A chloroquine elution technique for platelet serology.

abstract：BACKGROUND:Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical treatment (PCT) process with amotosalen-HCl and long-wavelength ultraviolet light (UVA), which cross-links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentra...

journal_title：Transfusion

authors： Lin L,Hanson CV,Alter HJ,Jauvin V,Bernard KA,Murthy KK,Metzel P,Corash L

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The use of hematopoietic progenitor cell (HPC) transplantation has rapidly expanded in recent years. Currently, several sources of HPCs are available for transplantation including peripheral blood HPCs (PBPCs), cord blood cells, and marrow cells. Of these, PBPC collection has become the major source of HPCs....

journal_title：Transfusion

authors： Chen J,Burns KM,Babic A,Carrum G,Kennedy M,Segura FJ,Garcia S,Potts S,Leveque C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...

journal_title：Transfusion

authors： D'Alessandro A,Thomas KA,Stefanoni D,Gamboni F,Shea SM,Reisz JA,Spinella PC

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

journal_title：Transfusion

authors： Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Cell-free fetal DNA in maternal plasma opens the way for routine risk-free diagnosis of fetal D status of D- mothers. The focus was on accuracy of RHD typing and confirmation of fetal DNA in maternal plasma while RHD was not detected. STUDY DESIGN AND METHODS:Plasma DNA was extracted (by manual and/or autom...

journal_title：Transfusion

authors： Brojer E,Zupanska B,Guz K,Orziñska A,Kaliñska A

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The high-prevalence antigen Jr(a) is carried on the ATP-binding cassette transporter ABCG2. The ABCG2 gene consists of 16 exons and its translation start codon is located on the second exon. Although the occurrence of the Jr(a-) phenotype is rare, several ABCG2 null alleles have been reported. We report a ne...

journal_title：Transfusion

authors： Ogasawara K,Osabe T,Suzuki Y,Tsuneyama H,Isa K,Kawai M,Obara K,Ogiyama Y,Ito S,Uchikawa M,Satake M,Tadokoro K

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The relationship between length of storage of red blood cell (RBC) units and biochemical changes has been well studied, but little is known about the progression of cellular immunomodulative properties in blood recipients. This study aims to quantify in vitro T-cell activation and cytokine release by white b...

journal_title：Transfusion

authors： Karam O,Tucci M,Toledano BJ,Robitaille N,Cousineau J,Thibault L,Lacroix J,Le Deist F

更新日期：2009-11-01 00:00:00

abstract：:Seven hundred and sixty-three blood donors previously typed for HLA-A and B antigens were asked to consider donating bone marrow to unrelated patients for whom no HLA-matched sibling was available. Eighty-eight percent (668) indicated willingness to donate marrow, and of these, 615 (81%) participated in testing and 53...

journal_title：Transfusion

authors： McElligott MC,Menitove JE,Aster RH

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Severe transfusion-related acute lung injury is often caused by antibodies directed against the human neutrophil alloantigen (HNA)-3a. HNA-3a results from an amino acid exchange (Arg154Gln) in the first extracellular loop of the choline transporter-like protein 2 (CTL2). The characteristics of the binding do...

journal_title：Transfusion

authors： Berthold T,Wesche J,Kuhnert K,Fürll B,Hippe H,Hoppen J,Reil A,Muschter S,Bux J,Greinacher A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:In August 2016, the Food and Drug Administration advised US blood centers to screen all whole blood and apheresis donations for Zika virus (ZIKV) with an individual-donor nucleic acid test (ID-NAT) or to use approved pathogen reduction technology (PRT). The cost of implementing this guidance nationally has n...

journal_title：Transfusion

authors： Ellingson KD,Sapiano MRP,Haass KA,Savinkina AA,Baker ML,Henry RA,Berger JJ,Kuehnert MJ,Basavaraju SV

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:In 2014, we experienced the first isolation of Lactococcus garvieae from a platelet concentrate (PC). Thereafter, L. garvieae contamination of PCs occurred in two more cases in Japan. It is rare that bacterial contamination with uncommon strains like this species occurs frequently within a short period. Ther...

journal_title：Transfusion

authors： Kozakai M,Matsumoto C,Matsumoto M,Takakura A,Matsubayashi K,Satake M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Peripheral blood white cells (leukocytes) (PBLs) have been used as effective targets for genetic manipulation by transduction with retroviruses in open systems. A semi-closed hollow-fiber bioreactor was tested for culturing and transducing lymphocytes. STUDY DESIGN AND METHODS:PBLs were isolated from five h...

journal_title：Transfusion

authors： Shankar R,Whitley CB,Pan D,Burger S,McCullough J,Stroncek D

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Supply of cytomegalovirus (CMV)-seronegative blood products in Australia is an ongoing challenge. Requests for CMV-negative products are increasing with prediction that the demand will exceed supply by 2019. Clinical information evaluating how these products are being utilized by health providers within Aust...

journal_title：Transfusion

authors： Hirani R,Tohidi-Esfahani I,Mondy P,Irving DO

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:On rare occasions, upon thawing of stored cryoprecipitate components, clots are observed on visual inspection. Although it has been assumed that the clot reflects fibrinogen to fibrin conversion, there are few published studies that document that this assumption is correct. Our studies were conducted to furt...

journal_title：Transfusion

authors： MacPhee M,Wilmer B,Beall D,Moroff G

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Transfusion of platelet concentrates (PCs) is the basic treatment for severe platelet disorders. PCs carry the risk of pathogen transmission, especially bacteria. Pathogen reduction (PR) by addition of photochemical reagents and irradiation with visible or ultraviolet (UV) light can significantly reduce this...

journal_title：Transfusion

authors： Mohr H,Steil L,Gravemann U,Thiele T,Hammer E,Greinacher A,Müller TH,Völker U

