Comparative morphology of granulocytes collected by three methods of leukapheresis. A light microscopy and transmission electron microscopy study.

abstract：BACKGROUND:Studies have shown that packed blood cells (PBCs) stored in AS-1 (Adsol, Baxter) and AS-3 (Nutricel, Medsep Corp.) accumulate proinflammatory substances, which may contribute to increased complications from allogeneic blood transfusion. This study assessed whether supernates from PBCs stored in AS-5 (Optisol...

journal_title：Transfusion

authors： McFaul SJ,Corley JB,Mester CW,Nath J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Blood transfusion has been cited as one of the five most overutilized therapeutic procedures in the United States. We assessed the impact of clinical decision support at computerized physician order entry and education on red blood cell (RBC) transfusions and clinical patient outcomes at our institution. ST...

journal_title：Transfusion

authors： Goodnough LT,Maggio P,Hadhazy E,Shieh L,Hernandez-Boussard T,Khari P,Shah N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

journal_title：Transfusion

authors： Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Throughout history, blood has been embedded with powerful and paradoxical connotations. In the last decades, a more rational conception based on scientific knowledge has emerged, portraying blood as a "disenchanted" and utilitarian object, hence more apt for donation between strangers. This study aims to exa...

journal_title：Transfusion

authors： Charbonneau J,Tran NY

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is an accepted method to prevent some transfusion-transmitted hepatitis B virus (HBV) infections. However, anti-HBc testing may result in donor loss due to unspecific results in the currently available anti-HBc tests. Alg...

journal_title：Transfusion

authors： Juhl D,Luhm J,Görg S,Ziemann M,Hennig H

更新日期：2011-07-01 00:00:00

abstract：:Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their...

journal_title：Transfusion

authors： Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:To prevent donor loss and improve retention, it is important to understand the major deterrents to blood donation and to identify factors that can be effectively addressed by blood centers. STUDY DESIGN AND METHODS:A 30-item self-administered questionnaire was completed in 2003 by 1705 first-time and 2437 r...

journal_title：Transfusion

authors： Schreiber GB,Schlumpf KS,Glynn SA,Wright DJ,Tu Y,King MR,Higgins MJ,Kessler D,Gilcher R,Nass CC,Guiltinan AM,National Heart, Lung, Blood Institute Retrovirus Epidemiology Donor Study.

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Routine quantification of platelet-derived extracellular vesicles (PL-EVs) may be useful in the quality control (QC) of platelet concentrates (PCs). The aim of this multicenter study was to establish and validate a consensus protocol for the standardized PL-EV quantification using conventional flow cytometer...

journal_title：Transfusion

authors： Black A,Orsó E,Kelsch R,Pereira M,Kamhieh-Milz J,Salama A,Fischer MB,Meyer E,Frey BM,Schmitz G

更新日期：2017-06-01 00:00:00

abstract：:Hospitals are required by accrediting agencies to perform blood utilization review. Specific areas that must be addressed are the ordering, distribution, handling, dispensing, and administration of blood components. Monitoring the effects of transfusion on patients is also required. The format of the review process an...

journal_title：Transfusion

authors： Stehling L,Luban NL,Anderson KC,Sayers MH,Long A,Attar S,Leitman SF,Gould SA,Kruskall MS,Goodnough LT

更新日期：1994-05-01 00:00:00

abstract：:This article introduces a new method of component preparation that is capable of producing white cell (WBC)-reduced platelet concentrates (PCs) from whole blood. Whole blood is separated into packed red cells (RBCs) and platelet-rich plasma (PRP) by centrifugation, and the PRP is expressed through a newly designed WBC...

journal_title：Transfusion

authors： Dzik WH,Cusack WF,Gacek MJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Pulmonary endothelial cell damages caused by neutrophil overactivation could result in acute lung injuries including transfusion-related acute lung injury (TRALI). We previously reported that heme-related molecules derived from hemolysis induced the production of reactive oxygen species from neutrophils. Rec...

