Preparation of granulocyte concentrates for neonatal patient transfusion.

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Much effort and resources have been devoted to programs that provide transfusion support for patients with sickle cell disease (SCD). The focus of many donor programs is to prevent alloimmunization by recruiting racially matched African American donors to limit the red blood cell (RBC) antigenic differences ...

journal_title：Transfusion

authors： Karafin MS,Field JJ,Gottschall JL,Denomme GA

更新日期：2015-06-01 00:00:00

abstract：:Severe acute hemolytic anemia developed in a woman following treatment with multiple antibiotics for possible postpartum uterine infection. On admission, the hemoglobin was 5 g per dL (50 g/L), the reticulocytes were 35 percent (0.350), the direct antiglobulin test was strongly positive for IgG and C3d (mixed fields),...

journal_title：Transfusion

authors： Gallagher NI,Schergen AK,Sokol-Anderson ML,Sheahan EJ,Chaplin H

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Most patients with severe aplastic anemia (sAA) respond to immunosuppression, but a significant number relapse or develop clonal abnormalities such as paroxysmal nocturnal hemoglobinuria, myelodysplasia, or leukemia. In principle, patients without matched sibling donors and older patients might benefit from ...

journal_title：Transfusion

authors： Sloand EM,Read EJ,Scheinberg P,Tang Y,More K,Leitman SF,Maciejewski J,Young NS

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The performance of the recently launched Procleix Ultrio (Chiron/Gen-Probe) human immunodeficiency virus-1 (HIV-1), hepatitis C virus (HCV), and hepatitis B virus (HBV) blood screening assay was evaluated in a European multicenter study. STUDY DESIGN AND METHODS:Serial dilutions of reference materials were ...

journal_title：Transfusion

authors： Koppelman MH,Assal A,Chudy M,Torres P,de Villaescusa RG,Reesink HW,Lelie PN,Cuypers HT

更新日期：2005-08-01 00:00:00

abstract：:After immunization with native human red cells and red cells infected with Plasmodium falciparum, mouse splenocytes were fused with a myeloma cell line to obtain hybridomas. Among the antibodies specific for blood group antigens, four antibodies (iB3C4, F12, MR432, and iB4) directed against epitopes related to the Rh ...

journal_title：Transfusion

authors： Rouger P,Edelman L

更新日期：1988-01-01 00:00:00

abstract：:Platelet concentrates were prepared by plateletpheresis using discontinuous flow centrifugation. Platelet units were stored in PL-146 bags of 300 ml and 2,000 ml capacity, and in vitro measures helpful in predicting platelet viability were compared. Storage in bags of 300 ml capacity led to significant fall in pH, dec...

journal_title：Transfusion

authors： Katz A,Houx J,Ewald L

更新日期：1978-03-01 00:00:00

abstract：:The biochemical constituents of a 30-year-old sealed bottle of lyophilized plasma were analyzed. The results in this communication show that the process of lyophilization and storage has not seemed to cause any great changes in plasma components, including hormones, enzymes, and proteins. ...

journal_title：Transfusion

authors： Fu P,Myhre B

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The Lu(b) antigen is expressed on red blood cells (RBCs) of the majority of individuals in all populations. Its absence in transfused patients may lead to alloantibody production and mild-to-moderate transfusion reactions, and in pregnancies to mild hemolytic disease of the fetus and newborn. This report des...

journal_title：Transfusion

authors： Garcia-Sanchez F,Pardi C,Kupatawintu P,Thornton N,Rodriguez MA,Lucea I,Sood C,Ochoa-Garay G

更新日期：2016-06-01 00:00:00

abstract：:Critically ill neonatal infants receive frequent small-volume red cell (RBC) transfusions for replacement of blood drawn for laboratory analysis or for treatment of symptomatic anemia secondary to underlying medical conditions and/or a relative bleeding diathesis. Retrospective review of transfusion practice in a hosp...

journal_title：Transfusion

authors： Cook S,Gunter J,Wissel M

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Despite the clinical significance of red blood cell (RBC) alloantibodies, there are currently no laboratory tests available to predict which patients may be at risk of antibody formation after transfusion exposure. Given their phagocytic and inflammatory functions, we hypothesized that differences in circula...

journal_title：Transfusion

authors： Balbuena-Merle R,Curtis SA,Devine L,Gibb DR,Karafin MS,Luckey CJ,Tormey CA,Siddon AJ,Roberts JD,Hendrickson JE

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Obstetric services depend on the transfusion service (TS) to provide diagnostic testing and blood component therapy for clinical care pathways. STUDY DESIGN AND METHODS:We describe three quality improvement (QI) initiatives implemented to improve TS support of obstetric services. RESULTS:We implemented a p...

journal_title：Transfusion

authors： Goodnough LT,Daniels K,Wong AE,Viele M,Fontaine MF,Butwick AJ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:A novel apheresis procedure for a blood separator (MCS+, Haemonetics) enables the collection of 2 WBC-reduced RBC units in a single donation by using one disposable set with one in-line WBC-reduction filter (RC2H, Pall Corp.). The objective of this study was to evaluate the filtration performance in connecti...

journal_title：Transfusion

authors： Bandarenko N,Rose M,Kowalsky RJ,Baston RK,Brecher ME,Elfath MD,Whitley P,Heminway M,Holme S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The Verax PGD rapid test for bacteria in platelets (PLTs) has been updated to simplify workflow and improve specificity and sensitivity by employing a novel sequential format. The performance of this updated version, called PGDprime, was evaluated to determine its suitability for use as an FDA-cleared "safet...

