Abstract:
BACKGROUND:Information on the probability of survival of transfused patients is needed for policy making, but there is a paucity of empirical research into this question. A Swedish population-based study reported that the 40-month posttransfusion probability of survival was 51 percent in all patients and 41 percent in recipients of more than 10 units of blood and blood components. These figures were 20 percent lower than the figures reported previously from Olmsted County, Minnesota. STUDY DESIGN AND METHODS:Information was collected on the 4-year survival of 695 patients transfused at the New York University Medical Center between 1988 and 1996. These patients had been identified previously by hepatitis C lookback. RESULTS:Seventy-five percent of patients survived at 1 month after transfusion, 66 percent at 3 months, 60 percent at 6 months, 54 percent at 1 year, 50 percent at 2 years, 45 percent at 3 years, and 41 percent at 4 years. Seventy-eight percent of patients included in the study had received more than 10 units of blood and blood components. The 4-year survival of patients receiving 1 to 3, 4 to 10, or more than 10 units was 62 percent, 48 percent, and 38 percent, respectively (p < 0.0001). CONCLUSIONS:When transfusion dose is taken into account, the probability of survival of patients transfused at the New York University Medical Center in 1988 to 1996 and identified by lookback is similar to that reported for Swedish county residents transfused in 1993. Based on both the Swedish data and the information presented here and in the absence of any recent results from population-based studies, the survival of U.S. patients transfused in the 1990s appears to be 20 percent lower than that of Olmsted County residents transfused in 1981.
journal_name
Transfusionjournal_title
Transfusionauthors
Vamvakas EC,Goldstein Rdoi
10.1046/j.1537-2995.2002.00109.xsubject
Has Abstractpub_date
2002-06-01 00:00:00pages
691-7issue
6eissn
0041-1132issn
1537-2995pii
trf109journal_volume
42pub_type
杂志文章相关文献
TRANSFUSION文献大全abstract::The serum of a pregnant woman whose red cells typed as Co(a-b-) contained an alloantibody that, at the time of the infants delivery, was hemolytic in vitro and had a titer of 32,000 by the antiglobulin test. This antibody, which reacted with cells of all Colton-phenotypes except the proposita's own cells, showed very ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1987.27387235637.x
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Drug-induced immune thrombocytopenia (DITP) is a serious, life-threatening clinical syndrome, the diagnosis of which is consistently difficult. In this report, we present a case of DITP caused by meropenem that was confirmed by laboratory tests. CASE REPORT:A 59-year-old male patient developed severe thromb...
journal_title:Transfusion
pub_type:
doi:10.1111/trf.14267
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1994.34294143949.x
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Supply of cytomegalovirus (CMV)-seronegative blood products in Australia is an ongoing challenge. Requests for CMV-negative products are increasing with prediction that the demand will exceed supply by 2019. Clinical information evaluating how these products are being utilized by health providers within Aust...
journal_title:Transfusion
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/trf.14459
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Used leuko-depletion filters (LDFs), containing billions of white blood cells (WBCs), are discarded. Because the steady-state blood contains low quantities of stem and progenitor cells that are retained in LDFs, the viability and the functional properties of mononuclear cells (MNCs) and CD 34+ cells recovere...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2005.00677.x
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Most alloantigens on transfused red blood cells (RBCs) are weakly immunogenic, with only a 2 to 6 percent overall immunization rate even in patients receiving multiple transfusions. Although recipient genetics may contribute to responder and/or nonresponder status, in most cases HLA type does not predict hum...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2006.00946.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:The recent H1N1 pandemic provided an opportunity to conceptually assess the possibility of rapidly providing a "hyperimmune" human immunoglobulin (H-IVIG) to an emerging infectious disease, in useful quantities with respect to public health. Commercial-scale H-IVIG production from plasma collected from donor...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2011.03347.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Delayed hemolysis mediated by long-term production of pre-existing recipient-derived antibodies directed against donor RBC antigens after allogenic BMT is an unusual complication of hematopoietic transplantation. CASE REPORT:A 26-year-old man with aplastic anemia had pre-existing alloantibodies to E and c. ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2003.00303.x
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2010.02820.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Travelers returning to the United States from malaria-endemic areas are at increased risk of a potentially fatal infection from Plasmodium falciparum, which requires prompt and aggressive treatment. STUDY DESIGN AND METHODS:Described is a case of a 7-year-old boy who was infected by P. falciparum while in A...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2009.02530.x
更新日期:2010-04-01 00:00:00
abstract::Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1991.31291142945.x
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13296
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:There is growing interest in radio frequency identification (RFID) technology for tracking blood products to improve productivity and safety in the transfusion medicine supply chain. We conducted a limited study to assess the temperature and biologic effects after extreme exposure to 13.56-MHz RF radiation o...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2011.03534.x
