Abstract:
:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible with a sibling's Sc:1,-2 cells. Cross-testing cells with sera or eluates, or both, from the three persons revealed no mutual compatibility. These studies show the existence of three additional RBC antigens phenotypically related to the Scianna blood group system. Sc:-1,-2 cells lack these antigens, which indicates that Scianna null cells lack multiple high-frequency antigens.
journal_name
Transfusionjournal_title
Transfusionauthors
Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HFdoi
10.1046/j.1537-2995.1988.28488265264.xsubject
Has Abstractpub_date
1988-07-01 00:00:00pages
346-9issue
4eissn
0041-1132issn
1537-2995journal_volume
28pub_type
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