journal_title：Transfusion

authors： Vallejo RP,Shinefeld L,LaVerda D,Best N,Lawrence G,Lousararian A,Hornbaker N,Rasmusson P,Mintz PD

更新日期：2020-11-01 00:00:00

abstract：:A procedure is described for the large-scale production of pure suspensions of human lymphocytes and granulocytes. Platelet-poor buffy-coats, obtained by centrifugation of six units of ABO-compatible ACD blood, were pooled and centrifuged again, resulting in a crude leukocyte concentrate containing approximately 60 pe...

journal_title：Transfusion

authors： de la Rivière AB,Verhoef-Karssen PR,de Wit JJ,Loos JA,Prins HK

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Patients with acute myeloid leukemia (AML) with hyperleukocytosis of at least 100 x 10(9) per L are at high risk of early death due to pulmonary or cerebral leukostasis. Although the efficacy of leukapheresis in terms of prompt cytoreduction is generally accepted, published data regarding the clinical value ...

journal_title：Transfusion

authors： Bug G,Anargyrou K,Tonn T,Bialleck H,Seifried E,Hoelzer D,Ottmann OG

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is an accepted method to prevent some transfusion-transmitted hepatitis B virus (HBV) infections. However, anti-HBc testing may result in donor loss due to unspecific results in the currently available anti-HBc tests. Alg...

journal_title：Transfusion

authors： Juhl D,Luhm J,Görg S,Ziemann M,Hennig H

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA,Houtz T

更新日期：1994-02-01 00:00:00

abstract：:A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

journal_title：Transfusion

authors： Ellisor SS,Shoemaker MM,Reid ME

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Qualification of a cord blood bank (CBB) is a complex process that includes evaluation of multiple aspects of donor screening and testing, processing, accreditation and approval by professional cell therapy groups, and results of received cord blood units. The University of Minnesota Medical Center Cell Ther...

journal_title：Transfusion

authors： Rabe F,Kadidlo D,Van Orsow L,McKenna D

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recent retrospective studies indicate that D- recipients of D+ apheresis platelets (PLTs) are not alloimmunized to D. Our hospital policy is to offer RhIG to D- women of childbearing age who received D+ apheresis PLTs but not to other D- recipients of D+ apheresis PLTs. We instituted prospective surveillance...

journal_title：Transfusion

authors： Weinstein R,Simard A,Ferschke J,Vauthrin M,Bailey JA,Greene M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The potential hemostatic effect of infusible platelet membranes (IPM; Cyplex, Cypress Bioscience) prepared from outdated human platelets is investigated. STUDY DESIGN AND METHODS:Increasing concentrations of IPM were added to blood samples anticoagulated with low-molecular-weight heparin, in which platelets...

journal_title：Transfusion

authors： Galán AM,Bozzo J,Hernández MR,Pino M,Reverter JC,Mazzara R,Escolar G,Ordinas A

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Determination of the white cell (WBC) count in WBC-reduced platelet components requires methods that have a detection limit in the range of approximately 5.0 x 10(2) to 5.0 x 10(4) per mL. STUDY DESIGN AND METHODS:With a 50-microL Nageotte hemocytometer and bright-field microscopy (200x magnification), stud...

journal_title：Transfusion

authors： Moroff G,Eich J,Dabay M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:On rare occasions, upon thawing of stored cryoprecipitate components, clots are observed on visual inspection. Although it has been assumed that the clot reflects fibrinogen to fibrin conversion, there are few published studies that document that this assumption is correct. Our studies were conducted to furt...

journal_title：Transfusion

authors： MacPhee M,Wilmer B,Beall D,Moroff G

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Full siblings were compared with half-siblings to observe how well the two relationships could be distinguished by informative tests. STUDY AND DESIGN METHODS: Parentage analysis ascertained 25 pairs of full siblings and 25 pairs of half-siblings. The pairs were then examined for the sharing of alleles at th...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

journal_title：Transfusion

authors： González R,Echevarria JM,Avellón A,Barea L,Castro E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Cardiothoracic surgery places significant demands on blood bank resources. Measures aimed at reducing intraoperative hemodilution were initiated as part of a blood conservation program. STUDY DESIGN AND METHODS:We initiated a series of measures aimed at reducing hemodilution volume: 1) reduction of intraven...

journal_title：Transfusion

authors： Tran MH,Lin DM,Wilcox T,Schiro D,Cannesson M,Milliken J

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:A reduction in postoperative length of stay (PLOS) was recently demonstrated with the use of leukoreduced (LR) blood in cardiac surgery patients compared to a historical cohort who received non-LR blood. Follow-up data are now presented in a similar population after a 12-month period in which LR blood was no...

journal_title：Transfusion

authors： Fung MK,Moore K,Ridenour M,Mook W,Triulzi DJ

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Currently, donors may arrive at blood collection sites without prior knowledge of eligibility and deferral criteria. STUDY DESIGN AND METHODS:The effects of distributing newly developed recruitment brochures 2 weeks in advance of blood drives and the provision of brochures on temporary deferral at the takin...

journal_title：Transfusion

authors： Gimble JG,Kline L,Makris N,Muenz LR,Friedman LI

更新日期：1994-07-01 00:00:00