Demonstration of gene dosage effects on antigens in the Duffy, Ss, and Rh systems using an enzyme-linked immunosorbent assay.

abstract：BACKGROUND:Tests for platelet-specific antibodies are important in the diagnosis of immune platelet disorders. Monoclonal antibody glycoprotein capture assays have been the gold standards in platelet antibody detection for almost 30 years. However, such assays are complex and cumbersome to perform, which limits their r...

journal_title：Transfusion

authors： Metzner K,Bauer J,Ponzi H,Ujcich A,Curtis BR

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:By consensus definition, the red blood cells (RBCs) of patients that react weak to 2+ in the serologic D test are classified as having the serologic weak D phenotype (weak D). The risk of D alloimmunization in patients with weak D is not well studied. This study retrospectively determined the incidence of D ...

journal_title：Transfusion

authors： Yazer MH,Brunker PA,Bakdash S,Tobian AA,Triulzi DJ,Earnest V,Harris S,Delaney M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Hemolytic transfusion reactions are a rare, yet serious complication of red blood cell (RBC) transfusion. Patients with sickle cell disease (SCD) are at an increased risk for such reactions, because they are prone to make alloantibodies against transfused RBCs, complicating this integral part of their diseas...

journal_title：Transfusion

authors： Dean CL,Maier CL,Roback JD,Stowell SR

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The serological safety of transfusing ≤4 units of low titer group O whole blood (LTOWB) in civilian trauma patients has been demonstrated. This study investigated clinical outcomes of LTOWB recipients compared to patients who received only conventional blood components during their resuscitation. STUDY DESI...

journal_title：Transfusion

authors： Seheult JN,Anto V,Alarcon LH,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:This randomized controlled study was undertaken to determine the effect of recombinant human erythropoietin (rHuEPO) on erythropoiesis, autologous blood collection, and allogeneic transfusion risk in elective surgery patients with low baseline hematocrits. STUDY DESIGN AND METHODS:Patients (n = 204) with lo...

journal_title：Transfusion

authors： Price TH,Goodnough LT,Vogler WR,Sacher RA,Hellman RM,Johnston MF,Bolgiano DC,Abels RI

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Research with primary human white blood cell (WBC) subpopulations requires high quantity, quality, and functionality of peripheral blood mononuclear cells (PBMCs) as a source to further characterize cellular subpopulations such as T and B lymphocytes, monocytes, or natural killer cells. Apart from buffy coat...

journal_title：Transfusion

authors： Knörck A,Marx S,Friedmann KS,Zöphel S,Lieblang L,Hässig C,Müller I,Pilch J,Sester U,Hoth M,Eichler H,Sester M,Schwarz EC

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:In a previous study of 66 human immunodeficiency virus (HIV)-infected US blood donors from 1999 to 2005, HIV-1 non-B and antiretroviral drug-resistant strains accounted for 4.7 and 6.5% of HIV infections, respectively. This study was expanded to include an additional 11 recently acquired infections and 197 e...

journal_title：Transfusion

authors： Brennan CA,Yamaguchi J,Devare SG,Foster GA,Stramer SL

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Currently, donors may arrive at blood collection sites without prior knowledge of eligibility and deferral criteria. STUDY DESIGN AND METHODS:The effects of distributing newly developed recruitment brochures 2 weeks in advance of blood drives and the provision of brochures on temporary deferral at the takin...

journal_title：Transfusion

authors： Gimble JG,Kline L,Makris N,Muenz LR,Friedman LI

更新日期：1994-07-01 00:00:00

abstract：:Each of 20 donors underwent plateletapheresis on both the CS-3000 (Fenwal) and the 2997 (IBM) blood cell separators. The same operator performed both procedures and conducted all product studies for each donor. Platelet collection efficiency was significantly greater with the 2997 (81%) than the CS-3000 (60%) (p less ...

journal_title：Transfusion

authors： Mintz PD

更新日期：1985-07-01 00:00:00

abstract：:This article introduces a new method of component preparation that is capable of producing white cell (WBC)-reduced platelet concentrates (PCs) from whole blood. Whole blood is separated into packed red cells (RBCs) and platelet-rich plasma (PRP) by centrifugation, and the PRP is expressed through a newly designed WBC...