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:This study explored the effect of storing packed RBCs suspended in 200 mL of an alkaline, hypotonic, experimental additive solution (EAS 61). STUDY DESIGN AND METHODS:Packed RBC units prepared from RBCs collected from healthy donors in CPD were stored for 8 (n = 10) and 9 (n = 10) weeks under blood bank con...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2000.40081007.x
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Quantification of CD34+ stem and progenitor cells is predominantly performed by flow cytometric analysis of cells prepared by whole blood staining and red cell lysis. This method also includes cell washing, which is thought to cause the destruction and loss of some of the nucleated cells (NCs). To address th...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1997.37897424398.x
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Accurate and reliable measurement of the volume of fetal D+ cells in D- women is required for adequate anti-D prophylaxis. A semiautomated flow cytometry assay based on a standardized calibration curve that was created with simulated fetomatemal hemorrhage (FMH) mixtures was developed. STUDY DESIGN AND METH...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2002.00159.x
更新日期:2002-08-01 00:00:00
abstract::The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1984.24685066808.x
更新日期:1984-11-01 00:00:00
abstract::Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13015
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Blood donor parvovirus B19 DNA prevalence with sensitive nucleic acid test assays has recently been demonstrated to be higher than that found with assays designed to detect high viral titers in the plasma manufacturing sector. STUDY DESIGN AND METHODS:Stored plasma aliquots from 5020 donations collected bet...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2007.01341.x
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:The way in which the donor history questionnaire is conducted plays a crucial role in the self-disclosure of behavioral risk factors for human immunodeficiency virus (HIV) infection by prospective donors. The South African National Blood Service changed its policy on the process of donor assessment in May 20...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.15288
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Recruitment of young donors is critical to expand the donor base and sustain the blood supply. Nevertheless, there is concern that younger blood donors may have a higher risk profile than their older counterparts. STUDY DESIGN AND METHODS:The prevalence of behavioral risks associated with transfusion-transm...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2003.00532.x
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Recombinant human G-CSF is widely used to mobilize PBPCs in healthy donors for allogeneic transplantation. There have been concerns about donor safety because of splenic ruptures during G-CSF application. To address this problem, changes in splenic size in 91 healthy donors during G-CSF mobilization of allog...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2001.41020184.x
更新日期:2001-02-01 00:00:00
abstract::Newly prepared platelet concentrates (PC) and platelet poor plasma (PPP) stored at either room temperature (RT) or 4 C were analyzed for ammonia content initially, and after storage at 24, 48, and 72 hours. These studies demonstrate that ammonia rapidly accumulates in PC stored at RT. This accumulation appears to be t...
journal_title:Transfusion
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Anti-Rd (Radin) was first described in association with five cases of hemolytic disease of the newborn. The authors report an anti-Rd that was demonstrated following the transfusion of a Radin positive unit of blood. The antibody appears to be of the IgG immunoglobulin class and increased in titer following the transf...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1976.16476247056.x
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2008.01965.x
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:The ACVBP regimen is an efficient induction regimen for poor-risk patients with diffuse large B-cell lymphoma (DLBCL) before consolidative autologous stem cell transplantation. Adjunction of the monoclonal anti-CD20 antibody rituximab (R-ACVBP) was recently found to be superior to ACVBP alone. This study ass...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2012.03683.x
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The intrinsic properties of polypeptide blood group antigens that determine their relative immunogenicities are unknown. Because size, composition, charge, dose, and epitope glycosylation affect the immunogenicity of other polypeptides, we examined whether similar properties were related to the immunogenicit...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.14609
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:The use of blood-saving techniques in elective surgery can produce a favorable cost-benefit ratio only when there is a reasonable likelihood that transfusion will be required. To apply a targeted blood-sparing technique in lung cancer surgery, the patient's preoperative characteristics that predict the use o...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2000.40101228.x
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:A previous study showed that white cells in blood units undergo apoptosis during storage. STUDY DESIGN AND METHODS:The present study attempts to show the release of nuclear matrix protein (NMP) in the supernatants of red cell units and to determine whether antibodies against nuclear components may be presen...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2000.40020169.x
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2007.01531.x
更新日期:2008-02-01 00:00:00