Impact of delayed umbilical cord clamping on public cord blood donations: can we help future patients and benefit infant donors?

abstract：BACKGROUND:To quantify the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) on the risk of HIV transmission through infected blood donations in countries supported by PEPFAR blood safety programs. METHODS:Data reported to the World Health Organization Global Database on Blood Safety were analyzed f...

journal_title：Transfusion

authors： Mili FD,Teng Y,Shiraishi RW,Yu J,Bock N,Drammeh B,Watts DH,Benech I

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Recent blood shortages and the potential clinical impact of red blood cell (RBC) age highlight the need to understand blood supply delivery. This study addresses the characteristics and mechanics of RBC unit trafficking and storage across the transfusion service, previously undescribed in the literature. ST...

journal_title：Transfusion

authors： Cheng CK,Trethewey D,Sadek I

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical treatment (PCT) process with amotosalen-HCl and long-wavelength ultraviolet light (UVA), which cross-links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentra...

journal_title：Transfusion

authors： Lin L,Hanson CV,Alter HJ,Jauvin V,Bernard KA,Murthy KK,Metzel P,Corash L

更新日期：2005-04-01 00:00:00

abstract：:EDTA is added to some commercial A and B cells as a means of preventing hemolysis in serum testing. Unexpected results in serum testing have been reported with EDTA-dependent agglutinins, but not with agglutinins inhibited by EDTA. A serum sample was found to contain an anti-A1 undetected by serum testing, but resulti...

journal_title：Transfusion

authors： Tedrow HE,Zeigler ZR

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

journal_title：Transfusion

authors： Fuller AK,Uglik KM,Braine HG,King KE

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Hematology analyzers use impedance, optical, and/or immunologic techniques for counting platelets (PLTs). PLT counting in whole blood has been validated thoroughly; however, this is not the case for PLT counting in PLT concentrates (PCs), in which red cells (RBCs) are absent. Therefore, this study is focused...

journal_title：Transfusion

authors： Dijkstra-Tiekstra MJ,Kuipers W,Setroikromo AC,de Wildt-Eggen J

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

journal_title：Transfusion

authors： González R,Echevarria JM,Avellón A,Barea L,Castro E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Filtration of apheresis platelets to remove white cells (WBCs) requires operator intervention after the collection procedure (postcollection filtration), which may cause variable and unsatisfactory filter performance (WBC removal and platelet loss). The MCS+ LN9000 apheresis system filters platelets through ...

journal_title：Transfusion

authors： Holme S,Andres M,Goermar N,Giordano GF

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization occurs at a high frequency in sickle cell anemia (SCA) despite serologic matching for Rh (C/c, E/e) and K antigens. RBC minor antigen genotyping allows for prediction of antigens and RH variants that may lead to alloimmunization. STUDY DESIGN AND METHODS:RBC antigen gen...

journal_title：Transfusion

authors： Yee MEM,Josephson CD,Winkler AM,Webb J,Luban NLC,Leong T,Stowell SR,Fasano RM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Serious complications of blood donation are rare. Reported here is a significant vascular event that resulted from whole-blood phlebotomy and required surgical repair. CASE REPORT:A 49-year-old woman donated whole blood without incident in November 1992, but reported ecchymosis and tenderness in the antecub...

journal_title：Transfusion

authors： Popovsky MA,McCarthy S,Hawkins RE

更新日期：1994-03-01 00:00:00

abstract：:Fresh human blood was collected in citrate-phosphate-dextrose, frozen by a high-glycerol technique, and stored at -80 degrees C. The red cells were thawed, deglycerolized, and resuspended in a final wash solution, ADSOL (Fenwal Laboratories), or an additive solution (AS) containing glucose, adenine, mannitol, and phos...

journal_title：Transfusion

authors： Moore GL,Ledford ME,Mathewson PJ,Hankins DJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:The rehydrated, lyophilized (RL) platelet (PLT) is being developed as a hemostatic infusion agent for the control of active bleeding. The key to the method for preparing RL PLTs is a mild aldehyde stabilization that allows for freezing and lyophilizing without cellular rupture. RL PLTs have been shown to be ...

journal_title：Transfusion

authors： Fischer TH,Bode AP,Parker BR,Russell KE,Bender DE,Ramer JK,Read MS

更新日期：2006-11-01 00:00:00

abstract：:Although the high (40 to 50 per cent) glycerol method of freezing red blood cells has many advantages, no feasible procedure for deglycerolizing with only a clinical centrifuge has been available. Thus this method has been restricted to blood centers that distribute a sufficient number of frozen cells to warrant the i...

journal_title：Transfusion

authors： Meryman HT,Hornblower M

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Antibodies to Mia , MUT, and Mur are among the most frequently identified alloantibodies in Southeast Asia. Understanding the characteristics of these antibodies in terms of induction and evanescence would aid in optimizing methods for their detection. STUDY DESIGN AND METHODS:Antibody testing results betwe...

journal_title：Transfusion

authors： Nadarajan VS

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Intraoperative and postoperative red blood cell (RBC) transfusions are relatively frequent events tracked in the American College of Surgeons' National Surgical Quality Improvement Program-Pediatric (ACS-NSQIP-P). This study sought to quantify variation in RBC transfusion practices among hospitals. STUDY DE...

