Controlled-rate versus uncontrolled-rate freezing as predictors for platelet cryopreservation efficacy.

Abstract:

BACKGROUND:Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery was evaluated. STUDY DESIGN AND METHODS:PLTs (n = 33) were prepared from whole-blood units. Cell count and viability, PLT morphologic score (PMS), and hypotonic shock response were determined. PLT surface antigens were measured by flow cytometry. Controlled-rate (with compensated fusion heat) and uncontrolled-rate freezing methods combined with 6 percent dimethyl sulfoxide were used. RESULTS:PLT recovery was superior in the controlled-rate setting (91.0 +/- 5.5 vs. 86.0 +/- 6.5; p < 0.05). PMS was significantly better in controlled-rate freezing (p < 0.01). GPIb/CD42b expression was reduced in both freezing groups versus control. GP140/CD62p expression was significantly (p < 0.05) lower in the controlled-rate group and in both frozen groups was significantly higher than in the control groups. CONCLUSION:The use of strictly equalized (1 degrees C/min) controlled-rate freezing, combined with an intensified cooling rate (2 degrees C/min) during the liquid-to-solid-phase transition period, allows advanced quantitative and qualitative PLT recovery, even though the minor intergroup differences for some variables were observed.

journal_name

Transfusion

journal_title

Transfusion

authors

Balint B,Paunovic D,Vucetic D,Vojvodic D,Petakov M,Trkuljic M,Stojanovic N

doi

10.1111/j.1537-2995.2006.00706.x

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

230-5

issue

2

eissn

0041-1132

issn

1537-2995

pii

TRF00706

journal_volume

46

pub_type

杂志文章
  • Serologic evidence that Scianna null (Sc:-1,-2) red cells lack multiple high-frequency antigens.

    abstract::Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28488265264.x

    authors: Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

    更新日期:1988-07-01 00:00:00

  • Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin.

    abstract:BACKGROUND:The anti-CD20 monoclonal antibody rituximab has immune-modulatory effects similar to intravenous immunoglobulin (IVIG). We performed a systematic review and meta-analysis to determine the efficacy and safety of rituximab in autoimmune diseases that are also treated with IVIG. STUDY DESIGN AND METHODS:The mo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14841

    authors: MacIsaac J,Siddiqui R,Jamula E,Li N,Baker S,Webert KE,Evanovitch D,Heddle NM,Arnold DM

    更新日期:2018-11-01 00:00:00

  • Implementing mass-scale red cell genotyping at a blood center.

    abstract:BACKGROUND:When problems with compatibility beyond ABO and D arise, currently transfusion services search their inventories and perform time-consuming serologic testing to locate antigen-negative blood. These clinically important blood group antigens can be detected reliably by red cell genotyping, which is a technolog...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13168

    authors: Flegel WA,Gottschall JL,Denomme GA

    更新日期:2015-11-01 00:00:00

  • Implementation of a script for predonation interviews: impact on human immunodeficiency virus risk in South African blood donors.

    abstract:BACKGROUND:The way in which the donor history questionnaire is conducted plays a crucial role in the self-disclosure of behavioral risk factors for human immunodeficiency virus (HIV) infection by prospective donors. The South African National Blood Service changed its policy on the process of donor assessment in May 20...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15288

    authors: Mitchel J,Custer B,Kaidarova Z,Murphy EL,van den Berg K,Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) South Africa Program.

    更新日期:2019-07-01 00:00:00

  • Bartonella henselae transmission by blood transfusion in mice.

    abstract:BACKGROUND:Bartonella spp. are neglected fastidious Gram-negative bacilli. We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. Now, we aim to evaluate the possibility of B. henselae transm...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13545

    authors: Silva MN,Vieira-Damiani G,Ericson ME,Gupta K,Gilioli R,de Almeida AR,Drummond MR,Lania BG,de Almeida Lins K,Soares TC,Velho PE

    更新日期:2016-06-01 00:00:00

  • Hypersensitivity transfusion reactions to platelet concentrate: a retrospective analysis of the French hemovigilance network.

