Le(a) and Le(b) tissue glycosphingolipids.

Abstract:

BACKGROUND:The Le(a) and Le(b) antigens are synthesized by cells making exocrine secretions, but it is not well-defined where plasma and red cell Le(a) and Le(b) antigens are made. STUDY DESIGN AND METHODS:This study uses chromatographic and immunochemical methods to extract Le(a) and Le(b) glycolipids from human tissues. RESULTS:Le(a) and Le(b) antigens may be synthesized by both epithelial and mesodermal tissues. Expression of Lewis transferase activity was demonstrated in various tissues, confirming the epistatic interaction by Le and H genes to form the Leb antigen. CONCLUSION:The Le(a) and Le(b) substances found in plasma might originate from the epithelial cells of the digestive tract.

journal_name

Transfusion

journal_title

Transfusion

authors

Hauser R

doi

10.1046/j.1537-2995.1995.35795357880.x

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

577-81

issue

7

eissn

0041-1132

issn

1537-2995

journal_volume

35

pub_type

杂志文章
  • Collection of white blood cell-reduced plasma by apheresis.

    abstract:BACKGROUND:WBC reduction of cellular blood components has been introduced in many countries. Owing to concerns of residual WBCs in plasma, a new method to collect WBC-reduced plasma by apheresis was studied. STUDY DESIGN AND METHODS:An apheresis machine (PCS2, Haemonetics) was used, in combination with the "high-separ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03314.x

    authors: Vrielink H,van der Meer PF

    更新日期:2004-06-01 00:00:00

  • Incomplete pretransfusion testing leads to surgical delays.

    abstract:BACKGROUND:The Joint Commission has highlighted the importance of having appropriate and complete pretransfusion testing before surgery begins. The maximum surgical blood ordering schedule (MSBOS) indicates which patients require preoperative transfusion testing. We determined the number of times surgical delays were c...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03568.x

    authors: McWilliams B,Yazer MH,Cramer J,Triulzi DJ,Waters JH

    更新日期:2012-10-01 00:00:00

  • Stability after thawing of RBCs frozen with the high- and low-glycerol method.

    abstract:BACKGROUND:RBCs can be frozen with either the high-glycerol method (HGM) or the low-glycerol method (LGM). To date, the use of frozen RBCs is hampered by a 24-hour outdating period after thawing. A closed washing system (ACP 215) may solve this problem. STUDY DESIGN AND METHODS:We compared the effects of high- (40%) a...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00293.x

    authors: Lelkens CC,Noorman F,Koning JG,Truijens-de Lange R,Stekkinger PS,Bakker JC,Lagerberg JW,Brand A,Verhoeven AJ

    更新日期:2003-02-01 00:00:00

  • Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits.

    abstract:BACKGROUND:Research with primary human white blood cell (WBC) subpopulations requires high quantity, quality, and functionality of peripheral blood mononuclear cells (PBMCs) as a source to further characterize cellular subpopulations such as T and B lymphocytes, monocytes, or natural killer cells. Apart from buffy coat...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14616

    authors: Knörck A,Marx S,Friedmann KS,Zöphel S,Lieblang L,Hässig C,Müller I,Pilch J,Sester U,Hoth M,Eichler H,Sester M,Schwarz EC

    更新日期:2018-06-01 00:00:00

  • Human T-lymphotropic virus type I and type II infections and correlation with risk factors in blood donors from São Paulo, Brazil.

    abstract:BACKGROUND:Little is known about the prevalence of and risk factors for human T-lymphotropic virus type I and type II (HTLV-I, HTLV-II) infections in Brazil. STUDY DESIGN AND METHODS:Sera from 17,063 healthy Brazilian donors were screened by enzyme-linked immunosorbent assay for antibody to HTLV-I/II between August 19...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1995.35395184284.x

    authors: Ferreira Júnior OC,Vaz RS,Carvalho MB,Guerra C,Fabron AL,Rosemblit J,Hamerschlak N

    更新日期:1995-03-01 00:00:00

  • Duration of red blood cell storage and survival of transfused patients (CME).

    abstract:BACKGROUND:Disquieting reports of increased complication and death rates after transfusions of red blood cells (RBCs) stored for more than 14 days prompted us to perform an observational retrospective cohort study of mortality in relation to storage time. STUDY DESIGN AND METHODS:We conducted a cohort study utilizing ...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1537-2995.2010.02583.x

    authors: Edgren G,Kamper-Jørgensen M,Eloranta S,Rostgaard K,Custer B,Ullum H,Murphy EL,Busch MP,Reilly M,Melbye M,Hjalgrim H,Nyrén O

