Selective protection of RBCs against photodynamic damage by the band 3 ligand dipyridamole.

abstract：:In spite of growing awareness of the potential risks associated with transfusion, the number of platelet units transfused in the United States continues to increase each year. There is a growing interest in ensuring that all transfusions are administered for appropriate reasons. Prospective review of requests for tran...

journal_title：Transfusion

authors： Sielaff BH,Scott EP,Connelly DP

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The absence of hybrid Rhesus boxes denotes an RHD homozygous status and helps to detect the presence of Dce haplotypes instead of dce. RHCE exon 1 C48, characteristic of RHC alleles, and RHCE exon 5 G733, responsible for VS antigenicity, have been noted in many RHce alleles but it was not clearly established...

journal_title：Transfusion

authors： Cotorruelo CM,Munini GM,García Borrás SE,Racca LL,Biondi CS,Racca AL

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Extreme leukocytosis, generally defined as a white blood cell (WBC) count of more than 100 × 10(9) /L consisting largely of blast cells, especially when accompanied by clinical signs and symptoms of leukostasis or hyperviscosity, often predicts a poor clinical outcome in patients with acute leukemia. In this...

journal_title：Transfusion

authors： Kurnaz F,Sivgin S,Pala C,Yildirim R,Baldane S,Kaynar L,Solmaz M,Ozturk A,Eser B,Cetin M,Unal A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Our study characterizes blood use in the ambulatory setting by US elderly Medicare beneficiaries during 2001. As the US population ages and delivery of health care in outpatient settings is on the rise, ambulatory blood utilization is expected to increase. There is currently a lack of broad population-based ...

journal_title：Transfusion

authors： Menis M,Burwen DR,Holness L,Anderson SA

更新日期：2009-06-01 00:00:00

abstract：:The research process is a balance between the inherent risks of new discoveries and the risks of research participant safety. Conflicts of interest, inherent to the research process, as well as those introduced by emerging cellular therapies, have the potential to compromise safety. The relationship of trust between t...

journal_title：Transfusion

authors： Yim R

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:A system has been developed to inactivate a wide spectrum of blood-borne pathogens in red blood cells (RBCs) before transfusion. The system utilizes S-303 to target nucleic acids of pathogens and white blood cells. The safety of pathogen inactivated RBC was assessed using S-303-treated RBCs (S-303 RBCs) and ...

journal_title：Transfusion

authors： North A,Ciaravino V,Mufti N,Corash L

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Platelets contain several mediators, belonging to a family of proinflammatory cytokines named chemokines, that are stored in the organelles. Release and accumulation of these chemokines during storage of platelet concentrates (PCs) might be responsible for nonhemolytic transfusion reactions. STUDY DESIGN AN...

journal_title：Transfusion

authors： Bubel S,Wilhelm D,Entelmann M,Kirchner H,Klüter H

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Thrombotic microangiopathies (TMA) are systemic vasoocclusive disorders associated with significant morbidity and mortality. Rapid and reliable diagnosis of TMA is critical. The diagnosis is complicated by a lack of objective and sensitive laboratory testing as well as multiple concurrent diseases, including...

journal_title：Transfusion

authors： Dwyre DM,Bell AM,Siechen K,Sethi S,Raife TJ

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Historically, paid blood donors were found to transmit hepatitis at higher rates than volunteers. In those older studies, paid donors frequently were recruited from prisons or slum areas--a finding consistent with the belief that monetary payment in itself did not necessarily lead to the high-risk status of ...

journal_title：Transfusion

authors： Strauss RG,Ludwig GA,Smith MV,Villhauer PJ,Randels MJ,Smith-Floss A,Koerner TA

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Mild cases of hemolytic disease of the newborn were being studied when it was recognized that the propositi's red cells carried a novel antigen. STUDY DESIGN AND METHODS:Serologic and genetic studies of a new low-incidence antigen, LOCR (International Society of Blood Transfusion series number 700.53), were...

