Platelet storage in a plasma-free medium.

abstract：:Seven hundred and sixty-three blood donors previously typed for HLA-A and B antigens were asked to consider donating bone marrow to unrelated patients for whom no HLA-matched sibling was available. Eighty-eight percent (668) indicated willingness to donate marrow, and of these, 615 (81%) participated in testing and 53...

journal_title：Transfusion

authors： McElligott MC,Menitove JE,Aster RH

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:A new automated apheresis system has recently been reported as useful in improving peripheral blood HPC collection in adults. The aim of this study has been to verify the utility of this system (AutoPBSC, COBE BCT) for standard leukapheresis and for LVL in the pediatric setting. STUDY DESIGN AND METHODS:A p...

journal_title：Transfusion

authors： Torrabadella M,Olivé T,Ortega JJ,Massuet L

更新日期：2000-04-01 00:00:00

abstract：:Standard packed red cell (PRC) units can be depleted of leukocytes and platelets if they are transfused through a blood administration set in which the usual 170-mu filter has been replaced by a leukocyte removal filter (Sepacell R-500). During a 6-month period, 1550 PRC units were transfused through this filter in 61...

journal_title：Transfusion

authors： Sirchia G,Rebulla P,Parravicini A,Carnelli V,Gianotti GA,Bertolini F

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:AABB Standard 5.27 requires transfusion services to have a process for urgent release of blood before completion of compatibility testing. Our institution endorses a policy for the emergency release of group O, D+ red blood cells (RBC; O+ RBC) to males and females at least 50 years of age. Our emergency depa...

journal_title：Transfusion

authors： Meyer E,Uhl L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Allogeneic blood cell transplantation is a new alternative to bone marrow transplantation. Preliminary data suggest that granulocyte-colony-stimulating factor (G-CSF)-mobilized peripheral blood progenitor cells from normal donors can provide rapid hematopoietic engraftment without significant increases in tr...

journal_title：Transfusion

authors： Weinthal JA,Nemunaitis JJ,Aston S,Magsamen MJ,Rosenfeld CS

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The proposal to assess the viability capabilities of platelets (PLTs) collected, treated, or stored in a developmental system against "fresh" PLTs from the same subject poses several important methodologic issues pertaining to the timing and manner of the collecting and separating the fresh PLTs. This study ...

journal_title：Transfusion

authors： AuBuchon JP,Herschel L,Roger J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:An optimal cooling rate is critical for cryopreserving cord blood stem cells, so it is generally achieved by using controlled-rate freezers (CRFs). The cooling rate can be interrupted by many factors during cooling; therefore, a proper response to the interruption in cryopreservation is crucial to prevent th...

journal_title：Transfusion

authors： Yang H,Pidgorna A,Loutfy MR,Shuen P

更新日期：2015-01-01 00:00:00

abstract：:Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward. ...

journal_title：Transfusion

authors： Daniels GL,Judd WJ,Moore BP,Neitzer G,Ouellet P,Plantos M,Verrette S

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Interventions intended to motivate donors to return can be costly and time consuming. The current study examined the effect of a Web-based automated interview, informed by motivational interviewing and self-determination theory, on donor intention, motivation, and behavior in a sample of highly experienced d...

journal_title：Transfusion

authors： Livitz IE,France CR,France JL,Fox KR,Ankawi B,Slepian PM,Kessler DA,Rebosa M,Shaz BH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Tissue hypoxia and reperfusion induce abnormal hemostatic function. Therefore, bleeding after total knee replacement (TKR) may be a result of a tourniquet-induced imbalance of the procoagulant and fibrinolytic systems. Because laboratory confirmation of tourniquet-induced abnormal hemostasis is difficult to ...

journal_title：Transfusion

authors： Zohar E,Fredman B,Ellis MH,Ifrach N,Stern A,Jedeikin R

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:A high-throughput detection system was developed for HBV DNA and HCV RNA. METHODS:A combination of real-time detection PCR using an automated system (PRISM 7700, PE Biosystems, Foster City, CA) and automatic viral nucleic acid extraction (BioRobot 9604, Qiagen, Hilden, Germany) was used as the high-throughp...