    abstract:BACKGROUND:Among labile blood products, platelet concentrates (PCs) are the leading cause of hypersensitivity transfusion reactions (HTRs). These reactions often lead to interruption of PC transfusion and can result in a prolonged transfusion process leading to significant morbidity and use of premedication and close m...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15275

    authors: Mertes PM,Tacquard C,Andreu G,Kientz D,Gross S,Malard L,Drouet C,Carlier M,Gachet C,Sandid I,Boudjedir K

    更新日期:2020-03-01 00:00:00

  • Anti-Ytb in pregnancy.

    abstract::Anti-Ytb was readily eluted from the cord red blood cells of the second child of a mother with both anti-Ytb and anti-Kell in her serum. The baby was Yt (a+b+) and Kell negative. The cord red blood cells were found to have a weakly positive direct antiglobulin test. Clinically evident hemolytic disease of the newborn ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1979.19580059814.x

    authors: Ferguson SJ,Boyce F,Blajchman MA

    更新日期:1979-09-01 00:00:00

  • Combination therapy of deferasirox and deferoxamine shows significant improvements in markers of iron overload in a patient with β-thalassemia major and severe iron burden.

    abstract:BACKGROUND:Iron overload is a common complication of patients with β-thalassemia major (TM). Despite the availability of three iron chelators, deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), some patients fail to respond adequately to monotherapy with any of them. We report a case of TM who had refractory...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12335

    authors: Voskaridou E,Komninaka V,Karavas A,Terpos E,Akianidis V,Christoulas D

    更新日期:2014-03-01 00:00:00

  • Absorption of anti-Chido from serum using autologous red blood cells coated with homologous C4.

    abstract::A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22382224951.x

    authors: Ellisor SS,Shoemaker MM,Reid ME

    更新日期:1982-05-01 00:00:00

  • Interactions of IgM ABO antibodies and complement with methoxy-PEG-modified human RBCs.

    abstract:BACKGROUND:RBCs modified with cyanuric chloride activated methoxy-PEG (CmPEG; 5000 Da) are less immunogenic than untreated RBCs, and their use thus may reduce the risk of alloimmunization in chronically transfused patients. STUDY DESIGN AND METHODS:To further examine the potential utility of CmPEG-RBCs, the effects of...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41101225.x

    authors: Bradley AJ,Test ST,Murad KL,Mitsuyoshi J,Scott MD

    更新日期:2001-10-01 00:00:00

  • Exchange transfusion in sickle cell disease using a continuous-flow blood cell separator.

    abstract::An exchange transfusion was performed preoperatively on a patient with sickle cell disease using a continuous-flow blood cell separator. An exchange of 2,825 ml red blood cells achieved a hemoglobin A level of 90.8 per cent. The continuous-flow blood cell separator appears to offer a safe and effective method of excha...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17377196364.x

    authors: Kernoff LM,Botha MC,Jacobs P

    更新日期:1977-05-01 00:00:00

  • Inositol hexaphosphate-loaded red blood cells prevent in vitro sickling.

    abstract:BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02663.x

    authors: Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

    更新日期:2010-10-01 00:00:00

  • Acute lung injury after blood transfusion in mechanically ventilated patients.

    abstract:BACKGROUND:Liberal transfusion strategy increases the risk of acute lung injury (ALI), but specific transfusion-related factors have not been characterized. We tested the hypotheses that storage age and specific type of blood products are associated with increased risk of ALI in mechanically ventilated patients. STUDY...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04053.x

    authors: Gajic O,Rana R,Mendez JL,Rickman OB,Lymp JF,Hubmayr RD,Moore SB

    更新日期:2004-10-01 00:00:00

  • Sensitivity of hepatitis C virus core antigen and antibody combination assays in a global panel of window period samples.

    abstract:BACKGROUND:Hepatitis C virus (HCV) antigen and antibody combination assays have been launched as a cost-effective alternative to nucleic acid testing (NAT) for reducing the antibody-negative window period (WP). Later, a HCV antigen chemiluminescence immunoassay (CLIA) became available. STUDY DESIGN AND METHODS:A panel...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13179

    authors: Laperche S,Nübling CM,Stramer SL,Brojer E,Grabarczyk P,Yoshizawa H,Kalibatas V,El Elkyabi M,Moftah F,Girault A,van Drimmelen H,Busch MP,Lelie N

