Four-year survival of transfusion recipients identified by hepatitis C lookback.

Abstract:

BACKGROUND:Information on the probability of survival of transfused patients is needed for policy making, but there is a paucity of empirical research into this question. A Swedish population-based study reported that the 40-month posttransfusion probability of survival was 51 percent in all patients and 41 percent in recipients of more than 10 units of blood and blood components. These figures were 20 percent lower than the figures reported previously from Olmsted County, Minnesota. STUDY DESIGN AND METHODS:Information was collected on the 4-year survival of 695 patients transfused at the New York University Medical Center between 1988 and 1996. These patients had been identified previously by hepatitis C lookback. RESULTS:Seventy-five percent of patients survived at 1 month after transfusion, 66 percent at 3 months, 60 percent at 6 months, 54 percent at 1 year, 50 percent at 2 years, 45 percent at 3 years, and 41 percent at 4 years. Seventy-eight percent of patients included in the study had received more than 10 units of blood and blood components. The 4-year survival of patients receiving 1 to 3, 4 to 10, or more than 10 units was 62 percent, 48 percent, and 38 percent, respectively (p < 0.0001). CONCLUSIONS:When transfusion dose is taken into account, the probability of survival of patients transfused at the New York University Medical Center in 1988 to 1996 and identified by lookback is similar to that reported for Swedish county residents transfused in 1993. Based on both the Swedish data and the information presented here and in the absence of any recent results from population-based studies, the survival of U.S. patients transfused in the 1990s appears to be 20 percent lower than that of Olmsted County residents transfused in 1981.

journal_name

Transfusion

journal_title

Transfusion

authors

Vamvakas EC,Goldstein R

doi

10.1046/j.1537-2995.2002.00109.x

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

691-7

issue

6

eissn

0041-1132

issn

1537-2995

pii

trf109

journal_volume

42

pub_type

杂志文章
  • Studies on the blood of a Co (a-b-) proposita and her family.

    abstract::The serum of a pregnant woman whose red cells typed as Co(a-b-) contained an alloantibody that, at the time of the infants delivery, was hemolytic in vitro and had a titer of 32,000 by the antiglobulin test. This antibody, which reacted with cells of all Colton-phenotypes except the proposita's own cells, showed very ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27387235637.x

    authors: Lacey PA,Robinson J,Collins ML,Bailey DG,Evans CC,Moulds JJ,Daniels GL

    更新日期:1987-05-01 00:00:00

  • Meropenem-induced immune thrombocytopenia and the diagnostic process of laboratory testing.

    abstract:BACKGROUND:Drug-induced immune thrombocytopenia (DITP) is a serious, life-threatening clinical syndrome, the diagnosis of which is consistently difficult. In this report, we present a case of DITP caused by meropenem that was confirmed by laboratory tests. CASE REPORT:A 59-year-old male patient developed severe thromb...

    journal_title:Transfusion

    pub_type:

    doi:10.1111/trf.14267

    authors: Huang R,Cai GQ,Zhang JH,Liu FX,Ma JQ,Liu H,Nie XM,Gui R

    更新日期:2017-11-01 00:00:00

  • Incest diagnosis by comparison of alleles of mother and offspring at highly heterozygous loci.

    abstract:BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1994.34294143949.x

    authors: Wenk RE,Chiafari FA,Houtz T

    更新日期:1994-02-01 00:00:00

  • An analysis on the fate of a selection of blood products derived from cytomegalovirus-seronegative donors at three tertiary referral hospitals in Australia.

    abstract:BACKGROUND:Supply of cytomegalovirus (CMV)-seronegative blood products in Australia is an ongoing challenge. Requests for CMV-negative products are increasing with prediction that the demand will exceed supply by 2019. Clinical information evaluating how these products are being utilized by health providers within Aust...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.14459

    authors: Hirani R,Tohidi-Esfahani I,Mondy P,Irving DO

    更新日期:2018-03-01 00:00:00

  • Whole-blood leuko-depletion filters as a source of CD 34+ progenitors potentially usable in cell therapy.

    abstract:BACKGROUND:Used leuko-depletion filters (LDFs), containing billions of white blood cells (WBCs), are discarded. Because the steady-state blood contains low quantities of stem and progenitor cells that are retained in LDFs, the viability and the functional properties of mononuclear cells (MNCs) and CD 34+ cells recovere...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00677.x

    authors: Ivanovic Z,Duchez P,Morgan DA,Hermitte F,Lafarge X,Chevaleyre J,Praloran V,Dazey B,Vezon G,Boiron JM

