The impact of adenine and inventory utilization decisions on blood inventory management.

abstract：BACKGROUND:The residual blood left in the placenta, previously considered a biologic waste, contains sufficient hematopoietic stem and progenitor cells to consistently engraft at least a small recipient. Over the past several years, more than 500 HLA-matched, related and unrelated, allogeneic cord blood transplants hav...

journal_title：Transfusion

authors： Reems JA,Fujita D,Tyler T,Moldwin R,Smith SD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Drug-induced immune pancytopenia is considered an uncommon disorder. CASE REPORT:A 76-year-old woman with metastatic gastric adenocarcinoma received 15 cycles of FOLFOX-6 (oxaliplatin/folinic acid/fluorouracil) with a complete response. Upon disease progression, she was restarted on FOLFOX; during the seven...

journal_title：Transfusion

authors： Fontão-Wendel R,Hoff PM,Lazar A,Freitas D,Novis Y,Patah P,Tsujita M,Balthazar A,Pierroti M,Wendel S

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：:Three cases of IgA kappa cold agglutinins (CAs) were studied. One had anti-Pr1 specificity, one had anti-Pra, and one had anti-Sa. The CAs recognize O-glycans of glycophorins. The findings supplement previous data on anti-Pr1 specificities of four IgA kappa CAs. Because all IgA kappa CAs described recognize O-glycans ...

journal_title：Transfusion

authors： Roelcke D,Hack H,Kreft H,MacDonald B,Pereira A,Habibi B

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:AABB Standard 5.27 requires transfusion services to have a process for urgent release of blood before completion of compatibility testing. Our institution endorses a policy for the emergency release of group O, D+ red blood cells (RBC; O+ RBC) to males and females at least 50 years of age. Our emergency depa...

journal_title：Transfusion

authors： Meyer E,Uhl L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:RBC components collected from donors with sickle cell trait frequently occlude WBC-reduction filters. In vitro, sickle trait RBCs have the potential for sickle Hb (Hb S) polymerization at low oxygen saturations and high Hb concentrations. STUDY DESIGN AND METHOD:To determine if the low pH and high osmolarit...

journal_title：Transfusion

authors： Stroncek DF,Rainer T,Sharon V,Byrne KM,Noguchi CT,Klein HG,Schechter AN,Leitman SF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Current national standards for pretransfusion testing do not address the frequency or optimal time interval to repeat antibody identification testing for patients in whom antibodies have been previously detected. STUDY DESIGN AND METHODS:A retrospective review was performed of patients with existing red blo...

journal_title：Transfusion

authors： Dinh A,Eliason K,Dzik WS

更新日期：2019-02-01 00:00:00

abstract：:Simple methods have been developed for adding and removing glycerol during freeze-preservation with 20 per cent W/V glycerol at minus 150 C, or with 40 per cent W/V glycerol at minus 80 C. A one-step method with a 35 per cent W/V glycerol solution is used to prepare 20 per cent W/V glycerolized red blood cells, and a ...

journal_title：Transfusion

authors： Valeri CR

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：:This study evaluated various algorithms for the generation of a red cell antibody identification panel by computer. The algorithms depended on schemes that optimized Fisher's exact p value for each specificity in the panel rather than using predetermined formulations of desired phenotypic combinations. Panels produced...

journal_title：Transfusion

authors： AuBuchon JP,Roberts GC

更新日期：1987-01-01 00:00:00

abstract：:Obstetric hemorrhage is a leading cause of maternal and perinatal mortality worldwide. Intraoperative blood salvage is common practice in many surgical specialties but its safety in obstetrics is questioned for concerns on the risks of contamination of recovered blood with amniotic fluid (AF) and of maternal-fetal all...

journal_title：Transfusion

authors： Liumbruno GM,Liumbruno C,Rafanelli D

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:In 1999, NAT of blood donations was implemented to detect "window-period" infections. Blood donors who have confirmed NAT results positive for the presence of HCV in the absence of anti-HCV are likely to have been recently infected. Of over 26.8 million donations tested between March 3, 1999, and March 31, 2...

journal_title：Transfusion

authors： Orton SL,Stramer SL,Dodd RY,Alter MJ

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The Le(a) and Le(b) antigens are synthesized by cells making exocrine secretions, but it is not well-defined where plasma and red cell Le(a) and Le(b) antigens are made. STUDY DESIGN AND METHODS:This study uses chromatographic and immunochemical methods to extract Le(a) and Le(b) glycolipids from human tiss...

journal_title：Transfusion

authors： Hauser R

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:In 2010, health care facilities in the United States began voluntary enrollment in the National Healthcare Safety Network (NHSN) Hemovigilance Module. Participants report transfusion practices; red blood cell, platelet (PLT), plasma, and cryoprecipitate units transfused; and transfusion-related adverse react...

journal_title：Transfusion

authors： Harvey AR,Basavaraju SV,Chung KW,Kuehnert MJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The 2000 Nationwide Blood Collection and Utilization Survey was designed to assess cellular therapy product services in US blood centers and hospitals. STUDY DESIGN AND METHODS:Questionnaires were returned by 2,040 institutions. Data were analyzed for 30 quantitative variables related to cellular therapy pr...