journal_title：Transfusion

authors： Stey AM,Vinocur CD,Moss RL,Hall BL,Cohen ME,Kraemer K,Ko CY,Kenney BD

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The experience of unpleasant blood donation reactions (e.g., dizziness, nausea, and fainting) has been linked to negative attitudes about donation and decreased likelihood of repeat donation. Consequently, interventions to reduce the adverse effects of blood donation are important and likely to increase dono...

journal_title：Transfusion

authors： Hanson SA,France CR

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Prosthetic hip-associated cobalt toxicity (PHACT) is an uncommon, but potentially devastating, complication for patients with metal-on-metal hip implants (MoMs). Clinical management of PHACT is poorly defined, with primary intervention being MoM explant followed by chelation therapy. Therapeutic plasma excha...

journal_title：Transfusion

authors： Grant ML,Karp JK,Palladino M,Le N,Hall N,Herman JH

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:A highly sensitive dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA) and flow cytometry techniques have previously been developed and employed to characterize soluble cellular prion protein (PrP(c)) expression in whole blood and separated components from healthy adult blood donors. No previous stud...

journal_title：Transfusion

authors： Fagge T,Barclay GR,Macgregor I,Head M,Ironside J,Turner M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Human herpesvirus 8 (HHV-8) is a gamma-herpesvirus that causes Kaposi's sarcoma. The prevalence of HHV-8 genomes in US blood donors has not been systemically studied. STUDY DESIGN AND METHODS:A sensitive and quantitative real-time polymerase chain reaction (PCR) assay was used to detect HHV-8 DNA from purif...

journal_title：Transfusion

authors： Qu L,Jenkins F,Triulzi DJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:In February 2007, a 63-year-old man underwent surgery. Retrospective testing with nucleic acid testing (NAT) showed that the patient was human immunodeficiency virus Type 1 (HIV-1) positive 10 days after transfusion. The transfusion-transmitted infection had been identified by a donor-related lookback starte...

journal_title：Transfusion

authors： Schmidt M,Korn K,Nübling CM,Chudy M,Kress J,Horst HA,Geusendam G,Hennig H,Sireis W,Rabenau HF,Doerr HW,Berger A,Hourfar MK,Gubbe K,Karl A,Fickenscher H,Tischer BK,Babiel R,Seifried E,Gürtler L

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Much effort and resources have been devoted to programs that provide transfusion support for patients with sickle cell disease (SCD). The focus of many donor programs is to prevent alloimmunization by recruiting racially matched African American donors to limit the red blood cell (RBC) antigenic differences ...

journal_title：Transfusion

authors： Karafin MS,Field JJ,Gottschall JL,Denomme GA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is reported to occur at an incidence of 5.2% to 23.5% among patients with thalassemia requiring chronic transfusion. With very limited data on alloimmunization among the Chinese population, a territory-wide study has been performed to look at its prevalence among Chinese...

journal_title：Transfusion

authors： Cheng CK,Lee CK,Lin CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Iron supplements reduce the risk of iron depletion in blood donors. Recent initiatives have sought to increase use of donor iron supplementation (IS), but a baseline description of blood donor supplement practices is needed. STUDY DESIGN AND METHODS:Presenting blood donors received a questionnaire inquiring...

journal_title：Transfusion

authors： Cable RG,Spencer BR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

journal_title：Transfusion

authors： Borkent-Raven BA,Janssen MP,Van Der Poel CL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Antibodies specific for the neutrophil antigen HNA-3a cause severe, sometimes fatal transfusion-related acute lung disease (TRALI) when transfused, but it has not been possible to screen blood donors for anti-HNA-3a because using neutrophils as targets was impractical and molecular properties of the antigen ...

journal_title：Transfusion

authors： Curtis BR,Sullivan MJ,Holyst MT,Szabo A,Bougie DW,Aster RH

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Screening blood units for hepatitis C virus (HCV) with nucleic acid testing (NAT) reduces the risk associated with the long "window period" (8-9 weeks) after HCV infection. The feasibility of adding the HCV core antigen assay in pools to the existing anti-HCV individual screening was examined as an alternati...

journal_title：Transfusion

authors： Beer N,Shinar E,Novack L,Safi J,Soliman H,Yaari A,Goldman-Levi R,Yahalom V,Bolotin A,Sarov B

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:A 28-year-old woman of Lebanese origin experienced two stillbirths. At the time, serology typed her red blood cells as being group A D- and found an anti-D in her serum sample. Molecular biology analysis, however, showed that she was in fact RHD+. STUDY DESIGN AND METHODS:To better characterize this case, a...

journal_title：Transfusion

authors： Richard M,Perreault J,Constanzo-Yanez J,Khalifé S,St-Louis M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The use of blood-saving techniques in elective surgery can produce a favorable cost-benefit ratio only when there is a reasonable likelihood that transfusion will be required. To apply a targeted blood-sparing technique in lung cancer surgery, the patient's preoperative characteristics that predict the use o...

journal_title：Transfusion

authors： Cirasino L,Barosi G,Torre M,Crespi S,Colombo P,Belloni PA

更新日期：2000-10-01 00:00:00