    更新日期:2006-01-01 00:00:00

  • Recipient inflammation affects the frequency and magnitude of immunization to transfused red blood cells.

    abstract:BACKGROUND:Most alloantigens on transfused red blood cells (RBCs) are weakly immunogenic, with only a 2 to 6 percent overall immunization rate even in patients receiving multiple transfusions. Although recipient genetics may contribute to responder and/or nonresponder status, in most cases HLA type does not predict hum...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.00946.x

    authors: Hendrickson JE,Desmarets M,Deshpande SS,Chadwick TE,Hillyer CD,Roback JD,Zimring JC

    更新日期:2006-09-01 00:00:00

  • Preparation of commercial quantities of a hyperimmune human intravenous immunoglobulin preparation against an emerging infectious disease: the example of pandemic H1N1 influenza.

    abstract:BACKGROUND:The recent H1N1 pandemic provided an opportunity to conceptually assess the possibility of rapidly providing a "hyperimmune" human immunoglobulin (H-IVIG) to an emerging infectious disease, in useful quantities with respect to public health. Commercial-scale H-IVIG production from plasma collected from donor...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03347.x

    authors: Kreil TR,Mc Vey JK,Lei LS,Camacho L,Wodal W,Kerschbaum A,Segura E,Vandamme E,Gavit P,Ehrlich HJ,Barrett PN,Baker DA

    更新日期:2012-04-01 00:00:00

  • Long-term production of pre-existing alloantibodies to E and c after allogenic BMT in a patient with aplastic anemia resulting in delayed hemolytic anemia.

    abstract:BACKGROUND:Delayed hemolysis mediated by long-term production of pre-existing recipient-derived antibodies directed against donor RBC antigens after allogenic BMT is an unusual complication of hematopoietic transplantation. CASE REPORT:A 26-year-old man with aplastic anemia had pre-existing alloantibodies to E and c. ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00303.x

    authors: Izumi N,Fuse I,Furukawa T,Uesugi Y,Tsuchiyama J,Toba K,Togashi K,Yamada K,Ohtake S,Saitoh Y,Yanagisawa N,Aizawa Y

    更新日期:2003-02-01 00:00:00

  • Granulocyte-colony-stimulatory factor: a strong inhibitor of natural killer cell function.

    abstract:BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02820.x

    authors: Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

    更新日期:2011-02-01 00:00:00

  • Considerations on the use of adjunct red blood cell exchange transfusion in the treatment of severe Plasmodium falciparum malaria.

    abstract:BACKGROUND:Travelers returning to the United States from malaria-endemic areas are at increased risk of a potentially fatal infection from Plasmodium falciparum, which requires prompt and aggressive treatment. STUDY DESIGN AND METHODS:Described is a case of a 7-year-old boy who was infected by P. falciparum while in A...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02530.x

    authors: Shelat SG,Lott JP,Braga MS

    更新日期:2010-04-01 00:00:00

  • Immunochemical studies on the differential binding properties of two monoclonal antibodies reacting with Tn red cells.

    abstract::Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31291142945.x

    authors: King MJ,Parsons SF,Wu AM,Jones N

    更新日期:1991-02-01 00:00:00

  • Hemoglobin thresholds for transfusion in pediatric patients at a large academic health center.

    abstract:BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13296

    authors: Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

    更新日期:2015-12-01 00:00:00

  • Absence of acute adverse in vitro effects on aged AS-1 red blood cells and thawed plasma after prolonged exposure to 13.56-MHz radio energy.

    abstract:BACKGROUND:There is growing interest in radio frequency identification (RFID) technology for tracking blood products to improve productivity and safety in the transfusion medicine supply chain. We conducted a limited study to assess the temperature and biologic effects after extreme exposure to 13.56-MHz RF radiation o...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03534.x

    authors: Davis R,Gottschall J,Gutierrez A,Hohberger C,Graminske S,Veeramani D,Holcombe J

    更新日期:2012-09-01 00:00:00

  • Successful storage of RBCs for 9 weeks in a new additive solution.

