Histone deacetylase inhibitors suppress ABO transcription in vitro, leading to reduced expression of the antigens.

abstract：BACKGROUND:Effective donor skin disinfection is essential in preventing bacterial contamination of blood components with skin flora bacteria like Staphylococcus epidermidis. Cell aggregates of S. epidermidis (biofilms) are found on the skin and are resistant to the commonly used donor skin disinfectants chlorhexidine-g...

journal_title：Transfusion

authors： Alabdullatif M,Boujezza I,Mekni M,Taha M,Kumaran D,Yi QL,Landoulsi A,Ramirez-Arcos S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Novel gel centrifugation test (GCT) cards were evaluated with respect to their ability to estimate the quantity of IgG on RBCs and the determination of the IgG subclasses IgG1 and IgG3. STUDY DESIGN AND METHODS:In 65 patients with a positive DAT, the amount of IgG-gamma-, IgG1, and IgG3 on RBCs was examined...

journal_title：Transfusion

authors： Lynen R,Krone O,Legler TJ,Köhler M,Mayr WR

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The aim of this study was to assess the sensitivity and specificity of a n...

journal_title：Transfusion

authors： Chang CD,Cheng KY,Jiang LX,Salbilla VA,Haller AS,Yem AW,Bryant JD,Kirchhoff LV,Leiby DA,Schochetman G,Shah DO

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Marrow stromal cells (MSCs) for clinical trials are inevitably stored before administration, but little is known about the effects of storage on MSCs. The effects of short-term liquid storage on the in vitro function of MSCs intended for a clinical trial were studied. STUDY DESIGN AND METHODS:Early-passage ...

journal_title：Transfusion

authors： Lane TA,Garls D,Mackintosh E,Kohli S,Cramer SC

更新日期：2009-07-01 00:00:00

abstract：:The development of a synthetic medium for platelet storage is an important goal in transfusion medicine. Its use would make large volumes of plasma available for fractionation and might improve the quality of platelets after storage. Several investigators have described successful storage in media containing acetate. ...

journal_title：Transfusion

authors： Shimizu T,Murphy S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The Am phenotype has been characterized as a weak expression of the A antigen on red blood cells but the presence of a normal quantity of the A antigen in saliva. This study describes a molecular genetic analysis of members of an Am family. STUDY DESIGN AND METHODS:The eight exon regions of the ABO genes of...

journal_title：Transfusion

authors： Lin M,Hou MJ,Twu YC,Yu LC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:In cases of massive hemorrhage in the US military, improved outcomes have been reported with the use of warm, fresh whole blood transfusions. Cold-stored low-titer type O whole blood (LTOWB) has become the preferred product for resuscitation of severe bleeding in deployed surgical units. Reports of LTOWB use...

journal_title：Transfusion

authors： Bahr TM,DuPont TL,Morris DS,Pierson SE,Esplin MS,Brown SM,O'Brien EA,Ilstrup SJ,Christensen RD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Tests for platelet-specific antibodies are important in the diagnosis of immune platelet disorders. Monoclonal antibody glycoprotein capture assays have been the gold standards in platelet antibody detection for almost 30 years. However, such assays are complex and cumbersome to perform, which limits their r...

journal_title：Transfusion

authors： Metzner K,Bauer J,Ponzi H,Ujcich A,Curtis BR

更新日期：2017-07-01 00:00:00

abstract：:Anti-D sensitized red cells were converted to stroma, either by digitonin or hypotonic lysis, and eluates prepared by the modified rapid acid-stromal method. SDS-PAGE and both rocket- and crossed-immunoelectrophoresis showed that, of the total protein content of the eluates, 11 to 25 percent was IgG, 18 to 45 percent ...

journal_title：Transfusion

authors： Rearden A,Chiu P,Elmajian D

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Platelets for transfusion become senescent and dysfunctional during storage, resulting in a markedly short shelf life (5 days). We hypothesized that oxidative stress might account for this decline. STUDY DESIGN AND METHODS:Human platelets were treated with or without antioxidants before storage, and samples...

journal_title：Transfusion

authors： Wang L,Xie R,Fan Z,Yang J,Liang W,Wu Q,Wu MX,Wang Z,Lu Y

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Collections and transfusions of blood in the United States in 1994 were measured and compared with those in 1992. STUDY DESIGN AND METHODS:Completed survey questionnaires were returned by all 147 regional blood centers, 1340 American Association of Blood Banks (AABB) member hospitals, and 523 non-AABB hospi...

journal_title：Transfusion

authors： Wallace EL,Churchill WH,Surgenor DM,Cho GS,McGurk S

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Jra is a high-frequency antigen seen in all populations, but the clinical significance of Jra antibodies is incompletely understood. Two cases are reported in which patients with anti-Jra received incompatible transfusions. CASE REPORTS:A 69-year-old Japanese man had anti-K and anti-Jra. Despite multiple tr...

journal_title：Transfusion

authors： Kwon MY,Su L,Arndt PA,Garratty G,Blackall DP

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:There is little knowledge how different hold times of hyperconcentrated platelet (PLT) suspensions (HPSs) before the addition of platelet additive solution (PAS) might affect PLT quality. We compared the in vitro quality of single-donor PLT concentrates (SDPs) with immediate or delayed PAS addition and studi...

journal_title：Transfusion

authors： Ringwald J,Tully S,Geier C,Hauck B,Weiss D,Callaert M,Eckstein R

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The residual blood left in the placenta, previously considered a biologic waste, contains sufficient hematopoietic stem and progenitor cells to consistently engraft at least a small recipient. Over the past several years, more than 500 HLA-matched, related and unrelated, allogeneic cord blood transplants hav...