    更新日期:2010-06-01 00:00:00

  • Transfusion of murine red blood cells expressing the human KEL glycoprotein induces clinically significant alloantibodies.

    abstract:BACKGROUND:Red blood cell (RBC) alloantibodies to nonself antigens may develop after transfusion or pregnancy, leading to morbidity and mortality in the form of hemolytic transfusion reactions or hemolytic disease of the newborn. A better understanding of the mechanisms of RBC alloantibody induction, or strategies to m...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12217

    authors: Stowell SR,Girard-Pierce KR,Smith NH,Henry KL,Arthur CM,Zimring JC,Hendrickson JE

    更新日期:2014-01-01 00:00:00

  • Platelet glycolytic flux increases stimulated by ultraviolet-induced stress is not the direct cause of platelet morphology and activation changes: possible implications for the role of glucose in platelet storage.

    abstract:BACKGROUND:Stress-enhanced platelet (PLT) storage lesions include increased glycolysis, discoid-to-sphere morphology change, and spontaneous PLT activation. It is not clear if reduction in glycolysis can alleviate storage lesion development. STUDY DESIGN AND METHODS:Apheresis PLT concentrates were exposed to 17.2 J/mL...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00582.x

    authors: Li J,Goodrich L,Hansen E,Edrich R,Gampp D,Goodrich RP

    更新日期:2005-11-01 00:00:00

  • The impact of e-mail in acquiring and retaining whole-blood donors: a comparative analysis of the Puget Sound Blood Center donor e-mail communication program.

    abstract:BACKGROUND:With the emergence of e-mail as a common form of communication, it is important to understand the role and impact e-mail can have on acquiring and retaining whole-blood donors. STUDY DESIGN AND METHODS:Whole-blood donors who opted in to receive e-mail communications (n = 43,232) from the Puget Sound Blood C...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00642.x

    authors: Geyer ME

    更新日期:2005-12-01 00:00:00

  • Hematology patterns after hemoglobin-based oxygen carrier resuscitation from severe controlled hemorrhage with prolonged delayed definitive care.

    abstract:BACKGROUND:The hemoglobin-based oxygen carrier (HBOC-201) resuscitation fluid improves outcome in hemorrhagic shock swine models with minimal coagulopathy. Herein, coagulation parameters were evaluated after resuscitation with HBOC-201 after severe bleeding and prolonged delay to definitive care. STUDY DESIGN AND METH...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01435.x

    authors: Arnaud F,Fasipe D,Philbin N,Rice J,Flournoy WS,Ahlers S,McCarron R,Freilich D

    更新日期:2007-11-01 00:00:00

  • How we treat: transfusion medicine support of obstetric services.

    abstract:BACKGROUND:Obstetric services depend on the transfusion service (TS) to provide diagnostic testing and blood component therapy for clinical care pathways. STUDY DESIGN AND METHODS:We describe three quality improvement (QI) initiatives implemented to improve TS support of obstetric services. RESULTS:We implemented a p...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2011.03152.x

    authors: Goodnough LT,Daniels K,Wong AE,Viele M,Fontaine MF,Butwick AJ

    更新日期:2011-12-01 00:00:00

  • Ranking the effectiveness of autologous blood conservation measures through validated modeling of independent clinical data.

    abstract:BACKGROUND:Future supply with allogeneic blood transfusions faces several crucial challenges that warrant thorough (re-)evaluation of existing alternatives. Meta-analyses have indicated a significant potential for autologous blood conservation (ABC) measures to reduce the need for allogeneic blood transfusions. The qua...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12233

    authors: Singbartl G,Held AL,Singbartl K

    更新日期:2013-12-01 00:00:00

  • Comparison and stability of ADAMTS13 activity in therapeutic plasma products.

    abstract:BACKGROUND:The von Willebrand factor (VWF)-cleaving protease, ADAMTS13, is often deficient in cases of thrombotic thrombocytopenic purpura (TTP). The primary treatment of TTP is therapeutic plasma exchange (TPE) utilizing a variety of plasma products that help restore ADAMTS13 activity. However, multiple replacement pr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01074.x

    authors: Scott EA,Puca KE,Pietz BC,Duchateau BK,Friedman KD

    更新日期:2007-01-01 00:00:00

  • Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation.

