Alteration of red cell aggregability and shape during blood storage.

abstract：BACKGROUND:Transfusion safety rests heavily on the health of blood donors. Although they are perceived as being healthier than average, little is known about their long-term disease patterns and to which extent the blood banks' continuous efforts to optimize donor selection has resulted in improvements. Mortality and c...

journal_title：Transfusion

authors： Edgren G,Tran TN,Hjalgrim H,Rostgaard K,Shanwell A,Titlestad K,Wikman A,Norda R,Jersild C,Wideroff L,Gridley G,Adami J,Melbye M,Nyrén O,Reilly M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Platelets contain several mediators, belonging to a family of proinflammatory cytokines named chemokines, that are stored in the organelles. Release and accumulation of these chemokines during storage of platelet concentrates (PCs) might be responsible for nonhemolytic transfusion reactions. STUDY DESIGN AN...

journal_title：Transfusion

authors： Bubel S,Wilhelm D,Entelmann M,Kirchner H,Klüter H

更新日期：1996-05-01 00:00:00

abstract：:Severe acute hemolytic anemia developed in a woman following treatment with multiple antibiotics for possible postpartum uterine infection. On admission, the hemoglobin was 5 g per dL (50 g/L), the reticulocytes were 35 percent (0.350), the direct antiglobulin test was strongly positive for IgG and C3d (mixed fields),...

journal_title：Transfusion

authors： Gallagher NI,Schergen AK,Sokol-Anderson ML,Sheahan EJ,Chaplin H

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to estimate the risk of human immunodeficiency virus (HIV) infection via the transfusion of blood tested by inappropriately stored or expired rapid antibody assays in Zambia. STUDY DESIGN AND METHODS:Surgical patients (n = 370) were tested with antibody assays (HIV-spot and HIV...

journal_title：Transfusion

authors： Consten EC,van der Meer JT,de Wolf F,Heij HA,Henny PC,van Lanschot JJ

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Routine HCV NAT of blood donors to detect persons in the preseroconversion phase of acute infection was introduced in Canada in October 1999. The source of virus exposure was investigated in the first, and to date only, blood donor found to be HCV NAT positive, anti-HCV negative in Canada. He was a regular d...

journal_title：Transfusion

authors： Larke B,Hu YW,Krajden M,Scalia V,Byrne SK,Boychuk LR,Klein J

更新日期：2002-06-01 00:00:00

abstract：:Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...

journal_title：Transfusion

authors： Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JS

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

journal_title：Transfusion

authors： Valeri CR,Lane JP,Srey R,Ragno G

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Dengue virus transmission by blood transfusion is a rarely reported event. CASE REPORT:During a dengue outbreak in São Paulo city, a regular plateletpheresis donor informed the blood bank of being diagnosed a few days after donation. The recipient was hospitalized and displayed symptoms and laboratory evide...

journal_title：Transfusion

authors： Levi JE,Nishiya A,Félix AC,Salles NA,Sampaio LR,Hangai F,Sabino EC,Mendrone A Jr

更新日期：2015-05-01 00:00:00

abstract：:The growth of two strains of Serratia marcescens in blood components was tested in this study. One of the strains had been implicated in the epidemic of transfusion-associated sepsis experienced in Denmark and Sweden in 1991. In whole blood with a final concentration of 100 colony-forming units per mL of S. marcescens...

journal_title：Transfusion

authors： Gong J,Högman CF,Hambraeus A,Johansson CS,Eriksson L

更新日期：1993-10-01 00:00:00

abstract：:Microaggregates in various blood preparations were studied, before and after filtration, using an optical scattering (laser) technique which measures number density and size of aggregates in flowing blood. These measurements were comparable to screen filtration pressures. In all blood units, storage increased aggregat...

journal_title：Transfusion

authors： Reynolds LO,Simon TL

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Hypericin is a potent virucidal agent with activity against a broad range of enveloped viruses and retroviruses. The effective virucidal activity emanates from a combination of photodynamic and lipophilic properties. Hypericin binds cell membranes (and, by inference, virus membranes) and crosslinks virus cap...

journal_title：Transfusion

authors： Lavie G,Mazur Y,Lavie D,Prince AM,Pascual D,Liebes L,Levin B,Meruelo D

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

journal_title：Transfusion

authors： Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

更新日期：2004-08-01 00:00:00

abstract：:An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

journal_title：Transfusion

authors： Halima D,Garratty G,Bueno R

更新日期：1982-11-01 00:00:00

abstract：:Blood centrifugation, with a continuous-flow or semicontinuous-flow system, was used in the treatment of 17 patients with various hematologic disorders. Total plasma exchange (TPE) controlled symptoms of hyperviscosity and arrested bleeding in three patients. In two patients, TPE made is possible to perform urgent sur...

journal_title：Transfusion

authors： Pineda AA,Brzica SM Jr,Taswell HF

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The factors contributing to RBC agglutination are complex. The RBC cytoskeleton's participation in and contribution to this phenomenon are difficult to separate from those of the plasma membrane. Immunoreactive, cytoskeleton-free, band 3-enriched microvesicles can be generated from normal RBCs. Band 3 has be...