    更新日期:2015-10-01 00:00:00

  • Prospective comparison of high-dose plateletpheresis with the latest apheresis systems on the same donors.

    abstract:BACKGROUND:To improve productivity of automated platelet (PLT) collection, the industry has introduced new instruments or modifications to existing equipment. STUDY DESIGN AND METHODS:With the same 8 donors for double (DDC) and triple-dose PLT collection (TDC), the Baxter Amicus (AM), the Haemonetics MCS Plus (MCS+), ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.00928.x

    authors: Picker SM,Radojska SM,Gathof BS

    更新日期:2006-09-01 00:00:00

  • Improved removal of white cells with minimal platelet loss by filtration of apheresis platelets during collection.

    abstract:BACKGROUND:Filtration of apheresis platelets to remove white cells (WBCs) requires operator intervention after the collection procedure (postcollection filtration), which may cause variable and unsatisfactory filter performance (WBC removal and platelet loss). The MCS+ LN9000 apheresis system filters platelets through ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1999.39199116898.x

    authors: Holme S,Andres M,Goermar N,Giordano GF

    更新日期:1999-01-01 00:00:00

  • Investigation of red blood cells from alpha1,3-galactosyltransferase-knockout pigs for human blood transfusion.

    abstract:BACKGROUND:Pigs are a potential source of red blood cells (RBCs) for transfusion into humans, but the presence of galactose-alpha1,3-galactose (Gal) epitopes on their surface, against which humans have anti-Gal, has been perceived as a major barrier. alpha1,3-Galactosyltransferase gene-knockout pigs, which do not expre...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04002.x

    authors: Rouhani FJ,Dor FJ,Cooper DK

    更新日期:2004-07-01 00:00:00

  • Effects of hydroxyethyl starch on blood coagulation, particularly factor VIII.

    abstract::The effects of hydroxyethyl starch (HES) on hemostasis were investigated extensively. In order to simulate acute blood loss due to surgery or trauma, one unit (450 ml) of blood was drawn from normal healthy men. This was followed by a 1-liter infusion over 60 minutes of either 6 percent HES, 5 percent albumin, or 0.9 ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1985.25485273815.x

    authors: Stump DC,Strauss RG,Henriksen RA,Petersen RE,Saunders R

    更新日期:1985-07-01 00:00:00

  • Ultrastructural localization of glycoprotein IIIa (GPIIIa, beta 3 integrin) on placental syncytiotrophoblast microvilli: implications for platelet alloimmunization during pregnancy.

    abstract:BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a more commonly occurs in first pregnancies, unlike hemolytic disease of the newborn. Anti-D is produced after D+ fetomaternal hemorrhage; this usually occurs at parturition. Anti-HPA-1a could develop during pregnancy if...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01832.x

    authors: Kumpel BM,Sibley K,Jackson DJ,White G,Soothill PW

    更新日期:2008-10-01 00:00:00

  • Lifeline for the front lines: blood products to support the warfighter.

    abstract:BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15165

    authors: Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

    更新日期:2019-04-01 00:00:00

  • A sensitive quantitative single-platform flow cytometry protocol to measure human platelets in mouse peripheral blood.

    abstract:BACKGROUND:The NOD/SCID mouse is a widely used model for human cord blood (CB) transplantation. Engraftment is generally estimated with semiquantitative methods, measuring the percentage of human cells among mouse cells. To compare protocols aiming to improve hematopoietic recovery, quantitative methods to enumerate hu...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01472.x

    authors: Schipper LF,van Hensbergen Y,Fibbe WE,Brand A

    更新日期:2007-12-01 00:00:00

  • DAK, a new low-incidence antigen in the Rh blood group system.

    abstract:BACKGROUND:Some low-incidence antigens in the Rh blood group system (e.g., VS, Rh32, FPTT) are expressed by more than one Rh complex. We describe a new low-incidence antigen that is present on RBCs with the partial D phenotypes, DIIIa or DOL, on RN RBCs and on one example of STEM+S RBCs. STUDY DESIGN AND METHODS:Stand...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00517.x

    authors: Reid ME,Storry JR,Sausais L,Tossas E,Rios M,Hue-Roye K,Gloster ES,Miller ST,Wolf C,Lomas-Francis C

