Donor WBCs can persist and transiently mediate immunologic function in a murine transfusion model: effects of irradiation, storage, and histocompatibility.

abstract：BACKGROUND:The residual blood left in the placenta, previously considered a biologic waste, contains sufficient hematopoietic stem and progenitor cells to consistently engraft at least a small recipient. Over the past several years, more than 500 HLA-matched, related and unrelated, allogeneic cord blood transplants hav...

journal_title：Transfusion

authors： Reems JA,Fujita D,Tyler T,Moldwin R,Smith SD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:To reduce donor iron deficiency in whole blood donors, we changed our hemoglobin (Hb) cutoff in males and interdonation interval in females. STUDY DESIGN AND METHODS:A change in messaging to females in fall 2016 was followed by changing the interdonation interval from 56 to 84 days in the appointment bookin...

journal_title：Transfusion

authors： Goldman M,Yi QL,Steed T,O'Brien SF

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The term platelet storage lesion (PSL) describes the structural and biochemical changes in platelets (PLTs) during storage. These are typified by alterations of morphologic features and PLT metabolism leading to reduced functionality and hence reduced viability for transfusion. While the manifestations of th...

journal_title：Transfusion

authors： Schubert P,Thon JN,Walsh GM,Chen CH,Moore ED,Devine DV,Kast J

更新日期：2009-09-01 00:00:00

abstract：:Prospective-concurrent audits and medical consultation were associated with a 56 percent decrease in the use of platelet concentrates at a tertiary care medical center. This study documents that mandatory pretransfusion review of component requests can alter hospital transfusion practices. ...

journal_title：Transfusion

authors： Simpson MB

更新日期：1987-03-01 00:00:00

abstract：:The ability to store platelets beyond 24 hours requires a functionally closed system. This study tested the ability of a cell separator bowl seal system to resist penetration of microbial contamination under normal running conditions and under extreme environmental stress. Three test organisms, Micrococcus luteus, Ser...

journal_title：Transfusion

authors： Jacobson MS,Kevy SV,Thorne GM,Goldmann DA,Blasetti L,Smith JW,Schaefer H

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Pulmonary transfusion reactions are important complications of blood transfusion, yet differentiating these clinical syndromes is diagnostically challenging. We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lu...

journal_title：Transfusion

authors： Roubinian NH,Looney MR,Kor DJ,Lowell CA,Gajic O,Hubmayr RD,Gropper MA,Koenigsberg M,Wilson GA,Matthay MA,Toy P,Murphy EL,TRALI Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:New alloantibody formation is unpredictable in patients who have been previously alloimmunized. Pretransfusion testing is designed to detect these antibodies while antibody identification (ABI) techniques are designed to identify the specificity of the antibody. Pretransfusion testing intervals are prescribe...

journal_title：Transfusion

authors： Goss C,Avecilla ST,Garbaini J,Degtyaryova D,Lo D,Chang DY,Cushing M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Blood banks ensure the safety of blood components by testing them for a set of known infectious agents and by careful selection of donors based on a self-administered questionnaire and an interview. The purpose of this study is to describe the risk behavior for sexually transmitted diseases in Norwegian bloo...

journal_title：Transfusion

authors： Stigum H,Bosnes V,Ørjasaeter H,Heier HE,Magnus P

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

journal_title：Transfusion

authors： Wallis JP,Lubenko A,Wells AW,Chapman CE

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

journal_title：Transfusion

authors： McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS:Double-dose PLTs (n = 15) were generated using a commercially available aphere...

journal_title：Transfusion

authors： Picker SM,Tauszig ME,Gathof BS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Cord blood (CB) is a widely accepted stem cell source and its clinical utilization depends, to a great extent, on its cell content. Birth-to-clamping (BTC) time of umbilical cord determines placental transfusion to the newborn, and the remaining blood that can be collected and banked. The 2017 Committee Opin...

journal_title：Transfusion

authors： Ciubotariu R,Scaradavou A,Ciubotariu I,Tarnawski M,Lloyd S,Albano M,Dobrila L,Rubinstein P,Grunebaum A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Stored red blood cells (RBCs) undergo progressive deleterious functional, biochemical, and structural changes. The mechanisms responsible for the adverse effects of transfusing stored RBCs remain incompletely elucidated. STUDY DESIGN AND METHODS:Awake wild-type (WT) mice, WT mice fed a high-fat diet (HFD-fe...

journal_title：Transfusion

authors： Yu B,Lei C,Baron DM,Steinbicker AU,Bloch KD,Zapol WM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Effective donor skin disinfection is essential in preventing bacterial contamination of blood components with skin flora bacteria like Staphylococcus epidermidis. Cell aggregates of S. epidermidis (biofilms) are found on the skin and are resistant to the commonly used donor skin disinfectants chlorhexidine-g...

journal_title：Transfusion

authors： Alabdullatif M,Boujezza I,Mekni M,Taha M,Kumaran D,Yi QL,Landoulsi A,Ramirez-Arcos S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Identification of antibodies against high-prevalence Scianna (Sc; ERMAP) antigens, like Sc1 and Sc5, is difficult and may incur delays in blood procurement and costs. The detection of additional clinically significant alloantibodies is hampered in the presence of anti-Scianna. Soluble recombinant Scianna pro...

journal_title：Transfusion

authors： Seltsam A,Grueger D,Blasczyk R,Flegel WA

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Research with primary human white blood cell (WBC) subpopulations requires high quantity, quality, and functionality of peripheral blood mononuclear cells (PBMCs) as a source to further characterize cellular subpopulations such as T and B lymphocytes, monocytes, or natural killer cells. Apart from buffy coat...

