Abstract:
BACKGROUND:The Q fever outbreaks in the Netherlands in 2007 to 2009 initiated discussion on the necessity of measures to prevent transmission through blood products. Risk assessments help transfusion regulators decide when and where measures are required. This study assesses the transfusion transmission (TT) risk of Q fever using the European Up-Front Risk Assessment Tool (EUFRAT) model. STUDY DESIGN AND METHODS:We estimated the number of Q fever infections in recipients during the 2007 to 2009 outbreaks' peaks using selected notification data; estimates are calculated from the probability of a donor being infected. We compared this probability to the prevalence of infection estimated from an independent donation testing study and using the Biggerstaff model. We also quantified the risk reduction by implementing measures such as donation testing and donor deferral. RESULTS:At the peak of the 2007, 2008, and 2009 outbreaks, there were an estimated 0.21, 0.96, and 1.59 recipients infected with Q fever, respectively. Between June 1, 2009, and January 31, 2010, the probability of a donor being infected with Q fever in the high-incidence areas was estimated at 260 (95% confidence interval, 192-340) per 100,000 donors, consistent with results from the donation testing study. The EUFRAT estimates were also consistent with estimates from the Biggerstaff model. Scenario analyses showed that donation testing provided the largest risk reduction of various risk reduction strategies. CONCLUSION:The TT risk of Q fever during the 2007 to 2009 outbreaks was small, a result that is consistent with results of other studies. EUFRAT can be applied successfully to support decision making during outbreaks.
journal_name
Transfusionjournal_title
Transfusionauthors
Oei W,Kretzschmar ME,Zaaijer HL,Coutinho R,van der Poel CL,Janssen MPdoi
10.1111/trf.12539subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1705-11issue
7eissn
0041-1132issn
1537-2995journal_volume
54pub_type
杂志文章相关文献
TRANSFUSION文献大全abstract:BACKGROUND:Nonenveloped transfusion-transmissible viruses such as hepatitis A virus (HAV) and hepatitis E virus (HEV) are resistant to many of the common virus inactivation procedures for blood products. This study investigated the pathogen inactivation (PI) efficacy of the THERAFLEX UV-Platelets system against two non...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.14957
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.16112
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Preliminary evidence of cases of acute occult hepatitis B virus (HBV) infection (OBI) has been recently reported in the literature. Furthermore, OBI definition has been the object of an international consensus conference. STUDY DESIGN AND METHODS:A case of acute primary OBI was identified and followed up in...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2008.02041.x
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:When xenotropic murine leukemia virus-related virus (XMRV) was first reported in association with chronic fatigue syndrome, it was suggested that it might offer a risk to blood safety. Thus, the prevalence of the virus among blood donors and, if present, its transmissibility by transfusion need to be defined...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2011.03450.x
更新日期:2012-02-01 00:00:00
abstract::Since the first issue of TRANSFUSION in 1961, there has been a tremendous expansion in not only the number of blood group antigens identified but also in our knowledge of their biochemical basis, function, and more recently, associated DNA changes. As certain techniques became available, our ability to discover and el...
journal_title:Transfusion
pub_type: 历史文章,杂志文章
doi:10.1111/j.1537-2995.2009.02456.x
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:The clinical significance of alloimmunization to RBC antigens in sickle cell patients was analyzed by a retrospective review of the records of pediatric and adult sickle cell patients who received transfusions and who were followed over a 10-year period. STUDY DESIGN AND METHODS:Charts of pediatric and adul...
journal_title:Transfusion
pub_type: 杂志文章,多中心研究,评审
doi:10.1046/j.1537-2995.2002.00007.x
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:To improve productivity of automated platelet (PLT) collection, the industry has introduced new instruments or modifications to existing equipment. STUDY DESIGN AND METHODS:With the same 8 donors for double (DDC) and triple-dose PLT collection (TDC), the Baxter Amicus (AM), the Haemonetics MCS Plus (MCS+), ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2006.00928.x
更新日期:2006-09-01 00:00:00
abstract::Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1979.19279160288.x
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:The ABO blood group is a major determinant in living donor kidney transplantation since AB antigens are expressed on renal tissue. Little attention has been directed to the ABH-secretor status of the donor kidney. As renal tissue is capable of secreting soluble ABH antigens in secretors, we examined the infl...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13711
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Donor stimulation with granulocyte-colony-stimulating factor (G-CSF) has increased the number of neutrophils (PMNs) that can be collected for granulocyte transfusion therapy. Clinical utility, however, has been limited by the inability to store functional PMNs ex vivo. This study was conducted to determine w...