journal_title：Transfusion

authors： Mitsunaga S,Fujimura K,Matsumoto C,Shiozawa R,Hirakawa S,Nakajima K,Tadokoro K,Juji T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Transfusion of platelet concentrates (PCs) is the basic treatment for severe platelet disorders. PCs carry the risk of pathogen transmission, especially bacteria. Pathogen reduction (PR) by addition of photochemical reagents and irradiation with visible or ultraviolet (UV) light can significantly reduce this...

journal_title：Transfusion

authors： Mohr H,Steil L,Gravemann U,Thiele T,Hammer E,Greinacher A,Müller TH,Völker U

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Deferasirox (DFRA) is a new approved oral iron chelator. Its advantages are that it is convenient and better tolerated and adhered to due to "once-daily" oral dosage. However, its use in the field is limited and it is yet to be subjected to postmarketing surveillance. CASE REPORT:A 18.75-year-old male with ...

journal_title：Transfusion

authors： Wei HY,Yang CP,Cheng CH,Lo FS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The Q fever outbreaks in the Netherlands in 2007 to 2009 initiated discussion on the necessity of measures to prevent transmission through blood products. Risk assessments help transfusion regulators decide when and where measures are required. This study assesses the transfusion transmission (TT) risk of Q ...

journal_title：Transfusion

authors： Oei W,Kretzschmar ME,Zaaijer HL,Coutinho R,van der Poel CL,Janssen MP

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：:Anti-Hy, in a serum of a black man who had received multiple blood transfusions, was found to be a warm reactive and polyclonal IgG antibody which did not bind complement in vitro. 51Cr-labeled Hy-positive red blood cells in the patient showed a shortened "2-component" survival curve. Hy antigens were not detected on ...

journal_title：Transfusion

authors： Hsu TC,Jagathambal K,Sabo BH,Sawitsky A

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:In 2009 the Mirasol Pathogen Reduction Technology (PRT) was introduced to the routine blood component production of the Regional Blood Transfusion Center in Warsaw (RBTCW). The goal of this study was to investigate the safety of Mirasol-treated blood components. STUDY DESIGN AND METHODS:The accumulated pass...

journal_title：Transfusion

authors： Łętowska M,Przybylska Z,Piotrowski D,Lachert E,Rosiek A,Rzymkiewicz L,Cardoso M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:For patients with thrombocytopenia without bleeding risk factors, a platelet transfusion trigger of 10 × 10(9) /L is recommended. No studies have evaluated the clinicians' decision-making process leading to trigger changes. STUDY DESIGN AND METHODS:We report on the evaluation of trigger changes and the rela...

journal_title：Transfusion

authors： Rioux-Massé B,Laroche V,Bowman RJ,Lindgren BR,Cohn CS,Pulkrabek SM,McCullough J

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Red blood cells (RBCs) undergo changes during storage. Various studies have suggested a higher risk of adverse and often multifactorial clinical outcomes associated with older-stored RBCs. Our aim therefore was to examine if storage of transfused RBCs is also associated with the risk of RBC-specific alloanti...

journal_title：Transfusion

authors： Zalpuri S,Schonewille H,Middelburg R,van de Watering L,de Vooght K,Zimring J,van der Bom JG,Zwaginga JJ

更新日期：2013-11-01 00:00:00

abstract：:Antiglobulin sera from nine different manufacturers have been tested, over a two-year period, for their ability to detect the complement components beta 1A, alpha 2D, and beta 1E. The results demontrate considerable variation in the abilities of sera from different manufacturers to detect these components and indicate...

