Comparison and stability of ADAMTS13 activity in therapeutic plasma products.

abstract：BACKGROUND:Blood components are often given prophylactically before the placement of invasive lines in patients with coagulation defects. Little, however, is known about the epidemiology of defects in these patients. The purpose of this study is to ascertain what proportion of intensive care patients who receive invasi...

journal_title：Transfusion

authors： DeLoughery TG,Liebler JM,Simonds V,Goodnight SH

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Biological and technical variability has been increasingly appreciated as a key factor impacting red blood cell (RBC) storability and, potentially, transfusion outcomes. Here, we performed metabolomics analyses to investigate the impact of factors other than storage duration on the metabolic phenotypes of st...

journal_title：Transfusion

authors： D'Alessandro A,Culp-Hill R,Reisz JA,Anderson M,Fu X,Nemkov T,Gehrke S,Zheng C,Kanias T,Guo Y,Page G,Gladwin MT,Kleinman S,Lanteri M,Stone M,Busch M,Zimring JC,Recipient Epidemiology and Donor Evaluation Study-III (REDS-

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Endothelial cells (ECs) play a pivotal role in the allogeneic immune response upon transplantation. Semaphorin 3A (Sema3A) was implicated in the modulation of EC growth, but its effects on immunogenicity were not previously investigated. STUDY DESIGN AND METHODS:ECs were transduced with a lentiviral vector ...

journal_title：Transfusion

authors： Schlahsa L,Zhang H,Battermann A,Verboom M,Immenschuh S,Eiz-Vesper B,Stripecke R,Engelmann K,Blasczyk R,Figueiredo C

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:In cases of warm autoimmune hemolytic anemia (WAIHA), crossmatch incompatible RBCs are most often used for transfusion. The determination of the in vivo survival of transfused and autologous RBCs in WAIHA is helpful in the assessment of the efficacy of transfusion and other therapeutic interventions. CASE R...

journal_title：Transfusion

authors： Zeiler T,Müller JT,Hasse C,Kullmer J,Kretschmer V

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...

journal_title：Transfusion

authors： Ramirez-Arcos S,Evans S,McIntyre T,Pang C,Yi QL,DiFranco C,Goldman M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Sickle cell disease (SCD) is associated with hematologic complications including delayed hemolytic transfusion reactions (DHTRs) and pregnancy-related morbidity and mortality. Hyperhemolysis syndrome (HS) is the most severe form of DHTR in patients with SCD, in which both transfused and native red blood cell...

journal_title：Transfusion

authors： Vasanthamohan L,Choo S,Marshall T,Symons YT,Matsui D,Eastabrook G,Solh Z

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Factor (F)XIII deficiency is a rare inherited bleeding disorder, but can also be acquired due to the development of inhibitors. CASE REPORT:A 17-year-old female with systemic lupus erythematosus and end-stage kidney disease secondary to Class IV lupus nephritis developed spontaneous subcutaneous and muscula...

journal_title：Transfusion

authors： Rabik CA,Atkinson MA,Sule S,Strouse JJ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

journal_title：Transfusion

authors： Fuller AK,Uglik KM,Braine HG,King KE

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：:Red cells from a Mexican blood donor had depressed H, IF, ID, i, Sda, Sdx, D, LW, Dib, Vel and JMH antigens. A wide range of other blood group antigens had normal activity. The unusual red cell phenotype may be caused by a membrane anomaly that alters orientation of certain cell surface components. The specificities o...

journal_title：Transfusion

authors： Biro V,Garratty G,Johnson CL,Marsh WL

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Tissue hypoxia and reperfusion induce abnormal hemostatic function. Therefore, bleeding after total knee replacement (TKR) may be a result of a tourniquet-induced imbalance of the procoagulant and fibrinolytic systems. Because laboratory confirmation of tourniquet-induced abnormal hemostasis is difficult to ...

journal_title：Transfusion

authors： Zohar E,Fredman B,Ellis MH,Ifrach N,Stern A,Jedeikin R

更新日期：2001-10-01 00:00:00

abstract：:We report here the results of our evaluation of two procedures to eliminate viruses in factor VIII and factor IX coagulation factor concentrates. Both procedures were equally effective in the in vitro destruction of marker viruses. However, in a controlled infectivity test in chimpanzees, treatment at 60 degrees C for...

journal_title：Transfusion

authors： Heldebrant CM,Gomperts ED,Kasper CK,McDougal JS,Friedman AE,Hwang DS,Muchmore E,Jordan S,Miller R,Sergis-Davenport E

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:In sub-Saharan Africa (SSA) confirmed viral marker prevalence between family donors (FDs) and first-time volunteer nonremunerated donors (VNRDs) is similar. In a blood service collecting 10 units/1000 inhabitants, a questionnaire examined FD donation conditions and willingness of becoming repeat VNRDs. STUD...

journal_title：Transfusion

authors： Asenso-Mensah K,Achina G,Appiah R,Owusu-Ofori S,Allain JP

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:In the Rh blood group system, variant RhD and RhCE express several partial antigens. We investigated RH in samples with partial DIVa that demonstrated weak and variable reactivity with anti-C. STUDY DESIGN AND METHODS:Standard hemagglutination techniques, polymerase chain reaction-based assays, and RH seque...

