Computerized selection of donors for inclusion in red cell antibody panels.

Abstract:

:This study evaluated various algorithms for the generation of a red cell antibody identification panel by computer. The algorithms depended on schemes that optimized Fisher's exact p value for each specificity in the panel rather than using predetermined formulations of desired phenotypic combinations. Panels produced by these computer-driven algorithms offered the distinction of a greater number of antibody specificities than manually created panels. They were also evaluated by a group of technologists to be more useful for general serologic work than panels created manually. Although the panels were created from a database of only 252 donors, an objective numeric evaluation showed that the panels were more useful than commercial panels. The computer approach used in this study may offer means of efficiently creating panels for general use as well as creating panels for resolution of particular serologic problems. They may also facilitate and encourage the construction of panels from small donor databases.

journal_name

Transfusion

journal_title

Transfusion

authors

AuBuchon JP,Roberts GC

doi

10.1046/j.1537-2995.1987.27187121480.x

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

69-74

issue

1

eissn

0041-1132

issn

1537-2995

journal_volume

27

pub_type

杂志文章
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    pub_type: 杂志文章

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  • Assessment of cell viability, early apoptosis, and hematopoietic potential in umbilical cord blood units after storage.

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    doi:10.1046/j.1537-2995.1999.39060599.x

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  • Platelet storage in a plasma-free medium.

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  • Effects of blood storage age on immune, coagulation, and nitric oxide parameters in transfused patients undergoing cardiac surgery.

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  • Cytokine generation in stored, white cell-reduced, and bacterially contaminated units of red cells.

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  • Variation in concentration of prion protein in the peripheral blood of patients with variant and sporadic Creutzfeldt-Jakob disease detected by dissociation enhanced lanthanide fluoroimmunoassay and flow cytometry.

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