Freeze-dried plasma stability under prehospital field conditions.

abstract：BACKGROUND:Thromboelastography (TEG) is widely used in hospitals but less commonly in blood banks for evaluation of platelet (PLT) concentrates (PCs). A TEG-PC assay for testing fresh or stored PLTs must reflect the quality of the PLTs. The added value could be measurement of donor-dependent PLT quality. STUDY DESIGN ...

journal_title：Transfusion

authors： Bontekoe IJ,van der Meer PF,de Korte D

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Peripheral blood white cells (leukocytes) (PBLs) have been used as effective targets for genetic manipulation by transduction with retroviruses in open systems. A semi-closed hollow-fiber bioreactor was tested for culturing and transducing lymphocytes. STUDY DESIGN AND METHODS:PBLs were isolated from five h...

journal_title：Transfusion

authors： Shankar R,Whitley CB,Pan D,Burger S,McCullough J,Stroncek D

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:When bacteria are found, after a platelet transfusion, in the recipient's blood as well as in the platelet concentrate (PC), a causal relationship is normally suspected, with the PC as the causative agent. The other alternative, that the patient has bacteremia and contaminated the PC, is less well documented...

journal_title：Transfusion

authors： Engstrand M,Engstrand L,Högman CF,Hambraeus A,Branth S

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Transfusion-transmitted babesiosis (TTB) has been rapidly increasing in incidence since the beginning of the 21st century. Asymptomatic individuals with Babesia infection are able to donate blood in the United States because of the lack of specific blood donation testing. Blood products collected in Babesia-...

journal_title：Transfusion

authors： LeBel DP 2nd,Moritz ED,O'Brien JJ,Lazarchick J,Tormos LM,Duong A,Fontaine MJ,Squires JE,Stramer SL

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is due to maternal alloimmunization against fetal platelet (PLT) antigens. Antenatal management strategies have been developed to avoid complications such as intracranial hemorrhage. The aim of this study was to set up two reliable, noninvasive fetal gen...

journal_title：Transfusion

authors： Le Toriellec E,Chenet C,Kaplan C

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:There is growing interest in radio frequency identification (RFID) technology application for tracking blood products to achieve higher productivity and safety in the transfusion medicine supply chain. We have conducted a limited study to assess the temperature and biological effects of 13.56 MHz RF radiatio...

journal_title：Transfusion

authors： Davis R,Gottschall J,Gutierrez A,Hohberger C,Veeramani D,Holcombe J

更新日期：2010-07-01 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The term platelet storage lesion (PSL) describes the structural and biochemical changes in platelets (PLTs) during storage. These are typified by alterations of morphologic features and PLT metabolism leading to reduced functionality and hence reduced viability for transfusion. While the manifestations of th...

journal_title：Transfusion

authors： Schubert P,Thon JN,Walsh GM,Chen CH,Moore ED,Devine DV,Kast J

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is reported to occur at an incidence of 5.2% to 23.5% among patients with thalassemia requiring chronic transfusion. With very limited data on alloimmunization among the Chinese population, a territory-wide study has been performed to look at its prevalence among Chinese...

journal_title：Transfusion

authors： Cheng CK,Lee CK,Lin CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron stores expressed as fe...

journal_title：Transfusion

authors： Rigas AS,Berkfors AA,Pedersen OB,Sørensen E,Nielsen KR,Larsen MH,Paarup HM,Wandall HH,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

journal_title：Transfusion

authors： Rios J,Westra J,Dy B,Young PP

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Recombinant activated factor VII (rFVIIa) is being tested to improve hemostasis in a variety of bleeding disorders. Clinical indications and efficacy are still being evaluated for this product. CASE REPORT:Over a 17-month period, rFVIIa was used to treat central nervous system hemorrhage in three patients w...

journal_title：Transfusion

authors： Huang WY,Kruskall MS,Bauer KA,Uhl L,Shaz BH

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Proteomics methods may be used to analyze changes occurring in stored blood products. These data sets can identify processes leading to storage-associated losses of blood component quality such as the platelet (PLT) storage lesion (PSL). The optimal strategy to perform such analyses to obtain the most inform...

journal_title：Transfusion

authors： Thon JN,Schubert P,Duguay M,Serrano K,Lin S,Kast J,Devine DV

更新日期：2008-03-01 00:00:00

abstract：:The platelets used in this study were collected by serial centrifugation, and within four hours of collection were frozen with 5% dimethylsulfoxide (DMSO) at an overall rate of 2 to 3 C per minute by storage in a mechanical refrigerator at -80 C. The frozen platelets were stored for four to ten weeks before thawing an...

journal_title：Transfusion

authors： Zaroulis CG,Spector JI,Emerson CP,Valeri CR

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

journal_title：Transfusion

authors： Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Standard plateletpheresis techniques and effects on platelet (PLT) donors were investigated to provide an informative basis for advancement of apheresis software. STUDY DESIGN AND METHODS:Three paired groups with 33 male and 22 female blood donors were prospectively investigated by analyzing blood counts of...

journal_title：Transfusion

authors： Strasser EF,Schuster M,Egler K,Bauer J,Weisbach V,Ringwald J,Zimmermann R,Zingsem J,Eckstein R

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Much effort and resources have been devoted to programs that provide transfusion support for patients with sickle cell disease (SCD). The focus of many donor programs is to prevent alloimmunization by recruiting racially matched African American donors to limit the red blood cell (RBC) antigenic differences ...

journal_title：Transfusion

authors： Karafin MS,Field JJ,Gottschall JL,Denomme GA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecules on RBCs may regulate ...

