Guidelines for blood utilization review.

abstract：BACKGROUND:Studies have demonstrated that immunity against platelet (PLT) transfusions is dependent on recipient antigen-presenting cells (APCs) and their ability to produce nitric oxide (NO). To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO(-)) and its ability to affect PLT immunity. S...

journal_title：Transfusion

authors： Semple JW,Speck ER,Fabron A Jr,Kim RA,Freedman J

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The aim of this study was to assess the sensitivity and specificity of a n...

journal_title：Transfusion

authors： Chang CD,Cheng KY,Jiang LX,Salbilla VA,Haller AS,Yem AW,Bryant JD,Kirchhoff LV,Leiby DA,Schochetman G,Shah DO

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The NOD/SCID mouse is a widely used model for human cord blood (CB) transplantation. Engraftment is generally estimated with semiquantitative methods, measuring the percentage of human cells among mouse cells. To compare protocols aiming to improve hematopoietic recovery, quantitative methods to enumerate hu...

journal_title：Transfusion

authors： Schipper LF,van Hensbergen Y,Fibbe WE,Brand A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:All published reports have described methods for virus photoinactivation which significantly alter red cell (RBC) properties during storage. In order to improve virucidal activity and reduce damage to RBCs, a series of phenothiazine derivatives were either synthesized or purified and screened for bacteriopha...

journal_title：Transfusion

authors： Wagner SJ,Skripchenko A,Robinette D,Mallory DA,Cincotta L

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Transfusion safety rests heavily on the health of blood donors. Although they are perceived as being healthier than average, little is known about their long-term disease patterns and to which extent the blood banks' continuous efforts to optimize donor selection has resulted in improvements. Mortality and c...

journal_title：Transfusion

authors： Edgren G,Tran TN,Hjalgrim H,Rostgaard K,Shanwell A,Titlestad K,Wikman A,Norda R,Jersild C,Wideroff L,Gridley G,Adami J,Melbye M,Nyrén O,Reilly M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:A novel nonenveloped single-stranded circular DNA virus (TTV) was recently identified. The prevalence of TTV in blood donors in the United States is, however, still unclear. STUDY DESIGN AND METHODS:Viral DNA was detected in US blood donors from five cities by using two sets of TTV primers: NG059/NG061/NG06...

journal_title：Transfusion

authors： Handa A,Dickstein B,Young NS,Brown KE

更新日期：2000-02-01 00:00:00

abstract：:In spite of growing awareness of the potential risks associated with transfusion, the number of platelet units transfused in the United States continues to increase each year. There is a growing interest in ensuring that all transfusions are administered for appropriate reasons. Prospective review of requests for tran...

journal_title：Transfusion

authors： Sielaff BH,Scott EP,Connelly DP

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Ultrasound-facilitated delivery of topical anesthetics has been used to achieve effective anesthesia within 5 minutes for venipuncture and the insertion of intravenous access devices, but has never been studied for blood donation. STUDY DESIGN AND METHODS:This study was a single-center, prospective, randomi...

journal_title：Transfusion

authors： Stowell CP,Trieu MQ,Chuang H,Katz N,Quarrington C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The ABO system is of fundamental importance in the fields of transfusion and transplantation and has apparent associations with certain diseases, including cardiovascular disorders. ABO expression is reduced in the late phase of erythroid differentiation in vitro, whereas histone deacetylase inhibitors (HDAC...

journal_title：Transfusion

authors： Takahashi Y,Kubo R,Sano R,Nakajima T,Takahashi K,Kobayashi M,Handa H,Tsukada J,Kominato Y

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Although the standard classification system for acute transfusion reactions adequately describes the general features associated with the various types of reactions, it was not designed to provide strict criteria for diagnosis and classification. Consequently, its use to classify individual reactions can res...

journal_title：Transfusion

authors： Sanders RP,Geiger TL,Heddle N,Pui CH,Howard SC

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) can be used as hematopoietic stem cell source for transplantation. The success of a transplantation is highly correlated with the number of total nucleated cells (TNCs) and CD34+ cells in the UCB. Certain obstetric factors increase the yield of stem cells in the UCB. It is necessar...

journal_title：Transfusion

authors： Manegold G,Meyer-Monard S,Tichelli A,Pauli D,Holzgreve W,Troeger C

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Transfusion-induced serum sickness reactions are rarely reported in the literature. The Type III hypersensitivity reaction to heterologous proteins involves deposition of complement and immune complexes in small vessel walls resulting in a leukocytoclastic vasculitis. A case of a multiply transfused patient ...

journal_title：Transfusion

authors： Saegeman V,Wynendaele W,Kerre S,Dedeurwaerdere F,Van den Driessche M,Moerman J

更新日期：2009-02-01 00:00:00

abstract：:Currently, platelet concentrates are stored in 50 to 60 ml of plasma. A major drawback to storage in plasma is the considerable loss of platelet function which occurs during storage. A modified Tyrodes medium has been developed for storage of platelets. A comparison between platelet concentrates stored in this medium ...

