A new method for monitoring the sterility of blood donation.

abstract：BACKGROUND:In August 2016, the Food and Drug Administration advised US blood centers to screen all whole blood and apheresis donations for Zika virus (ZIKV) with an individual-donor nucleic acid test (ID-NAT) or to use approved pathogen reduction technology (PRT). The cost of implementing this guidance nationally has n...

journal_title：Transfusion

authors： Ellingson KD,Sapiano MRP,Haass KA,Savinkina AA,Baker ML,Henry RA,Berger JJ,Kuehnert MJ,Basavaraju SV

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...

journal_title：Transfusion

authors： Kresnik PK,Krasna M,Rozman P,Vrtovec B,Malicev E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Biological and technical variability has been increasingly appreciated as a key factor impacting red blood cell (RBC) storability and, potentially, transfusion outcomes. Here, we performed metabolomics analyses to investigate the impact of factors other than storage duration on the metabolic phenotypes of st...

journal_title：Transfusion

authors： D'Alessandro A,Culp-Hill R,Reisz JA,Anderson M,Fu X,Nemkov T,Gehrke S,Zheng C,Kanias T,Guo Y,Page G,Gladwin MT,Kleinman S,Lanteri M,Stone M,Busch M,Zimring JC,Recipient Epidemiology and Donor Evaluation Study-III (REDS-

更新日期：2019-01-01 00:00:00

abstract：:The use of citrate-phosphate-dextrose-adenine as an anticoagulant for whole blood increases the storage period permitted for whole blood and red cells from 21 to 35 days. A simulation model was used to analyze the possible consequences for outdates and shortages of the addition of adenine. The model accepts as input (...

journal_title：Transfusion

authors： Cohen MA,Pierskalla WP,Sassetti RJ

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Recruitment of young donors is critical to expand the donor base and sustain the blood supply. Nevertheless, there is concern that younger blood donors may have a higher risk profile than their older counterparts. STUDY DESIGN AND METHODS:The prevalence of behavioral risks associated with transfusion-transm...

journal_title：Transfusion

authors： Damesyn MA,Glynn SA,Schreiber GB,Ownby HE,Bethel J,Fridey J,McMullen Q,Garratty G,Busch MP,NHLBI Retrovirus Epidemiology Donor Study.

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Recent studies conducted in developed countries described hepatitis E virus (HEV) as an emerging infectious threat to blood safety. However, data on HEV among blood donors from southeast Asia are lacking. STUDY DESIGN AND METHODS:Between July and August 2014, we assessed the presence of HEV immunoglobulin (...

journal_title：Transfusion

authors： Nouhin J,Prak S,Madec Y,Barennes H,Weissel R,Hok K,Pavio N,Rouet F

更新日期：2016-10-01 00:00:00

abstract：:After 30 years of hematopoietic stem cell use for various indications, umbilical cord blood is considered as an established source of cells with marrow and postmobilization peripheral blood. The limited number of cells still remains a problematic element restricting their use, especially in adults who require to be gr...

journal_title：Transfusion

authors： Faivre L,Couzin C,Boucher H,Domet T,Desproges A,Sibony O,Bechard M,Vanneaux V,Larghero J,Cras A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Little information exists on the specific transfusion-related acute lung injury (TRALI) risk reduction practices used by multiple blood collecting institutions in the United States. STUDY DESIGN AND METHODS:An AABB-appointed TRALI working group designed a set of questions about TRALI risk reduction for plat...

journal_title：Transfusion

authors： Kleinman S,Grossman B,Kopko P

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The FDA requirement for sensitivity of viral NAT methods used in blood screening is a 95-percent detection limit of 100 copies per mL, whereas the NAT screening system should have a sensitivity of at least 5000 copies per mL per individual donation. According to the Common Technical Specifications of the Eur...

journal_title：Transfusion

authors： Lelie PN,van Drimmelen HA,Cuypers HT,Best SJ,Stramer SL,Hyland C,Allain JP,Moncharmont P,Defer C,Nübling M,Glauser A,da Silva Cardoso M,Viret JF,Lankinen MH,Grillner L,Wirthmüller U,Coste J,Schottstedt V,Masecar B,D

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：:Transfusion practices have changed dramatically in recent years as a result of the acquired immune deficiency syndrome crisis. The use of preoperative donation of autologous blood units has gained popularity. Healthy individuals tolerate phlebotomy well, experiencing a 2- to 5-percent incidence of vasovagal reactions....

journal_title：Transfusion

authors： Spiess BD,Sassetti R,McCarthy RJ,Narbone RF,Tuman KJ,Ivankovich AD

更新日期：1992-01-01 00:00:00

abstract：:The selection of platelet donors, according to HLA antigens, has been computerized using a method based on the calculation of incompatibilities and risk of immunization between donors and recipients. Since the risk that an antigen present in a donor will immunize an incompatible recipient of known HLA phenotype, an in...

journal_title：Transfusion

authors： Muller JY,Cartron JP,Trillot P,Halle L,Roquin H

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Transfusion-transmitted babesiosis (TTB) has been rapidly increasing in incidence since the beginning of the 21st century. Asymptomatic individuals with Babesia infection are able to donate blood in the United States because of the lack of specific blood donation testing. Blood products collected in Babesia-...

journal_title：Transfusion

authors： LeBel DP 2nd,Moritz ED,O'Brien JJ,Lazarchick J,Tormos LM,Duong A,Fontaine MJ,Squires JE,Stramer SL

更新日期：2017-10-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：:The biochemical constituents of a 30-year-old sealed bottle of lyophilized plasma were analyzed. The results in this communication show that the process of lyophilization and storage has not seemed to cause any great changes in plasma components, including hormones, enzymes, and proteins. ...

