Can the interval between antibody identifications be increased for alloimmunized patients?

abstract：BACKGROUND:Drug-induced immune pancytopenia is considered an uncommon disorder. CASE REPORT:A 76-year-old woman with metastatic gastric adenocarcinoma received 15 cycles of FOLFOX-6 (oxaliplatin/folinic acid/fluorouracil) with a complete response. Upon disease progression, she was restarted on FOLFOX; during the seven...

journal_title：Transfusion

authors： Fontão-Wendel R,Hoff PM,Lazar A,Freitas D,Novis Y,Patah P,Tsujita M,Balthazar A,Pierroti M,Wendel S

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) is a source of hematopoietic stem cells for transplantation, offering an alternative for patients unable to find a matched adult donor. UCB is also a versatile source of hematopoietic stem and progenitor cells (hCD34 + HSPCs) for research into hematologic diseases, in vitro expansi...

journal_title：Transfusion

authors： Mata MF,Hernandez D,Rologi E,Grandolfo D,Hassan E,Hua P,Kallmeier R,Hirani S,Heuts F,Tittrea V,Choo Y,Baradez MO,Watt SM,Tarunina M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The Joint Commission on the Accreditation of Healthcare Organizations requires that hospitals have a planned approach to systematically collect data on processes related to the use, ordering, and administering of blood components. This study describes how a comprehensive blood-administering assessment progra...

journal_title：Transfusion

authors： Saxena S,Ramer L,Shulman IA

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:A quality monitoring program (QMP) for platelet concentrates (PCs) was implemented at Canadian Blood Services (CBS) to improve standards and to better understand platelet (PLT) products by supplementing routine quality control (QC). STUDY DESIGN AND METHODS:Annual surveys of PCs from CBS production sites we...

journal_title：Transfusion

authors： Levin E,Jenkins C,Culibrk B,Gyöngyössy-Issa MI,Serrano K,Devine DV

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Cryopreserved umbilical cord blood (CB) is increasingly used as a cell source to reconstitute marrow in hematopoietic stem cell transplant patients. Delays in cryopreservation may adversely affect cell viability, thereby reducing their potential for engraftment after transplantation. STUDY DESIGN AND METHOD...

journal_title：Transfusion

authors： Guttridge MG,Soh TG,Belfield H,Sidders C,Watt SM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:In spite of interventions, approximately 1000 per 1,000,000 platelet (PLT) collections are contaminated with bacteria at collection. The current prestorage culture procedure at some blood centers is to inoculate a fixed volume from the collection bag (4-8 mL) regardless of collection volume. The sensitivity ...

journal_title：Transfusion

authors： Tomasulo PA,Wagner SJ

更新日期：2013-04-01 00:00:00

abstract：:A procedure is described for the large-scale production of pure suspensions of human lymphocytes and granulocytes. Platelet-poor buffy-coats, obtained by centrifugation of six units of ABO-compatible ACD blood, were pooled and centrifuged again, resulting in a crude leukocyte concentrate containing approximately 60 pe...

journal_title：Transfusion

authors： de la Rivière AB,Verhoef-Karssen PR,de Wit JJ,Loos JA,Prins HK

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Although the risk of transmitting infectious agents by blood transfusion is dramatically reduced after donor selection, leukoreduction, and laboratory testing, some could still be present in donor's blood. A description of metagenomes in blood products eligible for transfusion represents relevant information...

journal_title：Transfusion

authors： Lau P,Cordey S,Brito F,Tirefort D,Petty TJ,Turin L,Guichebaron A,Docquier M,Zdobnov EM,Waldvogel-Abramowski S,Lecompte T,Kaiser L,Preynat-Seauve O

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:A new citrate-acetate-NaCl platelet additive solution, identified as PAS 2, was developed to prepare platelet concentrates (PCs) from pooled 0.5 CPD buffy coats (BCs). STUDY DESIGN AND METHODS:A study was undertaken to evaluate PAS 2 in vitro (n = 8) and in vivo (n = 9) against a commercially available solu...

journal_title：Transfusion

authors： van Rhenen DJ,Vermeij H,Kappers-Klunne M,Payrat JM

更新日期：1995-01-01 00:00:00

abstract：:Adenine is an approved additive to citrate-phosphate-dextrose anticoagulant for whole blood collection and extends the storage life of red blood cells. We used in vitro methods to investigate the effects of adenine on platelet function and viability during 72 hours of storage at 22 degrees C. Although the hypotonic sh...

journal_title：Transfusion

authors： Wong SC,Rock G

更新日期：1982-07-01 00:00:00

abstract：:Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

journal_title：Transfusion

authors： Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Hemolytic transfusion reactions are a rare, yet serious complication of red blood cell (RBC) transfusion. Patients with sickle cell disease (SCD) are at an increased risk for such reactions, because they are prone to make alloantibodies against transfused RBCs, complicating this integral part of their diseas...

journal_title：Transfusion

authors： Dean CL,Maier CL,Roback JD,Stowell SR

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：:Prior studies have suggested that a high percentage of blood transfusions to hospital patients are unnecessary. If such transfusions can be reduced, more blood would be made available for those patients with legitimate blood requirements. In this study, blood transfusion of 401 nonoperated hospital patients with anemi...

