High incidence of defective high-shear platelet function among platelet donors.

abstract：:Immune-deficient patients depend on the antibodies in pooled human immunoglobulin G (IgG) preparations to remain free from serious infections. The potency of IgG preparations is therefore an ongoing concern. The use of pooled IgG to prevent infection is based on the concept that healthy adults have recovered from infe...

journal_title：Transfusion

authors： Berger M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:A storage period of 42 days has been approved by the FDA for RBCs stored in NUTRICEL (AS-3). This study was undertaken to provide data to the FDA about the feasibility of salvaging AS-3 RBCs at the end of their storage period by rejuvenation and freezing, and to evaluate the effect of rejuvenation on indicat...

journal_title：Transfusion

authors： Lockwood WB,Hudgens RW,Szymanski IO,Teno RA,Gray AD

更新日期：2003-11-01 00:00:00

abstract：:Alloagglutinins of M and N specificites with unique characteristics found in normal sera are described. Specific M or N agglutination by these sera occurred only when erythrocytes had been exposed to glucose-containing solutions. Conversion to the form of MN recognized by these sera required incubation of the cells in...

journal_title：Transfusion

authors： Morel PA,Bergren MO,Hill V,Garratty G,Perkins HA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is an accepted method to prevent some transfusion-transmitted hepatitis B virus (HBV) infections. However, anti-HBc testing may result in donor loss due to unspecific results in the currently available anti-HBc tests. Alg...

journal_title：Transfusion

authors： Juhl D,Luhm J,Görg S,Ziemann M,Hennig H

更新日期：2011-07-01 00:00:00

abstract：:The possible beneficial role of white cells (WBCs) in donor blood has been investigated with respect to their capacity to remove bacteria. Preparations of buffy coat and whole blood, containing as well as reduced of WBCs, were inoculated with Staphylococcus epidermidis, S. aureus, Escherichia coli, Pseudomonas aerugin...

journal_title：Transfusion

authors： Högman CF,Gong J,Eriksson L,Hambraeus A,Johansson CS

更新日期：1991-09-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：:To study red cell transfusion practice in 3216 coronary artery bypass graft (CABG) cases in 11 hospitals in 1988, abstracted patient records were stratified by diagnosis related group (DRG) (that is, DRG 106, coronary artery bypass without catheterization, or DRG 107, coronary artery bypass with catheterization) and I...

journal_title：Transfusion

authors： Surgenor DM,Wallace EL,Churchill WH,Hao SH,Chapman RH,Collins JJ Jr

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA,Houtz T

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The aim of this study was to assess the sensitivity and specificity of a n...

journal_title：Transfusion

authors： Chang CD,Cheng KY,Jiang LX,Salbilla VA,Haller AS,Yem AW,Bryant JD,Kirchhoff LV,Leiby DA,Schochetman G,Shah DO

更新日期：2006-10-01 00:00:00

abstract：:Lyophilized factor VIII concentrates, because of their convenience, are the most commonly used products for providing antihemophilic factor to patients with hemophilia A. Heightened concerns about associated complications indicate that cryoprecipitate usage will increase in the immediate future. We present a protocol ...

journal_title：Transfusion

authors： Menitove JE,Spero JA,Richards WA,Lewis JH,Montgomery RR,Gill JC,Hasiba U,Wheeler DV,Sherwin JA,Russell-Vaskov S,Marlar RA,Maxwell NG,Aster RH

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Drug-induced immune thrombocytopenia (DITP) is a serious, life-threatening clinical syndrome, the diagnosis of which is consistently difficult. In this report, we present a case of DITP caused by meropenem that was confirmed by laboratory tests. CASE REPORT:A 59-year-old male patient developed severe thromb...

journal_title：Transfusion

authors： Huang R,Cai GQ,Zhang JH,Liu FX,Ma JQ,Liu H,Nie XM,Gui R

更新日期：2017-11-01 00:00:00

abstract：:This review considers the various methods currently in use, or under investigation, for the storage of platelets intended for use in the treatment of active hemorrhage. The current standard practice of storing platelets at room temperature (RT) (20°C-24°C) optimizes circulating time, but at the expense of hemostatic f...

journal_title：Transfusion

authors： Milford EM,Reade MC

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies have been shown to be effective in decreasing red blood cell (RBC) utilization in specific patient groups. However, few data exist describing the extent of RBC transfusion reduction or their impact on transfusion practice and mortality in a diverse inpatient population. STUDY D...

journal_title：Transfusion

authors： Roubinian NH,Escobar GJ,Liu V,Swain BE,Gardner MN,Kipnis P,Triulzi DJ,Gottschall JL,Wu Y,Carson JL,Kleinman SH,Murphy EL,NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) bas...

journal_title：Transfusion

authors： Poiesz BJ,Dube S,Jones B,Bryz-Gornia V,Dean MT,Spicer T,Hengst J,Sayre K,Esteban E,Ferrer JF

更新日期：1997-01-01 00:00:00

abstract：:This paper presents recent data from quantitative and thermodynamic investigations on A and B erythrocyte antigens. In regard to weak A phenotypes on the basis of quantitative data, practically no gap is observed from the weakest Aend to the strongest A3. Weak B phenotypes give a similar distribution. However, a more ...

journal_title：Transfusion

authors： Salmon C,Lopez M,Cartron JP,Bouguerra A

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:RBCs can be frozen with either the high-glycerol method (HGM) or the low-glycerol method (LGM). To date, the use of frozen RBCs is hampered by a 24-hour outdating period after thawing. A closed washing system (ACP 215) may solve this problem. STUDY DESIGN AND METHODS:We compared the effects of high- (40%) a...

