A comprehensive program to minimize platelet outdating.

Abstract:

BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs made in the United States outdated. It is imperative to have a sufficient number of products for patients requiring transfusion, but outdating PLTs is a financial burden and a waste of a resource. STUDY DESIGN AND METHODS:We present the approach used in our institution to anticipate inventory needs based on current patient census and usage. Strategies to predict usage and to identify changes in anticipated usage are examined. Annual outdating is reviewed for a 10-year period from 2000 through 2009. RESULTS:From January 1, 2000, through December 2009, there were 128,207 PLT transfusions given to 15,265 patients. The methods used to anticipate usage and adjust inventory resulted in an annual outdate rate of approximately 1% for the 10-year period reviewed. In addition we have not faced situations where inventory was inadequate to meet the needs of the patients requiring transfusions. CONCLUSION:We have identified three elements of our transfusion service that can minimize outdate: a knowledgeable proactive staff dedicated to PLT management, a comprehensive computer-based transfusion history for each patient, and a strong two-way relationship with the primary product supplier. Through our comprehensive program, based on the principles of providing optimal patient care, we have minimized PLT outdating for more than 10 years.

journal_name

Transfusion

journal_title

Transfusion

authors

Fuller AK,Uglik KM,Braine HG,King KE

doi

10.1111/j.1537-2995.2010.03039.x

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

1469-76

issue

7

eissn

0041-1132

issn

1537-2995

journal_volume

51

pub_type

杂志文章
  • Effect of storage time and donor sex of transfused red blood cells on 1-year survival in patients undergoing cardiac surgery: an observational study.

    abstract:BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/trf.13537

    authors: Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

    更新日期:2016-05-01 00:00:00

  • Epidemiological trends of HIV-1 infection in blood donors from Catalonia, Spain (2005-2014).

    abstract:BACKGROUND:Human immunodeficiency virus 1 (HIV-1) subtype B is predominant in Spain. However, the recent arrival of immigrant populations has increased the prevalence of non-B subtypes and circulating recombinant forms. The objective of this study was to determine the prevalence of HIV-1 subtypes and transmitted drug-r...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14195

    authors: Bes M,Piron M,Casamitjana N,Gregori J,Esteban JI,Ribera E,Quer J,Puig L,Sauleda S

    更新日期:2017-09-01 00:00:00

  • Red blood cell use outside the operating theater: a prospective observational study with modeling of potential blood conservation during severe blood shortages.

    abstract:BACKGROUND:National guidance recommends planning for future blood shortages, but few studies have evaluated how reduced demand could be achieved acutely. STUDY DESIGN AND METHODS:A trained observer collected data concerning red blood cell (RBC) transfusion events outside the operating theater during 68 hours of blood ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02244.x

    authors: Joseph BG,Hendry C,Walsh TS

    更新日期:2009-10-01 00:00:00

  • Trends in blood utilization in United States cardiac surgical patients.

    abstract:BACKGROUND:We sought to determine whether publication of blood conservation guidelines by the Society of Thoracic Surgeons in 2007 influenced transfusion rates and to understand how patient- and hospital-level factors influenced blood product usage. STUDY DESIGN AND METHODS:We identified 4,465,016 patients in the Nati...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12903

    authors: Robich MP,Koch CG,Johnston DR,Schiltz N,Chandran Pillai A,Hussain ST,Soltesz EG

    更新日期:2015-04-01 00:00:00

  • Rapid identification of microorganisms from platelet concentrates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry after short-term incubation on liquid medium.

    abstract:BACKGROUND:Platelets (PLTs) are especially affected by the risk of bacterial contamination. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) is an accurate method for the routine identification of bacterial isolates in microbiology laboratories. We directly applied the MALDI-TOF method to bacteria...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14430

    authors: Chetouane Y,Dubourg G,Gallian P,Flaudrops C,Chiaroni J,Chabrière E,Raoult D,Camoin-Jau L

    更新日期:2018-03-01 00:00:00

  • Infusible platelet membranes improve hemostasis in thrombocytopenic blood: experimental studies under flow conditions.

    abstract:BACKGROUND:The potential hemostatic effect of infusible platelet membranes (IPM; Cyplex, Cypress Bioscience) prepared from outdated human platelets is investigated. STUDY DESIGN AND METHODS:Increasing concentrations of IPM were added to blood samples anticoagulated with low-molecular-weight heparin, in which platelets...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40091074.x

    authors: Galán AM,Bozzo J,Hernández MR,Pino M,Reverter JC,Mazzara R,Escolar G,Ordinas A

