How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions.

abstract：BACKGROUND:The experience of unpleasant blood donation reactions (e.g., dizziness, nausea, and fainting) has been linked to negative attitudes about donation and decreased likelihood of repeat donation. Consequently, interventions to reduce the adverse effects of blood donation are important and likely to increase dono...

journal_title：Transfusion

authors： Hanson SA,France CR

更新日期：2009-05-01 00:00:00

abstract：:A unit-dose system was designed to dispense precise quantities of blood in a form ready for immediate transfusion into neonatal patients. The principles were similar to those used by pharmacies to dispense individual doses of drugs. In the blood center, the precise volume of blood ordered for a neonatal patient was as...

journal_title：Transfusion

authors： Strauss RG,Crawford GF,Elbert C,Floss AM,Liesch M

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:The writings of the 17th and 19th centuries about experiments and debates about transfusion were often analyzed and discussed in articles and books, but an analysis of illustrations of transfusion during this pioneering epoch can throw new light on the subject. The first transfusion attempts were as sensatio...

journal_title：Transfusion

authors： Lefrère JJ,Danic B

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Data on red blood cell (RBC) transfusion in the United States show variation in practice and overprescribing or overdosing is considered to be prevalent. Education or restrictive interventions could modify practice. STUDY DESIGN AND METHODS:RBC transfusion and mortality rates were recorded in a single insti...

journal_title：Transfusion

authors： Tavares MM,Diquattro PJ,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Storage age of red blood cells (RBCs) has been reported to be associated with increased mortality and morbidity. During storage, RBCs undergo changes in biochemical and functional properties. Stored RBCs may also contain white blood cells (WBCs), activated platelets (PLTs), cytokines, immunoglobulin, and oth...

journal_title：Transfusion

authors： Sowemimo-Coker SO

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:RBCs modified with cyanuric chloride activated methoxy-PEG (CmPEG; 5000 Da) are less immunogenic than untreated RBCs, and their use thus may reduce the risk of alloimmunization in chronically transfused patients. STUDY DESIGN AND METHODS:To further examine the potential utility of CmPEG-RBCs, the effects of...

journal_title：Transfusion

authors： Bradley AJ,Test ST,Murad KL,Mitsuyoshi J,Scott MD

更新日期：2001-10-01 00:00:00

abstract：:Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although dono...

journal_title：Transfusion

authors： Grossman BJ,Stewart NC,Grindon AJ

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

journal_title：Transfusion

authors： Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The AABB Clinical Transfusion Medicine Committee (CTMC) compiles an annual synopsis of the published literature covering important developments in the field of transfusion medicine (TM) for the board of director's review. This synopsis is now made available as a manuscript published in TRANSFUSION. STUDY DE...

journal_title：Transfusion

authors： Pagano MB,Allen ES,Chou ST,Dunbar NM,Gniadek T,Goel R,Harm SK,Hopkins CK,Jacobson J,Lokhandwala PM,Metcalf RA,Raval JS,Schwartz J,Shan H,Spinella PC,Storch E,Cohn CS

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Reports of Monosomy 7 in patients receiving granulocyte-colony-stimulating factor (G-CSF) have raised concerns that this cytokine may promote genomic instability. However, there are no studies addressing whether repeated administration of G-CSF produces Monosomy 7 aneuploidy in healthy donors. STUDY DESIGN ...

journal_title：Transfusion

authors： Olnes MJ,Poon A,Miranda SJ,Pfannes L,Tucker Z,Loeliger K,Padilla-Nash H,Yau YY,Ried T,Leitman SF,Young NS,Sloand EM

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The addition of an appropriate metal chelator, such as diethylenetriaminopentaacetic acid (DTPA) to stored blood has been shown to be effective in a short-term (0-12 days) prevention of lipid peroxidation of stored RBCS: However, its long-term effectiveness has not been carefully evaluated. STUDY DESIGN AND...

journal_title：Transfusion

authors： Liu TZ,Chiu DT,Stern A

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect. STUDY DESIGN AND METHODS:The concentration of BK and one of its vasoactive metabolites, des-arginine(9)-BK (des-Arg(9)...

journal_title：Transfusion

authors： Moreau ME,Thibault L,Désormeaux A,Chagnon M,Lemieux R,Robillard P,Marceau F,Colman RW,Lepage Y,Rivard GE,Adam A

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) product wastage in hospitals is reported to range from 0.1% to 6.7%. Wastage at our institution averaged 4.4% of 63,000 issued RBC products. Data indicated that approximately 87% of wasted RBC units were either individual units that were out of blood bank for more than 30 minutes (dispen...

journal_title：Transfusion

authors： Heitmiller ES,Hill RB,Marshall CE,Parsons BJ,Berkow LC,Barrasso CA,Zink EK,Ness PM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Erythrocytapheresis (ECP), automated red blood cell exchange, is increasingly being used for chronic transfusion therapy in sickle cell disease (SCD) as it is an isovolumetric transfusion, is more effective in lowering hemoglobin (Hb)S, and can limit iron overload. Because ECP requires increased blood exposu...

