Duration of platelet storage and outcomes of critically ill patients.

abstract：BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

journal_title：Transfusion

authors： Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Since their description in the 1970s, anti-Hr(B) (antibody against a high-prevalence Rh antigen) and anti-hr(B) (anti-e-like antibody) are still a subject of debate about representing two aspects of a global immune response or being two independent antibodies. STUDY DESIGN AND METHODS:The aim of this study ...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Tourret S,Beolet M,Many H,Juszczak G,Roussel M,Kappler-Gratias S,Rouger P,Le Pennec PY

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Chronic transfusion in sickle cell disease (SCD) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. The aim of our study was to assess the safety and efficacy of automated red blood cell exchange (aRBX) in patients with SCD pre...

journal_title：Transfusion

authors： Dedeken L,Lê PQ,Rozen L,El Kenz H,Huybrechts S,Devalck C,Diallo S,Heijmans C,Ferster A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia major require iron chelation therapy (ICT) to prevent complications from transfusional iron overload. Deferoxamine is effective, but requires administration as a slow continuous subcutaneous or intravenous infusion five to seven times per week. Deferiprone is a three-times-daily ora...

journal_title：Transfusion

authors： Delea TE,Edelsberg J,Sofrygin O,Thomas SK,Baladi JF,Phatak PD,Coates TD

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies have been shown to be effective in decreasing red blood cell (RBC) utilization in specific patient groups. However, few data exist describing the extent of RBC transfusion reduction or their impact on transfusion practice and mortality in a diverse inpatient population. STUDY D...

journal_title：Transfusion

authors： Roubinian NH,Escobar GJ,Liu V,Swain BE,Gardner MN,Kipnis P,Triulzi DJ,Gottschall JL,Wu Y,Carson JL,Kleinman SH,Murphy EL,NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Transfusion-transmitted babesiosis (TTB) has been rapidly increasing in incidence since the beginning of the 21st century. Asymptomatic individuals with Babesia infection are able to donate blood in the United States because of the lack of specific blood donation testing. Blood products collected in Babesia-...

journal_title：Transfusion

authors： LeBel DP 2nd,Moritz ED,O'Brien JJ,Lazarchick J,Tormos LM,Duong A,Fontaine MJ,Squires JE,Stramer SL

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Guidelines for red blood cell (RBC) transfusions exist; however, transfusion practices vary among centers. This study aimed to analyze transfusion practices and the impact of patients and institutional characteristics on the indications of RBC transfusions in preterm infants. STUDY DESIGN AND METHODS:RBC tr...

journal_title：Transfusion

authors： dos Santos AM,Guinsburg R,Procianoy RS,Sadeck Ldos S,Netto AA,Rugolo LM,Luz JH,Bomfim O,Martinez FE,de Almeida MF,Brazilian Network on Neonatal Research.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units (CBUs) were electively stored in private CB banks. Unlike public banks, which utilize specific criteria...

journal_title：Transfusion

authors： Sun J,Allison J,McLaughlin C,Sledge L,Waters-Pick B,Wease S,Kurtzberg J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Tranexamic acid (TXA) has been reported to demonstrate efficacy in reducing blood loss during arthroplasty procedures. STUDY DESIGN AND METHODS:This study examines the effectiveness of TXA as a central element of a patient blood management program (PBMP) by evaluating blood loss and transfusion of red blood...

journal_title：Transfusion

authors： Pitta M,Zawadsky M,Verstraete R,Rubinstein A

更新日期：2016-02-01 00:00:00

abstract：:Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

journal_title：Transfusion

authors： Maegele M

更新日期：2013-01-01 00:00:00

abstract：:Since the first issue of TRANSFUSION in 1961, there has been a tremendous expansion in not only the number of blood group antigens identified but also in our knowledge of their biochemical basis, function, and more recently, associated DNA changes. As certain techniques became available, our ability to discover and el...

journal_title：Transfusion

authors： Daniels G,Reid ME

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Deferasirox (DFRA) is a new approved oral iron chelator. Its advantages are that it is convenient and better tolerated and adhered to due to "once-daily" oral dosage. However, its use in the field is limited and it is yet to be subjected to postmarketing surveillance. CASE REPORT:A 18.75-year-old male with ...

journal_title：Transfusion

authors： Wei HY,Yang CP,Cheng CH,Lo FS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:G-CSF-mobilized whole blood (WB) is a cost-reducing and simple alternative for peripheral blood progenitor cell transplantation. Recently, it was demonstrated that mobilized WB supplemented with Leibovitz's L15 medium permitted prolonged preservation of clonogenic cells at ambient temperature. In this study,...

journal_title：Transfusion

authors： de Kreuk AM,Jonkhoff AR,Zevenbergen A,Wilhelm AJ,van Oostveen JW,Schuurhuis GJ,Huijgens PC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Growth in size and complexity of clinical hematopoietic progenitor cell (HPC) transplant programs necessitates parallel increases in cellular therapy laboratory (CTL) workload. Typically individually developed, HPC product processing is labor and time intensive. Variation in procedure type and numbers across...

journal_title：Transfusion

authors： Thibodeaux SR,McKenna DH,Szczepiorkowski ZM,Fontaine MJ,Kelley L,Reems JA,Young PP,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Development of de novo alloantibodies against recipient's red blood cell (RBC) antigens by engrafted donor's lymphocytes is a known phenomenon in the setting of allogeneic hematopoietic stem cell transplantation (HSCT). This situation is usually clinically insignificant. We report a case of early clinically ...

