A simplified procedure for deglycerolizing red blood cells frozen in a high glycerol concentration.

abstract：:A technique of platelet concentrate preparation and storage is presented which permits the maximum number of viable and functional platelets to be preserved for periods of 72 hours. Although the storage conditions must be followed precisely, the method is nevertheless simple to perform and does not require specialized...

journal_title：Transfusion

authors： Slichter SJ,Harker LA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The proposal to assess the viability capabilities of platelets (PLTs) collected, treated, or stored in a developmental system against "fresh" PLTs from the same subject poses several important methodologic issues pertaining to the timing and manner of the collecting and separating the fresh PLTs. This study ...

journal_title：Transfusion

authors： AuBuchon JP,Herschel L,Roger J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Human infections with simian foamy viruses (SFVs) have been reported after occupational and nonoccupational exposure to infected animals and their tissues, blood, and body fluids, although there is no evidence for human-to-human transmission. We previously demonstrated SFV transmission in monkeys by blood tr...

journal_title：Transfusion

authors： Williams DK,Khan AS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Although Creutzfeldt-Jakob disease (CJD) has been shown to be transmissible through blood components in rodent models, no human blood-to-blood transmission has been documented. If blood transmission were possible in humans, persons with hemophilia in the United States would be at higher risk of contracting C...

journal_title：Transfusion

authors： Evatt B,Austin H,Barnhart E,Schonberger L,Sharer L,Jones R,DeArmond S

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Blood transfusion has been cited as one of the five most overutilized therapeutic procedures in the United States. We assessed the impact of clinical decision support at computerized physician order entry and education on red blood cell (RBC) transfusions and clinical patient outcomes at our institution. ST...

journal_title：Transfusion

authors： Goodnough LT,Maggio P,Hadhazy E,Shieh L,Hernandez-Boussard T,Khari P,Shah N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Appropriate management to prevent relapses of acquired, autoimmune thrombotic thrombocytopenic purpura (TTP) is not clear. Rituximab (375 mg/m2 /week × 4) is effective treatment for acute episodes but it is not consistently effective for prevention of relapses. Maintenance rituximab, 375 mg/m2 /3 months for ...

journal_title：Transfusion

authors： Saleem R,Rogers ZR,Neunert C,George JN

更新日期：2019-03-01 00:00:00

abstract：:The US Food and Drug Administration (FDA) held a workshop on red blood cell (RBC) product regulatory science on October 6 and 7, 2016, at the Natcher Conference Center on the National Institutes of Health (NIH) Campus in Bethesda, Maryland. The workshop was supported by the National Heart, Lung, and Blood Institute, N...

journal_title：Transfusion

authors： Vostal JG,Buehler PW,Gelderman MP,Alayash AI,Doctor A,Zimring JC,Glynn SA,Hess JR,Klein H,Acker JP,Spinella PC,D'Alessandro A,Palsson B,Raife TJ,Busch MP,McMahon TJ,Intaglietta M,Swartz HM,Dubick MA,Cardin S,Patel

更新日期：2018-01-01 00:00:00

abstract：:With the advent of remote damage control resuscitation and far-forward surgery, a renewed emphasis has been placed on examining a variety of pharmacologic adjuncts to controlling blood loss before definitive operative intervention. In this paper, the authors review the current state of the art for tranexamic acid (TXA...

journal_title：Transfusion

authors： Rappold JF,Pusateri AE

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In experimental pneumonia we found that transfused older blood increased mortality and lung injury that was associated with increased in vivo hemolysis and elevated plasma cell-free hemoglobin (CFH), non-transferrin-bound iron (NTBI), and plasma labile iron (PLI) levels. In this study, we additionally analyz...

journal_title：Transfusion

authors： Wang D,Cortés-Puch I,Sun J,Solomon SB,Kanias T,Remy KE,Feng J,Alimchandani M,Quezado M,Helms C,Perlegas A,Gladwin MT,Kim-Shapiro DB,Klein HG,Natanson C

