Iron supplementation in female blood donors deferred by copper sulfate screening.

abstract：:After 30 years of hematopoietic stem cell use for various indications, umbilical cord blood is considered as an established source of cells with marrow and postmobilization peripheral blood. The limited number of cells still remains a problematic element restricting their use, especially in adults who require to be gr...

journal_title：Transfusion

authors： Faivre L,Couzin C,Boucher H,Domet T,Desproges A,Sibony O,Bechard M,Vanneaux V,Larghero J,Cras A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The FcgammaRIIA gene is expressed in two polymorphic forms, R131 and H131, which differ by the replacement of histidine by arginine at position 131. The FCGR3B (FcgammaRIIIB) gene exists in two allelic isoforms, known as FCGR3B1 (FcgammaRIIIB-NA1) and FCGR3B2 (FcgammaRIIIB-NA2), which differ in nucleotides 1...

journal_title：Transfusion

authors： Kuwano ST,Bordin JO,Chiba AK,Mello AB,Figueiredo MS,Vieira-Filho JP,Fabron A Jr,Kerbauy J

更新日期：2000-11-01 00:00:00

abstract：:In spite of growing awareness of the potential risks associated with transfusion, the number of platelet units transfused in the United States continues to increase each year. There is a growing interest in ensuring that all transfusions are administered for appropriate reasons. Prospective review of requests for tran...

journal_title：Transfusion

authors： Sielaff BH,Scott EP,Connelly DP

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

journal_title：Transfusion

authors： Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Liberal transfusion strategy increases the risk of acute lung injury (ALI), but specific transfusion-related factors have not been characterized. We tested the hypotheses that storage age and specific type of blood products are associated with increased risk of ALI in mechanically ventilated patients. STUDY...

journal_title：Transfusion

authors： Gajic O,Rana R,Mendez JL,Rickman OB,Lymp JF,Hubmayr RD,Moore SB

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The Spectra Optia (SPO; CaridianBCT) is a new apheresis device based on the COBE Spectra (CSP; CaridianBCT) platform. This study was designed to evaluate the safety and efficiency of the SPO in comparison to the predicate CSP device. STUDY DESIGN AND METHODS:Twenty patients were recruited for a randomized, ...

journal_title：Transfusion

authors： Tormey CA,Peddinghaus ME,Erickson M,King KE,Cushing MM,Bill J,Goodrich T,Snyder EL

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Monitoring of patients' vital sign values (VSVs) during hemotherapy may have an important role in the recognition and mitigation of transfusion-associated circulatory overload (TACO). Knowledge regarding VSVs and other patient characteristics in bedside-reported TACO or fluid challenge-suspected transfusion ...

journal_title：Transfusion

authors： Andrzejewski C Jr,Popovsky MA,Stec TC,Provencher J,O'Hearn L,Visintainer P,Steingrub J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Senescent RBCs bear IgG and C3 opsonins that are three to four times less than required for similar phagocytosis of experimentally opsonized RBCs. STUDY DESIGN AND METHODS:Studies were performed to determine the phagocyte receptors involved in phagocytosis in vitro. The effect of clustering of opsonins and ...

journal_title：Transfusion

authors： Tartakover-Matalon S,Shoham-Kessary H,Foltyn V,Gershon H

更新日期：2000-12-01 00:00:00

abstract：:Clinical and serological data on 1435 Italian thalassemia major patients were collected during a cooperative study involving 19 centers in 10 regions. The main findings were as follows: 18 percent of the patients were under 6 years of age, 63 percent between 6 and 15, and 19 percent over 15. Forty-one percent had unde...

journal_title：Transfusion

authors： Sirchia G,Zanella A,Parravicini A,Morelati F,Rebulla P,Masera G

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) antigen and antibody combination assays have been launched as a cost-effective alternative to nucleic acid testing (NAT) for reducing the antibody-negative window period (WP). Later, a HCV antigen chemiluminescence immunoassay (CLIA) became available. STUDY DESIGN AND METHODS:A panel...

