Abstract:
:Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line after the first collection of leukocytes and platelets, but before it was returned to the donor. Although the citrate anticoagulant was returned to the donor and there were some decreases in the concentrations of fibrinogen, platelets, and factors V and VIII, there were no changes of sufficient degree to suggest that development of a potential bleeding disorder. In addition there was no evidence to suggest that any activation of blood coagulation occurred during the pheresis or that thrombogenic substances were returned to the donors. Combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor, therefore, do not appear to subject the donor to risks for either bleeding or thrombotic complications.
journal_name
Transfusionjournal_title
Transfusionauthors
Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JSdoi
10.1046/j.1537-2995.1979.19279160288.xsubject
Has Abstractpub_date
1979-03-01 00:00:00pages
173-7issue
2eissn
0041-1132issn
1537-2995journal_volume
19pub_type
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