更新日期：2014-07-01 00:00:00

abstract：:In spite of growing awareness of the potential risks associated with transfusion, the number of platelet units transfused in the United States continues to increase each year. There is a growing interest in ensuring that all transfusions are administered for appropriate reasons. Prospective review of requests for tran...

journal_title：Transfusion

authors： Sielaff BH,Scott EP,Connelly DP

更新日期：1991-09-01 00:00:00

abstract：:Many strains of Escherichia coli possess an antigen that reacts with naturally occurring antibodies to human red cell B antigens. The authors tested the hypothesis that the presence of naturally occurring anti-B isoagglutinins afford protection against the development of E. coli septicemia. The blood groups found in 1...

journal_title：Transfusion

authors： Wittels EG,Lichtman HC

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Identification of antibodies against high-prevalence Scianna (Sc; ERMAP) antigens, like Sc1 and Sc5, is difficult and may incur delays in blood procurement and costs. The detection of additional clinically significant alloantibodies is hampered in the presence of anti-Scianna. Soluble recombinant Scianna pro...

journal_title：Transfusion

authors： Seltsam A,Grueger D,Blasczyk R,Flegel WA

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Bleeding into the chest is a life-threatening complication of cardiac surgery. Blood transfusion has been implicated as an important cause of harm associated with bleeding, based largely on studies demonstrating an independent association between transfusion and mortality. These studies did not, however, con...

journal_title：Transfusion

authors： Dixon B,Santamaria JD,Reid D,Collins M,Rechnitzer T,Newcomb AE,Nixon I,Yii M,Rosalion A,Campbell DJ

更新日期：2013-01-01 00:00:00

abstract：:A stable mouse hybridoma line secreting monoclonal anti-C3d antibody (NBTS/BRIC 8) was produced. Ascitic fluid containing BRIC 8 can be used at a final dilution of 1 to 5000 to provide an excellent antiglobulin reagent when mixed with a conventional polyclonal rabbit anti-human IgG serum. ...

journal_title：Transfusion

authors： Holt PD,Donaldson C,Judson PA,Johnson P,Parsons SF,Anstee DJ

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:RhIG is obtained from hyperimmunized healthy anti-D donors (HIDs) boosted with D+ red blood cells (RBCs). One hypothesis for its mechanism of action is fast clearance of opsonized D+ RBCs through Fcγ receptor (FcγR)III. Levels of immunoglobulin (Ig)G Fc-fucosylation influence interactions with FcγRIII, with ...

journal_title：Transfusion

authors： Kapur R,Della Valle L,Verhagen OJ,Hipgrave Ederveen A,Ligthart P,de Haas M,Kumpel B,Wuhrer M,van der Schoot CE,Vidarsson G

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Proinflammatory cytokines were measured in the supernatant portion of stored, bacterially contaminated, and/or white cell (WBC)-reduced units of red cells (RBCs). Previous studies from this laboratory and others have shown that cytokines are generated in platelet concentrates during storage. This earlier wor...

journal_title：Transfusion

authors： Stack G,Baril L,Napychank P,Snyder EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Unexpected antibodies are frequently associated with hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs), and screening for those unexpected antibodies is critical for the safety and effectiveness of transfusion. Different populations differ in the prevalence of signi...

journal_title：Transfusion

authors： Chen C,Tan J,Wang L,Han B,Sun W,Zhao L,Huang C,Tan B,Qin L

更新日期：2016-04-01 00:00:00

abstract：:The morphology of granulocytes collected by continuous-flow centrifugation (CFC), discontinuous-flow centrifugation (DFC), and continuous-flow filtration (CFF) was investigated in 18 healthy donors by means of light microscopy and transmission electron microscopy. Light microscopy study of semithin sections of granulo...

journal_title：Transfusion

authors： Feliu E,Woessner S,Matutes E,Cardellach F,Grañena A,Marin P,Puig L,Vives-Corrons JL,Montserrat E,Rozman C

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess functionality and resources of facilities providing blood collection and transfusion services in Afghanistan. STUDY DESIGN AND METHODS:This national cross-sectional assessment included facilities collecting or transfusing blood identified through official data sources...