journal_title：Transfusion

authors： Jaime JC

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Transfusion-related characteristics have been hypothesized to cause allergic transfusion reactions (ATRs) but they have not been thoroughly studied. The primary objective of this study is to evaluate the associations of infusion rate, infusion volume, ABO mismatching, component age, and pretransfusion medica...

journal_title：Transfusion

authors： Savage WJ,Tobian AA,Savage JH,Hamilton RG,Borge PD,Kaufman RM,Ness PM

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Demonstration of viable Chlamydia (Chlamydophila) pneumoniae in peripheral blood mononuclear cells (PBMNCs) is essential to understand the involvement of C. pneumoniae in atherosclerosis. Nevertheless, the prevalence of viable C. pneumoniae in the blood of healthy donors has not yet been studied. STUDY DESI...

journal_title：Transfusion

authors： Yamaguchi H,Yamada M,Uruma T,Kanamori M,Goto H,Yamamoto Y,Kamiya S

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Quantification of CD34+ stem and progenitor cells is predominantly performed by flow cytometric analysis of cells prepared by whole blood staining and red cell lysis. This method also includes cell washing, which is thought to cause the destruction and loss of some of the nucleated cells (NCs). To address th...

journal_title：Transfusion

authors： Fritsch G,Printz D,Stimpfl M,Dworzak MN,Witt V,Pötschger U,Buchinger P

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Some jurisdictions require leukoreduction of cellular blood components. The only whole blood collection set with a platelet-saving filter uses citrate-phosphate-dextrose (CPD) as storage solution. Substituting CPD with citrate-phosphate-dextrose-adenine (CPDA-1) increases shelf life from 21 to 35 days. This ...

journal_title：Transfusion

authors： Sivertsen J,Braathen H,Lunde THF,Kristoffersen EK,Hervig T,Strandenes G,Apelseth TO

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Techniques for banking cord blood units (CBUs) as source for hematopoietic stem cell transplantation have been developed over the past 20 years, aimed to improve laboratory efficiency without altering the biologic properties of the graft. A large-scale, registry-based assessment of the impact of the banking ...

journal_title：Transfusion

authors： Saccardi R,Tucunduva L,Ruggeri A,Ionescu I,Koegler G,Querol S,Grazzini G,Lecchi L,Nanni Costa A,Navarrete C,Pouthiers F,Larghero J,Regan D,Freeman T,Bittencourt H,Kenzey C,Labopin M,Baudoux E,Rocha V,Gluckman E

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00

abstract：:The hemostat, sealant, and adhesive components of the surgical toolbox continue to evolve and enter clinical practice at a rapid rate. The goal of this comprehensive, sequential review is to update these components to include those now available (February 2012) as well as to explore cost and regulatory factors that im...

journal_title：Transfusion

authors： Spotnitz WD,Burks S

更新日期：2012-10-01 00:00:00

abstract：:Sixty English-language articles on the motivation and recruitment of blood donors and nondonors are reviewed and evaluated. Apparently researchers have been finding essentially the same results for approximately twenty years. Motivations to donate are: altruism/humanitarian, personal or family credit, social pressure,...

journal_title：Transfusion

authors： Oswalt RM

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Variant RHCE alleles with diminished expression of C, c, E, and e antigens have been described and indicate the genetic diversity of this gene locus in several populations. In this study the molecular background of variant RhCE antigens identified by standard serologic routine testing in German blood donors ...

journal_title：Transfusion

authors： Bugert P,Scharberg EA,Geisen C,von Zabern I,Flegel WA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Recently, a quasi-lipid-enveloped (LE) form of the traditionally nonlipid-enveloped (NLE) hepatitis A virus (HAV) was described in human serum and cell culture-derived HAV stocks. This discovery challenges the understanding of HAV reduction in virus clearance studies of plasma products, which were performed ...

journal_title：Transfusion

authors： Kapsch AM,Farcet MR,Antoine G,Kreil TR

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Data on red blood cell (RBC) transfusion in the United States show variation in practice and overprescribing or overdosing is considered to be prevalent. Education or restrictive interventions could modify practice. STUDY DESIGN AND METHODS:RBC transfusion and mortality rates were recorded in a single insti...

journal_title：Transfusion

authors： Tavares MM,Diquattro PJ,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Using the 5'-rapid amplification of cDNA ends technique with the ex vivo culture of AC133-CD34+ cells, a transcription start site was recently identified approximately 0.7 kb upstream from the transcription start sites previously determined. The transcripts from the alternative starting exon 1a were demonstr...

journal_title：Transfusion

authors： Hata Y,Kominato Y,Takizawa H,Tabata S,Michino J,Nishino K,Yasumura S,Yamamoto F

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Acute trauma coagulopathy (ATC) after military trauma has not been comprehensively studied. ATC is defined as a prolonged prothrombin time ratio (PTr) or reduced clot amplitude (A5) in viscoelastic testing. Compared to civilian trauma, military trauma has more injuries from explosions and gunshot wounds (GSW...

journal_title：Transfusion

authors： Woolley T,Gwyther R,Parmar K,Kirkman E,Watts S,Midwinter M,Lucca JD,Hunt BJ

更新日期：2020-06-01 00:00:00