journal_title：Transfusion

authors： Knörck A,Marx S,Friedmann KS,Zöphel S,Lieblang L,Hässig C,Müller I,Pilch J,Sester U,Hoth M,Eichler H,Sester M,Schwarz EC

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

journal_title：Transfusion

authors： Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Iron deficiency represents a risk to donor health and the blood supply. Efficacy trials indicate that postdonation iron replacement improves iron stores but they do not account for complexities of implementation in the routine collection context. We therefore conducted two prospective feasibility studies in ...

journal_title：Transfusion

authors： Pasricha SR,Marks DC,Salvin H,Brama T,Keller AJ,Pink J,Speedy J

更新日期：2017-08-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Preliminary evidence of cases of acute occult hepatitis B virus (HBV) infection (OBI) has been recently reported in the literature. Furthermore, OBI definition has been the object of an international consensus conference. STUDY DESIGN AND METHODS:A case of acute primary OBI was identified and followed up in...

journal_title：Transfusion

authors： Manzini P,Abate ML,Valpreda C,Milanesi P,Curti F,Rizzetto M,Smedile A

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is due to maternal alloimmunization against fetal platelet (PLT) antigens. Antenatal management strategies have been developed to avoid complications such as intracranial hemorrhage. The aim of this study was to set up two reliable, noninvasive fetal gen...

journal_title：Transfusion

authors： Le Toriellec E,Chenet C,Kaplan C

更新日期：2013-08-01 00:00:00

abstract：:Interest has been renewed in CPD-adenine as a long-term liquid blood preservative. The question of whether the metabolic product of adenine, 2,8-dioxyadenine was toxic to humans has apparently been resolved by extensive animal and human studies in favor of there being no potential toxicity in the amounts used in blood...

journal_title：Transfusion

authors： Dawson RB,Ellis TJ,Hershey RT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Passive immunotherapy in human immunodeficiency virus (HIV) infection is based on transfusions of plasma that is rich in HIV antibodies. STUDY DESIGN AND METHODS:To verify whether the clearance of transfused antibodies will maintain an elevated titer of specific antibodies between biweekly transfusions of p...

journal_title：Transfusion

authors： Lefrère JJ,Roudot-Thoraval F,Vittecoq D,Heshmati F,Audat F,Lerable J,Reed D,Petit JC,Burghoffer B,Morand-Joubert L

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Data on red blood cell (RBC) transfusion in the United States show variation in practice and overprescribing or overdosing is considered to be prevalent. Education or restrictive interventions could modify practice. STUDY DESIGN AND METHODS:RBC transfusion and mortality rates were recorded in a single insti...

journal_title：Transfusion

authors： Tavares MM,Diquattro PJ,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Epitopes of blood group A antigen can be enzymatically cleaved from red cells (RBCs), but the extent of cleavage required for normal survival in allogeneic blood transfusion recipients is unknown. Therefore, the cleavage rates were studied for A antigen epitope binding of 1) complement-activating anti-A, 2) ...

journal_title：Transfusion

authors： Hoskins LC,Larson G,Naff GB

更新日期：1995-10-01 00:00:00

abstract：:Clinical and serological data on 1435 Italian thalassemia major patients were collected during a cooperative study involving 19 centers in 10 regions. The main findings were as follows: 18 percent of the patients were under 6 years of age, 63 percent between 6 and 15, and 19 percent over 15. Forty-one percent had unde...

journal_title：Transfusion

authors： Sirchia G,Zanella A,Parravicini A,Morelati F,Rebulla P,Masera G

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:A case of donor cell leukemia (DCL) is reported. A 42-year-old female developed acute myeloid leukemia (AML) of donor cell origin 18 months after a bone marrow transplant (BMT) from her brother. At the time DCL presented, the donor-brother was also diagnosed with AML showing identical cytogenetic abnormaliti...

journal_title：Transfusion

authors： Glasser L,Meloni-Ehrig A,Greaves W,Demel KC,Butera J

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Recent studies conducted in developed countries described hepatitis E virus (HEV) as an emerging infectious threat to blood safety. However, data on HEV among blood donors from southeast Asia are lacking. STUDY DESIGN AND METHODS:Between July and August 2014, we assessed the presence of HEV immunoglobulin (...

journal_title：Transfusion

authors： Nouhin J,Prak S,Madec Y,Barennes H,Weissel R,Hok K,Pavio N,Rouet F

更新日期：2016-10-01 00:00:00

abstract：:A 24-year-old, blood-group O Polynesian woman with multiple red blood cell antibodies received a group A, HLA-compatible, sex-matched bone marrow transplantation as treatment for severe aplastic anemia. High retransplantation titers of ABO isohemagglutinins were successfully reduced by repeated plasmaphereses. Despite...

journal_title：Transfusion

authors： Ockelford PA,Hill RS,Nelson L,Blacklock HA,Woodfield DG,Matthews JR

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:In spite of interventions, approximately 1000 per 1,000,000 platelet (PLT) collections are contaminated with bacteria at collection. The current prestorage culture procedure at some blood centers is to inoculate a fixed volume from the collection bag (4-8 mL) regardless of collection volume. The sensitivity ...

journal_title：Transfusion

authors： Tomasulo PA,Wagner SJ

更新日期：2013-04-01 00:00:00