    abstract:BACKGROUND:The successful mobilization and collection of hematopoietic stem cells are dependent on a number of clinical factors such as previous chemotherapy and disease stage. The aim of this retrospective study was to determine whether the effectiveness of mobilization and collection is an independent prognostic fact...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01448.x

    authors: Wang S,Nademanee A,Qian D,Dagis A,Park HS,Fridey J,Smith E,Snyder D,Somlo G,Stein A,Rosenthal J,Falk P,Kogut N,Palmer J,Gaal K,Kim Y,Bhatia R,Yuan S,Kay C,Weiss L,Forman S

    更新日期:2007-12-01 00:00:00

  • Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome.

    abstract:BACKGROUND:There is controversy regarding the application of transfusion triggers in cardiac surgery. The goal of this study was to determine if lowering the hemoglobin threshold for red cell (RBC) transfusion to 8 g per dL after coronary artery bypass graft surgery would reduce blood use without adversely affecting pa...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1537-2995.1999.39101070.x

    authors: Bracey AW,Radovancevic R,Riggs SA,Houston S,Cozart H,Vaughn WK,Radovancevic B,McAllister HA Jr,Cooley DA

    更新日期:1999-10-01 00:00:00

  • Emm. A red cell antigen of very high frequency.

    abstract::Anti-Emm, an antibody to a public red cell antigen, was found in the serums of four Emm-propositi and in the serum of the Emm-brother of one of them. Three of the propositi were men, and their antibodies, as well as that of the compatible brother, were believed to be "naturally occurring." Since there are two Emm-sibl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27487264738.x

    authors: Daniels GL,Taliano V,Klein MT,McCreary J

    更新日期:1987-07-01 00:00:00

  • Synchronous development of acute myeloid leukemia in recipient and donor after allogeneic bone marrow transplantation: report of a case with comments on donor evaluation.

    abstract:BACKGROUND:A case of donor cell leukemia (DCL) is reported. A 42-year-old female developed acute myeloid leukemia (AML) of donor cell origin 18 months after a bone marrow transplant (BMT) from her brother. At the time DCL presented, the donor-brother was also diagnosed with AML showing identical cytogenetic abnormaliti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.02008.x

    authors: Glasser L,Meloni-Ehrig A,Greaves W,Demel KC,Butera J

    更新日期:2009-03-01 00:00:00

  • Hypericin as an inactivator of infectious viruses in blood components.

    abstract:BACKGROUND:Hypericin is a potent virucidal agent with activity against a broad range of enveloped viruses and retroviruses. The effective virucidal activity emanates from a combination of photodynamic and lipophilic properties. Hypericin binds cell membranes (and, by inference, virus membranes) and crosslinks virus cap...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1995.35595259149.x

    authors: Lavie G,Mazur Y,Lavie D,Prince AM,Pascual D,Liebes L,Levin B,Meruelo D

    更新日期:1995-05-01 00:00:00

  • Analysis of exome sequencing data sets reveals structural variation in the coding region of ABO in individuals of African ancestry.

    abstract:BACKGROUND:ABO is a blood group system of high clinical significance due to the prevalence of ABO variation that can cause major, potentially life-threatening, transfusion reactions. STUDY DESIGN AND METHODS:Using multiple large-scale next-generation sequence data sets, we demonstrate the application of read-depth app...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13797

    authors: Fox K,Johnsen JM,Coe BP,Frazar CD,Reiner AP,NHLBI Exome Sequencing Project, Minority Health-GRID Network.,Eichler EE,Nickerson DA

    更新日期:2016-11-01 00:00:00

  • Anti-Ytb in pregnancy.

    abstract::Anti-Ytb was readily eluted from the cord red blood cells of the second child of a mother with both anti-Ytb and anti-Kell in her serum. The baby was Yt (a+b+) and Kell negative. The cord red blood cells were found to have a weakly positive direct antiglobulin test. Clinically evident hemolytic disease of the newborn ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1979.19580059814.x

    authors: Ferguson SJ,Boyce F,Blajchman MA

    更新日期:1979-09-01 00:00:00

  • Hemolysis in patients with antibody deficiencies on immunoglobulin replacement treatment.

    abstract:BACKGROUND:Immunoglobulin (Ig)G replacement with intravenous or subcutaneous immunoglobulins is a lifelong substitutive therapy in patients with primary antibody deficiencies (PADs). Hemolysis after immunoglobulin therapy was described in patients receiving high immunoglobulin dosages. The issue of hemolysis after immu...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12939

    authors: Quinti I,Pulvirenti F,Milito C,Granata G,Giovannetti G,La Marra F,Pesce AM,Farrugia A,Coluzzi S,Girelli G

    更新日期:2015-05-01 00:00:00

  • Antibodies to co-trimoxazole (trimethoprim and/or sulfamethoxazole) related to the presence of the drug in a commercial low-ionic-strength solution.

