Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome.

abstract：BACKGROUND:Prototypes of platelet (PLT) substitutes have been studied and the focus was on a dodecapeptide, HHLGGAKQAGDV (H12), which is a fibrinogen gamma-chain carboxy-terminal sequence (gamma 400-411) and exists only in the fibrinogen domain. STUDY DESIGN AND METHODS:H12 was conjugated to the surface of polymerized...

journal_title：Transfusion

authors： Okamura Y,Takeoka S,Teramura Y,Maruyama H,Tsuchida E,Handa M,Ikeda Y

更新日期：2005-07-01 00:00:00

abstract：:Our computer system currently stores donor blood types for seven years and checks typing of all repeat donors against these files. In a recent three-month period (42,500 units), five discrepancies were found--two representing current error. Retrospective analysis of 18 errors made over the last three years showed that...

journal_title：Transfusion

authors： Grindon AJ,Liles BA

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA,Houtz T

更新日期：1994-02-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:The operational and analytical performance of two automated triplex hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service. STUDY DESIGN AND METHODS:Two laboratories eva...

journal_title：Transfusion

authors： Assal A,Barlet V,Deschaseaux M,Dupont I,Gallian P,Guitton C,Morel P,David B,De Micco P

更新日期：2009-02-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:To minimize the bacterial contamination rate in blood collected from donors, a study was designed to evaluate the suitability of a single-use chlorhexidine-alcohol antiseptic for donor arm preparation at all blood collection venues in Australia. STUDY DESIGN AND METHODS:A prospective study of bacterial load...

journal_title：Transfusion

authors： Wong PY,Colville VL,White V,Walker HM,Morris RA,Microbial Contamination and Infection Control Subcommittee, Australian Red Cross Blood Service.

更新日期：2004-08-01 00:00:00

abstract：:Extracellular vesicles (EVs) are small, subcellular vesicles that are released from a variety of cells and play important roles in cell-to-cell communication. Transfused blood products, including red blood cell, platelet, and plasma products contain EVs that are capable of interacting with and altering immune cell fun...

journal_title：Transfusion

authors： Menocha S,Muszynski JA

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...

journal_title：Transfusion

authors： Wang B,Schreiber GB,Glynn SA,Nass CC,Smith JW,Higgins MJ,Hutching ST,Wright DJ,McEntire RL,Murphy EL,Retrovirus Epidemiology Donor Study.

更新日期：2003-06-01 00:00:00

abstract：:Adenine is an approved additive to citrate-phosphate-dextrose anticoagulant for whole blood collection and extends the storage life of red blood cells. We used in vitro methods to investigate the effects of adenine on platelet function and viability during 72 hours of storage at 22 degrees C. Although the hypotonic sh...

journal_title：Transfusion

authors： Wong SC,Rock G

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Deterioration in quality of platelet concentrates (PCs) during storage results from the appearance of storage lesions affecting the hemostatic functions and posttransfusion survival of platelets. These lesions depend on the preparation and pathogen inactivation methods used, duration of storage, and platelet...

journal_title：Transfusion

authors： Isola H,Ravanat C,Rudwill F,Pongerard A,Haas D,Eckly A,Gachet C,Hechler B

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：:An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

journal_title：Transfusion

authors： Halima D,Garratty G,Bueno R

更新日期：1982-11-01 00:00:00

abstract：:A new blood pack system for the preparation of white cell-depleted red cells was studied. The system is a modified additive-solution quadruple-unit blood pack that incorporates a cellulose-acetate fiber depth filter in-line between the AS-3 additive bag and the CP2D collection bag. Mean +/- SD white cell removal from ...

journal_title：Transfusion

authors： Davey RJ,Carmen RA,Simon TL,Nelson EJ,Leng BS,Chong C,Garcez RB,Sohmer PR

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Washing of red blood cell concentrates (RCCs) is required for potassium-sensitive transfusion recipients, including neonates in need of large-volume transfusions. When open, nonsterile washing systems are used, postwash outdate time is limited to 24 hours, often leading to problems providing the component to...

journal_title：Transfusion

authors： Hansen A,Yi QL,Acker JP

更新日期：2013-08-01 00:00:00

abstract：:Two patients with naturally occurring anti-K agglutinins are reported. Both patients manifested clinical symptoms associated with septicemia. Transfusion of one patient with K-positive blood did not result in hemolytic complications, further stimulation of the anti-K agglutinin or any change in its immunoglobulin natu...

journal_title：Transfusion

authors： Judd WJ,Walter WJ,Steiner EA

更新日期：1981-03-01 00:00:00

abstract：:Cryoprecipitate is used infrequently in home therapy for patients with hemophilia A since freezer storage is required and resuspension and pooling of thawed cryoprecipitate is cumbersome. We evaluated procedures for preparation of cryoprecipitate in an "open system" so that four to six bags of cryoprecipitate could be...

