Inactivation of viruses in platelet concentrates by photochemical treatment with amotosalen and long-wavelength ultraviolet light.

abstract：BACKGROUND:Hemolytic disease of the fetus and newborn (HDFN) is a severe disease, resulting from maternal red cell (RBC) alloantibodies directed against fetal RBCs. The effect of a first-trimester antibody screening program on the timely detection of HDFN caused by antibodies other than anti-D was evaluated. STUDY DES...

journal_title：Transfusion

authors： Koelewijn JM,Vrijkotte TG,van der Schoot CE,Bonsel GJ,de Haas M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

journal_title：Transfusion

authors： Wallis JP,Lubenko A,Wells AW,Chapman CE

更新日期：2003-08-01 00:00:00

abstract：:EDTA is added to some commercial A and B cells as a means of preventing hemolysis in serum testing. Unexpected results in serum testing have been reported with EDTA-dependent agglutinins, but not with agglutinins inhibited by EDTA. A serum sample was found to contain an anti-A1 undetected by serum testing, but resulti...

journal_title：Transfusion

authors： Tedrow HE,Zeigler ZR

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:DNA testing has enabled the documenting of numerous variants of RHCE alleles, especially in individuals of African origin. The risk for production of clinically significant alloantibodies to Rh antigens of patients carrying variant RHCE alleles has led us to analyze the different RhCE variants investigated b...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Juszczak G,Beolet M,Deram G,Martin-Blanc S,Dubeaux I,Roussel M,Kappler-Gratias S,Gien D,Poupel S,Rouger P,Le Pennec PY

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...

journal_title：Transfusion

authors： Wu CG,Mason B,Jong J,Erdman D,McKernan L,Oakley M,Soucie M,Evatt B,Yu MY

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Thrombocytopenia is a serious side effect following high-dose chemotherapy or whole-body irradiation. For many patients, a hematopoietic stem cell (HSC) transplant is required as part of the treatment or to restore the integrity of the hematopoietic system. In this article, we first review the origin of thro...

journal_title：Transfusion

authors： Pineault N,Boyer L

更新日期：2011-11-01 00:00:00

abstract：:Newly prepared platelet concentrates (PC) and platelet poor plasma (PPP) stored at either room temperature (RT) or 4 C were analyzed for ammonia content initially, and after storage at 24, 48, and 72 hours. These studies demonstrate that ammonia rapidly accumulates in PC stored at RT. This accumulation appears to be t...

journal_title：Transfusion

authors： Ukrainski CT,Goldfinger D,Pomerance JJ,Lee HC,Farber S,Sanchez R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Patients presenting with acute episodes of thrombotic microangiopathies (TMAs) require urgent access to plasma exchange (PEX). OctaplasLG, a solvent/detergent fresh-frozen plasma product that has undergone viral inactivation and prion reduction step, has been used in our institution since 2013, replacing Oct...

journal_title：Transfusion

authors： Vendramin C,McGuckin S,Alwan F,Westwood JP,Thomas M,Scully M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:To prevent donor loss and improve retention, it is important to understand the major deterrents to blood donation and to identify factors that can be effectively addressed by blood centers. STUDY DESIGN AND METHODS:A 30-item self-administered questionnaire was completed in 2003 by 1705 first-time and 2437 r...

journal_title：Transfusion

authors： Schreiber GB,Schlumpf KS,Glynn SA,Wright DJ,Tu Y,King MR,Higgins MJ,Kessler D,Gilcher R,Nass CC,Guiltinan AM,National Heart, Lung, Blood Institute Retrovirus Epidemiology Donor Study.

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

journal_title：Transfusion

authors： McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Plerixafor is a recently Food and Drug Administration (FDA)-approved CXCR4 antagonist, which is combined with granulocyte-colony-stimulating factor (G-CSF) to facilitate stem cell mobilization of lymphoma and myeloma patients. STUDY DESIGN AND METHODS:To evaluate the effectiveness and the related costs of a...

journal_title：Transfusion

authors： Li J,Hamilton E,Vaughn L,Graiser M,Renfroe H,Lechowicz MJ,Langston A,Prichard JM,Anderson D,Gleason C,Lonial S,Flowers CR,Kaufman JL,Waller EK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...

journal_title：Transfusion

authors： Wang B,Schreiber GB,Glynn SA,Nass CC,Smith JW,Higgins MJ,Hutching ST,Wright DJ,McEntire RL,Murphy EL,Retrovirus Epidemiology Donor Study.

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Selection of CD34+ PBPCs has been applied as a method of reducing graft contamination from neoplastic cells. This procedure seems to delay lymphocyte recovery, while myeloid engraftment is no different from that with unselected PBPC transplants. STUDY DESIGN AND METHODS:Lymphocyte recovery was studied in tw...

journal_title：Transfusion

authors： Laurenti L,Sorà F,Piccirillo N,Chiusolo P,Cicconi S,Rutella S,Serafini R,Garzia MG,Leone G,Sica S

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Platelet-derived biologic response modifiers (BRMs) including RANTES and transforming growth factor (TGF)-beta1 accumulate in platelet components during storage because of platelet activation, and they may play a causative role in nonhemolytic febrile transfusion reactions. The majority of PCs with high unit...

