Analysis of apheresis content of progenitor cell collections from normal donors to whom granulocyte-colony-stimulating factor is administered.

abstract：BACKGROUND:Decisions on prophylactic platelet (PLT) transfusions are generally based on the recipient's PLT count, but few clinicians are aware of precision and accuracy of the PLT counting methods used by the clinical laboratory. Each PLT counting technology has its specific inaccuracy, especially in thrombocytopenic ...

journal_title：Transfusion

authors： Hummel K,Sachse M,Hoffmann JJML,van Dun LPJM

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The introduction of prestorage white cell (WBC) reduction in random-donor platelet concentrates in Canada has increased the occurrence of particulate material in PCs. The effects of filtration on platelet activation state and the activation of plasma enzyme systems were assessed. STUDY DESIGN AND METHODS:Pa...

journal_title：Transfusion

authors： Devine DV,Bradley AJ,Maurer E,Levin E,Chahal S,Serrano K,Gyongyossy-Issa MI

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

journal_title：Transfusion

authors： Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units (CBUs) were electively stored in private CB banks. Unlike public banks, which utilize specific criteria...

journal_title：Transfusion

authors： Sun J,Allison J,McLaughlin C,Sledge L,Waters-Pick B,Wease S,Kurtzberg J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:RBC components collected from donors with sickle cell trait frequently occlude WBC-reduction filters. In vitro, sickle trait RBCs have the potential for sickle Hb (Hb S) polymerization at low oxygen saturations and high Hb concentrations. STUDY DESIGN AND METHOD:To determine if the low pH and high osmolarit...

journal_title：Transfusion

authors： Stroncek DF,Rainer T,Sharon V,Byrne KM,Noguchi CT,Klein HG,Schechter AN,Leitman SF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Thrombotic microangiopathies (TMA) are systemic vasoocclusive disorders associated with significant morbidity and mortality. Rapid and reliable diagnosis of TMA is critical. The diagnosis is complicated by a lack of objective and sensitive laboratory testing as well as multiple concurrent diseases, including...

journal_title：Transfusion

authors： Dwyre DM,Bell AM,Siechen K,Sethi S,Raife TJ

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The Lu(b) antigen is expressed on red blood cells (RBCs) of the majority of individuals in all populations. Its absence in transfused patients may lead to alloantibody production and mild-to-moderate transfusion reactions, and in pregnancies to mild hemolytic disease of the fetus and newborn. This report des...

journal_title：Transfusion

authors： Garcia-Sanchez F,Pardi C,Kupatawintu P,Thornton N,Rodriguez MA,Lucea I,Sood C,Ochoa-Garay G

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Hyperhemolysis syndrome (HS) has been well described both in sickle cell disease (SCD) and non-SCD patients. The pathogenesis remains unclear. The possible mechanisms include bystander hemolysis, suppression of erythropoiesis, and destruction of red cells (RBCs) due to contact lysis via activated macrophages...

journal_title：Transfusion

authors： Win N,New H,Lee E,de la Fuente J

更新日期：2008-06-01 00:00:00

abstract：:Erythrocytes stored in the new CPD-adenine anticoagulant (CPDA-1) barely met the 70 per cent 24-hour postinfusion 51Cr recoveries on day 35 when stored at hematocrit greater than or equal to 75 per cent. CPDA-1 differs from CPD in that it has 1.25 times the glucose concentration plus 17.3 mg adenine/63 ml. In an effor...

journal_title：Transfusion

authors： Moore GL,Ledford ME,Peck CC

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is an accepted method to prevent some transfusion-transmitted hepatitis B virus (HBV) infections. However, anti-HBc testing may result in donor loss due to unspecific results in the currently available anti-HBc tests. Alg...

journal_title：Transfusion

authors： Juhl D,Luhm J,Görg S,Ziemann M,Hennig H

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...

journal_title：Transfusion

authors： Ramirez-Arcos S,Evans S,McIntyre T,Pang C,Yi QL,DiFranco C,Goldman M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:In cases of warm autoimmune hemolytic anemia (WAIHA), crossmatch incompatible RBCs are most often used for transfusion. The determination of the in vivo survival of transfused and autologous RBCs in WAIHA is helpful in the assessment of the efficacy of transfusion and other therapeutic interventions. CASE R...

journal_title：Transfusion

authors： Zeiler T,Müller JT,Hasse C,Kullmer J,Kretschmer V

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The HCV lookback program was designed to trace and offer testing to recipients who received transfusion of blood components from donors subsequently found to be anti-HCV positive. Only approximately 20 percent of transfusable components entering lookback did result in a recipient obtaining testing through th...

journal_title：Transfusion

authors：

更新日期：2002-09-01 00:00:00

abstract：:A unit-dose system was designed to dispense precise quantities of blood in a form ready for immediate transfusion into neonatal patients. The principles were similar to those used by pharmacies to dispense individual doses of drugs. In the blood center, the precise volume of blood ordered for a neonatal patient was as...