    更新日期:2000-09-01 00:00:00

  • Hemostats, sealants, and adhesives III: a new update as well as cost and regulatory considerations for components of the surgical toolbox.

    abstract::The hemostat, sealant, and adhesive components of the surgical toolbox continue to evolve and enter clinical practice at a rapid rate. The goal of this comprehensive, sequential review is to update these components to include those now available (February 2012) as well as to explore cost and regulatory factors that im...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2012.03707.x

    authors: Spotnitz WD,Burks S

    更新日期:2012-10-01 00:00:00

  • Hemolytic disease of the newborn due to anti-Di: a case study and review of the literature.

    abstract:BACKGROUND:The severity of hemolytic disease of the newborn (HDN) due to Diego(b) (Di(b)) mismatch ranges from no symptoms to severe jaundice that requires exchange transfusion (ET). The clinical significance of anti-Di(b) is incompletely recognized. CASE REPORT:A male newborn, referred with jaundice, was revealed to ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.00743.x

    authors: Mochizuki K,Ohto H,Hirai S,Ujiie N,Amanuma F,Kikuta A,Miura S,Yasuda H,Ishijima A,Suzuki H

    更新日期:2006-03-01 00:00:00

  • Down regulation of human natural killer cell-mediated cytolysis induced by blood transfusion: role of transforming growth factor-β(1), soluble Fas ligand, and soluble Class I human leukocyte antigen.

    abstract:BACKGROUND:Human natural killer (NK) cells are thought to play a role in antiviral response and tumor immune surveillance. The molecular mechanisms of down regulation of NK-cell activity observed after red blood cell (RBC) transfusion is still undefined. STUDY DESIGN AND METHODS:Both effects of blood transfusion (ex v...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03000.x

    authors: Ghio M,Contini P,Negrini S,Mazzei C,Zocchi MR,Poggi A

    更新日期:2011-07-01 00:00:00

  • Evaluation of the National Healthcare Safety Network Hemovigilance Module for transfusion-related adverse reactions in the United States.

    abstract:INTRODUCTION:The National Healthcare Safety Network (NHSN) Hemovigilance Module (HM) collects data on the frequency, severity, and imputability of transfusion-associated adverse events. These events contribute to significant morbidity and mortality among transfusion patients. We report results from the first systematic...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15008

    authors: Edens C,Haass KA,Cumming M,Osinski A,O'Hearn L,Passanisi K,Eaton L,Visintainer P,Savinkina A,Kuehnert MJ,Basavaraju SV,Andrzejewski C

    更新日期:2019-02-01 00:00:00

  • Recipients of blood from a donor with multiple HLA antibodies: a lookback study of transfusion-related acute lung injury.

    abstract:BACKGROUND:The effects of transfusion of HLA antibodies to patients with corresponding antigens are not well known. STUDY DESIGN AND METHODS:Records of patients who received blood from previous donations of a donor implicated in a case of transfusion-related acute lung injury (TRALI) were examined. The donor had multi...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.0041-1132.2004.04193.x

    authors: Toy P,Hollis-Perry KM,Jun J,Nakagawa M

    更新日期:2004-12-01 00:00:00

  • A review of blood donor motivation and recruitment.

    abstract::Sixty English-language articles on the motivation and recruitment of blood donors and nondonors are reviewed and evaluated. Apparently researchers have been finding essentially the same results for approximately twenty years. Motivations to donate are: altruism/humanitarian, personal or family credit, social pressure,...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17277151916.x

    authors: Oswalt RM

    更新日期:1977-03-01 00:00:00

  • Is current serologic RhD typing of blood donors sufficient for avoiding immunization of recipients?

    abstract:BACKGROUND:Avoiding immunization with clinically important antibodies is a primary objective in transfusion medicine. Therefore, it is central to identify the extent of D antigens that escape routine RhD typing of blood donors and to improve methodology if necessary. STUDY DESIGN AND METHODS:We screened 5058 D- donors...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03156.x

    authors: Krog GR,Clausen FB,Berkowicz A,Jørgensen L,Rieneck K,Nielsen LK,Dziegiel MH

    更新日期:2011-11-01 00:00:00

  • Prestorage universal WBC reduction of RBC units does not affect the incidence of transfusion reactions.

