Packed blood cells stored in AS-5 become proinflammatory during storage.

abstract：BACKGROUND:The survival of fresh and preserved platelets has been used primarily to determine their therapeutic effectiveness. The function of the fresh and preserved platelets has been difficult to assess. In stable thrombocytopenic patients, platelet function of fresh and preserved allogeneic platelets is evaluated b...

journal_title：Transfusion

authors： Valeri CR,MacGregor H,Giorgio A,Ragno G

更新日期：2002-09-01 00:00:00

abstract：:Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

journal_title：Transfusion

authors： Maegele M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The rare Bombay phenotype is usually due to a primary genetic defect in an alpha-2- or alpha-4-fucosyltransferase. The present study was done to investigate a patient with normal transferases, who exhibits the Bombay phenotype. CASE REPORT:Red cells of the patient, his parents, and siblings were phenotyped ...

journal_title：Transfusion

authors： Shechter Y,Etzioni A,Levene C,Greenwell P

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...

journal_title：Transfusion

authors： Wu CG,Mason B,Jong J,Erdman D,McKernan L,Oakley M,Soucie M,Evatt B,Yu MY

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

journal_title：Transfusion

authors： Rios J,Westra J,Dy B,Young PP

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusion is the primary treatment for thrombocytopenia. PLTs are obtained exclusively from volunteer donors, and the PLT product has only a 5-day shelf life, which can limit supply and result in PLT shortages. PLTs derived from stem cells could help to fill this clinical need. However, curr...

journal_title：Transfusion

authors： Avanzi MP,Oluwadara OE,Cushing MM,Mitchell ML,Fischer S,Mitchell WB

更新日期：2016-01-01 00:00:00

abstract：:This study was designed to test the viability of two multiple request techniques of behavioral influence for recruiting blood donors by telephone. The first technique utilizes a small antecedent request to encourage behavioral involvement and favorable disposition toward the target activity of the critical request to ...

journal_title：Transfusion

authors： Hayes TJ,Dwyer FR,Greenwalt TJ,Coe NA

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:In the Rh blood group system, variant RhD and RhCE express several partial antigens. We investigated RH in samples with partial DIVa that demonstrated weak and variable reactivity with anti-C. STUDY DESIGN AND METHODS:Standard hemagglutination techniques, polymerase chain reaction-based assays, and RH seque...

journal_title：Transfusion

authors： Westhoff CM,Vege S,Halter Hipsky C,Hue-Roye K,Copeland T,Velliquette RW,Horn T,Lomas-Francis C,Reid ME

更新日期：2013-04-01 00:00:00

abstract：:In therapeutic plasmapheresis, patient plasma is withdrawn and a colloid replacement solution is infused in its place. A 4% to 5% human serum albumin solution in saline is the preferred replacement solution in most instances, even though this practice causes transient mild deficiencies of most plasma proteins. Albumin...

journal_title：Transfusion

authors： McLeod BC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units (CBUs) were electively stored in private CB banks. Unlike public banks, which utilize specific criteria...

journal_title：Transfusion

authors： Sun J,Allison J,McLaughlin C,Sledge L,Waters-Pick B,Wease S,Kurtzberg J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Thrombocytopenia is a serious side effect following high-dose chemotherapy or whole-body irradiation. For many patients, a hematopoietic stem cell (HSC) transplant is required as part of the treatment or to restore the integrity of the hematopoietic system. In this article, we first review the origin of thro...

journal_title：Transfusion

authors： Pineault N,Boyer L

更新日期：2011-11-01 00:00:00

abstract：:A prospective study of newborn infants who required exchange transfusion was undertaken to evaluate the risk of transmission of cytomegalovirus (CMV). Buffy coat-, urine- and saliva-saturated throat swabs for viral cultures and serum specimens for CMV complement-fixing (CF) antibody were obtained from 45 infant-mother...

journal_title：Transfusion

authors： Kumar A,Nankervis GA,Cooper AR,Gold E,Kumar ML

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:In the pandemic, testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time polymerase chain reaction is one of the pillars on which countermeasures are based. Factors limiting the output of laboratories interfere with the effectiveness of public health measures. Conserving reagent...

journal_title：Transfusion

authors： Schmidt M,Hoehl S,Berger A,Zeichhardt H,Hourfar K,Ciesek S,Seifried E

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:Transfusion of the incorrect blood component is a frequent serious incident associated with transfusion and often involves misidentification of the patient and/or the unit of blood. The objective of this study was to assess the effect of a simple intervention designed to improve performance of the bedside ch...

journal_title：Transfusion

authors： Murphy MF,Casbard AC,Ballard S,Shulman IA,Heddle N,Aubuchon JP,Wendel S,Thomson A,Hervig T,Downes K,Carey PM,Dzik WH,BEST Research Collaborative.