journal_title：Transfusion

authors： Mansoor GF,Rahmani AM,Kakar MA,Hashimy P,Abrahimi P,Scott PT,Peel SA,Rentas FJ,Todd CS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A system has been developed to inactivate a wide spectrum of blood-borne pathogens in red blood cells (RBCs) before transfusion. The system utilizes S-303 to target nucleic acids of pathogens and white blood cells. The safety of pathogen inactivated RBC was assessed using S-303-treated RBCs (S-303 RBCs) and ...

journal_title：Transfusion

authors： North A,Ciaravino V,Mufti N,Corash L

更新日期：2011-10-01 00:00:00

abstract：:We describe a nonanaphylactic hemoglobinuric reaction caused by transfusion of frozen red cells, deglycerolyzed by standard technique, obtained from a donor with undiagnosed sickle trait. Although significant hemoglobinemia and hemoglobinuria were noted, the recipient experienced no adverse clinical reactions. The ben...

journal_title：Transfusion

authors： Kelleher JF Jr,Luban NL

更新日期：1984-03-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Most alloantigens on transfused red blood cells (RBCs) are weakly immunogenic, with only a 2 to 6 percent overall immunization rate even in patients receiving multiple transfusions. Although recipient genetics may contribute to responder and/or nonresponder status, in most cases HLA type does not predict hum...

journal_title：Transfusion

authors： Hendrickson JE,Desmarets M,Deshpande SS,Chadwick TE,Hillyer CD,Roback JD,Zimring JC

更新日期：2006-09-01 00:00:00

abstract：:Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward. ...

journal_title：Transfusion

authors： Daniels GL,Judd WJ,Moore BP,Neitzer G,Ouellet P,Plantos M,Verrette S

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:JMH is a high-frequency red cell blood group antigen that resides on a 76- to 80-kDa glycosylphosphatidylinositol-linked protein also known as CDw108. Antibodies with JMH specificity are often autoimmune and are usually, if not always, clinically benign. Some individuals with JMH-variant antigen produce allo...

journal_title：Transfusion

authors： Mudad R,Rao N,Issitt PD,Roy RB,Combs MR,Telen MJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) bas...

journal_title：Transfusion

authors： Poiesz BJ,Dube S,Jones B,Bryz-Gornia V,Dean MT,Spicer T,Hengst J,Sayre K,Esteban E,Ferrer JF

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Erythrocytapheresis (ECP), automated red blood cell exchange, is increasingly being used for chronic transfusion therapy in sickle cell disease (SCD) as it is an isovolumetric transfusion, is more effective in lowering hemoglobin (Hb)S, and can limit iron overload. Because ECP requires increased blood exposu...

journal_title：Transfusion

authors： Wahl SK,Garcia A,Hagar W,Gildengorin G,Quirolo K,Vichinsky E

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Because single-donor plateletpheresis concentrates now account for a large percentage of PLT concentrates, the PLT quality of individual donations is increasingly important. There has been little previous work on PLT function in blood donors. STUDY DESIGN AND METHODS:The aim of this study was to investigate...

journal_title：Transfusion

authors： Harrison P,Segal H,Furtado C,Verjee S,Sukhu K,Murphy MF

更新日期：2004-05-01 00:00:00

abstract：:We have estimated the risk of transmitting HIV infection from a unit of HIV seronegative blood collected in Los Angeles and Orange Counties, CA from March 1985 through February 1987. Our method consisted of lookback investigations and anti-HIV testing of living recipients of HIV seronegative units donated by persons w...

journal_title：Transfusion

authors： Kleinman S,Secord K

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:The clinical significance of alloimmunization to RBC antigens in sickle cell patients was analyzed by a retrospective review of the records of pediatric and adult sickle cell patients who received transfusions and who were followed over a 10-year period. STUDY DESIGN AND METHODS:Charts of pediatric and adul...

journal_title：Transfusion

authors： Aygun B,Padmanabhan S,Paley C,Chandrasekaran V

更新日期：2002-01-01 00:00:00