    abstract:BACKGROUND:This study explored the effect of storing packed RBCs suspended in 200 mL of an alkaline, hypotonic, experimental additive solution (EAS 61). STUDY DESIGN AND METHODS:Packed RBC units prepared from RBCs collected from healthy donors in CPD were stored for 8 (n = 10) and 9 (n = 10) weeks under blood bank con...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40081007.x

    authors: Hess JR,Rugg N,Knapp AD,Gormas JF,Silberstein EB,Greenwalt TJ

    更新日期:2000-08-01 00:00:00

  • Quantification of CD34+ cells: comparison of methods.

    abstract:BACKGROUND:Quantification of CD34+ stem and progenitor cells is predominantly performed by flow cytometric analysis of cells prepared by whole blood staining and red cell lysis. This method also includes cell washing, which is thought to cause the destruction and loss of some of the nucleated cells (NCs). To address th...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1997.37897424398.x

    authors: Fritsch G,Printz D,Stimpfl M,Dworzak MN,Witt V,Pötschger U,Buchinger P

    更新日期:1997-08-01 00:00:00

  • Semiautomated data analysis of flow cytometric estimation of fetomaternal hemorrhage in D- women.

    abstract:BACKGROUND:Accurate and reliable measurement of the volume of fetal D+ cells in D- women is required for adequate anti-D prophylaxis. A semiautomated flow cytometry assay based on a standardized calibration curve that was created with simulated fetomatemal hemorrhage (FMH) mixtures was developed. STUDY DESIGN AND METH...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00159.x

    authors: Greiss MA,Armstrong-Isher SS,Perera WS,Brown PM,Urbaniak SJ

    更新日期:2002-08-01 00:00:00

  • Incorporation of plasticizer into red cells during storage.

    abstract::The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1984.24685066808.x

    authors: Rock G,Tocchi M,Ganz PR,Tackaberry ES

    更新日期:1984-11-01 00:00:00

  • How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions.

    abstract::Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13015

    authors: Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

    更新日期:2015-06-01 00:00:00

  • Prevalence and quantitation of parvovirus B19 DNA levels in blood donors with a sensitive polymerase chain reaction screening assay.

    abstract:BACKGROUND:Blood donor parvovirus B19 DNA prevalence with sensitive nucleic acid test assays has recently been demonstrated to be higher than that found with assays designed to detect high viral titers in the plasma manufacturing sector. STUDY DESIGN AND METHODS:Stored plasma aliquots from 5020 donations collected bet...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01341.x

    authors: Kleinman SH,Glynn SA,Lee TH,Tobler L,Montalvo L,Todd D,Kiss JE,Shyamala V,Busch MP,National Heart, Lung, Blood Institute Retrovirus Epidemiology Donor Study (REDS-II).

    更新日期:2007-10-01 00:00:00

  • Implementation of a script for predonation interviews: impact on human immunodeficiency virus risk in South African blood donors.

    abstract:BACKGROUND:The way in which the donor history questionnaire is conducted plays a crucial role in the self-disclosure of behavioral risk factors for human immunodeficiency virus (HIV) infection by prospective donors. The South African National Blood Service changed its policy on the process of donor assessment in May 20...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15288

    authors: Mitchel J,Custer B,Kaidarova Z,Murphy EL,van den Berg K,Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) South Africa Program.

    更新日期:2019-07-01 00:00:00

  • Behavioral and infectious disease risks in young blood donors: implications for recruitment.

    abstract:BACKGROUND:Recruitment of young donors is critical to expand the donor base and sustain the blood supply. Nevertheless, there is concern that younger blood donors may have a higher risk profile than their older counterparts. STUDY DESIGN AND METHODS:The prevalence of behavioral risks associated with transfusion-transm...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00532.x

    authors: Damesyn MA,Glynn SA,Schreiber GB,Ownby HE,Bethel J,Fridey J,McMullen Q,Garratty G,Busch MP,NHLBI Retrovirus Epidemiology Donor Study.

