Transfusion-related immune modulation: functional consequence of extracellular vesicles?

abstract：:Dimethyl sulfoxide (DMSO) is used as a cryoprotective agent when platelets are frozen. We examined the effect of DMSO (0.1 to 10%) on platelet aggregation, release, and prostaglandin synthesis (as indicated by malondialdehyde formation) in response to thrombin, collagen, arachidonic acid and calcium ionophore. Inhibit...

journal_title：Transfusion

authors： Fratantoni JC,Poindexter BJ

更新日期：1983-03-01 00:00:00

abstract：:The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and c...

journal_title：Transfusion

authors： Rydberg L,Breimer ME,Samuelsson BE

更新日期：1988-09-01 00:00:00

abstract：:Monitoring of platelet counts 1 hour after transfusion has become standard practice in most centers. In this study, platelet counts obtained 10 and 60 minutes after 48 platelet transfusions were compared. There was a close, linear relationship (r = 0.98) between these values over a wide range of posttransfusion counts...

journal_title：Transfusion

authors： O'Connell B,Lee EJ,Schiffer CA

更新日期：1988-01-01 00:00:00

abstract：:Many significant events have occurred in the recent past that beg a broad audience to address the question "What is pediatric transfusion medicine?" Herein, we list some of these events and their relevance below and attempt to provide an answer for this question. Indeed, several issues regarding the subspecialty of pe...

journal_title：Transfusion

authors： Hillyer CD,Mondoro TH,Josephson CD,Sanchez R,Sloan SR,Ambruso DR

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:A high-throughput detection system was developed for HBV DNA and HCV RNA. METHODS:A combination of real-time detection PCR using an automated system (PRISM 7700, PE Biosystems, Foster City, CA) and automatic viral nucleic acid extraction (BioRobot 9604, Qiagen, Hilden, Germany) was used as the high-throughp...

journal_title：Transfusion

authors： Mitsunaga S,Fujimura K,Matsumoto C,Shiozawa R,Hirakawa S,Nakajima K,Tadokoro K,Juji T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Intravenous immunoglobulin G (IVIG) replacement therapy is used to prevent invasive infections in patients with primary antibody deficiency (PAD). However, few studies have functionally evaluated specific antibodies against encapsulated bacteria that cause invasive infection in patients with PAD. In this stu...

journal_title：Transfusion

authors： Lee S,Kim HW,Kim KH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Direct oral anticoagulants (DOACs) are effective and safe for prophylaxis and treatment of thromboembolic phenomena. However, managing DOACs during bleeding emergencies is challenging. A systematic review and meta-analysis was conducted on studies addressing efficacy and safety of the drugs used for reversal...

journal_title：Transfusion

authors： da Luz LT,Marchand M,Nascimento B,Tien H,Nathens A,Shah P

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Since screening for antibody to hepatitis C virus (HCV) was introduced in 1990, posttransfusion hepatitis has been reduced to nearly background levels. This has led to reconsideration of the value of testing donated blood for elevated alanine aminotransferase (ALT). The contribution of ALT testing in detecti...

journal_title：Transfusion

authors： Sankary TM,Yang G,Romeo JM,Ulrich PP,Busch MP,Rawal BD,Vyas GN

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:At most US blood centers, patients may still opt to choose specific donors to give blood for their anticipated transfusion needs. However, there is little evidence of improved safety with directed donation when compared to volunteer donation. STUDY DESIGN AND METHODS:The percentage of directed donations mad...

journal_title：Transfusion

authors： Dorsey KA,Moritz ED,Steele WR,Eder AF,Stramer SL

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Much effort and resources have been devoted to programs that provide transfusion support for patients with sickle cell disease (SCD). The focus of many donor programs is to prevent alloimmunization by recruiting racially matched African American donors to limit the red blood cell (RBC) antigenic differences ...

journal_title：Transfusion

authors： Karafin MS,Field JJ,Gottschall JL,Denomme GA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The 2016 Food and Drug Administration draft guidance describes the use of a rapid test (RT) to enhance platelet transfusion safety and availability. This study reports a 113-month experience of screening of apheresis platelets (APs) by RT. STUDY DESIGN AND METHODS:From July 2008 to October 2015, all APs und...

journal_title：Transfusion

authors： Ruby KN,Thomasson RR,Szczepiorkowski ZM,Dunbar NM

更新日期：2018-07-01 00:00:00

abstract：:The accumulation of the plasticizer di-2-ethylhexylphthalate (DEHP) in blood and blood components has been of considerable concern for some time. We have followed the accumulation of DEHP and one of its major metabolities, mono-2-ethylhexylphthalate (MEHP) during storage of whole blood, platelet-rich plasma, platelet ...

journal_title：Transfusion

authors： Rock G,Secours VE,Franklin CA,Chu I,Villeneuve DC

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

journal_title：Transfusion

authors： Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：:Donor deferral rates in regional blood centers vary from 5 to 24 per cent, reducing by more than 1,250,000 the number of units of volunteer blood available for transfusion in the nation each year. Those criteria for donor deferral which are intended to exclude donors likely to suffer a "donor reaction" are based parti...