journal_title：Transfusion

authors： Read EJ,Sullivan MT

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The NOD/SCID mouse is a widely used model for human cord blood (CB) transplantation. Engraftment is generally estimated with semiquantitative methods, measuring the percentage of human cells among mouse cells. To compare protocols aiming to improve hematopoietic recovery, quantitative methods to enumerate hu...

journal_title：Transfusion

authors： Schipper LF,van Hensbergen Y,Fibbe WE,Brand A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Effective risk communication in transfusion medicine is important for health-care consumers, but understanding the numerical magnitude of risks can be difficult. The objective of this study was to determine the effect of a visual risk communication tool on the knowledge and perception of transfusion risk. S...

journal_title：Transfusion

authors： Lee DH,Mehta MD

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Recently, a quasi-lipid-enveloped (LE) form of the traditionally nonlipid-enveloped (NLE) hepatitis A virus (HAV) was described in human serum and cell culture-derived HAV stocks. This discovery challenges the understanding of HAV reduction in virus clearance studies of plasma products, which were performed ...

journal_title：Transfusion

authors： Kapsch AM,Farcet MR,Antoine G,Kreil TR

更新日期：2017-06-01 00:00:00

abstract：:The supernatant plasma which remains after cryoprecipitation is a useful component for transfusion therapy. However, from prior studies it was unclear how well plasma clotting factors were preserved following cryoprecipitation. Coagulation factor assays were performed on fresh plasma, supematant plasma after removal o...

journal_title：Transfusion

authors： Roth GJ,Tobias KI

更新日期：1974-03-01 00:00:00

abstract：BACKGROUND:Human herpesvirus 8 (HHV-8) is a gamma-herpesvirus that causes Kaposi's sarcoma. The prevalence of HHV-8 genomes in US blood donors has not been systemically studied. STUDY DESIGN AND METHODS:A sensitive and quantitative real-time polymerase chain reaction (PCR) assay was used to detect HHV-8 DNA from purif...

journal_title：Transfusion

authors： Qu L,Jenkins F,Triulzi DJ

更新日期：2010-05-01 00:00:00

abstract：:Soft and hard-packed red blood cells in four different CPD anticoagulant-preservative solutions were stored with and without added glucose, adenine, and electrolytes. The hemoglobin-oxygen affinity of the red blood cell concentrates was tested over a six-week storage period. No single solution conferred better protect...

journal_title：Transfusion

authors： Wells RM,Hill RS,Woodfield DG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:This multicenter study was performed to evaluate the efficiency of a multiplex individual-donation nucleic acid amplification technology (ID-NAT) and discriminatory testing algorithm for detecting hepatitis B virus (HBV) infection in Chinese blood donors. STUDY DESIGN AND METHODS:A total of 1,205,796 hepati...

journal_title：Transfusion

authors： Gou H,Pan Y,Ge H,Zheng Y,Wu Y,Zeng J,Yang Z,Pan T,Cun W,Zhou G,Fang G,Zhang J,Zhang K,Zhang R,Sun Y,Xie J,Li J,Wang L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Tissue hypoxia and reperfusion induce abnormal hemostatic function. Therefore, bleeding after total knee replacement (TKR) may be a result of a tourniquet-induced imbalance of the procoagulant and fibrinolytic systems. Because laboratory confirmation of tourniquet-induced abnormal hemostasis is difficult to ...

journal_title：Transfusion

authors： Zohar E,Fredman B,Ellis MH,Ifrach N,Stern A,Jedeikin R

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:On rare occasions, upon thawing of stored cryoprecipitate components, clots are observed on visual inspection. Although it has been assumed that the clot reflects fibrinogen to fibrin conversion, there are few published studies that document that this assumption is correct. Our studies were conducted to furt...

journal_title：Transfusion

authors： MacPhee M,Wilmer B,Beall D,Moroff G

更新日期：2013-03-01 00:00:00

abstract：:A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

journal_title：Transfusion

authors： Ellisor SS,Shoemaker MM,Reid ME

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Red blood cells (RBCs) undergo changes during storage. Various studies have suggested a higher risk of adverse and often multifactorial clinical outcomes associated with older-stored RBCs. Our aim therefore was to examine if storage of transfused RBCs is also associated with the risk of RBC-specific alloanti...

journal_title：Transfusion

authors： Zalpuri S,Schonewille H,Middelburg R,van de Watering L,de Vooght K,Zimring J,van der Bom JG,Zwaginga JJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Transfusion-associated Chagas' disease (TA-CD) is a worldwide problem. Measures adopted to prevent TA-CD include the clinical and serologic screening of blood donors and/or the inactivation of Trypanosoma cruzi present in collected blood, using gentian violet as the trypanocidal agent. This study investigate...

journal_title：Transfusion

authors： Moraes-Souza H,Bordin JO,Bardossy L,MacPherson DW,Blajchman MA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The Q fever outbreaks in the Netherlands in 2007 to 2009 initiated discussion on the necessity of measures to prevent transmission through blood products. Risk assessments help transfusion regulators decide when and where measures are required. This study assesses the transfusion transmission (TT) risk of Q ...

journal_title：Transfusion

authors： Oei W,Kretzschmar ME,Zaaijer HL,Coutinho R,van der Poel CL,Janssen MP

更新日期：2014-07-01 00:00:00