Abstract:
:Previous studies have shown that some examples of anti-M and anti-N fail to agglutinate neuraminidase-treated (NeuNAc-depleted) red cells. This investigation extends those observations and shows that the antibodies fail to bind to such treated red cells. These observations may mean that NeuNAc residues act to orient the protein portion of the MN sialoglycoprotein so that it is recognized by the antibodies. Alternatively, it is possible that NeuNAc residues are an integral part of the antigen defined.
journal_name
Transfusionjournal_title
Transfusionauthors
Issitt PD,Wilkinson SLdoi
10.1046/j.1537-2995.1983.23283172846.xsubject
Has Abstractpub_date
1983-03-01 00:00:00pages
117-9issue
2eissn
0041-1132issn
1537-2995journal_volume
23pub_type
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