    更新日期:2003-10-01 00:00:00

  • Longitudinal monitoring of WBC subsets in packed RBC units after filtration: implications for transfusion transmission of infections.

    abstract:BACKGROUND:Specific subsets of peripheral blood WBCs are reservoirs for infectious agents, such as CMV and EBV, and can serve as vectors for transfusion transmission of these agents. While filter WBC reduction has been used to prevent transfusion transmission of infections, its effectiveness has not been documented for...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40050500.x

    authors: Roback JD,Bray RA,Hillyer CD

    更新日期:2000-05-01 00:00:00

  • A randomized, double-blind comparison of donor tolerance of 400 mL, 200 mL, and sham red cell donation.

    abstract:BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1537-2995.1996.36896374369.x

    authors: Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

    更新日期:1996-08-01 00:00:00

  • Duration of platelet storage and outcomes of critically ill patients.

    abstract:BACKGROUND:The storage duration of platelet (PLT) units is limited to 5 to 7 days. This study investigates whether PLT storage duration is associated with patient outcomes in critically ill patients. STUDY DESIGN AND METHODS:This study was a retrospective analysis of critically ill patients admitted to the intensive c...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.14056

    authors: Flint A,Aubron C,Bailey M,Bellomo R,Pilcher D,Cheng AC,Hegarty C,Reade MC,McQuilten Z

    更新日期:2017-03-01 00:00:00

  • Evaluation of the National Healthcare Safety Network Hemovigilance Module for transfusion-related adverse reactions in the United States.

    abstract:INTRODUCTION:The National Healthcare Safety Network (NHSN) Hemovigilance Module (HM) collects data on the frequency, severity, and imputability of transfusion-associated adverse events. These events contribute to significant morbidity and mortality among transfusion patients. We report results from the first systematic...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15008

    authors: Edens C,Haass KA,Cumming M,Osinski A,O'Hearn L,Passanisi K,Eaton L,Visintainer P,Savinkina A,Kuehnert MJ,Basavaraju SV,Andrzejewski C

    更新日期:2019-02-01 00:00:00

  • Platelet transfusion: automated selection of donors.

    abstract::The selection of platelet donors, according to HLA antigens, has been computerized using a method based on the calculation of incompatibilities and risk of immunization between donors and recipients. Since the risk that an antigen present in a donor will immunize an incompatible recipient of known HLA phenotype, an in...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1981.21381201795.x

    authors: Muller JY,Cartron JP,Trillot P,Halle L,Roquin H

    更新日期:1981-05-01 00:00:00

  • Trends in antigen-negative red blood cell distributions by racial or ethnic groups in the United States.

    abstract:BACKGROUND:The overall number of red blood cell (RBC) units distributed to hospitals throughout the world and in the United States has decreased lately. This study was performed to determine if the number of antigen-negative RBC units distributed to hospitals has followed this trend. STUDY DESIGN AND METHODS:Stratifie...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14376

    authors: Yazer MH,Anani WQ,Denomme GA,Karafin MS,Sayers M,Shaz BH,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

    更新日期:2018-01-01 00:00:00

  • A novel approach for rapid detection of bacterially contaminated platelet concentrates via sensitive measurement of microbial DNA polymerase activity.

    abstract:BACKGROUND:Transfusion of bacterially contaminated platelet concentrates (PCs) can result in serious health consequences for the affected patient. Before being released from blood banking facilities, PCs are routinely screened for bacterial contamination by culture-based tests. However, culture-based PC screening metho...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12487

    authors: Zweitzig DR,Riccardello NM,Pester JM,Jeanmonod R,Kopnitsky MJ,O'Hara SM

    更新日期:2014-06-01 00:00:00

  • A revised classification scheme for acute transfusion reactions.

    abstract:BACKGROUND:Although the standard classification system for acute transfusion reactions adequately describes the general features associated with the various types of reactions, it was not designed to provide strict criteria for diagnosis and classification. Consequently, its use to classify individual reactions can res...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01163.x

    authors: Sanders RP,Geiger TL,Heddle N,Pui CH,Howard SC

    更新日期:2007-04-01 00:00:00