journal_title：Transfusion

authors： Fujihara M,Ikebuchi K,Wakamoto S,Sekiguchi S

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Although the subject of many previous studies, the importance of white blood cell (WBC) alloimmunization in granulocyte transfusion therapy has not been settled. In this study, we report the results of the effects of WBC antibodies in the RING (Resolving Infection in Neutropenia with Granulocytes) study, a r...

journal_title：Transfusion

authors： Price TH,McCullough J,Strauss RG,Ness PM,Hamza TH,Harrison RW,Assmann SF

更新日期：2018-05-01 00:00:00

abstract：:Using a recently developed enzyme-linked immunosorbent assay, gene dosage effects were demonstrated for the Duffy, Ss, and Rh red blood cell antigen systems. We report a comparison by an antibody-binding assay of the relative amounts of Fya and Fyb antigens on FyaFya, FyaFyb, FybFyb, FyaFyx, and FyxFyx erthrocytes, an...

journal_title：Transfusion

authors： Caren LD,Bellavance R,Grumet FC

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Some countries impose an upper age limit on whole blood and double RBC donation while others do not. We evaluated the safety of blood donation in older individuals (≥71 years), and their contribution to the blood supply of five countries. STUDY DESIGN AND METHODS:Twelve blood center members of the Biomedica...

journal_title：Transfusion

authors： Goldman M,Germain M,Grégoire Y,Vassallo RR,Kamel H,Bravo M,Irving DO,Di Angelantonio E,Steele WR,O'Brien SF,Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators.

更新日期：2019-04-01 00:00:00

abstract：:Currently, platelet concentrates are stored in 50 to 60 ml of plasma. A major drawback to storage in plasma is the considerable loss of platelet function which occurs during storage. A modified Tyrodes medium has been developed for storage of platelets. A comparison between platelet concentrates stored in this medium ...

journal_title：Transfusion

authors： Rock G,Swenson SD,Adams GA

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Safe, accurate methods permitting simultaneous and/or repeated measurement of red blood cell (RBC) survival (RCS) are important to investigate pathophysiology and therapy of anemia. Methods using chromium 51 ((51) Cr)-labeled RBCs are unacceptable for infants, children, and pregnant women. We report RCS meas...

journal_title：Transfusion

authors： Mock DM,Matthews NI,Zhu S,Strauss RG,Schmidt RL,Nalbant D,Cress GA,Widness JA

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Partial Rh antigens have been widely described in black individuals. Carriers are prone to immunization when exposed to the normal antigens. In sickle cell disease (SCD), patient alloimmunization is a major cause of transfusion failure. The potential of individuals with partial C antigen to make anti-C has n...

journal_title：Transfusion

authors： Tournamille C,Meunier-Costes N,Costes B,Martret J,Barrault A,Gauthier P,Galactéros F,Nzouékou R,Bierling P,Noizat-Pirenne F

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Information on the probability of survival of transfused patients is needed for policy making, but there is a paucity of empirical research into this question. A Swedish population-based study reported that the 40-month posttransfusion probability of survival was 51 percent in all patients and 41 percent in ...

journal_title：Transfusion

authors： Vamvakas EC,Goldstein R

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

journal_title：Transfusion

authors： Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Travelers returning to the United States from malaria-endemic areas are at increased risk of a potentially fatal infection from Plasmodium falciparum, which requires prompt and aggressive treatment. STUDY DESIGN AND METHODS:Described is a case of a 7-year-old boy who was infected by P. falciparum while in A...

journal_title：Transfusion

authors： Shelat SG,Lott JP,Braga MS

更新日期：2010-04-01 00:00:00

abstract：:We report a case of "naturally-occurring" (nonred blood cell stimulated) anti-K1. The patient had never received a blood transfusion. Red blood cell antibody screening panels showed agglutination with K:1 red blood cells at room temperature and not in the anti-globulin test. Testing with 2-mercaptoethanol showed the a...

journal_title：Transfusion

authors： Kanel GC,Davis I,Bowman JE

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Transfusion-associated microchimerism (TA-MC), the persistence of significant levels of donor white blood cells (WBCs) in blood recipients for prolonged periods, has been demonstrated after nonleukoreduced and leukoreduced transfusion to patients with severe traumatic injury. Development of TA-MC has not bee...

journal_title：Transfusion

authors： Sanchez R,Lee TH,Wen L,Montalvo L,Schechterly C,Colvin C,Alter HJ,Luban NL,Busch MP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:A quality monitoring program (QMP) for platelet concentrates (PCs) was implemented at Canadian Blood Services (CBS) to improve standards and to better understand platelet (PLT) products by supplementing routine quality control (QC). STUDY DESIGN AND METHODS:Annual surveys of PCs from CBS production sites we...

journal_title：Transfusion

authors： Levin E,Jenkins C,Culibrk B,Gyöngyössy-Issa MI,Serrano K,Devine DV

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Advances in the past two decades in dendritic cell (DC) biology paved the way to exploit them as a promising tool in cancer immunotherapy. The prerequisite for DC vaccine preparations is large-scale in vitro generations of homogeneous, mature, and functional DCs. Frequent improvements are being made in the e...

journal_title：Transfusion

authors： Balan S,Kale VP,Limaye LS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

journal_title：Transfusion

authors： Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

更新日期：2004-08-01 00:00:00