journal_title：Transfusion

authors： Reems JA,Fujita D,Tyler T,Moldwin R,Smith SD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:An HIV-1 and HCV NAT blood screening assay (Procleix HIV-1/HCV, Gen-Probe, Inc.) simultaneously detecting HIV-1 and HCV RNA) has been implemented. Donor plasma samples reactive in the Procleix HIV-1/HCV assay are tested with the HIV-1 and HCV discriminatory assays to resolve whether HIV-1 RNA, HCV RNA, or bo...

journal_title：Transfusion

authors： Vargo J,Smith K,Knott C,Wang S,Fang C,McDonough S,Giachetti C,Caglioti S,Gammon R,Gilbert D,Jackson JB,Richards W,Stramer S,Mimms L

更新日期：2002-07-01 00:00:00

abstract：:The selection of platelet donors, according to HLA antigens, has been computerized using a method based on the calculation of incompatibilities and risk of immunization between donors and recipients. Since the risk that an antigen present in a donor will immunize an incompatible recipient of known HLA phenotype, an in...

journal_title：Transfusion

authors： Muller JY,Cartron JP,Trillot P,Halle L,Roquin H

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:DNA testing has enabled the documenting of numerous variants of RHCE alleles, especially in individuals of African origin. The risk for production of clinically significant alloantibodies to Rh antigens of patients carrying variant RHCE alleles has led us to analyze the different RhCE variants investigated b...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Juszczak G,Beolet M,Deram G,Martin-Blanc S,Dubeaux I,Roussel M,Kappler-Gratias S,Gien D,Poupel S,Rouger P,Le Pennec PY

更新日期：2011-06-01 00:00:00

abstract：:Ultraviolet B (UVB) irradiation of platelet concentrates (PCs) may prevent the development of posttransfusion HLA alloimmunization. As irradiation performed in a blood center or a hospital will probably be associated with a variable postirradiation delay before transfusion, the ability to store PCs after UVB irradiati...

journal_title：Transfusion

authors： Snyder EL,Beardsley DS,Smith BR,Horne W,Johnson R,Wooten T,Napychank PA,Male P,Buchholz DH

更新日期：1991-07-01 00:00:00

abstract：:Four commercial test kits for detecting cytomegalovirus (CMV) antibodies (indirect hemagglutination assay, indirect fluorescent antibody technique, enzyme immunoassay, and passive latex agglutination technique) were compared according to their technical demand, hands-on time, turnaround time, concordance with other te...

journal_title：Transfusion

authors： Feng CS,Williams IB,Gohd RS,Causey AP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

journal_title：Transfusion

authors： Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Invariant natural killer T cells (iNKT cells) may suppress graft-versus-host disease (GVHD) after allogeneic transplantation. The purpose of this study was to investigate the therapeutic potential of iNKT cells from major histocompatibility complex (MHC)-mismatched donors for preventing GVHD after allogeneic...

journal_title：Transfusion

authors： Yang J,Gao L,Liu Y,Ren Y,Xie R,Fan H,Qian K

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Since their description in the 1970s, anti-Hr(B) (antibody against a high-prevalence Rh antigen) and anti-hr(B) (anti-e-like antibody) are still a subject of debate about representing two aspects of a global immune response or being two independent antibodies. STUDY DESIGN AND METHODS:The aim of this study ...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Tourret S,Beolet M,Many H,Juszczak G,Roussel M,Kappler-Gratias S,Rouger P,Le Pennec PY

更新日期：2009-11-01 00:00:00

abstract：:A 24-year-old, blood-group O Polynesian woman with multiple red blood cell antibodies received a group A, HLA-compatible, sex-matched bone marrow transplantation as treatment for severe aplastic anemia. High retransplantation titers of ABO isohemagglutinins were successfully reduced by repeated plasmaphereses. Despite...

journal_title：Transfusion

authors： Ockelford PA,Hill RS,Nelson L,Blacklock HA,Woodfield DG,Matthews JR

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Our blood bank is part of a large academic institution with an active sickle cell anemia program. We provide sickle patients with blood phenotypically matched for C/c, E/e, and K antigens. Since licensed reagents are available for phenotyping C/c, E/e, and K on an automated blood analyzer, we decided to eval...

journal_title：Transfusion

authors： Le N,Harach ME,Kay JK,Brown RP,Everetts JN,Herman JH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Human infections with simian foamy viruses (SFVs) have been reported after occupational and nonoccupational exposure to infected animals and their tissues, blood, and body fluids, although there is no evidence for human-to-human transmission. We previously demonstrated SFV transmission in monkeys by blood tr...

journal_title：Transfusion

authors： Williams DK,Khan AS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Recently, a more accurate and reliable screening test has been investigated for noninvasive prenatal fetal RHD genotyping from D- women. The objective of this study was to perform the new method of noninvasive fetal RHD genotyping with maternal plasma from D- women by use of capillary electrophoresis. STUDY...

journal_title：Transfusion

authors： Kimura M,Sato C,Hara M,Ishihara O,Ikebuchi K

更新日期：2008-06-01 00:00:00

abstract：:We report a case of "naturally-occurring" (nonred blood cell stimulated) anti-K1. The patient had never received a blood transfusion. Red blood cell antibody screening panels showed agglutination with K:1 red blood cells at room temperature and not in the anti-globulin test. Testing with 2-mercaptoethanol showed the a...

journal_title：Transfusion

authors： Kanel GC,Davis I,Bowman JE

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00