journal_title:Transfusion
pub_type: 临床试验,杂志文章
doi:10.1111/j.1537-2995.2005.00636.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2005.04387.x
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.15707
更新日期:2020-04-01 00:00:00
abstract::A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1987.27287150183.x
更新日期:1987-03-01 00:00:00
abstract::Cell pheresis was employed in the initial management of a pregnant patient with chronic myelocytic leukemia (CML). Reduction in circulating leukocyte and platelet counts was evident after two weeks of therapy. This technique is an effective mode of management of the pregnant patient with CML and may play an important ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1978.18178118555.x
更新日期:1978-01-01 00:00:00
abstract::The vasodilative effects associated with the use of sodium acetate have been reported in the literature. Preparations of plasma protein fraction (PPF) substantially free of this vasodilator were developed. This paper presents and discusses experimental work on the improved product. ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1981.21682085754.x
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:A previous study in our hospitals correlated suboptimal documentation and failure to justify transfusions. In light of implemented blood-conservation strategies, including patient blood management (PBM) and prospective audits (PAs), we performed a follow-up study. STUDY DESIGN AND METHODS:We reviewed prospe...
journal_title:Transfusion
pub_type: 杂志文章,多中心研究
doi:10.1111/trf.13917
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13296
更新日期:2015-12-01 00:00:00
abstract::We investigated the possibility that the functional impairment in neutrophil (PMN) chemotaxis which occurs during granulocyte concentrate storage might be due to autotoxicity from the release of neutrophil granule contents during storage. Preliminary experiments confirmed that the exposure of fresh PMNs to the intrace...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1985.25285169211.x
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:The need for blood products is constant and unremitting, yet only a small percentage of eligible individuals answer the appeal to donate. Further, most new donors never return to provide a repeat donation. The ongoing need to attract and retain new donors has led to the examination of psychosocial factors th...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2007.01236.x
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:The infusion of citrate during apheresis may affect the levels of ionized magnesium in the blood. Hypomagnesemia and concomitant hypocalcemia could influence the parathormone response and could be responsible for some of the symptoms observed during apheresis. STUDY DESIGN AND METHODS:The study reports meas...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1997.37497265343.x
更新日期:1997-04-01 00:00:00
abstract:INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.15652
更新日期:2020-06-01 00:00:00
abstract::The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and c...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1988.28588337343.x
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Cellular blood components are irradiated to prevent graft-versus-host disease in transfusion recipients at risk for this syndrome. Because gamma radiation can result in the production of reactive oxygen species, the role of reactive oxygen species was investigated in radiation-induced red cell damage. STUDY...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1997.37297203518.x
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:New alloantibody formation is unpredictable in patients who have been previously alloimmunized. Pretransfusion testing is designed to detect these antibodies while antibody identification (ABI) techniques are designed to identify the specificity of the antibody. Pretransfusion testing intervals are prescribe...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13380
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.15651
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Etoricoxib is a selective inhibitor of cyclooxygenase 2 used mainly to treat osteoarticular pain. Here, we report the case of a patient who developed acute kidney failure and immune hemolytic anemia after the use of etoricoxib. STUDY DESIGN AND METHODS:An 83-year-old female patient developed immune hemolyti...
journal_title:Transfusion
pub_type:
doi:10.1111/trf.15226
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The use of a platelet additive solution (PAS-II, Baxter) may have benefits over plasma for storage of platelets. It was the aim of this study to develop a method to produce WBC-reduced platelet concentrates (PCs) in PAS-II with >240 x 10(9) platelets and <1 x 10(6) WBCs per unit, which can be stored for 5 da...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2001.41070917.x
更新日期:2001-07-01 00:00:00
abstract::The quantity of anti-IgG bound at equilibrium to cell-bound anti-D failed to increase with enzymatic modification of intact red blood cells. This contrasts with results obtained by immunoelectronmicroscopy with unsealed red blood cell ghosts. Ghosts derived from enzyme-modified, anti-D-sensitized intact red blood cell...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1980.20480260268.x
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:All studied photosensitizers for virus inactivation impair RBCs. To reduce damage to the RBCs without affecting virucidal activity, selective protection of the RBCs is necessary. The ability of the band 3 ligand, dipyridamole, to react with singlet oxygen and to increase the selectivity of photosterilization...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2000.40111330.x
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Platelets (PLTs) are especially affected by the risk of bacterial contamination. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) is an accurate method for the routine identification of bacterial isolates in microbiology laboratories. We directly applied the MALDI-TOF method to bacteria...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.14430
更新日期:2018-03-01 00:00:00