    abstract:BACKGROUND:Febrile nonhemolytic transfusion reaction (FNHTR) has been identified as a pivotal reason for prestorage universal WBC reduction. A regional blood center implemented universal prestorage WBC reduction for RBCs on January 1, 2000. Whether prestorage universal WBC reduction of RBC units will affect FNHTR is no...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41080997.x

    authors: Uhlmann EJ,Isgriggs E,Wallhermfechtel M,Goodnough LT

    更新日期:2001-08-01 00:00:00

  • NAT screening of blood donors for severe acute respiratory syndrome coronavirus can potentially prevent transfusion associated transmissions.

    abstract:BACKGROUND:The severe acute respiratory syndrome (SARS) was first described in February 2003. Close contact with symptomatic patients appears to be the main route of transmission, whereas blood transfusion transmission could not be ruled out. STUDY DESIGN AND METHODS:A SARS coronavirus (SARS-CoV) detection kit develop...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03269.x

    authors: Schmidt M,Brixner V,Ruster B,Hourfar MK,Drosten C,Preiser W,Seifried E,Roth WK

    更新日期:2004-04-01 00:00:00

  • Clinical outcomes and transfusion management following intracranial hemorrhage in patients with acute leukemia.

    abstract:BACKGROUND:There is little evidence to guide management of patients with acute leukemia and intracranial hemorrhage (ICH). Predictors of long-term outcome following ICH are unknown. STUDY DESIGN AND METHODS:This study included adult patients with acute leukemia and ICH over an 8-year period. The primary outcome was da...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15621

    authors: Nixon S,Lieberman L,Atenafu EG,Doherty M,Murray C,Wolfe A,Brandys D,Rowland S,Kwan BY,Yu E,Lechner B,Maze D

    更新日期:2020-02-01 00:00:00

  • Enhanced HPC recruitment in children using LVL and a new automated apheresis system.

    abstract:BACKGROUND:A new automated apheresis system has recently been reported as useful in improving peripheral blood HPC collection in adults. The aim of this study has been to verify the utility of this system (AutoPBSC, COBE BCT) for standard leukapheresis and for LVL in the pediatric setting. STUDY DESIGN AND METHODS:A p...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40040404.x

    authors: Torrabadella M,Olivé T,Ortega JJ,Massuet L

    更新日期:2000-04-01 00:00:00

  • Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options.

    abstract::Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.12033

    authors: Maegele M

    更新日期:2013-01-01 00:00:00

  • A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells.

    abstract:BACKGROUND:Studies have demonstrated that immunity against platelet (PLT) transfusions is dependent on recipient antigen-presenting cells (APCs) and their ability to produce nitric oxide (NO). To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO(-)) and its ability to affect PLT immunity. S...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01793.x

    authors: Semple JW,Speck ER,Fabron A Jr,Kim RA,Freedman J

    更新日期:2008-09-01 00:00:00

  • Different growth kinetics in blood components and genetic analysis of Lactococcus garvieae isolated from platelet concentrates.

    abstract:BACKGROUND:In 2014, we experienced the first isolation of Lactococcus garvieae from a platelet concentrate (PC). Thereafter, L. garvieae contamination of PCs occurred in two more cases in Japan. It is rare that bacterial contamination with uncommon strains like this species occurs frequently within a short period. Ther...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15836

    authors: Kozakai M,Matsumoto C,Matsumoto M,Takakura A,Matsubayashi K,Satake M

    更新日期:2020-07-01 00:00:00

  • Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions.

    abstract:BACKGROUND:Pulmonary transfusion reactions are important complications of blood transfusion, yet differentiating these clinical syndromes is diagnostically challenging. We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lu...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13021

    authors: Roubinian NH,Looney MR,Kor DJ,Lowell CA,Gajic O,Hubmayr RD,Gropper MA,Koenigsberg M,Wilson GA,Matthay MA,Toy P,Murphy EL,TRALI Study Group.