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Retrospective studies suggested that storage age of RBCs is associated with inflammation and thromboembolism. The Red Cell Storage Duration Study (RECESS) trial randomized subjects undergoing complex cardiac surgery to receive RBCs stored for shorter versus longer periods, and no difference was seen in the p...

journal_title：Transfusion

authors： Spinella PC,Sniecinski RM,Trachtenberg F,Inglis HC,Ranganathan G,Heitman JW,Szlam F,Danesh A,Stone M,Keating SM,Levy JH,Assmann SF,Steiner ME,Doctor A,Norris PJ

更新日期：2019-04-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:The FDA requirement for sensitivity of viral NAT methods used in blood screening is a 95-percent detection limit of 100 copies per mL, whereas the NAT screening system should have a sensitivity of at least 5000 copies per mL per individual donation. According to the Common Technical Specifications of the Eur...

journal_title：Transfusion

authors： Lelie PN,van Drimmelen HA,Cuypers HT,Best SJ,Stramer SL,Hyland C,Allain JP,Moncharmont P,Defer C,Nübling M,Glauser A,da Silva Cardoso M,Viret JF,Lankinen MH,Grillner L,Wirthmüller U,Coste J,Schottstedt V,Masecar B,D

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Liberal transfusion strategy increases the risk of acute lung injury (ALI), but specific transfusion-related factors have not been characterized. We tested the hypotheses that storage age and specific type of blood products are associated with increased risk of ALI in mechanically ventilated patients. STUDY...

journal_title：Transfusion

authors： Gajic O,Rana R,Mendez JL,Rickman OB,Lymp JF,Hubmayr RD,Moore SB

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The recent H1N1 pandemic provided an opportunity to conceptually assess the possibility of rapidly providing a "hyperimmune" human immunoglobulin (H-IVIG) to an emerging infectious disease, in useful quantities with respect to public health. Commercial-scale H-IVIG production from plasma collected from donor...

journal_title：Transfusion

authors： Kreil TR,Mc Vey JK,Lei LS,Camacho L,Wodal W,Kerschbaum A,Segura E,Vandamme E,Gavit P,Ehrlich HJ,Barrett PN,Baker DA

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:A storage period of 42 days has been approved by the FDA for RBCs stored in NUTRICEL (AS-3). This study was undertaken to provide data to the FDA about the feasibility of salvaging AS-3 RBCs at the end of their storage period by rejuvenation and freezing, and to evaluate the effect of rejuvenation on indicat...

journal_title：Transfusion

authors： Lockwood WB,Hudgens RW,Szymanski IO,Teno RA,Gray AD

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Guidelines for red blood cell (RBC) transfusions exist; however, transfusion practices vary among centers. This study aimed to analyze transfusion practices and the impact of patients and institutional characteristics on the indications of RBC transfusions in preterm infants. STUDY DESIGN AND METHODS:RBC tr...

journal_title：Transfusion

authors： dos Santos AM,Guinsburg R,Procianoy RS,Sadeck Ldos S,Netto AA,Rugolo LM,Luz JH,Bomfim O,Martinez FE,de Almeida MF,Brazilian Network on Neonatal Research.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The Japanese Red Cross (JRC) implemented a fully automated pooling and nucleic acid amplification test (NAT) system for testing seronegative donations. The JRC sample repository and repeat blood donations allowed for lookback and follow-up studies of hepatitis B virus (HBV) DNA-positive donors, who tested ne...

journal_title：Transfusion

authors： Yoshikawa A,Gotanda Y,Minegishi K,Taira R,Hino S,Tadokoro K,Ohnuma H,Miyakawa K,Tachibana K,Mizoguchi H,Japanese Red Cross NAT Screening Research Group.

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Due to physiological demands, children and premenopausal women are at risk of developing iron deficiency. In premenopausal women, the risk may be further increased by repeated whole blood donations. Short-term consequences of iron deficiency in infancy include impaired cognitive development and lower IQ scor...

journal_title：Transfusion

authors： Rigas AS,Pedersen OB,Rostgaard K,Sørensen E,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:A novel WBC-reduction in-line whole-blood (WB) filter that does not retain platelets was evaluated to assess the filtration performance and, after processing WB by the platelet-rich plasma (PRP) method, to analyze the storage quality of filtered platelet concentrate (PC) units. STUDY DESIGN AND METHODS:To a...

journal_title：Transfusion

authors： Lozano ML,Pérez-Ceballos E,Rivera J,Paunovic D,Candela MJ,Vicente V

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Hemolytic disease of the fetus and newborn (HDFN) is a severe disease, resulting from maternal red cell (RBC) alloantibodies directed against fetal RBCs. The effect of a first-trimester antibody screening program on the timely detection of HDFN caused by antibodies other than anti-D was evaluated. STUDY DES...

journal_title：Transfusion

authors： Koelewijn JM,Vrijkotte TG,van der Schoot CE,Bonsel GJ,de Haas M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Transfusion support of S-s- patients is very challenging but can now be alleviated by genotyping mutations in the GYPB gene to predict their U- or U+(var) phenotype. However, the phenotype predicted by genotyping does not always correspond to the observed phenotype of red blood cells (RBCs), which requires f...

journal_title：Transfusion

authors： Willemetz A,Nataf J,Peyrard T,Arnaud L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Storage of blood units (for 35-42 days, depending on the preservative solution) has been reported to induce changes (e.g., reduction of sialic acid level) in red cells that are expected to alter their aggregability. STUDY DESIGN AND METHODS:The aggregability of stored red cells was monitored in their autolo...

journal_title：Transfusion

authors： Hovav T,Yedgar S,Manny N,Barshtein G

更新日期：1999-03-01 00:00:00