journal_title：Transfusion

authors： Coghlan G,McCreary J,Underwood V,Zelinski T

更新日期：1994-06-01 00:00:00

abstract：:In the procedure for quality control of red cell concentrates, made white cell (WBC)-poor by filtration, the particle-counting technique was found to be insufficiently sensitive in detecting the remaining WBCs and platelets. Therefore, direct radioimmunoassays were developed using murine monoclonal antibodies specific...

journal_title：Transfusion

authors： Webster MR,Prins HK,Huisman JG

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality. In the past decade blood banks have implemented low-risk TRALI donor strategies, including a male-only donor policy for plasma-containing blood products to prevent onset of TRALI. We performed a meta-analysis...

journal_title：Transfusion

authors： Müller MC,van Stein D,Binnekade JM,van Rhenen DJ,Vlaar AP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The Spectra Optia (SPO; CaridianBCT) is a new apheresis device based on the COBE Spectra (CSP; CaridianBCT) platform. This study was designed to evaluate the safety and efficiency of the SPO in comparison to the predicate CSP device. STUDY DESIGN AND METHODS:Twenty patients were recruited for a randomized, ...

journal_title：Transfusion

authors： Tormey CA,Peddinghaus ME,Erickson M,King KE,Cushing MM,Bill J,Goodrich T,Snyder EL

更新日期：2010-02-01 00:00:00

abstract：:This review considers the various methods currently in use, or under investigation, for the storage of platelets intended for use in the treatment of active hemorrhage. The current standard practice of storing platelets at room temperature (RT) (20°C-24°C) optimizes circulating time, but at the expense of hemostatic f...

journal_title：Transfusion

authors： Milford EM,Reade MC

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) bas...

journal_title：Transfusion

authors： Poiesz BJ,Dube S,Jones B,Bryz-Gornia V,Dean MT,Spicer T,Hengst J,Sayre K,Esteban E,Ferrer JF

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Using the 5'-rapid amplification of cDNA ends technique with the ex vivo culture of AC133-CD34+ cells, a transcription start site was recently identified approximately 0.7 kb upstream from the transcription start sites previously determined. The transcripts from the alternative starting exon 1a were demonstr...

journal_title：Transfusion

authors： Hata Y,Kominato Y,Takizawa H,Tabata S,Michino J,Nishino K,Yasumura S,Yamamoto F

更新日期：2003-05-01 00:00:00

abstract：:A fluorometric assay is described for the detection of red blood cell antibodies. The assay reveals as little as 600 molecules of bound, fluoresceinated rabbit anti-human IgG antibodies per erythrocyte. Eleven patients with possible autoimmune erythrocyte disorder and negative direct antiglobulin test were studied by ...

journal_title：Transfusion

authors： Schreiber AB,Lambermont M,Strosberg AD,Wybran J

更新日期：1981-03-01 00:00:00

abstract：:Current criteria for a reactive (positive) interpretation on hepatitis C virus (HCV) recombinant immunoblot assay (RIBA) require > or = 1+ reactivity to at least two of the four HCV antigens present in the assay. Given that 5-1-1 is a subcomponent of c100-3, there is concern that donor samples reacting only with these...

journal_title：Transfusion

authors： Busch MP,Tobler L,Quan S,Wilber JC,Johnson P,Polito A,Steane E,Zola A,Bahl C,Nelles M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:This study evaluated the effect of routine, uncontrolled, Israeli field storage conditions on the stability and efficacy of Lyo-Plas N freeze-dried plasma (FDP). We evaluated clotting factors V, VIII, and XI; proteins S and C; fibrinogen; partial thromboplastin time (PTT); antithrombin III (ATIII); von Wille...

journal_title：Transfusion

authors： Zur M,Glassberg E,Gorenbein P,Epstein E,Eisenkraft A,Misgav M,Avramovich E