journal_title：Transfusion

authors： Kono M,Saigo K,Takagi Y,Takahashi T,Kawauchi S,Wada A,Hashimoto M,Minami Y,Imoto S,Takenokuchi M,Morikawa T,Funakoshi K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:After multiple transfusions, the serologic typing of autologous blood group phenotypes is difficult, because of mixed RBC populations. The genotyping of ABO, Rh, Kell, Kidd, and Duffy systems could be used to determine autologous blood group antigen status. STUDY DESIGN AND METHODS:Blood samples from patien...

journal_title：Transfusion

authors： Rozman P,Dovc T,Gassner C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Virus inactivation of pooled fresh-frozen plasma (FFP) by the solvent/detergent (SD) method results in a loss of approximately 20 percent of factor VIII. This study aimed to assess the efficacy of SD-treated plasma in correcting the coagulopathy associated with liver disease and liver transplantation. STUDY...

journal_title：Transfusion

authors： Williamson LM,Llewelyn CA,Fisher NC,Allain JP,Bellamy MC,Baglin TP,Freeman J,Klinck JR,Ala FA,Smith N,Neuberger J,Wreghitt TG

更新日期：1999-11-01 00:00:00

abstract：:Anti-Ytb was readily eluted from the cord red blood cells of the second child of a mother with both anti-Ytb and anti-Kell in her serum. The baby was Yt (a+b+) and Kell negative. The cord red blood cells were found to have a weakly positive direct antiglobulin test. Clinically evident hemolytic disease of the newborn ...

journal_title：Transfusion

authors： Ferguson SJ,Boyce F,Blajchman MA

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Infectious events have been reported as major environmental triggers of thrombotic thrombocytopenic purpura (TTP). We detail here the potential association between infections and TTP. STUDY DESIGN AND METHODS:We recruited randomly and prospectively a cohort of 280 consecutive TTP patients during a 9-year pe...

journal_title：Transfusion

authors： Morgand M,Buffet M,Busson M,Loiseau P,Malot S,Amokrane K,Fortier C,London J,Bonmarchand G,Wynckel A,Provôt F,Poullin P,Vanhille P,Presne C,Bordessoule D,Girault S,Delmas Y,Hamidou M,Mousson C,Vigneau C,Lautrette A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Among labile blood products, platelet concentrates (PCs) are the leading cause of hypersensitivity transfusion reactions (HTRs). These reactions often lead to interruption of PC transfusion and can result in a prolonged transfusion process leading to significant morbidity and use of premedication and close m...

journal_title：Transfusion

authors： Mertes PM,Tacquard C,Andreu G,Kientz D,Gross S,Malard L,Drouet C,Carlier M,Gachet C,Sandid I,Boudjedir K

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

journal_title：Transfusion

authors： Wallis JP,Lubenko A,Wells AW,Chapman CE

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Blood banks ensure the safety of blood components by testing them for a set of known infectious agents and by careful selection of donors based on a self-administered questionnaire and an interview. The purpose of this study is to describe the risk behavior for sexually transmitted diseases in Norwegian bloo...

journal_title：Transfusion

authors： Stigum H,Bosnes V,Ørjasaeter H,Heier HE,Magnus P

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:There is evidence that physicians lack adequate transfusion medicine knowledge. To design needs-based educational interventions to address this gap, a validated assessment tool is required. Previously published exams have not been created or validated using rigorous psychometric methods. STUDY DESIGN AND ME...

journal_title：Transfusion

authors： Haspel RL,Lin Y,Fisher P,Ali A,Parks E,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Effective donor skin disinfection is essential in preventing bacterial contamination of blood components with skin flora bacteria like Staphylococcus epidermidis. Cell aggregates of S. epidermidis (biofilms) are found on the skin and are resistant to the commonly used donor skin disinfectants chlorhexidine-g...

