Iron supplementation in female blood donors deferred by copper sulfate screening.

Abstract:

:Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their suitability to donate blood, were determined initially (Visit 1) and at four follow-up visits (Visits 2-5). By the second visit, the serum ferritin and iron values of donors receiving iron supplementation differed significantly from those of donors receiving placebo. By the fifth visit, a less marked but significant increase in hemoglobin had occurred in the iron group, but not in the placebo group. At no time was there a significant difference between the groups' suitability to donate blood, with each group donating at almost half of their visits. The authors conclude that iron supplementation at this dose level in deferred female blood donors improves their iron status and hemoglobin levels, but does not significantly increase their suitability to donate blood as compared with the suitability of placebo-treated donors.

journal_name

Transfusion

journal_title

Transfusion

authors

Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

doi

10.1046/j.1537-2995.1988.28588337328.x

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

422-6

issue

5

eissn

0041-1132

issn

1537-2995

journal_volume

28

pub_type

临床试验,杂志文章,随机对照试验
  • Liquid storage at 4 degrees C of previously frozen red cells.

    abstract::Fresh human blood was collected in citrate-phosphate-dextrose, frozen by a high-glycerol technique, and stored at -80 degrees C. The red cells were thawed, deglycerolized, and resuspended in a final wash solution, ADSOL (Fenwal Laboratories), or an additive solution (AS) containing glucose, adenine, mannitol, and phos...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27688071704.x

    authors: Moore GL,Ledford ME,Mathewson PJ,Hankins DJ

    更新日期:1987-11-01 00:00:00

  • Functional antibodies to Haemophilus influenzae type B, Neisseria meningitidis, and Streptococcus pneumoniae contained in intravenous immunoglobulin products.

    abstract:BACKGROUND:Intravenous immunoglobulin G (IVIG) replacement therapy is used to prevent invasive infections in patients with primary antibody deficiency (PAD). However, few studies have functionally evaluated specific antibodies against encapsulated bacteria that cause invasive infection in patients with PAD. In this stu...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13869

    authors: Lee S,Kim HW,Kim KH

    更新日期:2017-01-01 00:00:00

  • Analysis of exome sequencing data sets reveals structural variation in the coding region of ABO in individuals of African ancestry.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13797

    authors: Fox K,Johnsen JM,Coe BP,Frazar CD,Reiner AP,NHLBI Exome Sequencing Project, Minority Health-GRID Network.,Eichler EE,Nickerson DA

    更新日期:2016-11-01 00:00:00

  • Characteristics of thawed autologous umbilical cord blood.

    abstract:BACKGROUND:Autologous umbilical cord blood (AutoUCB) has historically been cryopreserved for potential use in hematopoietic transplantation. Increasingly, private AutoUCB banking is performed for therapies unavailable today. A Phase I trial using AutoUCB treatment for early pediatric Type 1 diabetes afforded us an oppo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03556.x

    authors: Rosenau EH,Sugrue MW,Haller M,Fisk D,Kelly SS,Chang M,Hou W,Eldjerou L,Slayton W,Cogle CR,Wingard JR

    更新日期:2012-10-01 00:00:00

  • A comparative study of reducing the extracellular potassium concentration in red blood cells by washing and by reduction of additive solution.

    abstract:BACKGROUND:Extracellular potassium concentration (K(+)) increases in the supernatant of whole and packed red blood cell units (pRBCs) with duration of refrigerated storage in citrate-phosphate-dextrose-adenine (CPDA-1) and additive solution (AS). Studies have shown that to avoid hyperkalemia, washed pRBCs are preferred...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01095.x

    authors: Bansal I,Calhoun BW,Joseph C,Pothiawala M,Baron BW

    更新日期:2007-02-01 00:00:00

  • Red cell alloantibodies in thalassemia major. Results of an Italian cooperative study.

