Abstract:
BACKGROUND:Guidelines for red blood cell (RBC) transfusions exist; however, transfusion practices vary among centers. This study aimed to analyze transfusion practices and the impact of patients and institutional characteristics on the indications of RBC transfusions in preterm infants. STUDY DESIGN AND METHODS:RBC transfusion practices were investigated in a multicenter prospective cohort of preterm infants with a birth weight of less than 1500 g born at eight public university neonatal intensive care units of the Brazilian Network on Neonatal Research. Variables associated with any RBC transfusions were analyzed by logistic regression analysis. RESULTS:Of 952 very-low-birth-weight infants, 532 (55.9%) received at least one RBC transfusion. The percentages of transfused neonates were 48.9, 54.5, 56.0, 61.2, 56.3, 47.8, 75.4, and 44.7%, respectively, for Centers 1 through 8. The number of transfusions during the first 28 days of life was higher in Center 4 and 7 than in other centers. After 28 days, the number of transfusions decreased, except for Center 7. Multivariate logistic regression analysis showed higher likelihood of transfusion in infants with late onset sepsis (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.8-4.4), intraventricular hemorrhage (OR, 9.4; 95% CI, 3.3-26.8), intubation at birth (OR, 1.7; 95% CI, 1.0-2.8), need for umbilical catheter (OR, 2.4; 95% CI, 1.3-4.4), days on mechanical ventilation (OR, 1.1; 95% CI, 1.0-1.2), oxygen therapy (OR, 1.1; 95% CI, 1.0-1.1), parenteral nutrition (OR, 1.1; 95% CI, 1.0-1.1), and birth center (p < 0.001). CONCLUSIONS:The need of RBC transfusions in very-low-birth-weight preterm infants was associated with clinical conditions and birth center. The distribution of the number of transfusions during hospital stay may be used as a measure of neonatal care quality.
journal_name
Transfusionjournal_title
Transfusionauthors
dos Santos AM,Guinsburg R,Procianoy RS,Sadeck Ldos S,Netto AA,Rugolo LM,Luz JH,Bomfim O,Martinez FE,de Almeida MF,Brazilian Network on Neonatal Research.doi
10.1111/j.1537-2995.2009.02373.xsubject
Has Abstractpub_date
2010-01-01 00:00:00pages
150-9issue
1eissn
0041-1132issn
1537-2995pii
TRF2373journal_volume
50pub_type
杂志文章,多中心研究相关文献
TRANSFUSION文献大全abstract:BACKGROUND:Little information is available regarding blood supply safety in Afghanistan. The purpose of this study was to assess blood safety through serologic and observational measures in Afghanistan. STUDY DESIGN AND METHODS:This cross-sectional assessment included the 40 highest-volume facilities collecting and tr...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.12005
更新日期:2013-09-01 00:00:00
abstract::The Platelet Monitoring System (PMS) and the Non-invasive Assessment of Platelet Shape and Concentration (NAPSAC) instruments which relate light scattering characteristics of platelet concentrates (PC) to platelet concentration and shape, were evaluated to determine their accuracy in assessing platelet quality during ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1989.29389162737.x
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:According to Landsteiner's law, alloantibodies are prevalent and autoantibodies are absent in the ABO blood group system. However, one study (Spalter et al., Blood 1999;93:4418-24) has suggested that low-affinity ABO autoantibodies, mitigated by anti-idiotypic immunoglobulins are also prevalent, while anothe...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2011.03381.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:In 1999, NAT of blood donations was implemented to detect "window-period" infections. Blood donors who have confirmed NAT results positive for the presence of HCV in the absence of anti-HCV are likely to have been recently infected. Of over 26.8 million donations tested between March 3, 1999, and March 31, 2...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2004.00623.x
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:To minimize the bacterial contamination rate in blood collected from donors, a study was designed to evaluate the suitability of a single-use chlorhexidine-alcohol antiseptic for donor arm preparation at all blood collection venues in Australia. STUDY DESIGN AND METHODS:A prospective study of bacterial load...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2004.03362.x
更新日期:2004-08-01 00:00:00
abstract::Flow cytometric analysis was performed on red cells (RBCs) to compare the antigen activity of various Rh phenotypes, including the rare variants Del and Du (both high-grade and low-grade), whose genotypes were confirmed or presumed by the family study. This appears to be the first report that the Del phenotype is due ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1990.30390194344.x
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:It is not known whether increasing the dose of filgrastim after mobilizing chemotherapy improves collection of peripheral blood progenitor cells (PBPC) and leads to faster hematopoietic engraftment after autologous transplantation. STUDY DESIGN AND METHODS:A randomized, open-label, multicenter trial was car...