    更新日期:2015-08-01 00:00:00

  • Red cell alloantibodies in thalassemia major. Results of an Italian cooperative study.

    abstract::Clinical and serological data on 1435 Italian thalassemia major patients were collected during a cooperative study involving 19 centers in 10 regions. The main findings were as follows: 18 percent of the patients were under 6 years of age, 63 percent between 6 and 15, and 19 percent over 15. Forty-one percent had unde...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1985.25285169198.x

    authors: Sirchia G,Zanella A,Parravicini A,Morelati F,Rebulla P,Masera G

    更新日期:1985-03-01 00:00:00

  • Multiple pH measurement during storage may detect bacterially contaminated platelet concentrates.

    abstract:BACKGROUND:Bacterial contamination or platelet (PLT) metabolism can change the pH of stored PLT concentrates (PCs). Measurement of pH for quality control is currently done on a limited basis. An easy noninvasive method was developed to obtain sequential pH measurements over time, without risking contamination and/or co...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02727.x

    authors: Barker LM,Nanassy OZ,Reed MW,Geelhood SJ,Pfalzgraf RD,Cangelosi GA,De Korte D

    更新日期:2010-12-01 00:00:00

  • Translumbar inferior vena cava catheters: safety and efficacy in peripheral blood stem cell transplantation.

    abstract::Most patients who need peripheral blood stem cell transplantation do not have peripheral venous access that would allow apheresis for stem cell collection. Subclavian apheresis catheters have an unacceptably high incidence of thrombosis-related access failure. A technique has been developed for translumbar placement o...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1990.30690333481.x

    authors: Haire WD,Lieberman RP,Lund GB,Wieczorek BM,Armitage JO,Kessinger A

    更新日期:1990-07-01 00:00:00

  • A multicenter evaluation of heterogeneity in cellular therapy processing laboratory procedure times to assess workload capacity.

    abstract:BACKGROUND:Growth in size and complexity of clinical hematopoietic progenitor cell (HPC) transplant programs necessitates parallel increases in cellular therapy laboratory (CTL) workload. Typically individually developed, HPC product processing is labor and time intensive. Variation in procedure type and numbers across...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15899

    authors: Thibodeaux SR,McKenna DH,Szczepiorkowski ZM,Fontaine MJ,Kelley L,Reems JA,Young PP,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

    更新日期:2020-08-01 00:00:00

  • A DEL phenotype attributed to RHD Exon 9 sequence deletion: slipped-strand mispairing and blood group polymorphisms.

    abstract:BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14439

    authors: Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

    更新日期:2018-03-01 00:00:00

  • A new method for monitoring the sterility of blood donation.

    abstract::Sterility of blood products is a cardinal contributor to patient safety. Bacteriologic controls of stable products comply with strict regulations, but legislation imposes only limited constraints in the case of perishable products, such as packed red cells (RBCs) or fresh-frozen plasma (FFP). Therefore, it is essentia...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26386209392.x

    authors: Guéguen M,Durand F,Delamaire D,Beauplet A,Tardivel R,Genetet B,Chalumeau H,Balme MC

    更新日期:1986-05-01 00:00:00

  • The accumulation of mono-2-ethylhexylphthalate (MEHP) during storage of whole blood and plasma.

    abstract::The accumulation of the plasticizer di-2-ethylhexylphthalate (DEHP) in blood and blood components has been of considerable concern for some time. We have followed the accumulation of DEHP and one of its major metabolities, mono-2-ethylhexylphthalate (MEHP) during storage of whole blood, platelet-rich plasma, platelet ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1978.18579036383.x

    authors: Rock G,Secours VE,Franklin CA,Chu I,Villeneuve DC

    更新日期:1978-09-01 00:00:00

  • A study of criteria for blood donor deferral.

    abstract::Donor deferral rates in regional blood centers vary from 5 to 24 per cent, reducing by more than 1,250,000 the number of units of volunteer blood available for transfusion in the nation each year. Those criteria for donor deferral which are intended to exclude donors likely to suffer a "donor reaction" are based parti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1980.20581034503.x

    authors: Tomasulo PA,Anderson AJ,Paluso MB,Gutschenritter MA,Aster RH

    更新日期:1980-09-01 00:00:00

  • Transfusion-related adverse reactions reported to the National Healthcare Safety Network Hemovigilance Module, United States, 2010 to 2012.

    abstract:BACKGROUND:In 2010, health care facilities in the United States began voluntary enrollment in the National Healthcare Safety Network (NHSN) Hemovigilance Module. Participants report transfusion practices; red blood cell, platelet (PLT), plasma, and cryoprecipitate units transfused; and transfusion-related adverse react...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12918

    authors: Harvey AR,Basavaraju SV,Chung KW,Kuehnert MJ

    更新日期:2015-04-01 00:00:00