journal_title：Transfusion

authors： Friedman BA

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Our study characterizes blood use in the ambulatory setting by US elderly Medicare beneficiaries during 2001. As the US population ages and delivery of health care in outpatient settings is on the rise, ambulatory blood utilization is expected to increase. There is currently a lack of broad population-based ...

journal_title：Transfusion

authors： Menis M,Burwen DR,Holness L,Anderson SA

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

journal_title：Transfusion

authors： Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

更新日期：2006-12-01 00:00:00

abstract：:The purpose of this study was to ascertain the cause for seasonal variations of donor deferral. Deferred donors and monthly temperatures from 1981 to 1984 were tallied and analyzed. Temperatures were categorized at 10-degree intervals from 15 degrees F to 75 degrees F. Donors failing the hemoglobin screening then unde...

journal_title：Transfusion

authors： Lau P,Hansen M,Sererat M

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize the fibrin clot. A bovine protein, this substance has an allergenic potency. CASE REPORT:This case report present...

journal_title：Transfusion

authors： Beierlein W,Scheule AM,Antoniadis G,Braun C,Schosser R

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

journal_title：Transfusion

authors： Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV-1 to -4), mosquito-borne flaviviruses with increasing incidence, and expanding global distributions. Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV. METHO...

journal_title：Transfusion

authors： Linnen JM,Vinelli E,Sabino EC,Tobler LH,Hyland C,Lee TH,Kolk DP,Broulik AS,Collins CS,Lanciotti RS,Busch MP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick r...

journal_title：Transfusion

authors： Clavier B,Pouget T,Sailliol A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Monitoring of patients' vital sign values (VSVs) during hemotherapy may have an important role in the recognition and mitigation of transfusion-associated circulatory overload (TACO). Knowledge regarding VSVs and other patient characteristics in bedside-reported TACO or fluid challenge-suspected transfusion ...

journal_title：Transfusion

authors： Andrzejewski C Jr,Popovsky MA,Stec TC,Provencher J,O'Hearn L,Visintainer P,Steingrub J

更新日期：2012-11-01 00:00:00

abstract：:Interest has been renewed in CPD-adenine as a long-term liquid blood preservative. The question of whether the metabolic product of adenine, 2,8-dioxyadenine was toxic to humans has apparently been resolved by extensive animal and human studies in favor of there being no potential toxicity in the amounts used in blood...

journal_title：Transfusion

authors： Dawson RB,Ellis TJ,Hershey RT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The Joint Commission has highlighted the importance of having appropriate and complete pretransfusion testing before surgery begins. The maximum surgical blood ordering schedule (MSBOS) indicates which patients require preoperative transfusion testing. We determined the number of times surgical delays were c...

journal_title：Transfusion

authors： McWilliams B,Yazer MH,Cramer J,Triulzi DJ,Waters JH

更新日期：2012-10-01 00:00:00

abstract：:Cell pheresis was employed in the initial management of a pregnant patient with chronic myelocytic leukemia (CML). Reduction in circulating leukocyte and platelet counts was evident after two weeks of therapy. This technique is an effective mode of management of the pregnant patient with CML and may play an important ...

journal_title：Transfusion

authors： Caplan SN,Coco FV,Berkman EM

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:The Japanese Red Cross (JRC) implemented a fully automated pooling and nucleic acid amplification test (NAT) system for testing seronegative donations. The JRC sample repository and repeat blood donations allowed for lookback and follow-up studies of hepatitis B virus (HBV) DNA-positive donors, who tested ne...

journal_title：Transfusion

authors： Yoshikawa A,Gotanda Y,Minegishi K,Taira R,Hino S,Tadokoro K,Ohnuma H,Miyakawa K,Tachibana K,Mizoguchi H,Japanese Red Cross NAT Screening Research Group.

更新日期：2007-07-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:A highly sensitive dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA) and flow cytometry techniques have previously been developed and employed to characterize soluble cellular prion protein (PrP(c)) expression in whole blood and separated components from healthy adult blood donors. No previous stud...

journal_title：Transfusion

authors： Fagge T,Barclay GR,Macgregor I,Head M,Ironside J,Turner M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Fc gamma RIIIb deficiency is a rare defect in which neutrophils do not express Fc gamma RIIIb and therefore the individuals with this defect have an NA null phenotype. Soluble Fc gamma RIII in plasma is severely decreased and almost undetectable. During pregnancy, Fc gamma RIIIb deficiency may cause the form...

journal_title：Transfusion

authors： Puig N,de Haas M,Kleijer M,Montoro JA,Pérez A,Villalba JV,Gomez I,von dem Borne AE

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Early identification of acute traumatic coagulopathy is a key challenge during initial management to determine whether to initiate early hemostatic support. We assessed the performance of prothrombin time (PT) at point-of-care in trauma patients to detect moderate and severe coagulopathy on admission. STUDY...

journal_title：Transfusion

authors： Deras P,Nouri J,Martinez O,Aubry E,Capdevila X,Charbit J

更新日期：2018-07-01 00:00:00