In vitro safety profile of G-CSF-mobilized whole blood after storage for 7 days in an infusable-grade L15 medium.

abstract：BACKGROUND:Studies analyzing motivation factors that lead to blood donation have found altruism to be the primary motivation factor; however, social capital has not been analyzed in this context. Our study examines the association between motivation factors (altruism, self-interest, and response to direct appeal) and s...

journal_title：Transfusion

authors： Gonçalez TT,Di Lorenzo Oliveira C,Carneiro-Proietti AB,Moreno EC,Miranda C,Larsen N,Wright D,Leão S,Loureiro P,de Almeida-Neto C,Lopes MI,Proietti FA,Custer B,Sabino E,NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), I

更新日期：2013-06-01 00:00:00

abstract：:A patient with T-polyagglutinable red cells and a severe coagulopathy provided an opportunity to observe the results of plasma transfusion in the face of T-activation. The patient was a 52-year-old Navajo Indian with a perforated gall bladder and related sepsis due to Clostridium perfringens. The gall bladder was remo...

journal_title：Transfusion

authors： Eversole M,Nonemaker B,Zurek K,South S,Simon T

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:The Joint Commission on the Accreditation of Healthcare Organizations requires that hospitals have a planned approach to systematically collect data on processes related to the use, ordering, and administering of blood components. This study describes how a comprehensive blood-administering assessment progra...

journal_title：Transfusion

authors： Saxena S,Ramer L,Shulman IA

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Variant Creutzfeldt-Jakob disease (vCJD) has been transmitted by blood transfusion (TTvCJD). The US Food and Drug Administration (FDA) recommends deferring blood donors who resided in or traveled to 30 European countries where they may have been exposed to bovine spongiform encephalopathy (BSE) through beef ...

journal_title：Transfusion

authors： Yang H,Huang Y,Gregori L,Asher DM,Bui T,Forshee RA,Anderson SA

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Reports of Monosomy 7 in patients receiving granulocyte-colony-stimulating factor (G-CSF) have raised concerns that this cytokine may promote genomic instability. However, there are no studies addressing whether repeated administration of G-CSF produces Monosomy 7 aneuploidy in healthy donors. STUDY DESIGN ...

journal_title：Transfusion

authors： Olnes MJ,Poon A,Miranda SJ,Pfannes L,Tucker Z,Loeliger K,Padilla-Nash H,Yau YY,Ried T,Leitman SF,Young NS,Sloand EM

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecules on RBCs may regulate ...

journal_title：Transfusion

authors： Khandelwal S,van Rooijen N,Saxena RK

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Changes within the ABO system are regularly observed phenomena in allogeneic bone marrow transplantation (BMT) and peripheral blood progenitor cell transplantation (PBPCT). Major ABO mismatch can lead to different clinical problems including acute hemolysis after infusion of the allograft, delay of red blood...

journal_title：Transfusion

authors： Scholl S,Klink A,Mügge LO,Schilling K,Höffken K,Sayer HG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Disquieting reports of increased complication and death rates after transfusions of red blood cells (RBCs) stored for more than 14 days prompted us to perform an observational retrospective cohort study of mortality in relation to storage time. STUDY DESIGN AND METHODS:We conducted a cohort study utilizing ...

journal_title：Transfusion

authors： Edgren G,Kamper-Jørgensen M,Eloranta S,Rostgaard K,Custer B,Ullum H,Murphy EL,Busch MP,Reilly M,Melbye M,Hjalgrim H,Nyrén O

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) with amotosalen HCl with ultraviolet A illumination inactivates pathogens and white blood cells in platelet (PLT) concentrates. STUDY DESIGN AND METHODS:In a Phase II crossover study, 32 patients with thrombocytopenia received one transfusion of PCT and/or one transfusion of un...

journal_title：Transfusion

authors： Slichter SJ,Raife TJ,Davis K,Rheinschmidt M,Buchholz DH,Corash L,Conlan MG

更新日期：2006-05-01 00:00:00

abstract：:Since the first issue of TRANSFUSION in 1961, there has been a tremendous expansion in not only the number of blood group antigens identified but also in our knowledge of their biochemical basis, function, and more recently, associated DNA changes. As certain techniques became available, our ability to discover and el...

journal_title：Transfusion

authors： Daniels G,Reid ME

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Preoperative autologous blood donation (PABD) has been used to reduce the need for allogeneic RBC transfusion, decreasing risk and conserving supply. A frozen PABD program for heart transplant patients was instituted at the Mayo Clinic in 1988, but participation has steadily declined. The aims of this study ...

journal_title：Transfusion

authors： Fontaine MJ,Winters JL,Moore SB,McGregor CG,Santrach PJ

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Cefotetan can cause severe immune hemolytic anemia that may persist long after the drug is discontinued. To study the binding of cefotetan to RBCs, patients who received cefotetan were followed and tested for the presence of antibody to cefotetan. STUDY DESIGN AND METHODS:Patients receiving cefotetan were i...

journal_title：Transfusion

authors： Davenport RD,Judd WJ,Dake LR

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：:In spite of growing awareness of the potential risks associated with transfusion, the number of platelet units transfused in the United States continues to increase each year. There is a growing interest in ensuring that all transfusions are administered for appropriate reasons. Prospective review of requests for tran...

journal_title：Transfusion

authors： Sielaff BH,Scott EP,Connelly DP

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Exposure to blood products during pregnancy carries a potential risk of transfusion transmission of infectious agents. Blood agencies have historically sought optimal deferral and testing strategies to protect blood supplies in part to ensure the protection of pregnant women and their unborn infants. The Zik...