journal_title：Transfusion

authors： Lelkens CC,Noorman F,Koning JG,Truijens-de Lange R,Stekkinger PS,Bakker JC,Lagerberg JW,Brand A,Verhoeven AJ

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Antibodies to Mia , MUT, and Mur are among the most frequently identified alloantibodies in Southeast Asia. Understanding the characteristics of these antibodies in terms of induction and evanescence would aid in optimizing methods for their detection. STUDY DESIGN AND METHODS:Antibody testing results betwe...

journal_title：Transfusion

authors： Nadarajan VS

更新日期：2018-05-01 00:00:00

abstract：:Baboons were bled one-third of their blood volume and then transfused with an equivalent volume of compatible donor red blood cells with 160 per cent of normal 2,3-diphosphoglycerate (2,3-DPG) levels and improved capacity to release oxygen to tissue. The mixture of baboon donor-recipient red blood cells in the circula...

journal_title：Transfusion

authors： Zaroulis CG,Pivacek LE,Lowrie GB,Valeri CR

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis G virus (HGV) and its strain variant, the GB agent (GBV-C) is high in non-virus-inactivated plasma products, but, persistent infection in recipients is relatively low. STUDY DESIGN AND METHODS:Stored samples from transfusion donors and recipients in a prospective study of posttra...

journal_title：Transfusion

authors： Wang JT,Chen PJ,Liu DP,Sheu JC,Wang TH,Chen DS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Very preterm newborns receive up to three to five red blood cell (RBC) transfusions, often early, after birth. Despite awareness of the association of transfusion with increases in cytokines and markers of endothelial activation, research has focused on single transfusions weeks after birth. With pathophysio...

journal_title：Transfusion

authors： Crawford TM,Andersen CC,Stark MJ

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versus-host disease (TA-GVHD) involves patient exposure to donor platelets (PLTs) and T lymphocytes, respectively, which are removed during blood component leukodepletion (LD). STUDY DESIGN AND METHODS:Reports of PTP and TA-G...

journal_title：Transfusion

authors： Williamson LM,Stainsby D,Jones H,Love E,Chapman CE,Navarrete C,Lucas G,Beatty C,Casbard A,Cohen H

更新日期：2007-08-01 00:00:00

abstract：:Anemia is common in pregnant women and is associated with increased morbidity for the mother and the fetus, including increased risk of allogeneic blood transfusion. Iron deficiency is the most common etiology for anemia during pregnancy. Oral iron therapy remains the standard treatment but is often poorly tolerated d...

journal_title：Transfusion

authors： Guinn NR,Cooter ML,Maisonave Y,Grimsley A,Cellura C,Grotegut CA,Lamon A,Aronson S,Duke Perioperative Enhancement Team (POET).

更新日期：2020-11-01 00:00:00

abstract：:A fluorometric assay is described for the detection of red blood cell antibodies. The assay reveals as little as 600 molecules of bound, fluoresceinated rabbit anti-human IgG antibodies per erythrocyte. Eleven patients with possible autoimmune erythrocyte disorder and negative direct antiglobulin test were studied by ...

journal_title：Transfusion

authors： Schreiber AB,Lambermont M,Strosberg AD,Wybran J

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) are the most potent antigen-presenting cells that initiate and regulate immune responses. They are unique in their feature to produce bioactive interleukin (IL)-12, a major proinflammatory cytokine connecting innate and adaptive immunity. Platelets (PLTs) are highly reactive components ...

journal_title：Transfusion

authors： Kissel K,Berber S,Nockher A,Santoso S,Bein G,Hackstein H

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The testing of cord blood (CB) progenitor and stem cell units for transplantation suitability involves enumeration of total nucleated cells before freezing. CD34+ cell counts may also be a means of determining suitability. Studies have been conducted to evaluate how specific storage conditions influence cell...

journal_title：Transfusion

authors： Kurtz J,Seetharaman S,Greco N,Moroff G

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Iron supplements reduce the risk of iron depletion in blood donors. Recent initiatives have sought to increase use of donor iron supplementation (IS), but a baseline description of blood donor supplement practices is needed. STUDY DESIGN AND METHODS:Presenting blood donors received a questionnaire inquiring...

journal_title：Transfusion

authors： Cable RG,Spencer BR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The rehydrated, lyophilized (RL) platelet (PLT) is being developed as a hemostatic infusion agent for the control of active bleeding. The key to the method for preparing RL PLTs is a mild aldehyde stabilization that allows for freezing and lyophilizing without cellular rupture. RL PLTs have been shown to be ...

journal_title：Transfusion

authors： Fischer TH,Bode AP,Parker BR,Russell KE,Bender DE,Ramer JK,Read MS

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The diagnosis of immune thrombocytopenic purpura (ITP) is a diagnosis of exclusion, as stated by international guidelines. Nevertheless, the assessment of platelet (PLT) antibodies has been reported as helpful for the diagnosis and the follow-up of ITP patients. PLT antibodies are detected by highly speciali...

journal_title：Transfusion

authors： Hézard N,Simon G,Macé C,Jallu V,Kaplan C,Nguyen P

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) can be used as hematopoietic stem cell source for transplantation. The success of a transplantation is highly correlated with the number of total nucleated cells (TNCs) and CD34+ cells in the UCB. Certain obstetric factors increase the yield of stem cells in the UCB. It is necessar...

journal_title：Transfusion

authors： Manegold G,Meyer-Monard S,Tichelli A,Pauli D,Holzgreve W,Troeger C

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00