journal_title：Transfusion

authors： Strauss RG,Crawford GF,Elbert C,Floss AM,Liesch M

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:To avoid the need, in serial apheresis donors, either to delay plateletpheresis until a predonation platelet count is completed or to obtain a postdonation count after each procedure, a statistical model has been developed to predict the postdonation platelet count from the donor predonation platelet count, ...

journal_title：Transfusion

authors： Cabezudo I,Winegarden DK,Randels MJ,Strauss RG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Since screening for antibody to hepatitis C virus (HCV) was introduced in 1990, posttransfusion hepatitis has been reduced to nearly background levels. This has led to reconsideration of the value of testing donated blood for elevated alanine aminotransferase (ALT). The contribution of ALT testing in detecti...

journal_title：Transfusion

authors： Sankary TM,Yang G,Romeo JM,Ulrich PP,Busch MP,Rawal BD,Vyas GN

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery ...

journal_title：Transfusion

authors： Balint B,Paunovic D,Vucetic D,Vojvodic D,Petakov M,Trkuljic M,Stojanovic N

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Erythrocytapheresis (ECP), automated red blood cell exchange, is increasingly being used for chronic transfusion therapy in sickle cell disease (SCD) as it is an isovolumetric transfusion, is more effective in lowering hemoglobin (Hb)S, and can limit iron overload. Because ECP requires increased blood exposu...

journal_title：Transfusion

authors： Wahl SK,Garcia A,Hagar W,Gildengorin G,Quirolo K,Vichinsky E

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

journal_title：Transfusion

authors： Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Although infrequent, episodes of transfusion-associated bacterial sepsis may lead to serious outcomes or death and therefore are of concern. This study evaluates the sensitivity of three surrogate tests for the presence of bacteria in platelet concentrates: cessation of swirling, low extracellular pH, and lo...

journal_title：Transfusion

authors： Wagner SJ,Robinette D

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:In 1996, the Danish National Board of Health recommended hepatitis C virus (HCV) lookback to identify recipients of blood components from donors found to be positive since the implementation of anti-HCV screening in 1991. STUDY DESIGN AND METHODS:The aim was to accumulate results of the lookback at a nation...

journal_title：Transfusion

authors： Christensen PB,Groenbaek K,Krarup HB

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Passenger lymphocyte-mediated graft-versus-host disease (GVHD) in solid organ transplantation (SOT-GVHD) is considered a rare complication, particularly among recipients of lung allografts. The risk of transfusion-associated GVHD (TA-GVHD) in solid organ transplants is also considered rare. The suspicion of ...

journal_title：Transfusion

authors： Pavenski K,Kamel-Reid S,Wei C,Cserti-Gazdewich CM

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:This study evaluated the effect of routine, uncontrolled, Israeli field storage conditions on the stability and efficacy of Lyo-Plas N freeze-dried plasma (FDP). We evaluated clotting factors V, VIII, and XI; proteins S and C; fibrinogen; partial thromboplastin time (PTT); antithrombin III (ATIII); von Wille...

journal_title：Transfusion

authors： Zur M,Glassberg E,Gorenbein P,Epstein E,Eisenkraft A,Misgav M,Avramovich E

更新日期：2019-11-01 00:00:00

abstract：:The ability of the monocyte monolayer assay (MMA) and the chemiluminescence test (CLT) to predict the clinical significance of alloantibodies associated with hemolytic disease of the newborn (HDN) was assessed by the use of 22 well-characterized antisera--predominantly anti-D--from alloimmunized pregnant women. Sevent...

journal_title：Transfusion

authors： Lucas GF,Hadley AG,Nance SJ,Garratty G

更新日期：1993-06-01 00:00:00

abstract：:A technique of platelet concentrate preparation and storage is presented which permits the maximum number of viable and functional platelets to be preserved for periods of 72 hours. Although the storage conditions must be followed precisely, the method is nevertheless simple to perform and does not require specialized...

journal_title：Transfusion

authors： Slichter SJ,Harker LA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Monitoring blood transfusion for overutilization is standard practice at most institutions. STUDY DESIGN AND METHODS:This study monitored for underutilization of blood transfusion over a 14-month period, by evaluating patients who had Hb levels that were reported to be <5 g per dL or platelet counts <10 x 1...

journal_title：Transfusion

authors： Saxena S,Wehrli G,Makarewicz K,Sartorelli J,Shulman IA

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Although the risk of transmitting infectious agents by blood transfusion is dramatically reduced after donor selection, leukoreduction, and laboratory testing, some could still be present in donor's blood. A description of metagenomes in blood products eligible for transfusion represents relevant information...

journal_title：Transfusion

authors： Lau P,Cordey S,Brito F,Tirefort D,Petty TJ,Turin L,Guichebaron A,Docquier M,Zdobnov EM,Waldvogel-Abramowski S,Lecompte T,Kaiser L,Preynat-Seauve O

更新日期：2017-07-01 00:00:00