journal_title：Transfusion

authors： Tomasulo PA,Anderson AJ,Paluso MB,Gutschenritter MA,Aster RH

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

journal_title：Transfusion

authors： Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Transfusion-associated microchimerism (TA-MC), the persistence of significant levels of donor white blood cells (WBCs) in blood recipients for prolonged periods, has been demonstrated after nonleukoreduced and leukoreduced transfusion to patients with severe traumatic injury. Development of TA-MC has not bee...

journal_title：Transfusion

authors： Sanchez R,Lee TH,Wen L,Montalvo L,Schechterly C,Colvin C,Alter HJ,Luban NL,Busch MP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The HCV lookback program was designed to trace and offer testing to recipients who received transfusion of blood components from donors subsequently found to be anti-HCV positive. Only approximately 20 percent of transfusable components entering lookback did result in a recipient obtaining testing through th...

journal_title：Transfusion

authors：

更新日期：2002-09-01 00:00:00

abstract：:The purpose of this study was to ascertain the cause for seasonal variations of donor deferral. Deferred donors and monthly temperatures from 1981 to 1984 were tallied and analyzed. Temperatures were categorized at 10-degree intervals from 15 degrees F to 75 degrees F. Donors failing the hemoglobin screening then unde...

journal_title：Transfusion

authors： Lau P,Hansen M,Sererat M

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：:Several blood transfusion filters designed to remove microemboli were evaluated for filtration and flow characteristics, as well as for hemolysis and for release of particulate debris from the filter. The Dacron wool filter, a depth filter, was superior at removing microemboli measured with an electronic particle size...

journal_title：Transfusion

authors： Kennedy PS,Solis RT,Scott MA,Wilson RK

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization occurs at a high frequency in sickle cell anemia (SCA) despite serologic matching for Rh (C/c, E/e) and K antigens. RBC minor antigen genotyping allows for prediction of antigens and RH variants that may lead to alloimmunization. STUDY DESIGN AND METHODS:RBC antigen gen...

journal_title：Transfusion

authors： Yee MEM,Josephson CD,Winkler AM,Webb J,Luban NLC,Leong T,Stowell SR,Fasano RM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Preoperative autologous blood donation (PABD) has been used to reduce the need for allogeneic RBC transfusion, decreasing risk and conserving supply. A frozen PABD program for heart transplant patients was instituted at the Mayo Clinic in 1988, but participation has steadily declined. The aims of this study ...

journal_title：Transfusion

authors： Fontaine MJ,Winters JL,Moore SB,McGregor CG,Santrach PJ

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:For patients with thrombocytopenia without bleeding risk factors, a platelet transfusion trigger of 10 × 10(9) /L is recommended. No studies have evaluated the clinicians' decision-making process leading to trigger changes. STUDY DESIGN AND METHODS:We report on the evaluation of trigger changes and the rela...

journal_title：Transfusion

authors： Rioux-Massé B,Laroche V,Bowman RJ,Lindgren BR,Cohn CS,Pulkrabek SM,McCullough J

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Deterioration in quality of platelet concentrates (PCs) during storage results from the appearance of storage lesions affecting the hemostatic functions and posttransfusion survival of platelets. These lesions depend on the preparation and pathogen inactivation methods used, duration of storage, and platelet...

journal_title：Transfusion

authors： Isola H,Ravanat C,Rudwill F,Pongerard A,Haas D,Eckly A,Gachet C,Hechler B

更新日期：2021-02-01 00:00:00

abstract：:Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

journal_title：Transfusion

authors： Maegele M

更新日期：2013-01-01 00:00:00

abstract：:The potassium load of transfused blood must be minimized. We have compared the total plasma potassium content of units of CPD-preserved stored whole blood (SWB), stored packed cells (SPC), and packed cells prepared from stored whole blood (WB-PC). Plasma potassium concentrations, unit weights, and hematocrits of 20 un...

journal_title：Transfusion

authors： Michael JM,Dorner I,Bruns D,Ladenson JH,Sherman LA

更新日期：1975-03-01 00:00:00

abstract：:The two-stage method of Pool and Robinson was used in determining plasma Factor VIII activity following contact with four commercially available plastic blood and pooling bag films. Employing a two-arm double plasmapheresis technique, it was shown that Factor VIII activity in whole blood initially drawn into BB-69 and...

journal_title：Transfusion

authors： Mishler JM,Nicora RW,Hamilton JE,Caster G,Kasper CK

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:By regulation, ongoing process control of WBC-reduced processes is performed on 1 percent of WBC-reduced components, typically four to five samples per month. However, prospective study of the power of this small sample has been difficult. Using computer-generated "residual WBC" distributions, sample size se...

journal_title：Transfusion

authors： Adams MR,Fisher DM,Dumont LJ,Dzik WH,Heaton WA

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

journal_title：Transfusion

authors： Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

更新日期：2011-02-01 00:00:00