journal_title：Transfusion

authors： Khandelwal S,van Rooijen N,Saxena RK

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Transfusion safety rests heavily on the health of blood donors. Although they are perceived as being healthier than average, little is known about their long-term disease patterns and to which extent the blood banks' continuous efforts to optimize donor selection has resulted in improvements. Mortality and c...

journal_title：Transfusion

authors： Edgren G,Tran TN,Hjalgrim H,Rostgaard K,Shanwell A,Titlestad K,Wikman A,Norda R,Jersild C,Wideroff L,Gridley G,Adami J,Melbye M,Nyrén O,Reilly M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Supply of cytomegalovirus (CMV)-seronegative blood products in Australia is an ongoing challenge. Requests for CMV-negative products are increasing with prediction that the demand will exceed supply by 2019. Clinical information evaluating how these products are being utilized by health providers within Aust...

journal_title：Transfusion

authors： Hirani R,Tohidi-Esfahani I,Mondy P,Irving DO

更新日期：2018-03-01 00:00:00

abstract：:The manual Polybrene test described by Lalezari and Jiang was tested in parallel with saline, papain, and antiglobulin tests routinely used in this laboratory for antibody detection and identification and compatibility testing. Among 5381 patient sera tested, 264 antibodies were detected in 244 patients. In all, 6353 ...

journal_title：Transfusion

authors： Fisher GA

更新日期：1983-03-01 00:00:00

abstract：:Anti-Rd (Radin) was first described in association with five cases of hemolytic disease of the newborn. The authors report an anti-Rd that was demonstrated following the transfusion of a Radin positive unit of blood. The antibody appears to be of the IgG immunoglobulin class and increased in titer following the transf...

journal_title：Transfusion

authors： Winn LC,Eska PL,Grindon AJ

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:This study explored the effect of storing packed RBCs suspended in 200 mL of an alkaline, hypotonic, experimental additive solution (EAS 61). STUDY DESIGN AND METHODS:Packed RBC units prepared from RBCs collected from healthy donors in CPD were stored for 8 (n = 10) and 9 (n = 10) weeks under blood bank con...

journal_title：Transfusion

authors： Hess JR,Rugg N,Knapp AD,Gormas JF,Silberstein EB,Greenwalt TJ

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The Am phenotype has been characterized as a weak expression of the A antigen on red blood cells but the presence of a normal quantity of the A antigen in saliva. This study describes a molecular genetic analysis of members of an Am family. STUDY DESIGN AND METHODS:The eight exon regions of the ABO genes of...

journal_title：Transfusion

authors： Lin M,Hou MJ,Twu YC,Yu LC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Five cases of human immunodeficiency virus Type 1 (HIV-1) RNA-positive blood donations are described that escaped detection by three different CE-marked nucleic acid amplification technique (NAT) screening assays. These events were associated with two HIV-1 transmissions to recipients of blood components. Th...

journal_title：Transfusion

authors： Chudy M,Weber-Schehl M,Pichl L,Jork C,Kress J,Heiden M,Funk MB,Nübling CM

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Unpleasant blood donation-related symptoms may discourage otherwise healthy, altruistic individuals from becoming repeat donors. This study examined a behavioral technique called applied muscle tension (AMT) that might reduce reactions. STUDY DESIGN AND METHODS:A total of 605 donors at mobile clinics were a...

journal_title：Transfusion

authors： Ditto B,France CR,Lavoie P,Roussos M,Adler PS

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Qualitative RHD variants are the result of the replacement of RHD exons by their RHCE counterparts or of point mutations in RHD causing amino acid substitutions. For RHD typing, the use of at least two RHD typing polymerase chain reaction (PCR) assays directed at different regions of RHD is advised to preven...

journal_title：Transfusion

authors： Maaskant-van Wijk PA,Faas BH,de Ruijter JA,Overbeeke MA,von dem Borne AE,van Rhenen DJ,van der Schoot CE

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Recombinant human G-CSF is widely used to mobilize PBPCs in healthy donors for allogeneic transplantation. There have been concerns about donor safety because of splenic ruptures during G-CSF application. To address this problem, changes in splenic size in 91 healthy donors during G-CSF mobilization of allog...

journal_title：Transfusion

authors： Platzbecker U,Prange-Krex G,Bornhäuser M,Koch R,Soucek S,Aikele P,Haack A,Haag C,Schuler U,Berndt A,Rutt C,Ehninger G,Hölig K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Maternal iron deficiency anemia (IDA) impacts placenta and fetus. We evaluated effects of IDA at admission for delivery on cesarean rates, and adverse maternal and neonatal outcomes. STUDY DESIGN AND METHODS:Medical records from Jerusalem (2005-2012) identified women with a live-birth singleton fetus in cep...

journal_title：Transfusion

authors： Drukker L,Hants Y,Farkash R,Ruchlemer R,Samueloff A,Grisaru-Granovsky S

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The successful mobilization and collection of hematopoietic stem cells are dependent on a number of clinical factors such as previous chemotherapy and disease stage. The aim of this retrospective study was to determine whether the effectiveness of mobilization and collection is an independent prognostic fact...

journal_title：Transfusion

authors： Wang S,Nademanee A,Qian D,Dagis A,Park HS,Fridey J,Smith E,Snyder D,Somlo G,Stein A,Rosenthal J,Falk P,Kogut N,Palmer J,Gaal K,Kim Y,Bhatia R,Yuan S,Kay C,Weiss L,Forman S

更新日期：2007-12-01 00:00:00