journal_title：Transfusion

authors： Murphy MS,Shehata N,Colas JA,Chassé M,Fergusson DA,O'Brien SF,Goldman M,Tinmouth A,Forster AJ,Wilson K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

journal_title：Transfusion

authors： Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The capability of holding whole blood (WB) units at ambient temperature, overnight, should help in platelet (PLT) concentrate preparation logistics. We summarize the results of a study conducted in the early 1990s that compared, in particular, PLT and red blood cell (RBC) in vivo viability properties followi...

journal_title：Transfusion

authors： Moroff G,AuBuchon JP,Pickard C,Whitley PH,Heaton WA,Holme S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to explore the molecular basis of the p phenotype by analysis of the recently cloned 4-alpha-galactosyltransferase gene responsible for synthesis of Pk (Gb3) antigen. STUDY DESIGN AND METHODS:Forty samples from individuals of eight different nationalities were investigated by s...

journal_title：Transfusion

authors： Hellberg A,Steffensen R,Yahalom V,Sojka BN,Heier HE,Levene C,Poole J,Olsson ML

更新日期：2003-07-01 00:00:00

abstract：:This study evaluated the effect of pneumatic tube transport on blood bank specimens and products. No important differences were found between aliquots transported in the tube system and those stored in the laboratory as controls. ABO, Rh, antibody detection or identification, direct antiglobulin testing, and elution w...

journal_title：Transfusion

authors： Tanley PC,Wallas CH,Abram MC,Richardson LD

更新日期：1987-03-01 00:00:00

abstract：:A procedure is described for the large-scale production of pure suspensions of human lymphocytes and granulocytes. Platelet-poor buffy-coats, obtained by centrifugation of six units of ABO-compatible ACD blood, were pooled and centrifuged again, resulting in a crude leukocyte concentrate containing approximately 60 pe...

journal_title：Transfusion

authors： de la Rivière AB,Verhoef-Karssen PR,de Wit JJ,Loos JA,Prins HK

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The history of the development and implementation of the Brazilian nucleic acid testing (NAT) platform to detect and discriminate among human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) infections in blood donors is described here. The results for the sensitivity, repro...

journal_title：Transfusion

authors： Rocha D,Andrade E,Godoy DT,Fontana-Maurell M,Costa E,Ribeiro M,Ferreira AGP,Brindeiro R,Tanuri A,Alvarez P

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Blood centers and hospital transfusion services are challenged with maintaining an adequate platelet (PLT) inventory to minimize the number of outdated units without risking a major shortage. A novel approach to inventory management was established at our institution through a collaboration between the Stanf...

journal_title：Transfusion

authors： Fontaine MJ,Chung YT,Rogers WM,Sussmann HD,Quach P,Galel SA,Goodnough LT,Erhun F

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:A new citrate-acetate-NaCl platelet additive solution, identified as PAS 2, was developed to prepare platelet concentrates (PCs) from pooled 0.5 CPD buffy coats (BCs). STUDY DESIGN AND METHODS:A study was undertaken to evaluate PAS 2 in vitro (n = 8) and in vivo (n = 9) against a commercially available solu...

journal_title：Transfusion

authors： van Rhenen DJ,Vermeij H,Kappers-Klunne M,Payrat JM

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Among labile blood products, platelet concentrates (PCs) are the leading cause of hypersensitivity transfusion reactions (HTRs). These reactions often lead to interruption of PC transfusion and can result in a prolonged transfusion process leading to significant morbidity and use of premedication and close m...

journal_title：Transfusion

authors： Mertes PM,Tacquard C,Andreu G,Kientz D,Gross S,Malard L,Drouet C,Carlier M,Gachet C,Sandid I,Boudjedir K

更新日期：2020-03-01 00:00:00

abstract：:Evidence supporting the existence of two agents of human non-A, non-B hepatitis was obtained by the inoculation of chimpanzees sequentially with serum from a chronically infected human (Inoculum I) and with fibrinogen prepared from pooled plasma (Inoculum IV), each of which had transmitted non-A, non-B hepatitis to hu...

journal_title：Transfusion

authors： Tabor E,Snoy P,Jackson DR,Schaff Z,Blatt PM,Gerety RJ

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...

journal_title：Transfusion

authors： D'Alessandro A,Thomas KA,Stefanoni D,Gamboni F,Shea SM,Reisz JA,Spinella PC

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...

journal_title：Transfusion

authors： Wang B,Schreiber GB,Glynn SA,Nass CC,Smith JW,Higgins MJ,Hutching ST,Wright DJ,McEntire RL,Murphy EL,Retrovirus Epidemiology Donor Study.

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The FDA requirement for sensitivity of viral NAT methods used in blood screening is a 95-percent detection limit of 100 copies per mL, whereas the NAT screening system should have a sensitivity of at least 5000 copies per mL per individual donation. According to the Common Technical Specifications of the Eur...

journal_title：Transfusion

authors： Lelie PN,van Drimmelen HA,Cuypers HT,Best SJ,Stramer SL,Hyland C,Allain JP,Moncharmont P,Defer C,Nübling M,Glauser A,da Silva Cardoso M,Viret JF,Lankinen MH,Grillner L,Wirthmüller U,Coste J,Schottstedt V,Masecar B,D

更新日期：2002-05-01 00:00:00

abstract：:A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

journal_title：Transfusion

authors： Ellisor SS,Shoemaker MM,Reid ME

更新日期：1982-05-01 00:00:00