Red blood cells stored for increasing periods produce progressive impairments in nitric oxide-mediated vasodilation.

abstract：:Erythrocytes stored in the new CPD-adenine anticoagulant (CPDA-1) barely met the 70 per cent 24-hour postinfusion 51Cr recoveries on day 35 when stored at hematocrit greater than or equal to 75 per cent. CPDA-1 differs from CPD in that it has 1.25 times the glucose concentration plus 17.3 mg adenine/63 ml. In an effor...

journal_title：Transfusion

authors： Moore GL,Ledford ME,Peck CC

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the potential yield of introducing nucleic acid amplification testing (NAT) in blood donation, according to the detection threshold and the pool size. STUDY DESIGN AND METHODS:A mathematical model of early HIV-1 population dynamics in blood has been developed and is used ...

journal_title：Transfusion

authors： Le Corfec E,Le Pont F,Tuckwell HC,Rouzioux C,Costagliola D

更新日期：1999-10-01 00:00:00

abstract：:Twenty-five leukaphereses were done by the Haemonetics system using citrated Dextran 75 in normal saline as anticoagulant, and were compared with a much larger series using hydroxyethyl starch (HES) with and without steroid premedication. The granulocyte and platelet yields were only minimally different between the tw...

journal_title：Transfusion

authors： Huestis DW

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:A new automated apheresis system has recently been reported as useful in improving peripheral blood HPC collection in adults. The aim of this study has been to verify the utility of this system (AutoPBSC, COBE BCT) for standard leukapheresis and for LVL in the pediatric setting. STUDY DESIGN AND METHODS:A p...

journal_title：Transfusion

authors： Torrabadella M,Olivé T,Ortega JJ,Massuet L

更新日期：2000-04-01 00:00:00

abstract：:The growth of Yersinia enterocolitica in AS-1 red cells was investigated so as to study the organism's proliferation kinetics and to evaluate the effect of prestorage white cell (WBC) reduction on bacterial multiplication. Twenty-four 2-unit pools of ABO-compatible whole blood were prepared and inoculated with Y. ente...

journal_title：Transfusion

authors： Buchholz DH,AuBuchon JP,Snyder EL,Kandler R,Edberg S,Piscitelli V,Pickard C,Napychank P

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Uncommonly, antibodies that appear to exhibit antigenic specificity on red blood cell (RBC) panels fail to maintain specificity following alloadsorption (i.e., they mimic antigenic specificity). Understanding both the pitfalls and the proper pathways to establish the diagnosis and to interpret the clinical s...

journal_title：Transfusion

authors： Dwyre DM,Clapper A,Heintz M,Elbert C,Strauss RG

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Human herpesvirus 8 (HHV-8) seroprevalence ranges between less than 5% in Europe and North America and 50% to 70% in sub-Saharan Africa. Evidence of HHV-8 transfusion transmission is only indirect. We conducted a serologic (anti-HHV-8) and molecular (HHV-8 DNA) study of samples from paired donor-immunocompet...

journal_title：Transfusion

authors： Gobbini F,Owusu-Ofori S,Marcelin AG,Candotti D,Allain JP

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：:Autologous blood donors (ABDs) have been reported to have favorable attitudes toward returning as homologous blood donors (HBDs), but the frequency of return has not been well documented. ABDs eligible by history to be HBDs were followed at one blood center: 255 donating for elective surgery and 234 donating during pr...

journal_title：Transfusion

authors： McVay PA,Fung HC,Toy PT

更新日期：1991-02-01 00:00:00

abstract：:An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was dest...

journal_title：Transfusion

authors： Issitt PD,Valinsky JE,Marsh WL,DiNapoli J,Gutgsell NS

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies against fetal human platelet antigens (HPAs), mostly caused by anti-HPA-1a. Population-based screening for FNAIT is still a topic of debate. Logistically and financially, the major challenge for implementation is the ...

journal_title：Transfusion

authors： Winkelhorst D,Porcelijn L,Muizelaar E,Oldert G,Huiskes E,van der Schoot CE

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The Mirasol pathogen reduction technology (PRT) system for plasma is based on a riboflavin (vitamin B(2)) and ultraviolet (UV) light treatment process resulting in pathogen inactivation due to irreversible photo-oxidative damage of nucleic acids. The purpose of this study was to evaluate the in vitro protein...

journal_title：Transfusion

authors： Smith J,Rock G

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron stores expressed as fe...

journal_title：Transfusion

authors： Rigas AS,Berkfors AA,Pedersen OB,Sørensen E,Nielsen KR,Larsen MH,Paarup HM,Wandall HH,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2017-12-01 00:00:00

abstract：:Bone marrow was harvested for the purpose of autologous bone marrow transplantation (ABMT) in 21 patients previously treated with chemotherapy and in complete remission from acute leukemia or non-Hodgkin's lymphoma. The volume required to obtain 2 x 10(8) nucleated cells per kg was less than 15 mL per kg in 13 patient...

journal_title：Transfusion

authors： Sonneveld P,de Leeuw CA,Schipperus M,Lindemans J,Abels J

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Transfusion safety rests heavily on the health of blood donors. Although they are perceived as being healthier than average, little is known about their long-term disease patterns and to which extent the blood banks' continuous efforts to optimize donor selection has resulted in improvements. Mortality and c...