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The relationship between length of storage of red blood cell (RBC) units and biochemical changes has been well studied, but little is known about the progression of cellular immunomodulative properties in blood recipients. This study aims to quantify in vitro T-cell activation and cytokine release by white b...

journal_title：Transfusion

authors： Karam O,Tucci M,Toledano BJ,Robitaille N,Cousineau J,Thibault L,Lacroix J,Le Deist F

更新日期：2009-11-01 00:00:00

abstract：:As an adjunct to antibiotic therapy, granulocytes for infusion often are required within hours of the diagnosis of neonatal sepsis. The logistics of obtaining granulocytes by leukapheresis were evaluated in order to provide, at short notice, a low volume, highly concentrated product. An average of 4.0 X 10(9) granuloc...

journal_title：Transfusion

authors： Kalmin ND,Liles BA

更新日期：1984-05-01 00:00:00

abstract：:A study was made of the metabolism by the rabbit of adenine administered intravenously at a dose of 35 mg/kg with 100 micronCi of 8-14C-adenine. The infused adenine was removed from the blood in two phases, first by diffusion into the tissues and second by metabolic reactions throughout the body. The adenine equilibra...

journal_title：Transfusion

authors： Bartlett GR

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:The FDA requirement for sensitivity of viral NAT methods used in blood screening is a 95-percent detection limit of 100 copies per mL, whereas the NAT screening system should have a sensitivity of at least 5000 copies per mL per individual donation. According to the Common Technical Specifications of the Eur...

journal_title：Transfusion

authors： Lelie PN,van Drimmelen HA,Cuypers HT,Best SJ,Stramer SL,Hyland C,Allain JP,Moncharmont P,Defer C,Nübling M,Glauser A,da Silva Cardoso M,Viret JF,Lankinen MH,Grillner L,Wirthmüller U,Coste J,Schottstedt V,Masecar B,D

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The experience of unpleasant blood donation reactions (e.g., dizziness, nausea, and fainting) has been linked to negative attitudes about donation and decreased likelihood of repeat donation. Consequently, interventions to reduce the adverse effects of blood donation are important and likely to increase dono...

journal_title：Transfusion

authors： Hanson SA,France CR

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Transfusion reactions to platelet concentrates prepared from buffy coats (BC-PCs) were reviewed to determine the effect of some variables of BC-PC preparation and storage: time of BC storage before BC-PC preparation (1-2 days); time of BC-PC storage before transfusion (1-5 days); no white cell reduction vers...

journal_title：Transfusion

authors： Riccardi D,Raspollini E,Rebulla P,Pappalettera M,Marangoni F,Greppi N,Sirchia G

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Understanding factors that impact tissue oxygen extraction may guide red blood cell (RBC) transfusion decision making in preterm infants. Our objective was to assess the influence of enteral feeding and anemia on cerebral and mesenteric oxygen saturation (Csat and Msat) and fractional tissue oxygen extractio...

journal_title：Transfusion

authors： Goldstein GP,Rao A,Ling AY,Ding VY,Chang IJ,Chock VY

更新日期：2020-03-01 00:00:00

abstract：:The ability to store platelets beyond 24 hours requires a functionally closed system. This study tested the ability of a cell separator bowl seal system to resist penetration of microbial contamination under normal running conditions and under extreme environmental stress. Three test organisms, Micrococcus luteus, Ser...

journal_title：Transfusion

authors： Jacobson MS,Kevy SV,Thorne GM,Goldmann DA,Blasetti L,Smith JW,Schaefer H

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Senescent RBCs bear IgG and C3 opsonins that are three to four times less than required for similar phagocytosis of experimentally opsonized RBCs. STUDY DESIGN AND METHODS:Studies were performed to determine the phagocyte receptors involved in phagocytosis in vitro. The effect of clustering of opsonins and ...

journal_title：Transfusion

authors： Tartakover-Matalon S,Shoham-Kessary H,Foltyn V,Gershon H

更新日期：2000-12-01 00:00:00