    abstract:BACKGROUND:Drug-dependent antibodies have been associated with approximately 10% of acquired immune hemolytic anemia cases. These antibodies are a rare cause of interference in pretransfusion red blood cell (RBC) serologic testing. The aim of this work was to report three cases of subjects developing antibodies against...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03327.x

    authors: Pham BN,Gien D,Bensaad F,Babinet J,Dubeaux I,Rouger P,Le Pennec PY

    更新日期:2012-04-01 00:00:00

  • Calcium is a key constituent for maintaining the in vitro properties of platelets suspended in the bicarbonate-containing additive solution M-sol with low plasma levels.

    abstract:BACKGROUND:Commercially available additive solutions (ASs) require 30% to 35% plasma for optimal storage of platelets (PLTs). PLTs suspended in M-sol, a bicarbonate-based experimental platelet additive solution (PAS), maintain in vitro PLT properties during storage with low levels of plasma (< or =5%). STUDY DESIGN AN...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02539.x

    authors: Wagner SJ,Skripchenko A,Myrup A,Thompson-Montgomery D,Awatefe H,Moroff G

    更新日期:2010-05-01 00:00:00

  • Depletion of white cells from platelet concentrates with a new adsorption filter.

    abstract::Removal of white cells (WBCs) from platelets may reduce alloimmunization to WBC antigens, prevent febrile reactions, and improve platelet increments in multiply transfused patients receiving HLA-matched platelets. A new surface-modified fibrous polyester filter was evaluated; it requires no special processing of poole...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1989.29589284140.x

    authors: Kickler TS,Bell W,Drew H,Pall D

    更新日期:1989-06-01 00:00:00

  • Development of a validated exam to assess physician transfusion medicine knowledge.

    abstract:BACKGROUND:There is evidence that physicians lack adequate transfusion medicine knowledge. To design needs-based educational interventions to address this gap, a validated assessment tool is required. Previously published exams have not been created or validated using rigorous psychometric methods. STUDY DESIGN AND ME...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12425

    authors: Haspel RL,Lin Y,Fisher P,Ali A,Parks E,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

    更新日期:2014-05-01 00:00:00

  • Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease.

    abstract:BACKGROUND:Despite the clinical significance of red blood cell (RBC) alloantibodies, there are currently no laboratory tests available to predict which patients may be at risk of antibody formation after transfusion exposure. Given their phagocytic and inflammatory functions, we hypothesized that differences in circula...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15463

    authors: Balbuena-Merle R,Curtis SA,Devine L,Gibb DR,Karafin MS,Luckey CJ,Tormey CA,Siddon AJ,Roberts JD,Hendrickson JE

    更新日期:2019-10-01 00:00:00

  • Sampling errors and the precision associated with counting very low numbers of white cells in blood components.

    abstract::Attention to the accurate and precise measurement of the white cell (WBC) content of transfused products has risen in response to awareness of the potential benefits of WBC-depleted components and the development of technical capabilities to produce these components. The techniques thus far reported have focused on th...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31591263198.x

    authors: Dumont LJ

    更新日期:1991-06-01 00:00:00

  • In vivo and in vitro characteristics of double units of RBCs collected by apheresis with a single in-line WBC-reduction filter.

    abstract:BACKGROUND:A novel apheresis procedure for a blood separator (MCS+, Haemonetics) enables the collection of 2 WBC-reduced RBC units in a single donation by using one disposable set with one in-line WBC-reduction filter (RC2H, Pall Corp.). The objective of this study was to evaluate the filtration performance in connecti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41111373.x

    authors: Bandarenko N,Rose M,Kowalsky RJ,Baston RK,Brecher ME,Elfath MD,Whitley P,Heminway M,Holme S

    更新日期:2001-11-01 00:00:00

  • Association of ABO blood group with P-selectin levels in Chinese Han healthy volunteers.

    abstract:BACKGROUND:Recent genome-wide association studies in Caucasians suggested that an association exists between the ABO gene locus and soluble levels of P-selectin (sP-selectin). However, it is unclear if the relationship corresponds to the phenotypic expression of ABO groups or is present in different ethnic groups. The ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13212

    authors: Chen Y,Zhuo X,Lin Y,Huang W,Xiao J,Zeng J,Jiang L,Chen C,Lin H,Dettke M

    更新日期:2015-11-01 00:00:00

  • Effect of storage time and donor sex of transfused red blood cells on 1-year survival in patients undergoing cardiac surgery: an observational study.

    abstract:BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/trf.13537

    authors: Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

    更新日期:2016-05-01 00:00:00