journal_title：Transfusion

authors： Wahl SK,Garcia A,Hagar W,Gildengorin G,Quirolo K,Vichinsky E

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The term platelet storage lesion (PSL) describes the structural and biochemical changes in platelets (PLTs) during storage. These are typified by alterations of morphologic features and PLT metabolism leading to reduced functionality and hence reduced viability for transfusion. While the manifestations of th...

journal_title：Transfusion

authors： Schubert P,Thon JN,Walsh GM,Chen CH,Moore ED,Devine DV,Kast J

更新日期：2009-09-01 00:00:00

abstract：:Extracellular vesicles (EVs) are small, subcellular vesicles that are released from a variety of cells and play important roles in cell-to-cell communication. Transfused blood products, including red blood cell, platelet, and plasma products contain EVs that are capable of interacting with and altering immune cell fun...

journal_title：Transfusion

authors： Menocha S,Muszynski JA

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Recent blood shortages and the potential clinical impact of red blood cell (RBC) age highlight the need to understand blood supply delivery. This study addresses the characteristics and mechanics of RBC unit trafficking and storage across the transfusion service, previously undescribed in the literature. ST...

journal_title：Transfusion

authors： Cheng CK,Trethewey D,Sadek I

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Cryopreserved umbilical cord blood (CB) is increasingly used as a cell source to reconstitute marrow in hematopoietic stem cell transplant patients. Delays in cryopreservation may adversely affect cell viability, thereby reducing their potential for engraftment after transplantation. STUDY DESIGN AND METHOD...

journal_title：Transfusion

authors： Guttridge MG,Soh TG,Belfield H,Sidders C,Watt SM

更新日期：2014-05-01 00:00:00

abstract：:We have estimated the risk of transmitting HIV infection from a unit of HIV seronegative blood collected in Los Angeles and Orange Counties, CA from March 1985 through February 1987. Our method consisted of lookback investigations and anti-HIV testing of living recipients of HIV seronegative units donated by persons w...

journal_title：Transfusion

authors： Kleinman S,Secord K

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is the most common cause of death from blood transfusion and red blood cells (RBCs) now account for approximately 50% of these fatalities. RBCs from female donors have been implicated in large series and HLA Class II antibodies to cognate recipient antigens ident...

journal_title：Transfusion

authors： Weber LL,Roberts LD,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：:The transfusion of red cells (RBCs) was analyzed over a 4-year period (1984-1987), during which 9596 cesarean deliveries were performed. A total of 336 patients were identified as receiving RBC transfusions during or after cesarean delivery; 747 units of RBCs were administered. The overall incidence of transfusion in ...

journal_title：Transfusion

authors： Camann WR,Datta S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Previous studies showed that Mirasol (Navigant Biotechnologies, Inc.) pathogen reduction technology (PRT) treatment resulted in an increase in platelet (PLT) glucose consumption and lactate production rates and decrease in pH in media during PLT storage. Increased glycolytic flux could result from damage to ...

journal_title：Transfusion

authors： Li J,Lockerbie O,de Korte D,Rice J,McLean R,Goodrich RP

更新日期：2005-06-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The use of a platelet additive solution (PAS-II, Baxter) may have benefits over plasma for storage of platelets. It was the aim of this study to develop a method to produce WBC-reduced platelet concentrates (PCs) in PAS-II with >240 x 10(9) platelets and <1 x 10(6) WBCs per unit, which can be stored for 5 da...

journal_title：Transfusion

authors： van der Meer PF,Pietersz RN,Tiekstra MJ,Huijgens PC,Dekker WJ,Reesink HW

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The greatest limiting factor in the use of umbilical cord blood (UCB) for transplantations is the number of stem cells available in any given collected unit. This study examines maternal, neonatal, and obstetric factors that influence the suitability for banking and transplantation of UCB units collected in ...

journal_title：Transfusion

authors： Keersmaekers CL,Mason BA,Keersmaekers J,Ponzini M,Mlynarek RA

更新日期：2014-03-01 00:00:00

abstract：:Alloagglutinins of M and N specificites with unique characteristics found in normal sera are described. Specific M or N agglutination by these sera occurred only when erythrocytes had been exposed to glucose-containing solutions. Conversion to the form of MN recognized by these sera required incubation of the cells in...

journal_title：Transfusion

authors： Morel PA,Bergren MO,Hill V,Garratty G,Perkins HA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:The risk of transfusion reactions (TR) and the cost of blood has led to efforts to reduce blood use. We changed our practice to transfuse just one instead of two units of red blood cells (RBC) when hemoglobin ≤8 g/dL due to patient blood management (PBM) recommendations. METHODS AND MATERIALS:We compared RB...

journal_title：Transfusion

authors： Gastecki K,Shanley R,Welbig J,Cohn C,Brunstein CG

更新日期：2019-07-01 00:00:00