journal_title：Transfusion

authors： Dzik WH,Cusack WF,Gacek MJ

更新日期：1991-07-01 00:00:00

abstract：:A polyolefin plastic (PL 732) bag formulated without liquid plasticizer allows storage of platelets for 5 and, now, up to 7 days. In order to assess the leaching of compounds from this new plastic, extracts of the supernatant from platelet concentrates stored in these bags were analyzed by high-performance liquid chro...

journal_title：Transfusion

authors： Labow RS,Tocchi M,Rock G

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Absolute counts of CD4+ T-lymphocytes are used in the management of patients with human immunodeficiency virus infection. Low absolute counts of CD3+CD4+ cells have also been observed in healthy people--a phenomenon called idiopathic CD4 lymphocytopenia. It is common practice for normal ranges for lymphocyte...

journal_title：Transfusion

authors： Bryant JA,Wylie BR,Yuan FF,Ribeiro A,Thomson AR,Cooley MA,Fletcher A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The overall number of red blood cell (RBC) units distributed to hospitals throughout the world and in the United States has decreased lately. This study was performed to determine if the number of antigen-negative RBC units distributed to hospitals has followed this trend. STUDY DESIGN AND METHODS:Stratifie...

journal_title：Transfusion

authors： Yazer MH,Anani WQ,Denomme GA,Karafin MS,Sayers M,Shaz BH,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The impact of the spread of chikungunya virus (CHIKV) by autochthonous transmission and blood transfusion in nonendemic areas via travelers returning from CHIKV-affected locations is a concern. METHODS:We analyzed the risks of potential CHIKV importation and transfusion transmission from Thailand to Europe ...

journal_title：Transfusion

authors： Appassakij H,Khuntikij P,Silpapojakul K,Promwong C,Rujirojindakul P,Suddeaugrai O,Chullasara A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Haploidentical hematopoietic stem cell transplantation (HSCT) has been increasingly applied in high-risk hematologic patients due to the absence of HLA-matched donors. The aim of this study was to investigate the efficacy and safety of unmanipulated haploidentical allogeneic peripheral blood stem cells trans...

journal_title：Transfusion

authors： Huang W,Li H,Gao C,Bo J,Wang Q,Zhao Y,Jing Y,Wang S,Zhu H,Dou L,Wang L,Yu L

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to explore the molecular basis of the p phenotype by analysis of the recently cloned 4-alpha-galactosyltransferase gene responsible for synthesis of Pk (Gb3) antigen. STUDY DESIGN AND METHODS:Forty samples from individuals of eight different nationalities were investigated by s...

journal_title：Transfusion

authors： Hellberg A,Steffensen R,Yahalom V,Sojka BN,Heier HE,Levene C,Poole J,Olsson ML

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

journal_title：Transfusion

authors： Valeri CR,Lane JP,Srey R,Ragno G

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:New alloantibody formation is unpredictable in patients who have been previously alloimmunized. Pretransfusion testing is designed to detect these antibodies while antibody identification (ABI) techniques are designed to identify the specificity of the antibody. Pretransfusion testing intervals are prescribe...

journal_title：Transfusion

authors： Goss C,Avecilla ST,Garbaini J,Degtyaryova D,Lo D,Chang DY,Cushing M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Platelet transfusion-associated sepsis is usually due to donor skin flora introduced into the unit during phlebotomy. An unusual case of a platelet component contaminated with methicillin-resistant Staphylococcus aureus (MRSA) is reported. CASE REPORT:A 54-year-old man, terminally ill with progressive non-H...

journal_title：Transfusion

authors： Sapatnekar S,Wood EM,Miller JP,Jacobs MR,Arduino MJ,McAllister SK,Kellum ME,Roth V,Yomtovian R

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:There is growing interest in radio frequency identification (RFID) technology application for tracking blood products to achieve higher productivity and safety in the transfusion medicine supply chain. We have conducted a limited study to assess the temperature and biological effects of 13.56 MHz RF radiatio...