journal_title：Transfusion

authors： Edgren G,Tran TN,Hjalgrim H,Rostgaard K,Shanwell A,Titlestad K,Wikman A,Norda R,Jersild C,Wideroff L,Gridley G,Adami J,Melbye M,Nyrén O,Reilly M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Optimal skin disinfection ensures blood safety. In this study, efficacies of the two-step skin disinfection methods used at Canadian Blood Services (CBS) and two one-step methods produced by different manufacturers were compared. STUDY DESIGN AND METHODS:In each of the three phases of the study, two methods...

journal_title：Transfusion

authors： Ramirez-Arcos S,Goldman M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:For patients with thrombocytopenia without bleeding risk factors, a platelet transfusion trigger of 10 × 10(9) /L is recommended. No studies have evaluated the clinicians' decision-making process leading to trigger changes. STUDY DESIGN AND METHODS:We report on the evaluation of trigger changes and the rela...

journal_title：Transfusion

authors： Rioux-Massé B,Laroche V,Bowman RJ,Lindgren BR,Cohn CS,Pulkrabek SM,McCullough J

更新日期：2013-02-01 00:00:00

abstract：:The introduction of plerixafor as a peripheral blood stem cell mobilization agent has allowed more patients with multiple myeloma, non-Hodgkin's lymphoma, and Hodgkin's disease to mobilize sufficient hematopoietic progenitor cells (HPCs) to proceed to autologous transplantation. Because of the high cost of plerixafor,...

journal_title：Transfusion

authors： Tanhehco YC,Vogl DT,Stadtmauer EA,O'Doherty U

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:At most US blood centers, patients may still opt to choose specific donors to give blood for their anticipated transfusion needs. However, there is little evidence of improved safety with directed donation when compared to volunteer donation. STUDY DESIGN AND METHODS:The percentage of directed donations mad...

journal_title：Transfusion

authors： Dorsey KA,Moritz ED,Steele WR,Eder AF,Stramer SL

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:West Nile virus (WNV) infection is mostly asymptomatic (AS) but 20% of subjects report WNV fever and 1% of patients experience neurologic diseases with higher rates in elderly and immunosuppressed persons. With no treatment and no vaccine to prevent the development of symptomatic (S) infections, it is essent...

journal_title：Transfusion

authors： Kaidarova Z,Bravo MD,Kamel HT,Custer BS,Busch MP,Lanteri MC

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) bas...

journal_title：Transfusion

authors： Poiesz BJ,Dube S,Jones B,Bryz-Gornia V,Dean MT,Spicer T,Hengst J,Sayre K,Esteban E,Ferrer JF

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Currently, donors may arrive at blood collection sites without prior knowledge of eligibility and deferral criteria. STUDY DESIGN AND METHODS:The effects of distributing newly developed recruitment brochures 2 weeks in advance of blood drives and the provision of brochures on temporary deferral at the takin...

journal_title：Transfusion

authors： Gimble JG,Kline L,Makris N,Muenz LR,Friedman LI

更新日期：1994-07-01 00:00:00

abstract：:Removal of white cells (WBCs) from platelets may reduce alloimmunization to WBC antigens, prevent febrile reactions, and improve platelet increments in multiply transfused patients receiving HLA-matched platelets. A new surface-modified fibrous polyester filter was evaluated; it requires no special processing of poole...

journal_title：Transfusion

authors： Kickler TS,Bell W,Drew H,Pall D

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Storage age of red blood cells (RBCs) has been reported to be associated with increased mortality and morbidity. During storage, RBCs undergo changes in biochemical and functional properties. Stored RBCs may also contain white blood cells (WBCs), activated platelets (PLTs), cytokines, immunoglobulin, and oth...

journal_title：Transfusion

authors： Sowemimo-Coker SO

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The de novo development of anti-D after D-mismatched allogeneic hematopoietic stem cell transplantation (AHSCT) is a possibility that must be considered. The transfusion of D- blood components after AHSCT has been recommended but anti-D alloimmunization in this setting has been studied little. Thus, the aim ...

journal_title：Transfusion

authors： Cid J,Lozano M,Fernández-Avilés F,Carreras E,Pereira A,Mazzara R,Ordinas A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS:In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and ...

journal_title：Transfusion

authors： Reiher VSA,Hönger G,Infanti L,Passweg JR,Hösli I,Frey BM,Gassner C,Meyer S,Buser AS,Holbro A,Schaub S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:By regulation, ongoing process control of WBC-reduced processes is performed on 1 percent of WBC-reduced components, typically four to five samples per month. However, prospective study of the power of this small sample has been difficult. Using computer-generated "residual WBC" distributions, sample size se...

journal_title：Transfusion

authors： Adams MR,Fisher DM,Dumont LJ,Dzik WH,Heaton WA

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The infusion of citrate during apheresis may affect the levels of ionized magnesium in the blood. Hypomagnesemia and concomitant hypocalcemia could influence the parathormone response and could be responsible for some of the symptoms observed during apheresis. STUDY DESIGN AND METHODS:The study reports meas...

journal_title：Transfusion

authors： Mercan D,Bastin G,Lambermont M,Dupont E

更新日期：1997-04-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00