journal_title：Transfusion

authors： Issitt PD,Issitt CH,Wilkinson SL

更新日期：1974-03-01 00:00:00

abstract：BACKGROUND:The major cause of fetal hemolytic disease is maternal immunization to D in D-incompatible pregnancies. To prevent complications, D-incompatible pregnancies are monitored for the level of maternal anti-D. At present, the monitoring of anti-D levels is performed by the indirect antiglobulin test complemented ...

journal_title：Transfusion

authors： Christensson M,Bremme K,Shanwell A,Westgren M,Christensson B

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Almost 20% of parvovirus B19 foetal infections require intrauterine transfusions. In addition, myocardial dysfunction has been observed in severe parvovirus B19 infections. One objective of an intrauterine exchange transfusion (IUET) is to avoid an overload during the transfusion. Our aim was to study the ob...

journal_title：Transfusion

authors： Vanspranghels R,Houfflin-Debarge V,Vaast P,Coulon C,Clouqueur E,Hanssens S,Rakza T,Subtil D,Garabedian C

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Deferral for travel to malaria-endemic areas excludes many blood donors in the United States. Most transfusion-transmitted malaria is associated with lengthy residence in malaria-endemic areas rather than routine travel. This study compares the impact of existing deferral requirements to the risk that a pres...

journal_title：Transfusion

authors： Spencer B,Steele W,Custer B,Kleinman S,Cable R,Wilkinson S,Wright D

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Platelets pose the greatest transfusion-transmitted infectious risk among blood products. Refrigeration of platelets can mitigate bacterial contamination and extend platelet shelf life. Implementation of pathogen reduction technologies (PRTs) at blood banks has become increasingly popular to protect against ...

journal_title：Transfusion

authors： Agey A,Reddoch-Cardenas K,McIntosh C,Sharma U,Cantu C,Cap A,Bynum J

更新日期：2020-12-08 00:00:00

abstract：:Attention to the accurate and precise measurement of the white cell (WBC) content of transfused products has risen in response to awareness of the potential benefits of WBC-depleted components and the development of technical capabilities to produce these components. The techniques thus far reported have focused on th...

journal_title：Transfusion

authors： Dumont LJ

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Prototypes of platelet (PLT) substitutes have been studied and the focus was on a dodecapeptide, HHLGGAKQAGDV (H12), which is a fibrinogen gamma-chain carboxy-terminal sequence (gamma 400-411) and exists only in the fibrinogen domain. STUDY DESIGN AND METHODS:H12 was conjugated to the surface of polymerized...

journal_title：Transfusion

authors： Okamura Y,Takeoka S,Teramura Y,Maruyama H,Tsuchida E,Handa M,Ikeda Y

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The Verax PGD rapid test for bacteria in platelets (PLTs) has been updated to simplify workflow and improve specificity and sensitivity by employing a novel sequential format. The performance of this updated version, called PGDprime, was evaluated to determine its suitability for use as an FDA-cleared "safet...

journal_title：Transfusion

authors： Vallejo RP,Shinefeld L,LaVerda D,Best N,Lawrence G,Lousararian A,Hornbaker N,Rasmusson P,Mintz PD

更新日期：2020-11-01 00:00:00

abstract：:In April 2017, a workshop sponsored by the National Heart, Lung, and Blood Institute, Division of Blood Diseases and Resources, and the Center for Translation Research and Implementation Science was held to discuss blood availability and transfusion safety in low- and middle-income countries (LMICs). The purpose of th...

journal_title：Transfusion

authors： Custer B,Zou S,Glynn SA,Makani J,Tayou Tagny C,El Ekiaby M,Sabino EC,Choudhury N,Teo D,Nelson K,Peprah E,Price L,Engelgau MM

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Chronic transfusion in sickle cell disease (SCD) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. The aim of our study was to assess the safety and efficacy of automated red blood cell exchange (aRBX) in patients with SCD pre...

journal_title：Transfusion

authors： Dedeken L,Lê PQ,Rozen L,El Kenz H,Huybrechts S,Devalck C,Diallo S,Heijmans C,Ferster A

更新日期：2018-06-01 00:00:00