NBTS/BRIC 8. A monoclonal anti-C3d antibody.

abstract：BACKGROUND:Umbilical cord blood (UCB) can be used as hematopoietic stem cell source for transplantation. The success of a transplantation is highly correlated with the number of total nucleated cells (TNCs) and CD34+ cells in the UCB. Certain obstetric factors increase the yield of stem cells in the UCB. It is necessar...

journal_title：Transfusion

authors： Manegold G,Meyer-Monard S,Tichelli A,Pauli D,Holzgreve W,Troeger C

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Chronic transfusion in sickle cell disease (SCD) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. The aim of our study was to assess the safety and efficacy of automated red blood cell exchange (aRBX) in patients with SCD pre...

journal_title：Transfusion

authors： Dedeken L,Lê PQ,Rozen L,El Kenz H,Huybrechts S,Devalck C,Diallo S,Heijmans C,Ferster A

更新日期：2018-06-01 00:00:00

abstract：:The effects of dextran therapy on pretransfusion compatibility testing were evaluated in 24 patients with a variety of vascular disorders. Specimens were drawn before, during, and after the administration of low-molecular-weight dextran (average molecular weight, 40 kd). Forty-three specimens were studied extensively ...

journal_title：Transfusion

authors： Bartholomew JR,Bell WR,Kickler T,Williams GM

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:All published reports have described methods for virus photoinactivation which significantly alter red cell (RBC) properties during storage. In order to improve virucidal activity and reduce damage to RBCs, a series of phenothiazine derivatives were either synthesized or purified and screened for bacteriopha...

journal_title：Transfusion

authors： Wagner SJ,Skripchenko A,Robinette D,Mallory DA,Cincotta L

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Iron overload is a common complication of patients with β-thalassemia major (TM). Despite the availability of three iron chelators, deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), some patients fail to respond adequately to monotherapy with any of them. We report a case of TM who had refractory...

journal_title：Transfusion

authors： Voskaridou E,Komninaka V,Karavas A,Terpos E,Akianidis V,Christoulas D

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The Le(a) and Le(b) antigens are synthesized by cells making exocrine secretions, but it is not well-defined where plasma and red cell Le(a) and Le(b) antigens are made. STUDY DESIGN AND METHODS:This study uses chromatographic and immunochemical methods to extract Le(a) and Le(b) glycolipids from human tiss...

journal_title：Transfusion

authors： Hauser R

更新日期：1995-07-01 00:00:00

abstract：:A prospective study of newborn infants who required exchange transfusion was undertaken to evaluate the risk of transmission of cytomegalovirus (CMV). Buffy coat-, urine- and saliva-saturated throat swabs for viral cultures and serum specimens for CMV complement-fixing (CF) antibody were obtained from 45 infant-mother...

journal_title：Transfusion

authors： Kumar A,Nankervis GA,Cooper AR,Gold E,Kumar ML

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Because single-donor plateletpheresis concentrates now account for a large percentage of PLT concentrates, the PLT quality of individual donations is increasingly important. There has been little previous work on PLT function in blood donors. STUDY DESIGN AND METHODS:The aim of this study was to investigate...

journal_title：Transfusion

authors： Harrison P,Segal H,Furtado C,Verjee S,Sukhu K,Murphy MF

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Posttransfusion graft-versus-host disease (PT-GVHD) is underdiagnosed and underreported. Risk factors predisposing to PT-GVHD in newborn recipients, the clinical manifestations of the disease in newborns, and its mechanism are not well characterized. STUDY DESIGN AND METHODS:A literature review identified 2...

journal_title：Transfusion

authors： Ohto H,Anderson KC

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Human herpesvirus 8 (HHV-8) seroprevalence ranges between less than 5% in Europe and North America and 50% to 70% in sub-Saharan Africa. Evidence of HHV-8 transfusion transmission is only indirect. We conducted a serologic (anti-HHV-8) and molecular (HHV-8 DNA) study of samples from paired donor-immunocompet...

journal_title：Transfusion

authors： Gobbini F,Owusu-Ofori S,Marcelin AG,Candotti D,Allain JP

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

journal_title：Transfusion

authors： Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:A highly sensitive dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA) and flow cytometry techniques have previously been developed and employed to characterize soluble cellular prion protein (PrP(c)) expression in whole blood and separated components from healthy adult blood donors. No previous stud...

journal_title：Transfusion

authors： Fagge T,Barclay GR,Macgregor I,Head M,Ironside J,Turner M

更新日期：2005-04-01 00:00:00

abstract：:Many strides were made in the field of blood transfusion before and during World War I. However, it was not until after the war that one of the most exciting and controversial episodes in the field of blood transfusion occurred. Review of the literature revealed the 1920s to be a tumultuous era filled with conflicting...