journal_title：Transfusion

authors： Fu P,Myhre B

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Loss of blood group ABO antigens on red blood cells (RBCs) is well known in patients with leukemias, and such decreased ABO expression has been reported to be strongly associated with hypermethylation of the ABO promoter. We investigated the underlying mechanism responsible for A-antigen reduction on RBCs in...

journal_title：Transfusion

authors： Hayakawa A,Sano R,Takahashi Y,Kubo R,Harada M,Omata M,Yokohama A,Handa H,Tsukada J,Takeshita H,Tsuneyama H,Ogasawara K,Kominato Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Whole blood donors are at risk of becoming iron deficient. To monitor iron stores, Sanquin implemented a new deferral policy based on ferritin levels, in addition to the traditional hemoglobin measurements. METHODS:Ferritin levels are determined in every fifth donation, as well as in all first-time donors. ...

journal_title：Transfusion

authors： Vinkenoog M,van den Hurk K,van Kraaij M,van Leeuwen M,Janssen MP

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

journal_title：Transfusion

authors： Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:A 28-year-old woman of Lebanese origin experienced two stillbirths. At the time, serology typed her red blood cells as being group A D- and found an anti-D in her serum sample. Molecular biology analysis, however, showed that she was in fact RHD+. STUDY DESIGN AND METHODS:To better characterize this case, a...

journal_title：Transfusion

authors： Richard M,Perreault J,Constanzo-Yanez J,Khalifé S,St-Louis M

更新日期：2007-05-01 00:00:00

abstract：:This study evaluated various algorithms for the generation of a red cell antibody identification panel by computer. The algorithms depended on schemes that optimized Fisher's exact p value for each specificity in the panel rather than using predetermined formulations of desired phenotypic combinations. Panels produced...

journal_title：Transfusion

authors： AuBuchon JP,Roberts GC

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Transfusion-associated Chagas' disease (TA-CD) is a worldwide problem. Measures adopted to prevent TA-CD include the clinical and serologic screening of blood donors and/or the inactivation of Trypanosoma cruzi present in collected blood, using gentian violet as the trypanocidal agent. This study investigate...

journal_title：Transfusion

authors： Moraes-Souza H,Bordin JO,Bardossy L,MacPherson DW,Blajchman MA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Phthalocyanines are useful sensitizers for photodynamic sterilization of red cell concentrates. Various lipid-enveloped viruses can be inactivated with only limited red cell damage. Because white cells are involved in the immunomodulatory effects of blood transfusions, the study of the effect of photodynamic...

journal_title：Transfusion

authors： Moor AC,van der Veen A,Dubbelman TM,VanSteveninck J,Brand A

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Erythrocytapheresis (ECP), automated red blood cell exchange, is increasingly being used for chronic transfusion therapy in sickle cell disease (SCD) as it is an isovolumetric transfusion, is more effective in lowering hemoglobin (Hb)S, and can limit iron overload. Because ECP requires increased blood exposu...

journal_title：Transfusion

authors： Wahl SK,Garcia A,Hagar W,Gildengorin G,Quirolo K,Vichinsky E

更新日期：2012-12-01 00:00:00

abstract：:Evidence supporting the existence of two agents of human non-A, non-B hepatitis was obtained by the inoculation of chimpanzees sequentially with serum from a chronically infected human (Inoculum I) and with fibrinogen prepared from pooled plasma (Inoculum IV), each of which had transmitted non-A, non-B hepatitis to hu...

journal_title：Transfusion

authors： Tabor E,Snoy P,Jackson DR,Schaff Z,Blatt PM,Gerety RJ

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Evaluation of hemostasis in bleeding patients requires both accuracy and speed. STUDY DESIGN AND METHODS:As an alternative to point-of-care testing, we developed an emergency hemorrhage panel (EHP: prothrombin time [PT], fibrinogen, platelet count, hematocrit) for use in making transfusion decisions on blee...

journal_title：Transfusion

authors： Chandler WL,Ferrell C,Trimble S,Moody S

更新日期：2010-12-01 00:00:00

abstract：:An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblo...

journal_title：Transfusion

authors： Daniels GL,Okubo Y,Yamaguchi H,Seno T,Ikuta M

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Clinical outcomes in transfused patients may be affected by the duration of blood storage, possibly due to red blood cell (RBC)-mediated disruption of nitric oxide (NO) signaling, a key regulator of vascular tone and blood flow. STUDY DESIGN AND METHODS:AS-1 RBC units stored up to 42 days were sampled at se...

journal_title：Transfusion

authors： Alexander JT,El-Ali AM,Newman JL,Karatela S,Predmore BL,Lefer DJ,Sutliff RL,Roback JD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:To quantify the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) on the risk of HIV transmission through infected blood donations in countries supported by PEPFAR blood safety programs. METHODS:Data reported to the World Health Organization Global Database on Blood Safety were analyzed f...

journal_title：Transfusion

authors： Mili FD,Teng Y,Shiraishi RW,Yu J,Bock N,Drammeh B,Watts DH,Benech I

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:The AABB Clinical Transfusion Medicine Committee (CTMC) compiles an annual synopsis of the published literature covering important developments in the field of transfusion medicine (TM) for the board of director's review. This synopsis is now made available as a manuscript published in TRANSFUSION. STUDY DE...

journal_title：Transfusion

authors： Pagano MB,Allen ES,Chou ST,Dunbar NM,Gniadek T,Goel R,Harm SK,Hopkins CK,Jacobson J,Lokhandwala PM,Metcalf RA,Raval JS,Schwartz J,Shan H,Spinella PC,Storch E,Cohn CS

更新日期：2020-07-01 00:00:00