journal_title：Transfusion

authors： Bailén R,Kwon M,Pérez-Corral AM,Pascual C,Buño I,Balsalobre P,Serrano D,Gayoso J,Díez-Martín JL,Anguita J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Absolute counts of CD4+ T-lymphocytes are used in the management of patients with human immunodeficiency virus infection. Low absolute counts of CD3+CD4+ cells have also been observed in healthy people--a phenomenon called idiopathic CD4 lymphocytopenia. It is common practice for normal ranges for lymphocyte...

journal_title：Transfusion

authors： Bryant JA,Wylie BR,Yuan FF,Ribeiro A,Thomson AR,Cooley MA,Fletcher A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The use of a platelet additive solution (PAS-II, Baxter) may have benefits over plasma for storage of platelets. It was the aim of this study to develop a method to produce WBC-reduced platelet concentrates (PCs) in PAS-II with >240 x 10(9) platelets and <1 x 10(6) WBCs per unit, which can be stored for 5 da...

journal_title：Transfusion

authors： van der Meer PF,Pietersz RN,Tiekstra MJ,Huijgens PC,Dekker WJ,Reesink HW

更新日期：2001-07-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is characterized by red blood cell (RBC) destruction in response to oxidative stress. Although blood donors are not routinely screened for G6PD deficiency, the transfusion of stored G6PD-deficient RBCs may have serious adverse outcomes. By measuring G6PD en...

journal_title：Transfusion

authors： Francis RO,Jhang J,Hendrickson JE,Zimring JC,Hod EA,Spitalnik SL

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Severe transfusion-related acute lung injury is often caused by antibodies directed against the human neutrophil alloantigen (HNA)-3a. HNA-3a results from an amino acid exchange (Arg154Gln) in the first extracellular loop of the choline transporter-like protein 2 (CTL2). The characteristics of the binding do...

journal_title：Transfusion

authors： Berthold T,Wesche J,Kuhnert K,Fürll B,Hippe H,Hoppen J,Reil A,Muschter S,Bux J,Greinacher A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

journal_title：Transfusion

authors： Rios J,Westra J,Dy B,Young PP

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:In cases of massive hemorrhage in the US military, improved outcomes have been reported with the use of warm, fresh whole blood transfusions. Cold-stored low-titer type O whole blood (LTOWB) has become the preferred product for resuscitation of severe bleeding in deployed surgical units. Reports of LTOWB use...

journal_title：Transfusion

authors： Bahr TM,DuPont TL,Morris DS,Pierson SE,Esplin MS,Brown SM,O'Brien EA,Ilstrup SJ,Christensen RD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:An HIV-1 and HCV NAT blood screening assay (Procleix HIV-1/HCV, Gen-Probe, Inc.) simultaneously detecting HIV-1 and HCV RNA) has been implemented. Donor plasma samples reactive in the Procleix HIV-1/HCV assay are tested with the HIV-1 and HCV discriminatory assays to resolve whether HIV-1 RNA, HCV RNA, or bo...

journal_title：Transfusion

authors： Vargo J,Smith K,Knott C,Wang S,Fang C,McDonough S,Giachetti C,Caglioti S,Gammon R,Gilbert D,Jackson JB,Richards W,Stramer S,Mimms L

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Antibodies specific for the neutrophil antigen HNA-3a cause severe, sometimes fatal transfusion-related acute lung disease (TRALI) when transfused, but it has not been possible to screen blood donors for anti-HNA-3a because using neutrophils as targets was impractical and molecular properties of the antigen ...

journal_title：Transfusion

authors： Curtis BR,Sullivan MJ,Holyst MT,Szabo A,Bougie DW,Aster RH

更新日期：2011-10-01 00:00:00

abstract：:In an attempt to gain insight into the motivations of blood donors and nondonors, two paper and pencil questionnaires were developed and mailed to approximately 7,000 individuals. In response, 1,429 nondonors and 200 donors completed and returned usable questionnaires. Among donors, awareness of the need for blood, al...

journal_title：Transfusion

authors： Leibrecht BC,Hogan JM,Luz GA,Tobias KI

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Most alloantigens on transfused red blood cells (RBCs) are weakly immunogenic, with only a 2 to 6 percent overall immunization rate even in patients receiving multiple transfusions. Although recipient genetics may contribute to responder and/or nonresponder status, in most cases HLA type does not predict hum...

journal_title：Transfusion

authors： Hendrickson JE,Desmarets M,Deshpande SS,Chadwick TE,Hillyer CD,Roback JD,Zimring JC

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Variant RHCE alleles with diminished expression of C, c, E, and e antigens have been described and indicate the genetic diversity of this gene locus in several populations. In this study the molecular background of variant RhCE antigens identified by standard serologic routine testing in German blood donors ...

journal_title：Transfusion

authors： Bugert P,Scharberg EA,Geisen C,von Zabern I,Flegel WA

更新日期：2009-09-01 00:00:00

abstract：:A 67-year-old white woman received transfusions of a total of 87 units of whole blood and red blood cells during and within 48 hours following a pneumonectomy. Although she had previously received blood transfusions, unexpected antibodies were not detectable by routine screening. On the second postoperative day, she d...

journal_title：Transfusion

authors： Chandeysson PL,Flye MW,Simpkins SM,Holland PV

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...

journal_title：Transfusion

authors： Assal A,Barlet V,Deschaseaux M,Dupont I,Gallian P,Guitton C,Morel P,David B,De Micco P

更新日期：2009-02-01 00:00:00