    更新日期:2003-11-01 00:00:00

  • Spleen enlargement in healthy donors during G-CSF mobilization of PBPCs.

    abstract:BACKGROUND:Recombinant human G-CSF is widely used to mobilize PBPCs in healthy donors for allogeneic transplantation. There have been concerns about donor safety because of splenic ruptures during G-CSF application. To address this problem, changes in splenic size in 91 healthy donors during G-CSF mobilization of allog...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41020184.x

    authors: Platzbecker U,Prange-Krex G,Bornhäuser M,Koch R,Soucek S,Aikele P,Haack A,Haag C,Schuler U,Berndt A,Rutt C,Ehninger G,Hölig K

    更新日期:2001-02-01 00:00:00

  • Ammonia accumulation in platelet concentrates during storage.

    abstract::Newly prepared platelet concentrates (PC) and platelet poor plasma (PPP) stored at either room temperature (RT) or 4 C were analyzed for ammonia content initially, and after storage at 24, 48, and 72 hours. These studies demonstrate that ammonia rapidly accumulates in PC stored at RT. This accumulation appears to be t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:

    authors: Ukrainski CT,Goldfinger D,Pomerance JJ,Lee HC,Farber S,Sanchez R

    更新日期:1981-01-01 00:00:00

  • Anti-Rd (Radin) following the transfusion of a Radin positive unit of blood.

    abstract::Anti-Rd (Radin) was first described in association with five cases of hemolytic disease of the newborn. The authors report an anti-Rd that was demonstrated following the transfusion of a Radin positive unit of blood. The antibody appears to be of the IgG immunoglobulin class and increased in titer following the transf...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1976.16476247056.x

    authors: Winn LC,Eska PL,Grindon AJ

    更新日期:1976-07-01 00:00:00

  • Comparison of the analytical and operational performance of two viral nucleic acid test blood screening systems: Procleix Tigris and cobas s 201.

    abstract:BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01965.x

    authors: Assal A,Barlet V,Deschaseaux M,Dupont I,Gallian P,Guitton C,Morel P,David B,De Micco P

    更新日期:2009-02-01 00:00:00

  • Impact of rituximab on stem cell mobilization following ACVBP regimen in poor-risk patients with diffuse large B-cell lymphoma: results from a large cohort of patients.

    abstract:BACKGROUND:The ACVBP regimen is an efficient induction regimen for poor-risk patients with diffuse large B-cell lymphoma (DLBCL) before consolidative autologous stem cell transplantation. Adjunction of the monoclonal anti-CD20 antibody rituximab (R-ACVBP) was recently found to be superior to ACVBP alone. This study ass...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03683.x

    authors: Lefrère F,Bastit-Barrau D,Hequet O,Bourin P,Mathieu-Nafissi S,Bohbot A,Tilly H,Salles G,Fermé C,Lapierre V,Fornecker L,Micléa JM,Isebaert L,Bologna S,Fitoussi O,Mounier N,Haioun C

    更新日期:2013-01-01 00:00:00

  • Relationship of epitope glycosylation and other properties of blood group proteins to the immunogenicity of blood group antigens.

    abstract:BACKGROUND:The intrinsic properties of polypeptide blood group antigens that determine their relative immunogenicities are unknown. Because size, composition, charge, dose, and epitope glycosylation affect the immunogenicity of other polypeptides, we examined whether similar properties were related to the immunogenicit...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14609

    authors: Howe JG,Stack G

    更新日期:2018-07-01 00:00:00

  • Preoperative predictors of the need for allogeneic blood transfusion in lung cancer surgery.

    abstract:BACKGROUND:The use of blood-saving techniques in elective surgery can produce a favorable cost-benefit ratio only when there is a reasonable likelihood that transfusion will be required. To apply a targeted blood-sparing technique in lung cancer surgery, the patient's preoperative characteristics that predict the use o...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40101228.x

    authors: Cirasino L,Barosi G,Torre M,Crespi S,Colombo P,Belloni PA

    更新日期:2000-10-01 00:00:00

  • Nuclear matrix protein is released from apoptotic white cells during cold (1-6 degrees C) storage of concentrated red cell units and might induce antibody response in multiply transfused patients.

    abstract:BACKGROUND:A previous study showed that white cells in blood units undergo apoptosis during storage. STUDY DESIGN AND METHODS:The present study attempts to show the release of nuclear matrix protein (NMP) in the supernatants of red cell units and to determine whether antibodies against nuclear components may be presen...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40020169.x

    authors: Martelli AM,Tazzari PL,Bortul R,Riccio M,Tabellini G,Santi S,Frabetti F,Musiani D,Bareggi R,Conte R

    更新日期:2000-02-01 00:00:00

  • Neonatal alloimmune thrombocytopenia associated with maternal-fetal incompatibility for blood group B.

    abstract:BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01531.x

    authors: Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

    更新日期:2008-02-01 00:00:00