journal_title：Transfusion

authors： Alabdullatif M,Boujezza I,Mekni M,Taha M,Kumaran D,Yi QL,Landoulsi A,Ramirez-Arcos S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The storage duration of platelet (PLT) units is limited to 5 to 7 days. This study investigates whether PLT storage duration is associated with patient outcomes in critically ill patients. STUDY DESIGN AND METHODS:This study was a retrospective analysis of critically ill patients admitted to the intensive c...

journal_title：Transfusion

authors： Flint A,Aubron C,Bailey M,Bellomo R,Pilcher D,Cheng AC,Hegarty C,Reade MC,McQuilten Z

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Though a number of studies have elegantly characterized platelet activation during storage, less attention has been paid to the initial activation caused by different collection procedures. STUDY DESIGN AND METHODS:The effects of two blood cell separators on the initial activation of platelets were measured...

journal_title：Transfusion

authors： Stohlawetz P,Hergovich N,Stiegler G,Eichler HG,Höcker P,Kapiotis S,Jilma B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Novel gel centrifugation test (GCT) cards were evaluated with respect to their ability to estimate the quantity of IgG on RBCs and the determination of the IgG subclasses IgG1 and IgG3. STUDY DESIGN AND METHODS:In 65 patients with a positive DAT, the amount of IgG-gamma-, IgG1, and IgG3 on RBCs was examined...

journal_title：Transfusion

authors： Lynen R,Krone O,Legler TJ,Köhler M,Mayr WR

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

journal_title：Transfusion

authors： Borkent-Raven BA,Janssen MP,Van Der Poel CL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Although the risk of transmitting infectious agents by blood transfusion is dramatically reduced after donor selection, leukoreduction, and laboratory testing, some could still be present in donor's blood. A description of metagenomes in blood products eligible for transfusion represents relevant information...

journal_title：Transfusion

authors： Lau P,Cordey S,Brito F,Tirefort D,Petty TJ,Turin L,Guichebaron A,Docquier M,Zdobnov EM,Waldvogel-Abramowski S,Lecompte T,Kaiser L,Preynat-Seauve O

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Collections and transfusions of blood in the United States in 1994 were measured and compared with those in 1992. STUDY DESIGN AND METHODS:Completed survey questionnaires were returned by all 147 regional blood centers, 1340 American Association of Blood Banks (AABB) member hospitals, and 523 non-AABB hospi...

journal_title：Transfusion

authors： Wallace EL,Churchill WH,Surgenor DM,Cho GS,McGurk S

更新日期：1998-07-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The Am phenotype has been characterized as a weak expression of the A antigen on red blood cells but the presence of a normal quantity of the A antigen in saliva. This study describes a molecular genetic analysis of members of an Am family. STUDY DESIGN AND METHODS:The eight exon regions of the ABO genes of...

journal_title：Transfusion

authors： Lin M,Hou MJ,Twu YC,Yu LC

更新日期：2005-01-01 00:00:00

abstract：:A stable mouse hybridoma line secreting monoclonal anti-C3d antibody (NBTS/BRIC 8) was produced. Ascitic fluid containing BRIC 8 can be used at a final dilution of 1 to 5000 to provide an excellent antiglobulin reagent when mixed with a conventional polyclonal rabbit anti-human IgG serum. ...

journal_title：Transfusion

authors： Holt PD,Donaldson C,Judson PA,Johnson P,Parsons SF,Anstee DJ

更新日期：1985-05-01 00:00:00

abstract：:Using a recently developed enzyme-linked immunosorbent assay, gene dosage effects were demonstrated for the Duffy, Ss, and Rh red blood cell antigen systems. We report a comparison by an antibody-binding assay of the relative amounts of Fya and Fyb antigens on FyaFya, FyaFyb, FybFyb, FyaFyx, and FyxFyx erthrocytes, an...

journal_title：Transfusion

authors： Caren LD,Bellavance R,Grumet FC

更新日期：1982-11-01 00:00:00