journal_title：Transfusion

authors： Wain SL

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:In 1996, the Danish National Board of Health recommended hepatitis C virus (HCV) lookback to identify recipients of blood components from donors found to be positive since the implementation of anti-HCV screening in 1991. STUDY DESIGN AND METHODS:The aim was to accumulate results of the lookback at a nation...

journal_title：Transfusion

authors： Christensen PB,Groenbaek K,Krarup HB

更新日期：1999-02-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：:The development of a synthetic medium for platelet storage is an important goal in transfusion medicine. Its use would make large volumes of plasma available for fractionation and might improve the quality of platelets after storage. Several investigators have described successful storage in media containing acetate. ...

journal_title：Transfusion

authors： Shimizu T,Murphy S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Transfusion of bacterially contaminated platelet concentrates (PCs) can result in serious health consequences for the affected patient. Before being released from blood banking facilities, PCs are routinely screened for bacterial contamination by culture-based tests. However, culture-based PC screening metho...

journal_title：Transfusion

authors： Zweitzig DR,Riccardello NM,Pester JM,Jeanmonod R,Kopnitsky MJ,O'Hara SM

更新日期：2014-06-01 00:00:00

abstract：:Blood centrifugation, with a continuous-flow or semicontinuous-flow system, was used in the treatment of 17 patients with various hematologic disorders. Total plasma exchange (TPE) controlled symptoms of hyperviscosity and arrested bleeding in three patients. In two patients, TPE made is possible to perform urgent sur...

journal_title：Transfusion

authors： Pineda AA,Brzica SM Jr,Taswell HF

更新日期：1977-09-01 00:00:00

abstract：:Japanese encephalitis virus (JEV) is endemic to tropical areas in Asia and the Western Pacific. It can cause fatal encephalitis, although most infected individuals are asymptomatic. JEV is mainly transmitted to humans through the bite of an infected mosquito, but can also be transmitted through blood transfusion. To m...

journal_title：Transfusion

authors： Rustanti L,Hobson-Peters J,Colmant AMG,Hall RA,Young PR,Reichenberg S,Tolksdorf F,Sumian C,Gravemann U,Seltsam A,Marks DC,Faddy HM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick r...

journal_title：Transfusion

authors： Clavier B,Pouget T,Sailliol A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery ...

journal_title：Transfusion

authors： Balint B,Paunovic D,Vucetic D,Vojvodic D,Petakov M,Trkuljic M,Stojanovic N

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated that immunity against platelet (PLT) transfusions is dependent on recipient antigen-presenting cells (APCs) and their ability to produce nitric oxide (NO). To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO(-)) and its ability to affect PLT immunity. S...

journal_title：Transfusion

authors： Semple JW,Speck ER,Fabron A Jr,Kim RA,Freedman J

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Since their description in the 1970s, anti-Hr(B) (antibody against a high-prevalence Rh antigen) and anti-hr(B) (anti-e-like antibody) are still a subject of debate about representing two aspects of a global immune response or being two independent antibodies. STUDY DESIGN AND METHODS:The aim of this study ...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Tourret S,Beolet M,Many H,Juszczak G,Roussel M,Kappler-Gratias S,Rouger P,Le Pennec PY

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...

journal_title：Transfusion

authors： Wang B,Schreiber GB,Glynn SA,Nass CC,Smith JW,Higgins MJ,Hutching ST,Wright DJ,McEntire RL,Murphy EL,Retrovirus Epidemiology Donor Study.

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig)G replacement with intravenous or subcutaneous immunoglobulins is a lifelong substitutive therapy in patients with primary antibody deficiencies (PADs). Hemolysis after immunoglobulin therapy was described in patients receiving high immunoglobulin dosages. The issue of hemolysis after immu...

journal_title：Transfusion

authors： Quinti I,Pulvirenti F,Milito C,Granata G,Giovannetti G,La Marra F,Pesce AM,Farrugia A,Coluzzi S,Girelli G

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:During storage, the activity of the red blood cell (RBC) antioxidant system decreases. Glucose-6-phosphate dehydrogenase (G6PD) is essential for protection against oxidative stress by producing NADPH. G6PD function of RBC transfusion products is reported to remain stable during storage, but activity was meas...

journal_title：Transfusion

authors： Peters AL,van Bruggen R,de Korte D,Van Noorden CJ,Vlaar AP

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Variations in a multipass transmembrane protein may affect its membrane integration. To study this effect, the systematic molecular characterization of variant D antigen density is a suitable model. Unlike most other membrane proteins, the expression of the D antigen is often determined by a single allele, b...

journal_title：Transfusion

authors： Yu X,Wagner FF,Witter B,Flegel WA

更新日期：2006-08-01 00:00:00