journal_title：Transfusion

authors： Rock G,Swenson SD,Adams GA

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:A total of 517,072 and 399,326 consecutive donations were screened for hepatitis B virus (HBV) by individual-donation nucleic acid testing (ID-NAT) using Ultrio and Ultrio Plus assays (Novartis Diagnostics), respectively. The impact of more sensitive HBV detection by the latter assay version was established ...

journal_title：Transfusion

authors： Tsoi WC,Lelie N,Lin CK

更新日期：2013-10-01 00:00:00

abstract：:To determine whether chloroquine can specifically elute HLA antigens and beta 2-microglobulin (beta 2-M) from the platelet surface, quantitative immunofluorescence flow cytometry and monoclonal antibodies were used to show that HLA antigens and beta 2-M were proportionally eluted from the platelet surface without affe...

journal_title：Transfusion

authors： Kao KJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Exposure to blood products during pregnancy carries a potential risk of transfusion transmission of infectious agents. Blood agencies have historically sought optimal deferral and testing strategies to protect blood supplies in part to ensure the protection of pregnant women and their unborn infants. The Zik...

journal_title：Transfusion

authors： Murphy MS,Shehata N,Colas JA,Chassé M,Fergusson DA,O'Brien SF,Goldman M,Tinmouth A,Forster AJ,Wilson K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...

journal_title：Transfusion

authors： Assal A,Barlet V,Deschaseaux M,Dupont I,Gallian P,Guitton C,Morel P,David B,De Micco P

更新日期：2009-02-01 00:00:00

abstract：:Extracellular vesicles (EVs) are small, subcellular vesicles that are released from a variety of cells and play important roles in cell-to-cell communication. Transfused blood products, including red blood cell, platelet, and plasma products contain EVs that are capable of interacting with and altering immune cell fun...

journal_title：Transfusion

authors： Menocha S,Muszynski JA

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Blood transfusion has been cited as one of the five most overutilized therapeutic procedures in the United States. We assessed the impact of clinical decision support at computerized physician order entry and education on red blood cell (RBC) transfusions and clinical patient outcomes at our institution. ST...

journal_title：Transfusion

authors： Goodnough LT,Maggio P,Hadhazy E,Shieh L,Hernandez-Boussard T,Khari P,Shah N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

journal_title：Transfusion

authors： Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Bacterial contamination or platelet (PLT) metabolism can change the pH of stored PLT concentrates (PCs). Measurement of pH for quality control is currently done on a limited basis. An easy noninvasive method was developed to obtain sequential pH measurements over time, without risking contamination and/or co...

journal_title：Transfusion

authors： Barker LM,Nanassy OZ,Reed MW,Geelhood SJ,Pfalzgraf RD,Cangelosi GA,De Korte D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Pulmonary transfusion reactions are important complications of blood transfusion, yet differentiating these clinical syndromes is diagnostically challenging. We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lu...

journal_title：Transfusion

authors： Roubinian NH,Looney MR,Kor DJ,Lowell CA,Gajic O,Hubmayr RD,Gropper MA,Koenigsberg M,Wilson GA,Matthay MA,Toy P,Murphy EL,TRALI Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:A reliable, validated method for rapidly determining HPC viability is essential for clinical cell engineering. STUDY DESIGN AND METHODS:A fluorometric cell viability assay using acridine orange and propidium iodide (AO/PI) was compared to the current standard, trypan blue (TB) exclusion. Viable cells staine...

journal_title：Transfusion

authors： Mascotti K,McCullough J,Burger SR

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Standard plateletpheresis techniques and effects on platelet (PLT) donors were investigated to provide an informative basis for advancement of apheresis software. STUDY DESIGN AND METHODS:Three paired groups with 33 male and 22 female blood donors were prospectively investigated by analyzing blood counts of...

journal_title：Transfusion

authors： Strasser EF,Schuster M,Egler K,Bauer J,Weisbach V,Ringwald J,Zimmermann R,Zingsem J,Eckstein R

更新日期：2005-05-01 00:00:00

abstract：:Platelet concentrates intended for transfusion to immunosuppressed patients are irradiated to minimize transfusion-induced graft-versus-host disease. Because few reports describe how irradiation influences stored platelets, the authors studied whether 5000 rad of gamma irradiation, the maximum dose currently used clin...

journal_title：Transfusion

authors： Moroff G,George VM,Siegl AM,Luban NL

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Hyperhemolysis syndrome (HS) has been well described both in sickle cell disease (SCD) and non-SCD patients. The pathogenesis remains unclear. The possible mechanisms include bystander hemolysis, suppression of erythropoiesis, and destruction of red cells (RBCs) due to contact lysis via activated macrophages...

journal_title：Transfusion

authors： Win N,New H,Lee E,de la Fuente J

更新日期：2008-06-01 00:00:00

abstract：:ADAMTS13 is an enzyme that acts by cleaving prothrombotic von Willebrand factor (VWF) multimers from the vasculature in a highly regulated manner. In pathologic states such as thrombotic thrombocytopenic purpura (TTP) and other thrombotic microangiopathies (TMAs), VWF can bind to the endothelium and form large multime...

journal_title：Transfusion

authors： Plautz WE,Raval JS,Dyer MR,Rollins-Raval MA,Zuckerbraun BS,Neal MD

更新日期：2018-10-01 00:00:00