journal_title：Transfusion

authors： Westhoff CM,Vege S,Halter Hipsky C,Hue-Roye K,Copeland T,Velliquette RW,Horn T,Lomas-Francis C,Reid ME

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Platelets (PLTs) contain purinergic receptors for ATP (P2X1) and ADP (P2Y1 and P2Y12) that rapidly desensitize upon stimulation with these nucleotides. In vivo, this is antagonized by ectonucleotidases on the surface of endothelial cells and white blood cells (WBCs). The receptor desensitization of ATP- and ...

journal_title：Transfusion

authors： Cauwenberghs S,Feijge MA,Hageman G,Hoylaerts M,Akkerman JW,Curvers J,Heemskerk JW

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Retrospective studies suggested that storage age of RBCs is associated with inflammation and thromboembolism. The Red Cell Storage Duration Study (RECESS) trial randomized subjects undergoing complex cardiac surgery to receive RBCs stored for shorter versus longer periods, and no difference was seen in the p...

journal_title：Transfusion

authors： Spinella PC,Sniecinski RM,Trachtenberg F,Inglis HC,Ranganathan G,Heitman JW,Szlam F,Danesh A,Stone M,Keating SM,Levy JH,Assmann SF,Steiner ME,Doctor A,Norris PJ

更新日期：2019-04-01 00:00:00

abstract：:Tunneled central venous catheters with ports are increasingly used for therapeutic apheresis procedures. Vortex ports have been used as access for therapeutic apheresis procedures, but are not ideal for therapeutic plasma exchange (TPE) procedures due to lower flow rates. We performed an in vitro experiment to compare...

journal_title：Transfusion

authors： De Simone N,Sarode R

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The de novo development of anti-D after D-mismatched allogeneic hematopoietic stem cell transplantation (AHSCT) is a possibility that must be considered. The transfusion of D- blood components after AHSCT has been recommended but anti-D alloimmunization in this setting has been studied little. Thus, the aim ...

journal_title：Transfusion

authors： Cid J,Lozano M,Fernández-Avilés F,Carreras E,Pereira A,Mazzara R,Ordinas A

更新日期：2006-02-01 00:00:00

abstract：:The possible beneficial role of white cells (WBCs) in donor blood has been investigated with respect to their capacity to remove bacteria. Preparations of buffy coat and whole blood, containing as well as reduced of WBCs, were inoculated with Staphylococcus epidermidis, S. aureus, Escherichia coli, Pseudomonas aerugin...

journal_title：Transfusion

authors： Högman CF,Gong J,Eriksson L,Hambraeus A,Johansson CS

更新日期：1991-09-01 00:00:00

abstract：:Several blood transfusion filters designed to remove microemboli were evaluated for filtration and flow characteristics, as well as for hemolysis and for release of particulate debris from the filter. The Dacron wool filter, a depth filter, was superior at removing microemboli measured with an electronic particle size...

journal_title：Transfusion

authors： Kennedy PS,Solis RT,Scott MA,Wilson RK

更新日期：1977-11-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:We set out to define the impact of collection, processing, and storage on plasma product microparticle (MP) abundance, potential for nitric oxide (NO) scavenging, and vasoactivity. STUDY DESIGN AND METHODS:Three currently US licensed products were tested: liquid plasma (LP), fresh frozen plasma (FFP), and s...

journal_title：Transfusion

authors： Rogers SC,Moynihan FT 4th,McDonough R,Timm DD,Hovmand-Warner E,Frazier E,Thomas KA,Spinella PC,Doctor A

更新日期：2019-04-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00

abstract：:A 67-year-old white woman received transfusions of a total of 87 units of whole blood and red blood cells during and within 48 hours following a pneumonectomy. Although she had previously received blood transfusions, unexpected antibodies were not detectable by routine screening. On the second postoperative day, she d...

journal_title：Transfusion

authors： Chandeysson PL,Flye MW,Simpkins SM,Holland PV

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Proteomics methods may be used to analyze changes occurring in stored blood products. These data sets can identify processes leading to storage-associated losses of blood component quality such as the platelet (PLT) storage lesion (PSL). The optimal strategy to perform such analyses to obtain the most inform...

journal_title：Transfusion

authors： Thon JN,Schubert P,Duguay M,Serrano K,Lin S,Kast J,Devine DV

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The risk of transfusion reactions (TR) and the cost of blood has led to efforts to reduce blood use. We changed our practice to transfuse just one instead of two units of red blood cells (RBC) when hemoglobin ≤8 g/dL due to patient blood management (PBM) recommendations. METHODS AND MATERIALS:We compared RB...

journal_title：Transfusion

authors： Gastecki K,Shanley R,Welbig J,Cohn C,Brunstein CG

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis G virus (HGV) and its strain variant, the GB agent (GBV-C) is high in non-virus-inactivated plasma products, but, persistent infection in recipients is relatively low. STUDY DESIGN AND METHODS:Stored samples from transfusion donors and recipients in a prospective study of posttra...

journal_title：Transfusion

authors： Wang JT,Chen PJ,Liu DP,Sheu JC,Wang TH,Chen DS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery ...

journal_title：Transfusion

authors： Balint B,Paunovic D,Vucetic D,Vojvodic D,Petakov M,Trkuljic M,Stojanovic N

更新日期：2006-02-01 00:00:00