Frozen preoperative autologous blood donation for heart transplantation at the Mayo Clinic from 1988 to 1999.

Abstract:

BACKGROUND:Preoperative autologous blood donation (PABD) has been used to reduce the need for allogeneic RBC transfusion, decreasing risk and conserving supply. A frozen PABD program for heart transplant patients was instituted at the Mayo Clinic in 1988, but participation has steadily declined. The aims of this study were to determine how the availability of PABD influenced the transfusion RBC components, whether the availability of PABD reduced exposure to allogeneic RBC components, and the costs of providing PABD units. STUDY DESIGN AND METHODS:A retrospective review of all heart transplant cases from 1988 to 1999 was performed (n = 141). Data on collection and transfusion practices were compared for patients with (n = 88, 62%) and without PABD (n = 53, 38%). RESULTS:Total RBC transfusion requirements did not differ between the groups. Patients with frozen PABD received fewer allogeneic units, but they also had less blood salvaged and reinfused. Twenty patients (23%) completely avoided exposure to allogeneic RBCs in the PABD group versus three patients (6%) in the group without PABD. Although patients in the PABD group successfully donated a total of 423 units, 41 percent were discarded. Over 11 years, the need for 251 units of allogeneic RBCs was avoided ($27,610), but $283,500 was spent to have the frozen PABD units available. CONCLUSION:PABD can be performed for heart transplantation, but it is expensive.

journal_name

Transfusion

journal_title

Transfusion

authors

Fontaine MJ,Winters JL,Moore SB,McGregor CG,Santrach PJ

doi

10.1046/j.1537-2995.2003.00357.x

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

476-80

issue

4

eissn

0041-1132

issn

1537-2995

pii

trf357

journal_volume

43

pub_type

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