journal_title：Transfusion

authors： Laperche S,Nübling CM,Stramer SL,Brojer E,Grabarczyk P,Yoshizawa H,Kalibatas V,El Elkyabi M,Moftah F,Girault A,van Drimmelen H,Busch MP,Lelie N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This study investigated the effects of a 6-month deferral due to low hemoglobin (Hb) on the subsequent donation patterns of Australian whole blood donors. STUDY DESIGN AND METHODS:The study was a retrospective cohort study of the donation patterns of all whole blood donors deferred for low Hb during a 2-mon...

journal_title：Transfusion

authors： Hillgrove T,Moore V,Doherty K,Ryan P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is common in transfused patients. Most studies report on the rate of alloimmunization in chronically transfused patients, which can be as high as 60 percent. Less is known on the incidence of clinically relevant antibodies in accidentally transfused patients. Because the...

journal_title：Transfusion

authors： Schonewille H,van de Watering LM,Brand A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Much effort and resources have been devoted to programs that provide transfusion support for patients with sickle cell disease (SCD). The focus of many donor programs is to prevent alloimmunization by recruiting racially matched African American donors to limit the red blood cell (RBC) antigenic differences ...

journal_title：Transfusion

authors： Karafin MS,Field JJ,Gottschall JL,Denomme GA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Passive immunotherapy in human immunodeficiency virus (HIV) infection is based on transfusions of plasma that is rich in HIV antibodies. STUDY DESIGN AND METHODS:To verify whether the clearance of transfused antibodies will maintain an elevated titer of specific antibodies between biweekly transfusions of p...

journal_title：Transfusion

authors： Lefrère JJ,Roudot-Thoraval F,Vittecoq D,Heshmati F,Audat F,Lerable J,Reed D,Petit JC,Burghoffer B,Morand-Joubert L

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:The Verax PGD rapid test for bacteria in platelets (PLTs) has been updated to simplify workflow and improve specificity and sensitivity by employing a novel sequential format. The performance of this updated version, called PGDprime, was evaluated to determine its suitability for use as an FDA-cleared "safet...

journal_title：Transfusion

authors： Vallejo RP,Shinefeld L,LaVerda D,Best N,Lawrence G,Lousararian A,Hornbaker N,Rasmusson P,Mintz PD

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

journal_title：Transfusion

authors： Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The potential hemostatic effect of infusible platelet membranes (IPM; Cyplex, Cypress Bioscience) prepared from outdated human platelets is investigated. STUDY DESIGN AND METHODS:Increasing concentrations of IPM were added to blood samples anticoagulated with low-molecular-weight heparin, in which platelets...

journal_title：Transfusion

authors： Galán AM,Bozzo J,Hernández MR,Pino M,Reverter JC,Mazzara R,Escolar G,Ordinas A

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Aprotinin has been reapproved for use in Europe and in Canada. We sought to determine if its reintroduction was still pertinent given the widespread administration of tranexamic acid, another antifibrinolytic shown to reduce bleeding and transfusions. STUDY DESIGN AND METHODS:After institutional review boar...

journal_title：Transfusion

authors： Stevens LM,Noiseux N,Prieto I,Hardy JF

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:WBC reduction of cellular blood components has been introduced in many countries. Owing to concerns of residual WBCs in plasma, a new method to collect WBC-reduced plasma by apheresis was studied. STUDY DESIGN AND METHODS:An apheresis machine (PCS2, Haemonetics) was used, in combination with the "high-separ...

journal_title：Transfusion

authors： Vrielink H,van der Meer PF

更新日期：2004-06-01 00:00:00

abstract：:During a 22-month period, 78,000 blood donors were screened for human T-lymphotropic virus types I and II (HTLV-I/II) at Belle Bonfils Memorial Blood Center (Denver, Colorado). Positive donors and the living recipients of their previously donated blood components were evaluated for risk factors and symptoms related to...