    abstract::Clinical and serological data on 1435 Italian thalassemia major patients were collected during a cooperative study involving 19 centers in 10 regions. The main findings were as follows: 18 percent of the patients were under 6 years of age, 63 percent between 6 and 15, and 19 percent over 15. Forty-one percent had unde...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1985.25285169198.x

    authors: Sirchia G,Zanella A,Parravicini A,Morelati F,Rebulla P,Masera G

    更新日期:1985-03-01 00:00:00

  • Comparison of a manual hexadimethrine bromide-antiglobulin test with saline- and albumin-antiglobulin tests for pretransfusion testing.

    abstract::A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27287150183.x

    authors: Mintz PD,Anderson G

    更新日期:1987-03-01 00:00:00

  • Evaluation of the National Healthcare Safety Network Hemovigilance Module for transfusion-related adverse reactions in the United States.

    abstract:INTRODUCTION:The National Healthcare Safety Network (NHSN) Hemovigilance Module (HM) collects data on the frequency, severity, and imputability of transfusion-associated adverse events. These events contribute to significant morbidity and mortality among transfusion patients. We report results from the first systematic...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15008

    authors: Edens C,Haass KA,Cumming M,Osinski A,O'Hearn L,Passanisi K,Eaton L,Visintainer P,Savinkina A,Kuehnert MJ,Basavaraju SV,Andrzejewski C

    更新日期:2019-02-01 00:00:00

  • Can the interval between antibody identifications be increased for alloimmunized patients?

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13380

    authors: Goss C,Avecilla ST,Garbaini J,Degtyaryova D,Lo D,Chang DY,Cushing M

    更新日期:2016-02-01 00:00:00

  • Is placental blood a reliable source for the evaluation of neonatal hemostasis at birth?

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15785

    authors: Raffaeli G,Tripodi A,Manzoni F,Scalambrino E,Pesenti N,Amodeo I,Cavallaro G,Villamor E,Peyvandi F,Mosca F,Ghirardello S

    更新日期:2020-05-01 00:00:00

  • Bacterial screening of apheresis platelets with a rapid test: a 113-month single center experience.

    abstract:BACKGROUND:The 2016 Food and Drug Administration draft guidance describes the use of a rapid test (RT) to enhance platelet transfusion safety and availability. This study reports a 113-month experience of screening of apheresis platelets (APs) by RT. STUDY DESIGN AND METHODS:From July 2008 to October 2015, all APs und...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14629

    authors: Ruby KN,Thomasson RR,Szczepiorkowski ZM,Dunbar NM

    更新日期:2018-07-01 00:00:00

  • A comparison of human immunodeficiency virus, hepatitis C virus, hepatitis B virus, and human T-lymphotropic virus marker rates for directed versus volunteer blood donations to the American Red Cross during 2005 to 2010.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03904.x

    authors: Dorsey KA,Moritz ED,Steele WR,Eder AF,Stramer SL

    更新日期:2013-06-01 00:00:00

  • Dimethyl sulfoxide: effects on function of fresh platelets and on the viability of platelets in storage.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1983.23283172844.x

    authors: Fratantoni JC,Poindexter BJ

    更新日期:1983-03-01 00:00:00

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03000.x

    authors: Ghio M,Contini P,Negrini S,Mazzei C,Zocchi MR,Poggi A

    更新日期:2011-07-01 00:00:00

  • Does therapeutic plasma exchange have a role in the treatment of prosthetic hip-associated cobalt toxicity? A case report and literature review.

    abstract:BACKGROUND:Prosthetic hip-associated cobalt toxicity (PHACT) is an uncommon, but potentially devastating, complication for patients with metal-on-metal hip implants (MoMs). Clinical management of PHACT is poorly defined, with primary intervention being MoM explant followed by chelation therapy. Therapeutic plasma excha...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.13720

    authors: Grant ML,Karp JK,Palladino M,Le N,Hall N,Herman JH

    更新日期:2016-09-01 00:00:00

  • Inactivation of viruses in platelet concentrates by photochemical treatment with amotosalen and long-wavelength ultraviolet light.

    abstract:BACKGROUND:Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical treatment (PCT) process with amotosalen-HCl and long-wavelength ultraviolet light (UVA), which cross-links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentra...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.0041-1132.2005.04316.x

    authors: Lin L,Hanson CV,Alter HJ,Jauvin V,Bernard KA,Murthy KK,Metzel P,Corash L

