer (NK) cells are thought to play a role in antiviral response and tumor immune surveillance. The molecular mechanisms of down regulation of NK-cell activity observed after red blood cell (RBC) transfusion is still undefined. STUDY DESIGN AND METHODS:Both effects of blood transfusion (ex v...

journal_title：Transfusion

authors： Ghio M,Contini P,Negrini S,Mazzei C,Zocchi MR,Poggi A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:National guidance recommends planning for future blood shortages, but few studies have evaluated how reduced demand could be achieved acutely. STUDY DESIGN AND METHODS:A trained observer collected data concerning red blood cell (RBC) transfusion events outside the operating theater during 68 hours of blood ...

journal_title：Transfusion

authors： Joseph BG,Hendry C,Walsh TS

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS:Double-dose PLTs (n = 15) were generated using a commercially available aphere...

journal_title：Transfusion

authors： Picker SM,Tauszig ME,Gathof BS

更新日期：2012-03-01 00:00:00

abstract：:The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

journal_title：Transfusion

authors： Rock G,Tocchi M,Ganz PR,Tackaberry ES

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig)G replacement with intravenous or subcutaneous immunoglobulins is a lifelong substitutive therapy in patients with primary antibody deficiencies (PADs). Hemolysis after immunoglobulin therapy was described in patients receiving high immunoglobulin dosages. The issue of hemolysis after immu...

journal_title：Transfusion

authors： Quinti I,Pulvirenti F,Milito C,Granata G,Giovannetti G,La Marra F,Pesce AM,Farrugia A,Coluzzi S,Girelli G

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV-1 to -4), mosquito-borne flaviviruses with increasing incidence, and expanding global distributions. Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV. METHO...

journal_title：Transfusion

authors： Linnen JM,Vinelli E,Sabino EC,Tobler LH,Hyland C,Lee TH,Kolk DP,Broulik AS,Collins CS,Lanciotti RS,Busch MP

更新日期：2008-07-01 00:00:00

abstract：:ADAMTS13 is an enzyme that acts by cleaving prothrombotic von Willebrand factor (VWF) multimers from the vasculature in a highly regulated manner. In pathologic states such as thrombotic thrombocytopenic purpura (TTP) and other thrombotic microangiopathies (TMAs), VWF can bind to the endothelium and form large multime...

journal_title：Transfusion

authors： Plautz WE,Raval JS,Dyer MR,Rollins-Raval MA,Zuckerbraun BS,Neal MD

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The Q fever outbreaks in the Netherlands in 2007 to 2009 initiated discussion on the necessity of measures to prevent transmission through blood products. Risk assessments help transfusion regulators decide when and where measures are required. This study assesses the transfusion transmission (TT) risk of Q ...

journal_title：Transfusion

authors： Oei W,Kretzschmar ME,Zaaijer HL,Coutinho R,van der Poel CL,Janssen MP

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Washing of red blood cell concentrates (RCCs) is required for potassium-sensitive transfusion recipients, including neonates in need of large-volume transfusions. When open, nonsterile washing systems are used, postwash outdate time is limited to 24 hours, often leading to problems providing the component to...

journal_title：Transfusion

authors： Hansen A,Yi QL,Acker JP

更新日期：2013-08-01 00:00:00

abstract：:With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

journal_title：Transfusion

authors： Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:A novel apheresis procedure for a blood separator (MCS+, Haemonetics) enables the collection of 2 WBC-reduced RBC units in a single donation by using one disposable set with one in-line WBC-reduction filter (RC2H, Pall Corp.). The objective of this study was to evaluate the filtration performance in connecti...

journal_title：Transfusion

authors： Bandarenko N,Rose M,Kowalsky RJ,Baston RK,Brecher ME,Elfath MD,Whitley P,Heminway M,Holme S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Treatment of hemophilia patients with recombinant factor VIII concentrates has not previously been associated with anaphylaxis. STUDY DESIGN AND METHODS:A 5-week-old boy with severe hemophilia A developed dyspnea, cyanosis, hypotension, and a diffuse urticarial rash following treatment with a recombinant fa...

journal_title：Transfusion

authors： Shopnick RI,Kazemi M,Brettler DB,Buckwalter C,Yang L,Bray G,Gomperts ED

更新日期：1996-04-01 00:00:00

abstract：:Fatal postoperative erythroderma (POE) developed in a 52-year-old woman with gallstones who underwent elective cholecystectomy. During surgery, she was transfused with 3 units of unirradiated packed red cells stored in the liquid state for at least 4 days after collection. The POE is believed to have been the result o...

journal_title：Transfusion

authors： Otsuka S,Kunieda K,Hirose M,Takeuchi H,Mizutani Y,Nagaya M,Sato G,Kasuya S,Matsutomo K,Noma A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...

journal_title：Transfusion

authors： Assal A,Barlet V,Deschaseaux M,Dupont I,Gallian P,Guitton C,Morel P,David B,De Micco P

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Donor stimulation with granulocyte-colony-stimulating factor (G-CSF) has increased the number of neutrophils (PMNs) that can be collected for granulocyte transfusion therapy. Clinical utility, however, has been limited by the inability to store functional PMNs ex vivo. This study was conducted to determine w...

journal_title：Transfusion

authors： Hubel K,Rodger E,Gaviria JM,Price TH,Dale DC,Liles WC

更新日期：2005-12-01 00:00:00