journal_title：Transfusion

authors： Herr V,Ambruso D,Fairfax M,Neumann A,Swanson P,Lee H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Clinical performance of human platelet (PLT) products processed or stored under novel conditions is difficult to predict based on in vitro studies alone. Recovery and survival of radiolabeled PLTs in human subjects are used as surrogate markers for PLT efficacy in development of new products. Such experiment...

journal_title：Transfusion

authors： Piper JT,Gelderman MP,Vostal JG

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:G-CSF-mobilized whole blood (WB) is a cost-reducing and simple alternative for peripheral blood progenitor cell transplantation. Recently, it was demonstrated that mobilized WB supplemented with Leibovitz's L15 medium permitted prolonged preservation of clonogenic cells at ambient temperature. In this study,...

journal_title：Transfusion

authors： de Kreuk AM,Jonkhoff AR,Zevenbergen A,Wilhelm AJ,van Oostveen JW,Schuurhuis GJ,Huijgens PC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:If anti-hepatitis B core antibody testing is not mandated blood donors with occult hepatitis B infection (OBI) may transmit hepatitis B virus (HBV) to a recipient in spite of the use of nucleic acid amplification technology (NAT) or pathogen inactivation (PI). STUDY DESIGN AND METHODS:We developed a model t...

journal_title：Transfusion

authors： Weusten J,van Drimmelen H,Vermeulen M,Lelie N

更新日期：2017-03-01 00:00:00

abstract：:In an attempt to gain insight into the motivations of blood donors and nondonors, two paper and pencil questionnaires were developed and mailed to approximately 7,000 individuals. In response, 1,429 nondonors and 200 donors completed and returned usable questionnaires. Among donors, awareness of the need for blood, al...

journal_title：Transfusion

authors： Leibrecht BC,Hogan JM,Luz GA,Tobias KI

更新日期：1976-03-01 00:00:00

abstract：:Fatal postoperative erythroderma (POE) developed in a 52-year-old woman with gallstones who underwent elective cholecystectomy. During surgery, she was transfused with 3 units of unirradiated packed red cells stored in the liquid state for at least 4 days after collection. The POE is believed to have been the result o...

journal_title：Transfusion

authors： Otsuka S,Kunieda K,Hirose M,Takeuchi H,Mizutani Y,Nagaya M,Sato G,Kasuya S,Matsutomo K,Noma A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The AMICUS (Fenwal, Inc.) was cleared in the United States for platelet (PLT) and plasma collection in 1996 with subsequent clearances for the collection of other blood products. Although not previously used for therapeutic plasma exchange (TPE), new disposables, software, and hardware were developed to enab...

journal_title：Transfusion

authors： Winters JL,Burgstaler EA,Gottschall JL,Balogun RA,Houghton JR,Lee WJ,Snyder EL

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The severe acute respiratory syndrome (SARS) was first described in February 2003. Close contact with symptomatic patients appears to be the main route of transmission, whereas blood transfusion transmission could not be ruled out. STUDY DESIGN AND METHODS:A SARS coronavirus (SARS-CoV) detection kit develop...

journal_title：Transfusion

authors： Schmidt M,Brixner V,Ruster B,Hourfar MK,Drosten C,Preiser W,Seifried E,Roth WK

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The anti-CD20 monoclonal antibody rituximab has immune-modulatory effects similar to intravenous immunoglobulin (IVIG). We performed a systematic review and meta-analysis to determine the efficacy and safety of rituximab in autoimmune diseases that are also treated with IVIG. STUDY DESIGN AND METHODS:The mo...

journal_title：Transfusion

authors： MacIsaac J,Siddiqui R,Jamula E,Li N,Baker S,Webert KE,Evanovitch D,Heddle NM,Arnold DM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：:Alanine aminotransferase (ALT) phenotype and serum activities were determined in 200 random volunteer blood donors. Serum enzyme activities were not significantly affected by the ALT phenotype (p greater than 0.1). Studies on 500 random volunteer blood donors showed significant differences in serum ALT levels between ...

journal_title：Transfusion

authors： Savage B,Sayers MH,Giblett ER

更新日期：1982-07-01 00:00:00