    更新日期:2005-04-01 00:00:00

  • Incidence of breakage of human RBCs frozen with 40-percent wt/vol glycerol using two different methods for storage at -80 degrees C.

    abstract:BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00317.x

    authors: Valeri CR,Lane JP,Srey R,Ragno G

    更新日期:2003-03-01 00:00:00

  • Monitoring for underutilization of RBC components and platelets.

    abstract:BACKGROUND:Monitoring blood transfusion for overutilization is standard practice at most institutions. STUDY DESIGN AND METHODS:This study monitored for underutilization of blood transfusion over a 14-month period, by evaluating patients who had Hb levels that were reported to be <5 g per dL or platelet counts <10 x 1...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41050587.x

    authors: Saxena S,Wehrli G,Makarewicz K,Sartorelli J,Shulman IA

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  • A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells.

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    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01793.x

    authors: Semple JW,Speck ER,Fabron A Jr,Kim RA,Freedman J

    更新日期:2008-09-01 00:00:00

  • A Bombay individual lacking H and Le antigens but expressing normal levels of alpha-2- and alpha-4-fucosyltransferases.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1995.35996029164.x

    authors: Shechter Y,Etzioni A,Levene C,Greenwell P

    更新日期:1995-09-01 00:00:00

  • Field-expedient thawing of fresh-frozen plasma.

    abstract:INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15652

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    更新日期:2020-06-01 00:00:00

  • Platelet glycolytic flux increases stimulated by ultraviolet-induced stress is not the direct cause of platelet morphology and activation changes: possible implications for the role of glucose in platelet storage.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00582.x

    authors: Li J,Goodrich L,Hansen E,Edrich R,Gampp D,Goodrich RP

    更新日期:2005-11-01 00:00:00

  • Delayed hemolytic transfusion reaction caused by anti-P1 antibody.

    abstract::A 67-year-old white woman received transfusions of a total of 87 units of whole blood and red blood cells during and within 48 hours following a pneumonectomy. Although she had previously received blood transfusions, unexpected antibodies were not detectable by routine screening. On the second postoperative day, she d...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1981.21181127489.x

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    更新日期:1981-01-01 00:00:00

  • Identification and quantitation of the protein content of blood group antibody eluates prepared by the rapid acid-stromal method. Use in committed erythroid progenitor cell assays.

    abstract::Anti-D sensitized red cells were converted to stroma, either by digitonin or hypotonic lysis, and eluates prepared by the modified rapid acid-stromal method. SDS-PAGE and both rocket- and crossed-immunoelectrophoresis showed that, of the total protein content of the eluates, 11 to 25 percent was IgG, 18 to 45 percent ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1983.23383224906.x

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    更新日期:1983-05-01 00:00:00

  • How do we perform and bill for blood bank physician consultative services?

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14264

    authors: Jhang JS,Francis RO,Winkler A,Tormey C

    更新日期:2017-10-01 00:00:00

  • Estimating the risk of blood donation fainting for self versus others: the moderating effect of fear.

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    pub_type: 杂志文章

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    更新日期:2019-06-01 00:00:00

  • Benefits to blood banks of a sales and operations planning process.

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    pub_type: 杂志文章

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    更新日期:2010-12-01 00:00:00

  • The in vitro evaluation of modifications in CPD-adenine anticoagulated-preserved blood at various hematocrits.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1980.20480260273.x

    authors: Moore GL,Ledford ME,Peck CC

    更新日期:1980-07-01 00:00:00

  • Sterility and quality of blood dispensed in syringes for infants.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26286152907.x

    authors: Strauss RG,Crawford GF,Elbert C,Floss AM,Liesch M

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  • Continuous- and semicontinuous-flow blood centrifugation systems: therapeutic applications, with plasma-, platelet, lympha-, and eosinapheresis.

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    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17578014576.x

    authors: Pineda AA,Brzica SM Jr,Taswell HF

    更新日期:1977-09-01 00:00:00