journal_title:Transfusion
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1537-2995.2003.00273.x
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Because single-donor plateletpheresis concentrates now account for a large percentage of PLT concentrates, the PLT quality of individual donations is increasingly important. There has been little previous work on PLT function in blood donors. STUDY DESIGN AND METHODS:The aim of this study was to investigate...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2004.00368.x
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Plasma thawed and stored at 1 to 6° C for up to 5 days (thawed plasma [TP]) provides rapid availability in emergencies and reduces plasma waste, but it carries risks of coagulation factor loss or activation, bacterial outgrowth, and viral contamination. We characterized changes in amotosalen/ultraviolet A (U...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13973
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Transfusion support of S-s- patients is very challenging but can now be alleviated by genotyping mutations in the GYPB gene to predict their U- or U+(var) phenotype. However, the phenotype predicted by genotyping does not always correspond to the observed phenotype of red blood cells (RBCs), which requires f...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13216
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Storage of pooled platelet concentrates (PCs) with yields above 3.0 x 10(11) platelets per unit in a 1-L PL-732 polyolefin container for 5 days often results in a drop in pH to below 6.0. Recently, new oxygen-permeable platelet containers (1-L PL-2410, 1-L and 1.5-L Compoflex) have been developed. The maxima...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1997.37597293876.x
更新日期:1997-05-01 00:00:00
abstract::Transfusion medicine (TM) physicians provide medical services that benefit all patients such as providing 24-hour laboratory coverage, advising health care providers on test interpretation and selection, validating new methods, and supervising technical personnel. These services ensure delivery of accurate, reliable, ...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.14264
更新日期:2017-10-01 00:00:00
abstract::In therapeutic plasmapheresis, patient plasma is withdrawn and a colloid replacement solution is infused in its place. A 4% to 5% human serum albumin solution in saline is the preferred replacement solution in most instances, even though this practice causes transient mild deficiencies of most plasma proteins. Albumin...
journal_title:Transfusion
pub_type: 杂志文章,评审
doi:10.1111/j.1537-2995.2012.03623.x
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13792
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Blood components are often given prophylactically before the placement of invasive lines in patients with coagulation defects. Little, however, is known about the epidemiology of defects in these patients. The purpose of this study is to ascertain what proportion of intensive care patients who receive invasi...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1996.36996420763.x
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Donor stimulation with granulocyte-colony-stimulating factor (G-CSF) has increased the number of neutrophils (PMNs) that can be collected for granulocyte transfusion therapy. Clinical utility, however, has been limited by the inability to store functional PMNs ex vivo. This study was conducted to determine w...
journal_title:Transfusion
pub_type: 临床试验,杂志文章
doi:10.1111/j.1537-2995.2005.00636.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Current transfusion-related acute lung injury reduction strategies include avoiding transfusion of plasma products collected from female donors or female donors that have been pregnant to reduce transfusion of plasma-containing HLA antibodies. Such a policy considerably decreases the number of donors availab...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/j.1537-2995.2009.02198.x
更新日期:2009-08-01 00:00:00
abstract::An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was dest...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1990.30390194349.x
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:During storage, the activity of the red blood cell (RBC) antioxidant system decreases. Glucose-6-phosphate dehydrogenase (G6PD) is essential for protection against oxidative stress by producing NADPH. G6PD function of RBC transfusion products is reported to remain stable during storage, but activity was meas...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13378
更新日期:2016-02-01 00:00:00
abstract::A technique of platelet concentrate preparation and storage is presented which permits the maximum number of viable and functional platelets to be preserved for periods of 72 hours. Although the storage conditions must be followed precisely, the method is nevertheless simple to perform and does not require specialized...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1976.16176130842.x
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...
journal_title:Transfusion
pub_type: 杂志文章,评审
doi:10.1111/j.1537-2995.2007.01486.x
更新日期:2008-01-01 00:00:00
abstract::The use of citrate-phosphate-dextrose-adenine as an anticoagulant for whole blood increases the storage period permitted for whole blood and red cells from 21 to 35 days. A simulation model was used to analyze the possible consequences for outdates and shortages of the addition of adenine. The model accepts as input (...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1983.23183147306.x
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...
journal_title:Transfusion
pub_type: 临床试验,杂志文章
doi:10.1111/trf.13646
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:ABO is a blood group system of high clinical significance due to the prevalence of ABO variation that can cause major, potentially life-threatening, transfusion reactions. STUDY DESIGN AND METHODS:Using multiple large-scale next-generation sequence data sets, we demonstrate the application of read-depth app...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.13797
更新日期:2016-11-01 00:00:00
abstract::Data collected from 50 saline washed units of red blood cells shows that units washed with one liter of 0.9 per cent NaCl on an IBM cell processor have an average hematocrit of 72.2 per cent, with 84.7 per cent of the white blood cells removed, and only 0.6 per cent of the original total protein remaining. The red blo...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1976.16577039304.x
更新日期:1976-09-01 00:00:00
abstract:BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.2003.00399.x
更新日期:2003-06-01 00:00:00
abstract::A microplate system for performing ABO and Rh(D) blood group determinations with a Kemble Kemtek 1000SP liquid handling processor, an Anthos 2001 microplate reader, an IBM Personal System 2 microcomputer, and Sanguin Forma software is described. The performance of this Kemble/Anthos/IBM/Sanguin microplate system for A...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1993.33593255597.x
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Plasma is commonly used for vitamin K antagonist (VKA) reversal, but observational studies suggest that it is associated with transfusion-related adverse reactions (e.g., volume overload). However, this issue has not previously been addressed in a randomized controlled trial (RCT). STUDY DESIGN AND METHODS:...
journal_title:Transfusion
pub_type: 杂志文章,随机对照试验
doi:10.1111/trf.13191
更新日期:2015-11-01 00:00:00
abstract::Critically ill neonatal infants receive frequent small-volume red cell (RBC) transfusions for replacement of blood drawn for laboratory analysis or for treatment of symptomatic anemia secondary to underlying medical conditions and/or a relative bleeding diathesis. Retrospective review of transfusion practice in a hosp...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1046/j.1537-2995.1993.33593255596.x
更新日期:1993-05-01 00:00:00
abstract:INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...
journal_title:Transfusion
pub_type: 杂志文章
doi:10.1111/trf.15652
更新日期:2020-06-01 00:00:00