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Radiation and filtration have achieved satisfactory results in inactivation or removal of tumor cells mixed in salvage blood, but some drawbacks remain. This study evaluated the inactivation on HCT116 cells mixed in simulative salvage blood by riboflavin photochemical treatment. METHODS:HCT116 cells were ad...

journal_title：Transfusion

authors： Yu Y,Yang L,He C,Tai S,Ma C,Yang T,Wang D

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Blood collection centers are charged with creating donor educational materials (DnEM) that are easily understood across all prospective donor populations, while addressing mandates and recommendations from regulatory agencies and professional standard setting organizations. Donors must have sufficient inform...

journal_title：Transfusion

authors： Wehrli G,Rossmann SN,Waxman DA,Katz LM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Proteomics methods may be used to analyze changes occurring in stored blood products. These data sets can identify processes leading to storage-associated losses of blood component quality such as the platelet (PLT) storage lesion (PSL). The optimal strategy to perform such analyses to obtain the most inform...

journal_title：Transfusion

authors： Thon JN,Schubert P,Duguay M,Serrano K,Lin S,Kast J,Devine DV

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Blood components are often given prophylactically before the placement of invasive lines in patients with coagulation defects. Little, however, is known about the epidemiology of defects in these patients. The purpose of this study is to ascertain what proportion of intensive care patients who receive invasi...

journal_title：Transfusion

authors： DeLoughery TG,Liebler JM,Simonds V,Goodnight SH

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The von Willebrand factor (VWF)-cleaving protease, ADAMTS13, is often deficient in cases of thrombotic thrombocytopenic purpura (TTP). The primary treatment of TTP is therapeutic plasma exchange (TPE) utilizing a variety of plasma products that help restore ADAMTS13 activity. However, multiple replacement pr...

journal_title：Transfusion

authors： Scott EA,Puca KE,Pietz BC,Duchateau BK,Friedman KD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Recent genome-wide association studies in Caucasians suggested that an association exists between the ABO gene locus and soluble levels of P-selectin (sP-selectin). However, it is unclear if the relationship corresponds to the phenotypic expression of ABO groups or is present in different ethnic groups. The ...

journal_title：Transfusion

authors： Chen Y,Zhuo X,Lin Y,Huang W,Xiao J,Zeng J,Jiang L,Chen C,Lin H,Dettke M

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Critically bleeding trauma patients require coordinated and efficient decision-making processes to ensure optimal management of their massive transfusion (MT) requirements. Human factors (HFs) is a discipline that investigates factors influencing work processes from the organizational, group, and individual ...

journal_title：Transfusion

authors： Enticott JC,Jeffcott S,Ibrahim JE,Wood EM,Cole-Sinclair M,Fitzgerald M,Cameron PA,Phillips LE

更新日期：2012-12-01 00:00:00

abstract：:Bone marrow was harvested for the purpose of autologous bone marrow transplantation (ABMT) in 21 patients previously treated with chemotherapy and in complete remission from acute leukemia or non-Hodgkin's lymphoma. The volume required to obtain 2 x 10(8) nucleated cells per kg was less than 15 mL per kg in 13 patient...

journal_title：Transfusion

authors： Sonneveld P,de Leeuw CA,Schipperus M,Lindemans J,Abels J

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Borrelia miyamotoi, a recently discovered relapsing fever spirochete, occurs in hard-bodied ticks wherever Lyme disease is endemic. Human infection is associated with relapsing fever and can cause meningoencephalitis in immunocompromised patients. A few cases of transfusion transmission of other relapsing fe...

journal_title：Transfusion

authors： Krause PJ,Hendrickson JE,Steeves TK,Fish D

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron stores expressed as fe...

journal_title：Transfusion

authors： Rigas AS,Berkfors AA,Pedersen OB,Sørensen E,Nielsen KR,Larsen MH,Paarup HM,Wandall HH,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Patients with severe combined immunodeficiency (SCID) treated with allogeneic bone marrow transplantation often receive a milder conditioning regimen than patients who undergo transplantation for hematologic malignancy, and they regularly retain circulating white cells of host origin. The origin of circulati...

journal_title：Transfusion

authors： Brady KA,Cowan MJ,Leavitt AD

更新日期：1996-04-01 00:00:00

abstract：:Social and economic development, along with increased health care coverage, has caused a sharp increase in the clinical demand for blood in China. Whole blood collection has increased rapidly in the past decade but has failed to keep pace with the ever-increasing demand. Overall, the country's blood safety has been im...

journal_title：Transfusion

authors： Shi L,Wang JX,Stevens L,Ness P,Shan H

更新日期：2014-02-01 00:00:00

abstract：:We describe a nonanaphylactic hemoglobinuric reaction caused by transfusion of frozen red cells, deglycerolyzed by standard technique, obtained from a donor with undiagnosed sickle trait. Although significant hemoglobinemia and hemoglobinuria were noted, the recipient experienced no adverse clinical reactions. The ben...

journal_title：Transfusion

authors： Kelleher JF Jr,Luban NL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Congenital thrombotic thrombocytopenic purpura (TTP) may not be recognized until organ failure related to the microvascular thrombosis occurs. Kidney failure may be the initial presenting clinical feature. Kidney transplantation has been contraindicated because of the assumption that the continuing microvasc...

journal_title：Transfusion

authors： Fattah H,Kumar D,George JN,Massey HD,King AL,Friedman KD,Gupta G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Pigs are a potential source of red blood cells (RBCs) for transfusion into humans, but the presence of galactose-alpha1,3-galactose (Gal) epitopes on their surface, against which humans have anti-Gal, has been perceived as a major barrier. alpha1,3-Galactosyltransferase gene-knockout pigs, which do not expre...

journal_title：Transfusion

authors： Rouhani FJ,Dor FJ,Cooper DK

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Recombinant activated factor VII (rFVIIa) is being tested to improve hemostasis in a variety of bleeding disorders. Clinical indications and efficacy are still being evaluated for this product. CASE REPORT:Over a 17-month period, rFVIIa was used to treat central nervous system hemorrhage in three patients w...

journal_title：Transfusion

authors： Huang WY,Kruskall MS,Bauer KA,Uhl L,Shaz BH

更新日期：2004-11-01 00:00:00