journal_title：Transfusion

authors： Smith KJ,Hodges PA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Pulmonary endothelial cell damages caused by neutrophil overactivation could result in acute lung injuries including transfusion-related acute lung injury (TRALI). We previously reported that heme-related molecules derived from hemolysis induced the production of reactive oxygen species from neutrophils. Rec...

journal_title：Transfusion

authors： Kono M,Saigo K,Takagi Y,Takahashi T,Kawauchi S,Wada A,Hashimoto M,Minami Y,Imoto S,Takenokuchi M,Morikawa T,Funakoshi K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Identification of antibodies against high-prevalence Scianna (Sc; ERMAP) antigens, like Sc1 and Sc5, is difficult and may incur delays in blood procurement and costs. The detection of additional clinically significant alloantibodies is hampered in the presence of anti-Scianna. Soluble recombinant Scianna pro...

journal_title：Transfusion

authors： Seltsam A,Grueger D,Blasczyk R,Flegel WA

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Tranexamic acid (TXA) has been reported to demonstrate efficacy in reducing blood loss during arthroplasty procedures. STUDY DESIGN AND METHODS:This study examines the effectiveness of TXA as a central element of a patient blood management program (PBMP) by evaluating blood loss and transfusion of red blood...

journal_title：Transfusion

authors： Pitta M,Zawadsky M,Verstraete R,Rubinstein A

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is reported to occur at an incidence of 5.2% to 23.5% among patients with thalassemia requiring chronic transfusion. With very limited data on alloimmunization among the Chinese population, a territory-wide study has been performed to look at its prevalence among Chinese...

journal_title：Transfusion

authors： Cheng CK,Lee CK,Lin CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cell-free fetal DNA in maternal plasma opens the way for routine risk-free diagnosis of fetal D status of D- mothers. The focus was on accuracy of RHD typing and confirmation of fetal DNA in maternal plasma while RHD was not detected. STUDY DESIGN AND METHODS:Plasma DNA was extracted (by manual and/or autom...

journal_title：Transfusion

authors： Brojer E,Zupanska B,Guz K,Orziñska A,Kaliñska A

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect. STUDY DESIGN AND METHODS:The concentration of BK and one of its vasoactive metabolites, des-arginine(9)-BK (des-Arg(9)...

journal_title：Transfusion

authors： Moreau ME,Thibault L,Désormeaux A,Chagnon M,Lemieux R,Robillard P,Marceau F,Colman RW,Lepage Y,Rivard GE,Adam A

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Human parvovirus B19 is a common human pathogen that causes a variety of diseases with outcomes ranging from asymptomatic to severe, especially in immunocompromised patients. The B19 virus can be transmitted via blood and/or blood products and its resistance to common viral inactivation and/or removal method...

journal_title：Transfusion

authors： Ke L,He M,Li C,Liu Y,Gao L,Yao F,Li J,Bi X,Lv Y,Wang J,Hirsch ML,Li W

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is common in transfused patients. Most studies report on the rate of alloimmunization in chronically transfused patients, which can be as high as 60 percent. Less is known on the incidence of clinically relevant antibodies in accidentally transfused patients. Because the...

journal_title：Transfusion

authors： Schonewille H,van de Watering LM,Brand A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) units stored for more than 2 weeks at 4 degrees C are currently considered of impaired quality. This opinion has primarily been based on altered RBC rheologic properties (i.e., enhanced aggregability, reduced deformability, and elevated endothelial cell interaction), during prolonged sto...

journal_title：Transfusion

authors： Henkelman S,Dijkstra-Tiekstra MJ,de Wildt-Eggen J,Graaff R,Rakhorst G,van Oeveren W

更新日期：2010-04-01 00:00:00

abstract：:Preoperative autologous blood donation for elective surgery patients at university hospitals was underused in the past. More recently, national educational efforts have been made. To test the impact of local surgeon interviews and education, in 1988 the same local educational program was instituted at three university...

journal_title：Transfusion

authors： Toy PT,McVay PA,Strauss RG,Stehling LC,Ahn DK

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the effects of red blood cell (RBC) transfusion on the hemorrheologic properties and microcirculatory hemodynamics in anemic hematology outpatients receiving 2 to 4 RBC units of either "fresh" (leukoreduced storage for less than 1 week) or "aged" (leukoreduced storage...

journal_title：Transfusion

authors： Yürük K,Milstein DM,Bezemer R,Bartels SA,Biemond BJ,Ince C

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00