journal_title：Transfusion

authors： Davis R,Gottschall J,Gutierrez A,Hohberger C,Veeramani D,Holcombe J

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

journal_title：Transfusion

authors： Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In the Rh blood group system, variant RhD and RhCE express several partial antigens. We investigated RH in samples with partial DIVa that demonstrated weak and variable reactivity with anti-C. STUDY DESIGN AND METHODS:Standard hemagglutination techniques, polymerase chain reaction-based assays, and RH seque...

journal_title：Transfusion

authors： Westhoff CM,Vege S,Halter Hipsky C,Hue-Roye K,Copeland T,Velliquette RW,Horn T,Lomas-Francis C,Reid ME

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:All studied photosensitizers for virus inactivation impair RBCs. To reduce damage to the RBCs without affecting virucidal activity, selective protection of the RBCs is necessary. The ability of the band 3 ligand, dipyridamole, to react with singlet oxygen and to increase the selectivity of photosterilization...

journal_title：Transfusion

authors： vanSteveninck J,Trannoy LL,Besselink GA,Dubbelman TM,Brand A,de Korte D,Verhoeven AJ,Lagerberg JW

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:A storage period of 42 days has been approved by the FDA for RBCs stored in NUTRICEL (AS-3). This study was undertaken to provide data to the FDA about the feasibility of salvaging AS-3 RBCs at the end of their storage period by rejuvenation and freezing, and to evaluate the effect of rejuvenation on indicat...

journal_title：Transfusion

authors： Lockwood WB,Hudgens RW,Szymanski IO,Teno RA,Gray AD

更新日期：2003-11-01 00:00:00

abstract：:The platelets used in this study were collected by serial centrifugation, and within four hours of collection were frozen with 5% dimethylsulfoxide (DMSO) at an overall rate of 2 to 3 C per minute by storage in a mechanical refrigerator at -80 C. The frozen platelets were stored for four to ten weeks before thawing an...

journal_title：Transfusion

authors： Zaroulis CG,Spector JI,Emerson CP,Valeri CR

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:The Verax PGD rapid test for bacteria in platelets (PLTs) has been updated to simplify workflow and improve specificity and sensitivity by employing a novel sequential format. The performance of this updated version, called PGDprime, was evaluated to determine its suitability for use as an FDA-cleared "safet...

journal_title：Transfusion

authors： Vallejo RP,Shinefeld L,LaVerda D,Best N,Lawrence G,Lousararian A,Hornbaker N,Rasmusson P,Mintz PD

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Exposure to blood products during pregnancy carries a potential risk of transfusion transmission of infectious agents. Blood agencies have historically sought optimal deferral and testing strategies to protect blood supplies in part to ensure the protection of pregnant women and their unborn infants. The Zik...

journal_title：Transfusion

authors： Murphy MS,Shehata N,Colas JA,Chassé M,Fergusson DA,O'Brien SF,Goldman M,Tinmouth A,Forster AJ,Wilson K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Five cases of human immunodeficiency virus Type 1 (HIV-1) RNA-positive blood donations are described that escaped detection by three different CE-marked nucleic acid amplification technique (NAT) screening assays. These events were associated with two HIV-1 transmissions to recipients of blood components. Th...

journal_title：Transfusion

authors： Chudy M,Weber-Schehl M,Pichl L,Jork C,Kress J,Heiden M,Funk MB,Nübling CM

更新日期：2012-02-01 00:00:00

abstract：:A simple method for preparing relatively pure C3c fragment from serum-reacted zymosan is described. Although hyperimmunization studies indicate contamination of the "C3c" product by C3d and immunoglobulin antigenic materials, these are present in such small amounts that they do not impair the effectiveness of the prod...

journal_title：Transfusion

authors： Chaplin H Jr,Hoffmann NL,Monroe MC

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:To meet European guidelines for plasma for fractionation, plasma fractionators have implemented parvovirus B19 (B19V) and hepatitis A virus (HAV) nucleic acid test (NAT) screening on test pools. In this study we evaluate recently developed in-house NAT assays for B19V DNA and HAV RNA. The B19V NAT was design...

journal_title：Transfusion

authors： Molenaar-de Backer MW,de Waal M,Sjerps MC,Koppelman MH

更新日期：2016-02-01 00:00:00